$107+ Cheap flights from South Carolina to Guatemala
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GUA
May 4 — May 111
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to GuatemalaExplore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.
Explore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Sat 4/2511:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:55 am
CLT
- GUA
1 stop23h 33m
Multiple Airlines
Tue 4/76:38 pm
GUA
- CLT
1 stop15h 29m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$264
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:58 pm
CLT
- GUA
1 stop12h 32m
Multiple Airlines
Tue 4/712:23 pm
GUA
- CLT
1 stop10h 15m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$265
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
CLT
- GUA
1 stop21h 01m
Spirit Airlines
Fri 4/1711:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:00 am
CLT
- GUA
1 stop27h 28m
Multiple Airlines
Wed 4/811:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:46 pm
CLT
- GUA
1 stop23h 46m
Multiple Airlines
Wed 4/811:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:00 am
CLT
- GUA
1 stop27h 28m
Multiple Airlines
Fri 4/1011:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:46 pm
CLT
- GUA
1 stop23h 46m
Multiple Airlines
Fri 4/1011:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$282
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Mon 4/2011:51 am
GUA
- CLT
2 stops19h 19m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$284
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:58 pm
CLT
- GUA
1 stop12h 32m
Frontier
Thu 4/99:43 am
GUA
- CLT
1 stop10h 04m
Frontier
Deal found 3/31![Frontier logo]()
$293
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MYR
- GUA
1 stop7h 12m
Spirit Airlines
Thu 5/2112:17 pm
GUA
- MYR
1 stop6h 19m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$336
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
MYR
- GUA
1 stop7h 12m
Spirit Airlines
Sun 5/1012:17 pm
GUA
- MYR
1 stop6h 19m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$346
Best flights from South Carolina to GuatemalaDiscover carefully curated flight deals from South Carolina to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 4, 2026.
Discover carefully curated flight deals from South Carolina to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 4, 2026.
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MYR
- GUA
1 stop7h 12m
Spirit Airlines
Thu 5/2112:17 pm
GUA
- MYR
1 stop6h 19m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:48 pm
CHS
- GUA
1 stop13h 35m
Multiple Airlines
Sun 5/108:15 pm
GUA
- CHS
2 stops35h 43m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$436
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:20 am
CHS
- GUA
1 stop8h 26m
Delta
Fri 4/241:14 pm
GUA
- CHS
1 stop8h 11m
Delta
Deal found 3/30![Delta logo]()
$491
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:14 am
CHS
- GUA
1 stop9h 29m
American Airlines
Thu 5/141:01 pm
GUA
- CHS
1 stop9h 23m
American Airlines
Deal found 4/2![American Airlines logo]()
$491
This Copa Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:44 pm
CLT
- GUA
3 stops27h 53m
Copa Airlines
Fri 8/212:28 am
GUA
- CLT
2 stops29h 14m
Copa Airlines
Deal found 4/3![Copa Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
CHS
- GUA
2 stops12h 37m
United Airlines
Sun 4/1911:55 pm
GUA
- CHS
1 stop8h 28m
United Airlines
Deal found 4/3![United Airlines logo]()
$561
This Expedia deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:45 am
SAV
- GUA
1 stop26h 03m
JetBlue
Mon 4/272:10 pm
GUA
- SAV
1 stop17h 45m
JetBlue
Deal found 4/2![JetBlue logo]()
$701
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:52 am
MYR
- GUA
1 stop25h 13m
Spirit Airlines
Tue 4/2812:15 pm
GUA
- MYR
1 stop18h 26m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:21 pm
CHS
- GUA
2 stops13h 10m
American Airlines
Sat 5/3012:35 am
GUA
- CHS
1 stop12h 18m
American Airlines
Deal found 3/31![American Airlines logo]()
$500
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:31 pm
MYR
- GUA
2 stops40h 25m
Spirit Airlines
Sun 4/2612:10 pm
GUA
- MYR
1 stop9h 19m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:24 am
MYR
- GUA
2 stops24h 36m
Multiple Airlines
Fri 6/57:10 pm
GUA
- MYR
1 stop12h 36m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:09 pm
CHS
- GUA
1 stop19h 53m
American Airlines
Mon 5/46:00 am
GUA
- CHS
1 stop16h 24m
American Airlines
Deal found 3/30![American Airlines logo]()
$501
This Copa Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:49 pm
CLT
- GUA
2 stops14h 57m
Copa Airlines
Sat 8/226:24 am
GUA
- CLT
3 stops25h 18m
Copa Airlines
Deal found 4/3![Copa Airlines logo]()
$559
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:20 am
CHS
- GUA
1 stop8h 26m
Delta
Sun 4/191:14 pm
GUA
- CHS
1 stop7h 48m
Delta
Deal found 3/31![Delta logo]()
$561
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:25 pm
SAV
- GUA
1 stop8h 15m
United Airlines
Tue 9/86:15 am
GUA
- SAV
1 stop13h 38m
United Airlines
Deal found 4/2![United Airlines logo]()
$575
This FlightHub deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:45 am
SAV
- GUA
2 stops24h 15m
Multiple Airlines
Mon 5/43:40 pm
GUA
- SAV
2 stops16h 12m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$559
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:31 pm
MYR
- GUA
2 stops18h 04m
Spirit Airlines
Sat 8/11:28 pm
GUA
- MYR
1 stop5h 57m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$528
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
CLT
- GUA
3 stops17h 41m
Copa Airlines
Mon 5/251:01 pm
GUA
- CLT
2 stops18h 44m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$589
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
MYR
- GUA
1 stop7h 31m
Delta
Mon 5/111:01 pm
GUA
- MYR
1 stop8h 57m
Delta
Deal found 4/1![Delta logo]()
$599
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:00 am
CHS
- GUA
2 stops15h 43m
American Airlines
Sun 5/103:14 pm
GUA
- CHS
2 stops17h 13m
American Airlines
Deal found 4/3![American Airlines logo]()
$555
This oojo deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:42 am
SAV
- GUA
1 stop21h 18m
Multiple Airlines
Mon 5/43:40 pm
GUA
- SAV
2 stops16h 12m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$588
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:21 pm
MYR
- GUA
2 stops22h 03m
United Airlines
Sat 10/310:47 pm
GUA
- MYR
1 stop8h 11m
United Airlines
Deal found 4/1![United Airlines logo]()
$647
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:46 am
CLT
- GUA
1 stop7h 00m
Delta
Mon 5/111:01 pm
GUA
- CLT
1 stop6h 58m
Delta
Deal found 3/30![Delta logo]()
$613
This Copa Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
CLT
- GUA
3 stops17h 41m
Copa Airlines
Mon 5/256:24 am
GUA
- CLT
3 stops25h 21m
Copa Airlines
Deal found 4/3![Copa Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:30 am
CAE
- GUA
2 stops11h 00m
American Airlines
Thu 8/2712:27 pm
GUA
- CAE
2 stops20h 20m
American Airlines
Deal found 3/31![American Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:38 pm
CAE
- GUA
2 stops17h 47m
United Airlines
Tue 5/2611:55 pm
GUA
- CAE
1 stop12h 21m
United Airlines
Deal found 4/3![United Airlines logo]()
$672
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CLT
- GUA
3 stops17h 41m
Copa Airlines
Sat 5/1610:35 am
GUA
- CLT
2 stops21h 18m
Copa Airlines
Deal found 3/31![Copa Airlines logo]()
$615
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MYR
- GUA
1 stop7h 46m
Delta
Tue 5/51:14 pm
GUA
- MYR
1 stop9h 00m
Delta
Deal found 3/31![Delta logo]()
$647
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:59 pm
AGS
- GUA
1 stop23h 25m
American Airlines
Thu 10/1512:04 pm
GUA
- AGS
1 stop9h 23m
American Airlines
Deal found 4/2![American Airlines logo]()
$608
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:39 pm
MYR
- GUA
2 stops15h 33m
Multiple Airlines
Tue 5/51:55 pm
GUA
- MYR
3 stops28h 41m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$685
Last-minute flights from South Carolina to GuatemalaDiscover last-minute flight deals from South Carolina to Guatemala. Data last updated April 4, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Guatemala. Data last updated April 4, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:58 pm
CLT
- GUA
1 stop12h 32m
Frontier
Wed 4/89:02 am
GUA
- CLT
1 stop11h 53m
Frontier
Deal found 3/31![Frontier logo]()
$293
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:58 pm
CLT
- GUA
1 stop12h 32m
Frontier
Mon 4/612:37 pm
GUA
- CLT
1 stop9h 59m
Frontier
Deal found 3/31![Frontier logo]()
$303
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
CLT
- GUA
1 stop21h 01m
Spirit Airlines
Fri 4/1711:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:07 am
CHS
- GUA
1 stop5h 17m
Multiple Airlines
Fri 4/1711:51 am
GUA
- CHS
2 stops24h 14m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$388
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Sat 4/2511:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$260
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Mon 4/2011:51 am
GUA
- CLT
2 stops19h 19m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$284
This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Fri 5/111:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Sat 5/912:17 pm
GUA
- CLT
1 stop9h 23m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$299
This CheapOair deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Thu 4/3012:10 pm
GUA
- CLT
2 stops17h 59m
Spirit Airlines
Deal found 4/3![Spirit Airlines logo]()
$297
This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Tue 5/512:17 pm
GUA
- CLT
1 stop9h 23m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$301
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
MYR
- GUA
1 stop7h 12m
Spirit Airlines
Sun 5/1012:17 pm
GUA
- MYR
1 stop6h 19m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$346
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MYR
- GUA
1 stop7h 12m
Spirit Airlines
Thu 5/2112:17 pm
GUA
- MYR
1 stop6h 19m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$336
One-way flights from South Carolina to GuatemalaSearch for one-way flight options from South Carolina to Guatemala. Find affordable one-way fares based on user searches. Data last updated April 4, 2026.
Search for one-way flight options from South Carolina to Guatemala. Find affordable one-way fares based on user searches. Data last updated April 4, 2026.
This CheapOair deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Deal found 4/3![Spirit Airlines logo]()
$107
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:07 am
CHS
- GUA
1 stop5h 17m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$117
This Super.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:54 pm
CLT
- GUA
1 stop15h 16m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:13 pm
CLT
- GUA
2 stops38h 52m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$133
This Super.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/139:07 pm
CLT
- GUA
1 stop16h 05m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$147
This Trip.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:41 pm
CLT
- GUA
1 stop18h 31m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$149
This Priceline deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:58 pm
CLT
- GUA
1 stop20h 44m
Frontier
Deal found 4/2![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:30 am
CLT
- GUA
3 stops14h 00m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:49 pm
CHS
- GUA
2 stops39h 46m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:12 am
CLT
- GUA
2 stops30h 00m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:39 pm
CHS
- GUA
3 stops22h 54m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$222
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:50 pm
CHS
- GUA
2 stops15h 18m
American Airlines
Deal found 3/31![American Airlines logo]()
$232
Find flight deals from South Carolina to Guatemala
Keep the following information in mind while searching for South Carolina to Guatemala flight deals. Data was last updated April 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $260 (CheapOair) |
One-way from | $107 (CheapOair) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from South Carolina to Guatemala that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Thu 5/14
6:00 am-11:12 am
1 stop7h 12m
Guatemala City La Aurora
Thu 5/21
12:17 pm-8:36 pm
1 stop6h 19m
$336
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Sat 4/25
11:52 am-11:05 am
1 stop25h 13m
Guatemala City La Aurora
Tue 4/28
12:15 pm-8:41 am
1 stop18h 26m
$408
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Sun 5/3
10:48 pm-10:23 am
1 stop13h 35m
Guatemala City La Aurora
Sun 5/10
8:15 pm-9:58 am
2 stops35h 43m
$436
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Thu 4/23
8:31 pm-10:56 am
2 stops40h 25m
Guatemala City La Aurora
Sun 4/26
12:10 pm-11:29 pm
1 stop9h 19m
$459
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Tue 4/21
5:20 am-11:46 am
1 stop8h 26m
Guatemala City La Aurora
Fri 4/24
1:14 pm-11:25 pm
1 stop8h 11m
$491
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Thu 5/7
11:14 am-6:43 pm
1 stop9h 29m
Guatemala City La Aurora
Thu 5/14
1:01 pm-12:24 am
1 stop9h 23m
$491
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Thu 5/28
12:21 pm-11:31 pm
2 stops13h 10m
Guatemala City La Aurora
Sat 5/30
12:35 am-2:53 pm
1 stop12h 18m
$500
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Mon 4/27
8:09 pm-2:02 pm
1 stop19h 53m
Guatemala City La Aurora
Mon 5/4
6:00 am-12:24 am
1 stop16h 24m
$501
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Tue 6/2
10:24 am-9:00 am
2 stops24h 36m
Guatemala City La Aurora
Fri 6/5
7:10 pm-9:46 am
1 stop12h 36m
$523
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Fri 5/1
8:31 pm-12:35 pm
2 stops18h 04m
Guatemala City La Aurora
Sat 8/1
1:28 pm-9:25 pm
1 stop5h 57m
$528
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Guatemala
Have a flexible travel schedule? Discover the best time to fly to Guatemala from South Carolina with our price prediction graph.
CLT-GUA
MYR-GUA
CHS-GUA
CAE-GUA
GSP-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Guatemala
USSC-GT0
CLT-GUA
MYR-GUA
CHS-GUA
CAE-GUA
What is the cheapest month to book a flight from South Carolina to Guatemala?
Currently, April is the cheapest month in which you can book a flight from South Carolina to Guatemala (average of $107). Flying from South Carolina to Guatemala in December is currently the most expensive (average of $602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to GT?
Find hourly flight availability from South Carolina to Guatemala. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 4, 2026.
A simple way to save on the total cost of your ticket is to fly from South Carolina to Guatemala in the evening. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the morning.
What is the cheapest day to fly from South Carolina to Guatemala?
Use this chart to determine the cheapest time to fly round-trip from South Carolina to Guatemala. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their South Carolina to Guatemala flight should consider departing on Monday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Guatemala
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Guatemala by cabin class
Find flights from South Carolina to Guatemala, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Guatemala flights
Browse other South Carolina and Guatemala flight options. Last updated on April 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Guatemala
Find the right flight back to South Carolina after your stay in Guatemala
South Carolina to Guatemala flights
Consider these flights traveling from South Carolina to Guatemala.
Top 3 airlines flying from South Carolina to Guatemala
Discover the top 3 airlines that operate flights from South Carolina to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$536 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$400 | Average$545 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$402 | Average$755 | FlexibilityNo cancel fee | On-timeN/A |