$260+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to Guatemala City
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Cheapest flights from Santiago to Guatemala CityExplore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:30 am -
1 stop14h 30m
Mon 12/289:20 am -
1 stop12h 45m
Deal found 9/5![Avianca logo]()
$508
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:15 pm -
1 stop23h 31m
Wed 12/304:18 am -
1 stop20h 28m
Deal found 9/5![Copa Airlines logo]()
$516
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:31 am -
1 stop13h 16m
Thu 11/52:22 am -
1 stop18h 14m
Deal found 9/7![Copa Airlines logo]()
$523
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 am -
1 stop11h 17m
Mon 11/236:24 am -
2 stops14h 55m
Deal found 9/7![Copa Airlines logo]()
$527
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:02 am -
1 stop11h 37m
Mon 1/184:18 am -
1 stop13h 00m
Deal found 9/6![Copa Airlines logo]()
$531
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:10 am -
1 stop13h 55m
Mon 12/149:20 am -
1 stop17h 25m
Deal found 9/5![Avianca logo]()
$536
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:28 am -
1 stop11h 19m
Wed 11/47:16 am -
1 stop13h 20m
Deal found 9/7![Copa Airlines logo]()
$538
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:22 am -
1 stop10h 24m
Tue 11/1710:41 am -
1 stop10h 38m
Deal found 9/9![Copa Airlines logo]()
$542
This FlightHub deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/287:30 am -
1 stop32h 35m
Wed 1/202:00 pm -
1 stop32h 05m
Deal found 9/6![Avianca logo]()
$551
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:19 am -
1 stop19h 32m
Tue 11/241:08 pm -
1 stop10h 40m
Deal found 9/7![Copa Airlines logo]()
$561
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:15 am -
1 stop11h 32m
Sun 10/184:20 am -
1 stop16h 19m
Deal found 9/6![Copa Airlines logo]()
$563
Best flights from Santiago to Guatemala CityDiscover carefully curated flight deals from Santiago to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Santiago to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:15 pm -
1 stop23h 31m
Wed 12/27:17 am -
1 stop17h 26m
Deal found 9/5![Copa Airlines logo]()
$516
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:02 am -
1 stop11h 37m
Thu 11/121:08 pm -
1 stop11h 30m
Deal found 9/6![Copa Airlines logo]()
$516
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:48 am -
2 stops20h 48m
Tue 5/185:59 am -
2 stops11h 08m
Deal found 9/8![Copa Airlines logo]()
$531
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:19 am -
1 stop19h 32m
Tue 11/241:08 pm -
1 stop10h 40m
Deal found 9/5![Copa Airlines logo]()
$531
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:15 pm -
1 stop23h 31m
Fri 12/46:24 am -
2 stops14h 54m
Deal found 9/8![Copa Airlines logo]()
$531
Last-minute flights from Santiago to Guatemala CityDiscover last-minute flight deals from Santiago to Guatemala City. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Guatemala City. Data last updated September 9, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:06 am -
1 stop11h 27m
Sun 9/204:20 am -
1 stop17h 02m
Deal found 9/7![Copa Airlines logo]()
$561
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:14 am -
1 stop20h 53m
Thu 9/176:24 am -
2 stops14h 15m
Deal found 9/7![Copa Airlines logo]()
$546
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:40 am -
1 stop32h 20m
Mon 9/219:45 pm -
2 stops29h 00m
Deal found 9/8![Avianca logo]()
$565
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:14 am -
2 stops19h 22m
Sat 10/176:24 am -
2 stops14h 15m
Deal found 9/7![Copa Airlines logo]()
$578
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:22 am -
2 stops19h 14m
Mon 10/56:24 am -
2 stops18h 32m
Deal found 9/7![Copa Airlines logo]()
$531
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:30 am -
1 stop14h 30m
Mon 12/289:20 am -
1 stop12h 45m
Deal found 9/5![Avianca logo]()
$508
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:23 pm -
2 stops12h 13m
Sun 10/186:24 am -
2 stops11h 08m
Deal found 9/6![Copa Airlines logo]()
$563
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:23 pm -
2 stops12h 13m
Mon 12/286:24 am -
2 stops18h 19m
Deal found 9/6![Copa Airlines logo]()
$516
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:31 am -
1 stop13h 16m
Thu 11/52:22 am -
1 stop18h 14m
Deal found 9/7![Copa Airlines logo]()
$523
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:28 am -
1 stop11h 19m
Wed 11/47:16 am -
1 stop13h 20m
Deal found 9/7![Copa Airlines logo]()
$538
One-way flights from Santiago to Guatemala CitySearch for one-way flight options from Santiago to Guatemala City. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Santiago to Guatemala City. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:30 pm -
2 stops34h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:35 pm -
2 stops27h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$261
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:43 am -
1 stop10h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$262
This Mytrip deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop13h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Arajet logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:12 pm -
2 stops25h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$275
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/95:18 am -
2 stops19h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1511:27 am -
2 stops36h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:22 pm -
2 stops12h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Copa Airlines logo]()
$289
This Avianca deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:20 pm -
1 stop12h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Avianca logo]()
$297
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:19 am -
2 stops21h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Copa Airlines logo]()
$309
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/164:15 pm -
1 stop23h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Avianca logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:07 am -
2 stops41h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$322
Find flight deals from Santiago to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $508 (Avianca) |
One-way from | $260 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $533 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 9/16
12:22 pm-11:47 am
1 stop26h 25m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$309
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Sat 10/31
3:19 am-9:36 pm
2 stops21h 17m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$309
Quickest round-trip
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Mon 11/30
1:27 am-8:46 am
1 stop10h 19m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$309
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 12/2
1:27 am-9:40 am
1 stop11h 13m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$309
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 1/20
1:12 am-11:51 am
1 stop13h 39m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$324
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Thu 11/26
12:15 pm-8:46 am
1 stop23h 31m
Guatemala City La Aurora
Wed 12/2
7:17 am-3:43 am
1 stop17h 26m
$516
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 11/4
1:02 am-9:39 am
1 stop11h 37m
Guatemala City La Aurora
Thu 11/12
1:08 pm-3:38 am
1 stop11h 30m
$516
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Fri 11/20
3:48 am-9:36 pm
2 stops20h 48m
Guatemala City La Aurora
Tue 5/18
5:59 am-7:07 pm
2 stops11h 08m
$531
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Fri 11/13
3:19 am-7:51 pm
1 stop19h 32m
Guatemala City La Aurora
Tue 11/24
1:08 pm-2:48 am
1 stop10h 40m
$531
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Thu 11/26
12:15 pm-8:46 am
1 stop23h 31m
Guatemala City La Aurora
Fri 12/4
6:24 am-12:18 am
2 stops14h 54m
$531
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Santiago-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
SCL-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Guatemala City
How far ahead should I book a flight from Santiago to Guatemala City?
The best time to book flights from Santiago to Guatemala City is 9 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santiago to Guatemala City?
Currently, April is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $524). Flying from Santiago to Guatemala City in July is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Guatemala City?
Airfare is below average for this route at the moment.
Santiago to Guatemala City flights typically cost between $523 and $599 in October.The cheapest round-trip price found within the last 5 days was $508 on Avianca (Oct 13-Dec 28).
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated September 9, 2026.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.9
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.9
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Santiago to Guatemala City by cabin class
Find flights from Santiago to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Santiago and Guatemala City flights
Browse other Santiago and Guatemala City flight options. Last updated on September 9, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Santiago to Guatemala City
Discover the top 2 airlines that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$414 | Average$522 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$435 | Average$524 | FlexibilityNo cancel fee | On-time70% |