$250+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
Nov 20 — Nov 271
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to Guatemala City
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Cheapest flights from Santiago to Guatemala CityExplore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:10 am -
1 stop13h 55m
Wed 3/109:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$518
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:15 pm -
1 stop11h 40m
Wed 11/182:00 pm -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$519
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:10 am -
2 stops12h 20m
Thu 12/319:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$526
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:30 am -
1 stop12h 55m
Wed 12/29:20 am -
1 stop17h 25m
Deal found 10/21![Avianca logo]()
$528
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:10 am -
2 stops12h 20m
Thu 11/127:00 am -
2 stops15h 05m
Deal found 10/21![Avianca logo]()
$534
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:10 am -
2 stops12h 20m
Tue 11/247:00 am -
2 stops15h 05m
Deal found 10/20![Avianca logo]()
$535
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:07 am -
1 stop21h 46m
Tue 12/84:18 am -
1 stop12h 53m
Deal found 10/21![Copa Airlines logo]()
$541
This Avianca deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:10 am -
2 stops12h 20m
Mon 11/307:00 am -
2 stops15h 05m
Deal found 10/17![Avianca logo]()
$545
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
1 stop12h 55m
Tue 1/199:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$546
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/231:07 am -
1 stop21h 40m
Tue 12/296:24 am -
2 stops14h 59m
Deal found 10/21![Copa Airlines logo]()
$556
Best flights from Santiago to Guatemala CityDiscover carefully curated flight deals from Santiago to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from Santiago to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2111:58 pm -
2 stops24h 13m
Fri 4/25:50 am -
2 stops18h 51m
Deal found 10/20![Copa Airlines logo]()
$541
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:07 am -
1 stop21h 46m
Wed 12/96:24 am -
2 stops17h 24m
Deal found 10/21![Copa Airlines logo]()
$541
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:26 am -
1 stop10h 20m
Tue 11/246:19 am -
2 stops18h 19m
Deal found 10/19![Copa Airlines logo]()
$556
This Copa Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:15 pm -
2 stops12h 21m
Thu 11/126:19 am -
2 stops15h 05m
Deal found 10/17![Copa Airlines logo]()
$588
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:07 am -
1 stop20h 37m
Wed 1/136:24 am -
2 stops15h 04m
Deal found 10/19![Copa Airlines logo]()
$618
Last-minute flights from Santiago to Guatemala CityDiscover last-minute flight deals from Santiago to Guatemala City. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Guatemala City. Data last updated October 21, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:10 am -
2 stops12h 20m
Thu 11/127:00 am -
2 stops15h 05m
Deal found 10/21![Avianca logo]()
$534
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:15 pm -
1 stop11h 40m
Wed 11/182:00 pm -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$519
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:02 am -
1 stop11h 37m
Thu 11/121:08 pm -
1 stop10h 40m
Deal found 10/21![Copa Airlines logo]()
$556
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:15 pm -
2 stops12h 21m
Mon 11/236:19 am -
2 stops18h 19m
Deal found 10/21![Copa Airlines logo]()
$541
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:10 am -
2 stops12h 20m
Tue 11/247:00 am -
2 stops15h 05m
Deal found 10/20![Avianca logo]()
$535
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:10 am -
1 stop13h 55m
Wed 3/109:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$518
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:10 am -
2 stops12h 20m
Thu 12/319:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$526
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
1 stop12h 55m
Tue 1/199:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$546
This Avianca deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:10 am -
2 stops12h 20m
Mon 11/307:00 am -
2 stops15h 05m
Deal found 10/17![Avianca logo]()
$545
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:15 pm -
1 stop11h 40m
Fri 12/49:20 am -
1 stop12h 45m
Deal found 10/21![Avianca logo]()
$528
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:15 pm -
1 stop11h 40m
Wed 12/27:00 am -
2 stops15h 05m
Deal found 10/21![Avianca logo]()
$536
One-way flights from Santiago to Guatemala CitySearch for one-way flight options from Santiago to Guatemala City. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
Search for one-way flight options from Santiago to Guatemala City. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:30 am -
1 stop12h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$303
This Avianca deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:10 am -
2 stops12h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Avianca logo]()
$311
This Avianca deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:15 pm -
1 stop11h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Avianca logo]()
$312
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:20 pm -
1 stop23h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Copa Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:48 am -
1 stop31h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Copa Airlines logo]()
$317
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:26 am -
1 stop24h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Copa Airlines logo]()
$329
This Avianca deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/137:30 am -
1 stop12h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Avianca logo]()
$343
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:15 pm -
2 stops28h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:07 am -
2 stops41h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$383
Find flight deals from Santiago to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $518 (Avianca) |
One-way from | $303 (Avianca) |
Popular in | July |
Cheapest in | April |
Average price | $554 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 11/4
5:00 am-3:30 pm
1 stop13h 30m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$250
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Tue 11/10
2:10 am-1:05 pm
1 stop13h 55m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$303
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 11/4
7:30 am-5:25 pm
1 stop12h 55m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$303
Quickest round-trip
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Wed 10/28
2:10 am-11:30 am
2 stops12h 20m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$311
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Fri 11/6
2:10 am-11:30 am
2 stops12h 20m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$311
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Mon 3/15
1:16 am-9:11 pm
2 stops22h 55m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$314
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Mon 11/2
2:10 am-11:30 am
2 stops12h 20m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$321
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Mon 11/9
5:07 am-10:42 pm
1 stop20h 35m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$329
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Fri 1/22
5:13 am-11:06 pm
1 stop20h 53m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$329
SantiagoGuatemala City
SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora
SCLGUA
Santiago Arturo Merino Benitez
Fri 12/18
7:00 am-8:49 pm
2 stops40h 49m
Guatemala City La Aurora
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$408
Showing 1-10 of 17 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santiago-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
SCL-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Guatemala City
How far ahead should I book a flight from Santiago to Guatemala City?
The best time to book flights from Santiago to Guatemala City is 4 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santiago to Guatemala City?
Currently, April is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $524). Flying from Santiago to Guatemala City in July is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Guatemala City?
Airfare is typical for this route at the moment.
Santiago to Guatemala City flights typically cost between $517 and $626 in November.The cheapest round-trip price found within the last 5 days was $518 on Avianca (Nov 19-Dec 31).
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated October 21, 2026.
Get a feel of what it's like to fly with Copa Airlines from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Food
7.0
Entertainment
6.9
Comfort
7.5
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Boarding
7.8
Food
7.0
Entertainment
6.9
Comfort
7.5
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Santiago and Guatemala City flights
Browse other Santiago and Guatemala City flight options. Last updated on October 21, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Santiago to Guatemala City
Discover the top airline that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$398 | Average$580 | FlexibilityNo cancel fee | On-time70% |