To save up to 24% on this flight, we recommend booking at least 61 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Mesa to Guadalajara from $304 1-2 weeks out and tickets from $332 for flights departing within the next 72 hours.
March can be a great time to fly to Guadalajara from Mesa with a flight ticket averaging about $273. Cheapflights users have found deals in the month of March for as cheap as $182. The most expensive prices can be found in the month of December.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Guadalajara as you normally would.