How long is the flight from Columbus Airport to Greenville?

Airlines like Delta fly from Columbus Airport to Greenville in about 3h 59m. The time it takes to get you to your destination can typically vary by up to . There are 354 mi between Columbus Airport and Greenville.

What are the cheapest airlines flying from Columbus Airport to Greenville round-trip?

Currently priced at $164, American Airlines will fly you from Columbus Airport to Greenville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $196 and $217, respectively. These flights start at 50% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the most popular airlines that fly from Columbus Airport to Greenville?

The most popular airlines flying from Columbus Airport to Greenville are Delta, American Airlines and Southwest. Something to consider prior to booking your flight.

Most accurate provider : When it comes to deals on Columbus Airport-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Columbus Airport-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Columbus Airport-Greenville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Columbus Airport-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly into for flights to Greenville from Columbus?

Located just 10.4 mi from the city center, Greenville is the airport most travelers will use when flying to Greenville from Columbus. Booking flights from Columbus to Greenville (GSP) should be relatively easy as there are 0 daily inbound flights from Columbus from 4 different airlines.

Can I find deals for flights from Columbus to Greenville that include hotel bookings?

Yes. In addition to deals on Columbus to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Columbus to Greenville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Greenville.

Can I find deals for business class flights from Columbus to Greenville?

Yes. Cheapflights offers flight deals from Columbus to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$144+ Flights from Columbus Airport to Greenville

Q: How much does it cost to fly round-trip from Columbus Airport to Greenville?

Airfare is below average for this route at the moment. Columbus Airport to Greenville flights typically cost between $367 and $467 in February. The cheapest round-trip price found within the last 3 days was $231 on Multiple Airlines (Feb 25-Mar 1).

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Cheap flight deals from Columbus to Greenville

Cheapest flights from Columbus to Greenville
Explore the most affordable flight options available from Columbus to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Wed 12/313:45 pmCMH - GSP

1 stop4h 05mSouthwest

Wed 1/76:15 pmGSP - CMH

1 stop4h 00mSouthwest

Deal found 12/26

$555

Tue 12/303:05 pmCMH - GSP

1 stop7h 05mAmerican Airlines

Sun 1/48:07 pmGSP - CMH

1 stop6h 23mAmerican Airlines

Deal found 12/26

$637

Tue 12/307:45 pmCMH - GSP

2 stops15h 11mUnited Airlines

Sun 1/48:34 amGSP - CMH

1 stop6h 52mUnited Airlines

Deal found 12/26

$772

Best flights from Columbus to Greenville
Discover carefully curated flight deals from Columbus to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Sat 1/1712:54 pmCMH - GSP

1 stop3h 59mDelta

Mon 1/197:46 pmGSP - CMH

1 stop4h 18mDelta

Deal found 12/27

$247

Wed 2/2511:39 amCMH - GSP

1 stop28h 44mMultiple Airlines

Sun 3/15:13 pmGSP - CMH

2 stops17h 21mMultiple Airlines

Deal found 12/26

$254

Fri 2/612:30 pmCMH - GSP

2 stops7h 50mSouthwest

Tue 2/1011:15 amGSP - CMH

2 stops6h 15mSouthwest

Deal found 12/27

$302

Tue 2/2410:36 amCMH - GSP

1 stop3h 40mUnited Airlines

Thu 2/266:30 amGSP - CMH

1 stop6h 45mUnited Airlines

Deal found 12/25

$310

Thu 3/196:06 amCMH - GSP

1 stop6h 08mAmerican Airlines

Sun 3/225:20 amGSP - CMH

1 stop5h 40mAmerican Airlines

Deal found 12/27

$387

Thu 1/295:45 amCMH - GSP

1 stop11h 10mMultiple Airlines

Sun 2/15:45 pmGSP - CMH

2 stops17h 02mMultiple Airlines

Deal found 12/26

$266

Fri 2/64:33 pmCMH - GSP

1 stop5h 19mDelta

Tue 2/106:45 pmGSP - CMH

1 stop5h 18mDelta

Deal found 12/27

$281

Sun 1/1110:40 amCMH - GSP

1 stop22h 18mMultiple Airlines

Thu 1/154:43 pmGSP - CMH

1 stop16h 57mMultiple Airlines

Deal found 12/26

$271

Thu 1/299:05 amCMH - GSP

2 stops8h 30mSouthwest

Sun 2/18:20 amGSP - CMH

2 stops7h 30mSouthwest

Deal found 12/26

$316

Fri 1/236:06 amCMH - GSP

1 stop9h 53mMultiple Airlines

Sun 1/256:45 pmGSP - CMH

1 stop14h 55mMultiple Airlines

Deal found 12/27

$283

Sun 1/256:30 pmCMH - GSP

1 stop5h 18mUnited Airlines

Thu 1/296:35 amGSP - CMH

1 stop6h 47mUnited Airlines

Deal found 12/26

$356

Last-minute flights from Columbus to Greenville
Discover last-minute flight deals from Columbus to Greenville. Data last updated December 28, 2025 and is based on user searches.

Mon 1/511:14 amCMH - GSP

1 stop8h 54mMultiple Airlines

Thu 1/85:09 pmGSP - CMH

2 stops17h 39mMultiple Airlines

Deal found 12/26

$458

Sun 1/1110:40 amCMH - GSP

1 stop22h 18mMultiple Airlines

Thu 1/154:43 pmGSP - CMH

1 stop16h 57mMultiple Airlines

Deal found 12/26

$271

Sat 1/1712:54 pmCMH - GSP

1 stop3h 59mDelta

Mon 1/197:46 pmGSP - CMH

1 stop4h 18mDelta

Deal found 12/27

$247

Sat 1/174:13 pmCMH - GSP

2 stops7h 38mAmerican Airlines

Mon 1/196:00 amGSP - CMH

1 stop4h 42mAmerican Airlines

Deal found 12/27

$252

Fri 1/236:06 amCMH - GSP

1 stop9h 53mMultiple Airlines

Sun 1/256:45 pmGSP - CMH

1 stop14h 55mMultiple Airlines

Deal found 12/27

$283

Fri 1/238:50 amCMH - GSP

2 stops8h 45mSouthwest

Sun 1/258:20 amGSP - CMH

2 stops8h 00mSouthwest

Deal found 12/27

$377

Sun 1/256:30 pmCMH - GSP

1 stop5h 18mUnited Airlines

Thu 1/296:35 amGSP - CMH

1 stop6h 47mUnited Airlines

Deal found 12/26

$356

Thu 1/295:45 amCMH - GSP

1 stop11h 10mMultiple Airlines

Sun 2/15:45 pmGSP - CMH

2 stops17h 02mMultiple Airlines

Deal found 12/26

$266

Thu 1/299:05 amCMH - GSP

2 stops8h 30mSouthwest

Sun 2/18:20 amGSP - CMH

2 stops7h 30mSouthwest

Deal found 12/26

$316

One-way flights from Columbus to Greenville
Search for one-way flight options from Columbus to Greenville. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Fri 2/66:06 amCMH - GSP

1 stop13h 32mMultiple Airlines

Deal found 12/25

$144

Fri 1/236:00 amCMH - GSP

1 stop5h 03mDelta

Deal found 12/27

$184

Fri 1/239:05 amCMH - GSP

2 stops8h 30mSouthwest

Deal found 12/27

$189

Fri 2/64:27 pmCMH - GSP

2 stops27h 02mUnited Airlines

Deal found 12/25

$350

Find flight deals from Columbus to Greenville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$231 (Kiwi.com)
One-way from	$144 (Kiwi.com)
Popular in	May
Cheapest in	March
Average price	$377

Provider with most accurate pricing for Columbus-Greenville flight deals.

Search Deals

Provider most trusted by Cheapflights users for Columbus-Greenville flights.

Search Deals

From Columbus to Greenville

Search Deals

One-way flight from Columbus to Greenville

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($32 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Columbus Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Sat 1/17

12:54 pm-4:53 pm

1 stop3h 59m

Greenville

Mon 1/19

7:46 pm-12:04 am

1 stop4h 18m

$247

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Wed 2/25

11:39 am-4:23 pm

1 stop28h 44m

Greenville

Sun 3/1

5:13 pm-10:34 am

2 stops17h 21m

$254

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Thu 1/29

5:45 am-4:55 pm

1 stop11h 10m

Greenville

Sun 2/1

5:45 pm-10:47 am

2 stops17h 02m

$266

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Sun 1/11

10:40 am-8:58 am

1 stop22h 18m

Greenville

Thu 1/15

4:43 pm-9:40 am

1 stop16h 57m

$271

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Fri 2/6

4:33 pm-9:52 pm

1 stop5h 19m

Greenville

Tue 2/10

6:45 pm-12:03 am

1 stop5h 18m

$281

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Fri 1/23

6:06 am-3:59 pm

1 stop9h 53m

Greenville

Sun 1/25

6:45 pm-9:40 am

1 stop14h 55m

$283

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Fri 2/6

12:30 pm-8:20 pm

2 stops7h 50m

Greenville

Tue 2/10

11:15 am-5:30 pm

2 stops6h 15m

$302

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Tue 2/24

10:36 am-2:16 pm

1 stop3h 40m

Greenville

Thu 2/26

6:30 am-1:15 pm

1 stop6h 45m

$310

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Thu 1/29

9:05 am-5:35 pm

2 stops8h 30m

Greenville

Sun 2/1

8:20 am-3:50 pm

2 stops7h 30m

$316

ColumbusGreenville

CMH - GSP

CMHGSP

Columbus

Sun 1/25

6:30 pm-11:48 pm

1 stop5h 18m

Greenville

Thu 1/29

6:35 am-1:22 pm

1 stop6h 47m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 15 results

Compare providers for flights from Columbus to Greenville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Greenville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Columbus Airport-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Columbus Airport-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Columbus Airport-Greenville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Columbus Airport-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Columbus with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Greenville

What is the cheapest month to book a flight from Columbus Airport to Greenville?

Currently, October is the cheapest month in which you can book a flight from Columbus Airport to Greenville (average of $112). Flying from Columbus Airport to Greenville in December is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to GSP?

It’s optimal to fly from Columbus Airport to Greenville in the evening. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Columbus Airport to Greenville?

Reviews of airlines servicing Greenville

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Columbus Airport to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,256 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,019 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,113 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,073 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly into for flights to Greenville from Columbus?
Located just 10.4 mi from the city center, Greenville is the airport most travelers will use when flying to Greenville from Columbus. Booking flights from Columbus to Greenville (GSP) should be relatively easy as there are 0 daily inbound flights from Columbus from 4 different airlines.
How long is the flight from Columbus Airport to Greenville?
Airlines like Delta fly from Columbus Airport to Greenville in about 3h 59m. The time it takes to get you to your destination can typically vary by up to . There are 354 mi between Columbus Airport and Greenville.
What are the cheapest airlines flying from Columbus Airport to Greenville round-trip?
Currently priced at $164, American Airlines will fly you from Columbus Airport to Greenville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $196 and $217, respectively. These flights start at 50% lower than the current average price 3 months from now.
Can I find deals for flights from Columbus to Greenville that include hotel bookings?
Yes. In addition to deals on Columbus to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Columbus to Greenville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Greenville.
Can I find deals for business class flights from Columbus to Greenville?
Yes. Cheapflights offers flight deals from Columbus to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Columbus Airport to Greenville?
Currently, October is the cheapest month in which you can book a flight from Columbus Airport to Greenville (average of $112). Flying from Columbus Airport to Greenville in December is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Simpsonville

Duncan

Greer

Seneca

Anderson

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Top 4 airlines flying from Columbus to Greenville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$164	Average$351	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$196	Average$335	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$217	Average$318	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$228	Average$330	FlexibilityNo cancel fee	On-time63%

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$144+ Cheap flights from Columbus (CMH) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Columbus to Greenville with Cheapflights

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Cheap flight deals from Columbus to Greenville

Cheapest flights from Columbus to GreenvilleExplore the most affordable flight options available from Columbus to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Columbus to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Columbus to Greenville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Columbus Airport to Greenville that are best for you.

Compare providers for flights from Columbus to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Greenville in December.

Best time to book a flight from Columbus to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Columbus with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Greenville

What is the cheapest month to book a flight from Columbus Airport to Greenville?

What is the cheapest time of day to fly from CMH to GSP?

How much does it cost to fly round-trip from Columbus Airport to Greenville?

Reviews of airlines servicing Greenville

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Columbus Airport to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Greenville from Columbus?

How long is the flight from Columbus Airport to Greenville?

What are the cheapest airlines flying from Columbus Airport to Greenville round-trip?

Can I find deals for flights from Columbus to Greenville that include hotel bookings?

How can I find direct flights from Columbus to Greenville?

Can I find deals for business class flights from Columbus to Greenville?

What is the cheapest month to book a flight from Columbus Airport to Greenville?

Traveling to a place near Greenville?

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Alternative routes for Columbus to Greenville

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Top 4 airlines flying from Columbus to Greenville

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Cheapest flights from Columbus to Greenville
Explore the most affordable flight options available from Columbus to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.