What are the cheapest airlines flying from New Orleans to Greenville round-trip?

According to our current data, Delta ($236), and American Airlines ($286) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 42% less than the average price by searching for these airlines.

What is the cheapest day to fly from New Orleans to Greenville?

Travelers seeking maximum savings on their New Orleans to Greenville flight should consider departing on Tuesday mornings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest day to fly round-trip from New Orleans to Greenville?

Users have found that leaving on a Monday can be a cost-effective option. It’s possible to save up to 65% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from New Orleans to Greenville?

April can be a great time to fly to Greenville from New Orleans with a flight ticket averaging about $414. Cheapflights users have found deals in the month of April for as cheap as $281. The most expensive prices can be found in the month of December.

Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from New Orleans to Greenville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.

Can I find deals for business class flights from New Orleans to Greenville?

Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$100+ Flights from New Orleans to Greenville

Q: How much does it cost to fly round-trip from New Orleans to Greenville?

Airfare is below average for this route at the moment. New Orleans to Greenville flights typically cost between $306 and $496 in October. The cheapest round-trip price found within the last 3 days was $243 on Multiple Airlines (Oct 22-Oct 26).

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Cheap flight deals from New Orleans to Greenville

Round-trip from	$243 (Kiwi.com)
One-way from	$100 (Mytrip)
Popular in	December
Cheapest in	April
Average price	$376

From New Orleans Louis Armstrong to Greenville

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One-way flight from New Orleans Louis Armstrong to Greenville

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Highest demand for flights based on searches. 10% potential increase in price ($46 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Wed 10/2212:20 pmMSY - GSP

1 stop25h 27mMultiple Airlines

Sun 10/263:37 pmGSP - MSY

1 stop9h 01mMultiple Airlines

Deal found 8/15

$243

Fri 9/55:03 pmMSY - GSP

1 stop5h 31mDelta

Sun 9/75:30 amGSP - MSY

1 stop5h 20mDelta

Deal found 8/13

$281

Thu 9/187:20 pmMSY - GSP

1 stop17h 37mMultiple Airlines

Mon 9/2212:17 pmGSP - MSY

1 stop8h 27mMultiple Airlines

Deal found 8/15

$285

Fri 9/58:05 amMSY - GSP

2 stops9h 00mSouthwest

Sun 9/77:55 pmGSP - MSY

1 stop4h 25mSouthwest

Deal found 8/13

$286

Sat 8/303:06 pmMSY - GSP

1 stop5h 05mDelta

Sun 8/315:30 amGSP - MSY

1 stop4h 30mDelta

Deal found 8/15

$287

Sun 10/265:10 amMSY - GSP

2 stops7h 00mSouthwest

Tue 10/283:00 pmGSP - MSY

1 stop7h 15mSouthwest

Deal found 8/14

$335

Thu 10/91:30 pmMSY - GSP

1 stop6h 55mSouthwest

Sat 10/118:00 amGSP - MSY

2 stops8h 55mSouthwest

Deal found 8/15

$352

Best flights from New Orleans to Greenville
Discover carefully curated flight deals from New Orleans to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2025.

Wed 10/2212:20 pmMSY - GSP

1 stop25h 27mMultiple Airlines

Sun 10/263:37 pmGSP - MSY

1 stop9h 01mMultiple Airlines

Deal found 8/15

$243

Fri 9/55:03 pmMSY - GSP

1 stop5h 31mDelta

Sun 9/75:30 amGSP - MSY

1 stop5h 20mDelta

Deal found 8/13

$281

Fri 9/58:05 amMSY - GSP

2 stops9h 00mSouthwest

Sun 9/77:55 pmGSP - MSY

1 stop4h 25mSouthwest

Deal found 8/13

$286

Thu 10/94:23 pmMSY - GSP

1 stop6h 28mAmerican Airlines

Sat 10/114:46 pmGSP - MSY

1 stop5h 49mAmerican Airlines

Deal found 8/15

$311

Fri 9/265:13 pmMSY - GSP

1 stop5h 39mDelta

Sun 9/285:30 amGSP - MSY

1 stop3h 30mDelta

Deal found 8/14

$281

Thu 9/187:20 pmMSY - GSP

1 stop17h 37mMultiple Airlines

Mon 9/2212:17 pmGSP - MSY

1 stop8h 27mMultiple Airlines

Deal found 8/15

$285

Sat 8/303:06 pmMSY - GSP

1 stop5h 05mDelta

Sun 8/315:30 amGSP - MSY

1 stop4h 30mDelta

Deal found 8/15

$287

Sun 10/265:10 amMSY - GSP

2 stops7h 00mSouthwest

Tue 10/283:00 pmGSP - MSY

1 stop7h 15mSouthwest

Deal found 8/14

$335

Last-minute flights from New Orleans to Greenville
Discover last-minute flight deals from New Orleans to Greenville. Data last updated August 16, 2025 and is based on user searches.

Fri 8/224:12 pmMSY - GSP

1 stop5h 18mAmerican Airlines

Fri 8/296:05 pmGSP - MSY

1 stop6h 50mAmerican Airlines

Deal found 8/15

$467

Fri 8/2210:40 amMSY - GSP

2 stops9h 20mSouthwest

Fri 8/2910:45 amGSP - MSY

1 stop4h 35mSouthwest

Deal found 8/15

$532

Sat 8/303:06 pmMSY - GSP

1 stop5h 05mDelta

Sun 8/315:30 amGSP - MSY

1 stop4h 30mDelta

Deal found 8/15

$287

Thu 9/43:06 pmMSY - GSP

1 stop5h 05mDelta

Mon 9/85:30 amGSP - MSY

1 stop5h 20mDelta

Deal found 8/15

$387

Thu 9/410:15 amMSY - GSP

2 stops7h 37mUnited Airlines

Mon 9/86:02 amGSP - MSY

1 stop5h 15mUnited Airlines

Deal found 8/15

$462

Fri 9/55:03 pmMSY - GSP

1 stop5h 31mDelta

Sun 9/75:30 amGSP - MSY

1 stop5h 20mDelta

Deal found 8/13

$281

Fri 9/58:05 amMSY - GSP

2 stops9h 00mSouthwest

Sun 9/77:55 pmGSP - MSY

1 stop4h 25mSouthwest

Deal found 8/13

$286

Thu 9/187:20 pmMSY - GSP

1 stop17h 37mMultiple Airlines

Mon 9/2212:17 pmGSP - MSY

1 stop8h 27mMultiple Airlines

Deal found 8/15

$285

Thu 9/189:05 amMSY - GSP

1 stop3h 23mDelta

Mon 9/226:13 pmGSP - MSY

1 stop6h 16mDelta

Deal found 8/15

$442

Fri 9/2610:00 amMSY - GSP

1 stop10h 00mSouthwest

Sun 9/287:15 amGSP - MSY

2 stops8h 50mSouthwest

Deal found 8/14

$365

One-way flights from New Orleans to Greenville
Search for one-way flight options from New Orleans to Greenville. Find affordable one-way fares based on user searches. Data last updated August 16, 2025.

Sun 10/56:00 amMSY - GSP

1 stop7h 54mMultiple Airlines

Deal found 8/15

$100

Sat 10/186:00 amMSY - GSP

1 stop7h 48mMultiple Airlines

Deal found 8/15

$103

Sun 10/196:00 amMSY - GSP

1 stop7h 52mMultiple Airlines

Deal found 8/15

$106

Thu 10/236:00 amMSY - GSP

1 stop7h 47mMultiple Airlines

Deal found 8/15

$109

Wed 11/195:10 amMSY - GSP

1 stop9h 16mMultiple Airlines

Deal found 8/14

$110

Tue 9/169:28 pmMSY - GSP

2 stops36h 00mMultiple Airlines

Deal found 8/15

$111

Sat 10/42:38 pmMSY - GSP

1 stop23h 16mMultiple Airlines

Deal found 8/15

$112

Fri 10/179:42 pmMSY - GSP

1 stop16h 06mMultiple Airlines

Deal found 8/15

$114

Thu 10/211:01 amMSY - GSP

1 stop7h 15mAvelo Airlines

Deal found 8/14

$115

Thu 12/46:35 pmMSY - GSP

1 stop25h 14mMultiple Airlines

Deal found 8/15

$116

Tue 9/166:25 amMSY - GSP

1 stop6h 03mDelta

Deal found 8/14

$117

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 10/22

12:20 pm-2:47 pm

1 stop25h 27m

Greenville

Sun 10/26

3:37 pm-11:38 pm

1 stop9h 01m

$243

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 9/5

5:03 pm-11:34 pm

1 stop5h 31m

Greenville

Sun 9/7

5:30 am-9:50 am

1 stop5h 20m

$281

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 9/26

5:13 pm-11:52 pm

1 stop5h 39m

Greenville

Sun 9/28

5:30 am-8:00 am

1 stop3h 30m

$281

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 9/18

7:20 pm-1:57 pm

1 stop17h 37m

Greenville

Mon 9/22

12:17 pm-7:44 pm

1 stop8h 27m

$285

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 9/5

8:05 am-6:05 pm

2 stops9h 00m

Greenville

Sun 9/7

7:55 pm-11:20 pm

1 stop4h 25m

$286

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sat 8/30

3:06 pm-9:11 pm

1 stop5h 05m

Greenville

Sun 8/31

5:30 am-9:00 am

1 stop4h 30m

$287

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 10/9

4:23 pm-11:51 pm

1 stop6h 28m

Greenville

Sat 10/11

4:46 pm-9:35 pm

1 stop5h 49m

$311

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sun 10/26

5:10 am-1:10 pm

2 stops7h 00m

Greenville

Tue 10/28

3:00 pm-9:15 pm

1 stop7h 15m

$335

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sat 10/18

6:00 am-2:48 pm

1 stop7h 48m

$103

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sun 10/19

6:00 am-2:52 pm

1 stop7h 52m

$106

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 16 results

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

Currently, January is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $329). Flying from New Orleans to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to GSP?

It’s optimal to fly from New Orleans to Greenville in the morning. By choosing this option you can save up to 12% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from New Orleans to Greenville?

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,985 reviews

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from New Orleans to Greenville round-trip?
According to our current data, Delta ($236), and American Airlines ($286) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 42% less than the average price by searching for these airlines.
Can I find deals for flights from New Orleans to Greenville that include hotel bookings?
Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from New Orleans to Greenville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.
Can I find deals for business class flights from New Orleans to Greenville?
Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from New Orleans to Greenville?
Currently, January is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $329). Flying from New Orleans to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to Greenville

Top 2 airlines flying from New Orleans to Greenville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$236	Average$432	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$286	Average$395	FlexibilityNo cancel fee	On-time71%

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$100+ Cheap flights from New Orleans to Greenville (MSY - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from New Orleans to Greenville with Cheapflights

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Cheap flight deals from New Orleans to Greenville

Round-trip from

One-way from

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Cheapest in

Average price

Find flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to GreenvilleExplore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

What is the cheapest time of day to fly from MSY to GSP?

Find hourly flight availability from New Orleans to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

How much does it cost to fly round-trip from New Orleans to Greenville?

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from New Orleans to Greenville round-trip?

Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

How can I find direct flights from New Orleans to Greenville?

Can I find deals for business class flights from New Orleans to Greenville?

What is the cheapest month to book a flight from New Orleans to Greenville?

Traveling to a place near Greenville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for New Orleans to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from New Orleans to Greenville

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Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.