How long is the flight from New Orleans to Greenville?

American Airlines and United Airlines can get you from New Orleans to Greenville in just under 5h 49m. Your travel time can differ by up to 3h 45m. The distance between New Orleans and Greenville is about 578 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from New Orleans to Greenville round-trip?

According to our current data, Delta ($140), and American Airlines ($295) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 66% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from New Orleans to Greenville one-way?

To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $118. Southwest flights start at $118 while deals on American Airlines start at $148 one-way.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Most accurate provider : When it comes to deals on New Orleans-Greenville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Greenville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Greenville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on New Orleans-Greenville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from New Orleans to Greenville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.

Can I find deals for business class flights from New Orleans to Greenville?

Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$99+ Flights from New Orleans to Greenville

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Cheap flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/316:40 amMSY - GSP

1 stop8h 15mMultiple Airlines

Sun 1/45:17 pmGSP - MSY

1 stop25h 33mMultiple Airlines

Deal found 12/16

$273

Wed 12/312:14 pmMSY - GSP

3 stops23h 01mUnited Airlines

Sun 1/45:36 pmGSP - MSY

1 stop5h 53mUnited Airlines

Deal found 12/16

$544

Best flights from New Orleans to Greenville
Discover carefully curated flight deals from New Orleans to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Fri 1/97:00 amMSY - GSP

1 stop7h 59mMultiple Airlines

Mon 1/124:39 pmGSP - MSY

2 stops29h 50mMultiple Airlines

Deal found 12/16

$247

Tue 1/137:52 amMSY - GSP

1 stop9h 34mAmerican Airlines

Tue 1/207:16 amGSP - MSY

1 stop7h 36mAmerican Airlines

Deal found 12/17

$247

Tue 1/2712:40 pmMSY - GSP

1 stop5h 49mUnited Airlines

Sat 1/316:49 amGSP - MSY

1 stop5h 03mUnited Airlines

Deal found 12/16

$294

Tue 1/271:55 pmMSY - GSP

1 stop4h 55mSouthwest

Sat 1/317:45 amGSP - MSY

2 stops10h 35mSouthwest

Deal found 12/16

$299

Fri 5/18:00 amMSY - GSP

1 stop10h 38mBreeze Airways

Sun 5/32:12 pmGSP - MSY

1 stop3h 58mBreeze Airways

Deal found 12/17

$319

Wed 12/316:40 amMSY - GSP

1 stop8h 15mMultiple Airlines

Sun 1/45:17 pmGSP - MSY

1 stop25h 33mMultiple Airlines

Deal found 12/16

$273

Fri 1/166:23 amMSY - GSP

1 stop4h 01mAmerican Airlines

Fri 1/166:56 pmGSP - MSY

1 stop6h 00mAmerican Airlines

Deal found 12/16

$303

Thu 1/153:43 pmMSY - GSP

2 stops16h 15mMultiple Airlines

Fri 1/169:49 pmGSP - MSY

3 stops22h 52mMultiple Airlines

Deal found 12/16

$285

Tue 1/139:05 amMSY - GSP

1 stop5h 30mUnited Airlines

Tue 1/2010:00 amGSP - MSY

2 stops9h 08mUnited Airlines

Deal found 12/17

$348

Last-minute flights from New Orleans to Greenville
Discover last-minute flight deals from New Orleans to Greenville. Data last updated December 18, 2025 and is based on user searches.

Wed 12/316:40 amMSY - GSP

1 stop8h 15mMultiple Airlines

Sun 1/45:17 pmGSP - MSY

1 stop25h 33mMultiple Airlines

Deal found 12/16

$273

Fri 1/97:00 amMSY - GSP

1 stop7h 59mMultiple Airlines

Mon 1/124:39 pmGSP - MSY

1 stop7h 19mMultiple Airlines

Deal found 12/16

$217

Thu 1/156:05 amMSY - GSP

1 stop8h 48mMultiple Airlines

Fri 1/169:48 amGSP - MSY

1 stop23h 33mMultiple Airlines

Deal found 12/16

$216

Fri 1/166:23 amMSY - GSP

1 stop4h 01mAmerican Airlines

Fri 1/166:56 pmGSP - MSY

1 stop6h 00mAmerican Airlines

Deal found 12/16

$303

Tue 1/2712:40 pmMSY - GSP

1 stop5h 49mUnited Airlines

Sat 1/316:49 amGSP - MSY

1 stop5h 03mUnited Airlines

Deal found 12/16

$294

Tue 1/271:55 pmMSY - GSP

1 stop4h 55mSouthwest

Sat 1/317:45 amGSP - MSY

2 stops10h 35mSouthwest

Deal found 12/16

$299

One-way flights from New Orleans to Greenville
Search for one-way flight options from New Orleans to Greenville. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Wed 12/316:40 amMSY - GSP

1 stop8h 15mMultiple Airlines

Deal found 12/17

$99

Tue 12/305:00 pmMSY - GSP

2 stops21h 55mMultiple Airlines

Deal found 12/16

$134

Sun 4/58:15 amMSY - GSP

1 stop3h 57mBreeze Airways

Deal found 12/17

$138

Mon 12/296:55 pmMSY - GSP

1 stop24h 45mMultiple Airlines

Deal found 12/15

$160

Mon 4/62:29 pmMSY - GSP

1 stop3h 32mDelta

Deal found 12/17

$184

Mon 4/63:00 pmMSY - GSP

2 stops6h 45mSouthwest

Deal found 12/17

$189

Find flight deals from New Orleans to Greenville

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$216 (Kiwi.com)
One-way from	$99 (Kiwi.com)
Popular in	September
Cheapest in	April
Average price	$471

Provider with most accurate pricing for New Orleans Louis Armstrong-Greenville flight deals.

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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Greenville flights.

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From New Orleans Louis Armstrong to Greenville

Search Deals

One-way flight from New Orleans Louis Armstrong to Greenville

Search Deals

High demand for flights, 4% potential price rise

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 1/9

7:00 am-3:59 pm

1 stop7h 59m

Greenville

Mon 1/12

4:39 pm-9:29 pm

2 stops29h 50m

$247

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/13

7:52 am-6:26 pm

1 stop9h 34m

Greenville

Tue 1/20

7:16 am-1:52 pm

1 stop7h 36m

$247

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 12/31

6:40 am-3:55 pm

1 stop8h 15m

Greenville

Sun 1/4

5:17 pm-5:50 pm

1 stop25h 33m

$273

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 1/15

3:43 pm-8:58 am

2 stops16h 15m

Greenville

Fri 1/16

9:49 pm-7:41 pm

3 stops22h 52m

$285

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/27

12:40 pm-7:29 pm

1 stop5h 49m

Greenville

Sat 1/31

6:49 am-10:52 am

1 stop5h 03m

$294

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/27

1:55 pm-7:50 pm

1 stop4h 55m

Greenville

Sat 1/31

7:45 am-5:20 pm

2 stops10h 35m

$299

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 1/16

6:23 am-11:24 am

1 stop4h 01m

Greenville

Fri 1/16

6:56 pm-11:56 pm

1 stop6h 00m

$303

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 5/1

8:00 am-7:38 pm

1 stop10h 38m

Greenville

Sun 5/3

2:12 pm-5:10 pm

1 stop3h 58m

$319

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/13

9:05 am-3:35 pm

1 stop5h 30m

Greenville

Tue 1/20

10:00 am-6:08 pm

2 stops9h 08m

$348

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 12/30

5:00 pm-3:55 pm

2 stops21h 55m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 16 results

Compare providers for flights from New Orleans to Greenville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Greenville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on New Orleans-Greenville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Greenville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Greenville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on New Orleans-Greenville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

Currently, February is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $78). Flying from New Orleans to Greenville in December is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to GSP?

It’s optimal to fly from New Orleans to Greenville in the morning. By choosing this option you can save up to 58% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,005 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,054 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from New Orleans to Greenville?
American Airlines and United Airlines can get you from New Orleans to Greenville in just under 5h 49m. Your travel time can differ by up to 3h 45m. The distance between New Orleans and Greenville is about 578 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from New Orleans to Greenville round-trip?
According to our current data, Delta ($140), and American Airlines ($295) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 66% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from New Orleans to Greenville one-way?
To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $118. Southwest flights start at $118 while deals on American Airlines start at $148 one-way.
Can I find deals for flights from New Orleans to Greenville that include hotel bookings?
Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from New Orleans to Greenville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.
Can I find deals for business class flights from New Orleans to Greenville?
Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from New Orleans to Greenville?
Currently, February is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $78). Flying from New Orleans to Greenville in December is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Simpsonville

Duncan

Greer

Seneca

Anderson

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Top 2 airlines flying from New Orleans to Greenville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$252	Average$404	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$295	Average$399	FlexibilityNo cancel fee	On-time71%

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$99+ Cheap flights from New Orleans to Greenville (MSY - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from New Orleans to Greenville with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to GreenvilleExplore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from New Orleans to Greenville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Compare providers for flights from New Orleans to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Greenville in December.

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

What is the cheapest time of day to fly from MSY to GSP?

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from New Orleans to Greenville?

What are the cheapest airlines flying from New Orleans to Greenville round-trip?

What are the cheapest airlines to fly from New Orleans to Greenville one-way?

Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

How can I find direct flights from New Orleans to Greenville?

Can I find deals for business class flights from New Orleans to Greenville?

What is the cheapest month to book a flight from New Orleans to Greenville?

Traveling to a place near Greenville?

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Alternative routes for New Orleans to Greenville

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Top 2 airlines flying from New Orleans to Greenville

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Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.