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$105+ Cheap flights from New Orleans to Greenville (MSY - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — GSP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from New Orleans to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from New Orleans (MSY) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$250
(Kiwi.com)

One-way from

$105
(United Airlines)

Popular in

December

Cheapest in

April

Average price

$504

Good round-trip deal

$269 or less
From New Orleans Louis Armstrong to Greenville
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One-way flight from New Orleans Louis Armstrong to Greenville
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Highest demand for flights based on searches. 8% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from New Orleans Louis Armstrong to Greenville.
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Find flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/43:37 pmMSY - GSP
1 stop5h 23mAmerican Airlines
Sat 10/114:46 pmGSP - MSY
1 stop5h 49mAmerican Airlines
Deal found 9/13$253
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/241:19 pmMSY - GSP
1 stop5h 04mMultiple Airlines
Mon 10/278:03 pmGSP - MSY
1 stop27h 34mMultiple Airlines
Deal found 9/14$283
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/289:07 pmMSY - GSP
2 stops20h 39mMultiple Airlines
Thu 10/24:47 pmGSP - MSY
1 stop27h 57mMultiple Airlines
Deal found 9/13$286
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:00 amMSY - GSP
1 stop5h 36mUnited Airlines
Tue 10/145:00 pmGSP - MSY
1 stop7h 15mUnited Airlines
Deal found 9/13$287
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:20 amMSY - GSP
1 stop7h 25mSouthwest
Wed 10/296:05 amGSP - MSY
2 stops6h 55mSouthwest
Deal found 9/15$292
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:06 pmMSY - GSP
1 stop4h 53mAmerican Airlines
Mon 11/1010:33 amGSP - MSY
1 stop7h 31mAmerican Airlines
Deal found 9/14$297
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:45 pmMSY - GSP
1 stop4h 06mAmerican Airlines
Mon 10/135:00 amGSP - MSY
1 stop4h 40mAmerican Airlines
Deal found 9/13$298
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:38 amMSY - GSP
2 stops8h 36mMultiple Airlines
Mon 11/108:03 pmGSP - MSY
1 stop24h 40mMultiple Airlines
Deal found 9/14$301
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:20 amMSY - GSP
1 stop5h 26mAmerican Airlines
Wed 10/84:46 pmGSP - MSY
1 stop5h 49mAmerican Airlines
Deal found 9/13$352
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1112:15 pmMSY - GSP
1 stop5h 00mSouthwest
Tue 10/146:05 amGSP - MSY
2 stops7h 35mSouthwest
Deal found 9/13$357

Cheapflights Fare Finder

 
Customize your flight search to find flights from New Orleans to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Fly from

New Orleans

Fly to

Greenville

Route

Depart

Return

Price

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 2/19

8:15 am-1:12 pm

1 stop3h 57m

Greenville

Sun 2/22

5:17 pm-8:05 am

1 stop15h 48m

$250

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 10/2

7:20 pm-2:50 pm

1 stop18h 30m

Greenville

Mon 10/6

8:03 pm-10:37 pm

1 stop27h 34m

$268

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 10/24

1:19 pm-7:23 pm

1 stop5h 04m

Greenville

Mon 10/27

8:03 pm-10:37 pm

1 stop27h 34m

$283

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sat 10/25

6:20 am-2:45 pm

1 stop7h 25m

Greenville

Wed 10/29

7:05 pm-10:30 pm

1 stop4h 25m

$287

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 10/29

6:20 am-12:50 pm

1 stop5h 30m

Greenville

Sat 11/1

1:32 pm-4:47 pm

1 stop4h 15m

$287

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 11/6

6:06 pm-11:59 pm

1 stop4h 53m

Greenville

Mon 11/10

10:33 am-5:04 pm

1 stop7h 31m

$297

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 11/6

11:38 am-9:14 pm

2 stops8h 36m

Greenville

Mon 11/10

8:03 pm-7:43 pm

1 stop24h 40m

$301

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 10/30

8:50 pm-7:23 pm

1 stop21h 33m

Greenville

Thu 11/6

10:33 am-4:03 pm

2 stops30h 30m

$308

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 10/16

10:17 pm-2:48 pm

2 stops39h 31m

$129

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 10/23

4:40 pm-7:23 pm

1 stop25h 43m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 19 results
1
2

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

Currently, August is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $321). Flying from New Orleans to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to GSP?

Find hourly flight availability from New Orleans to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

It’s optimal to fly from New Orleans to Greenville in the morning. By choosing this option you can save up to 49% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New Orleans to Greenville?

    Southwest and Delta can get you from New Orleans to Greenville in just under 5h 30m. Your travel time can differ by up to 1h 55m. The distance between New Orleans and Greenville is about 578 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from New Orleans to Greenville round-trip?

    According to our current data, Delta ($252), and American Airlines ($296) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 40% less than the average price by searching for these airlines.

  • What are the most reliable airlines from New Orleans to Greenville?

    Before booking your flight to Greenville from New Orleans, check out the most reliable airlines to get you to your destination on time: American Airlines (100%), Delta (100%), Southwest( 0%).

  • What are the cheapest flights from New Orleans to Greenville?

    While on average a flight from New Orleans to Greenville is generally $500, our data shows the cheapest flight currently is $269. When looking at the most popular route, (New Orleans Louis Armstrong - Greenville), you can expect to pay $250 for that flight.

  • Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

    Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from New Orleans to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.

  • Can I find deals for business class flights from New Orleans to Greenville?

    Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New Orleans to Greenville?

    Currently, August is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $321). Flying from New Orleans to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Alternative routes for New Orleans to Greenville

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Top 2 airlines flying from New Orleans to Greenville

Discover the top 2 airlines that operate flights from New Orleans to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$404FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$306Average$415FlexibilityNo cancel feeOn-time71%

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