Grand Cayman

$123+ Cheap flights from St. Louis (STL) to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Dec 31 — Jan 71
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Find flight deals from St. Louis to Grand Cayman

Cheapest flights from St. Louis to Grand Cayman
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 1, 2025.

This Delta deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amSTL - GCM
1 stop5h 36mDelta
Wed 12/313:42 pmGCM - STL
1 stop8h 56mDelta
Deal found 11/28$367
This American Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:30 amSTL - GCM
2 stops29h 35mAmerican Airlines
Wed 12/3112:55 pmGCM - STL
1 stop7h 35mAmerican Airlines
Deal found 11/28$442
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:30 amSTL - GCM
1 stop6h 15mUnited Airlines
Tue 12/302:50 pmGCM - STL
1 stop26h 37mUnited Airlines
Deal found 12/1$477
This United Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:10 pmSTL - GCM
1 stop21h 35mUnited Airlines
Wed 12/312:50 pmGCM - STL
1 stop8h 53mUnited Airlines
Deal found 11/28$479
This Delta deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amSTL - GCM
1 stop5h 36mDelta
Thu 1/11:52 pmGCM - STL
1 stop6h 12mDelta
Deal found 11/28$486

Cheap flight deals from St. Louis to Grand Cayman

Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated December 1, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$355
(Air Canada)

One-way from

$123
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$661
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
From Lambert-St Louis to Grand Cayman
One-way flight from Lambert-St Louis to Grand Cayman
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.

Fly from

St. Louis

Fly to

Grand Cayman

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 12/30

6:00 am-12:36 pm

1 stop5h 36m

George Town Owen Roberts Intl

Wed 12/31

3:42 pm-11:38 pm

1 stop8h 56m

$367

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 12/29

6:35 pm-1:45 pm

1 stop18h 10m

George Town Owen Roberts Intl

Wed 12/31

5:45 pm-9:49 am

1 stop17h 04m

$477

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 12/30

6:00 am-4:00 pm

1 stop9h 00m

George Town Owen Roberts Intl

Wed 12/31

5:10 pm-2:26 pm

2 stops22h 16m

$479

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 12/31

7:00 am-2:27 pm

1 stop6h 27m

George Town Owen Roberts Intl

Thu 1/1

3:42 pm-11:38 pm

1 stop8h 56m

$486

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 12/30

7:00 am-2:27 pm

1 stop6h 27m

George Town Owen Roberts Intl

Thu 1/1

1:52 pm-7:04 pm

1 stop6h 12m

$486

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/3

5:55 am-12:40 pm

1 stop5h 45m

George Town Owen Roberts Intl

Wed 1/7

2:05 pm-11:39 pm

1 stop10h 34m

$495

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 12/19

6:00 am-4:00 pm

1 stop9h 00m

George Town Owen Roberts Intl

Tue 12/23

5:45 pm-9:49 am

1 stop17h 04m

$516

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 1/14

8:32 pm-1:53 pm

2 stops16h 21m

$123

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 12/7

6:15 am-4:30 pm

1 stop9h 15m

$136

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 3/9

11:22 am-7:15 pm

1 stop7h 53m

$136

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/30

Showing 1-10 of 14 results
1
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Best time to book a flight from St. Louis to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Grand Cayman

What is the cheapest month to book a flight from St. Louis to Grand Cayman?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $267). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated December 1, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from St. Louis to Grand Cayman?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Grand Cayman. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How long is the flight from St. Louis to Grand Cayman?

    For as low as $367, Delta can have you in Grand Cayman from St. Louis in 5h 36m. Airlines will cover a distance of 1448 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from St. Louis to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on St. Louis to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Grand Cayman.

  • Can I find deals for business class flights from St. Louis to Grand Cayman?

    Yes. Cheapflights offers flight deals from St. Louis to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Grand Cayman?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $267). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from St. Louis to Grand Cayman

Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$266Average$613FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$606FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$429Average$581FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$469Average$724FlexibilityNo cancel feeOn-time69%

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