$120+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Feb 26 — Mar 51
1 adult, Economy
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Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.
This Air Canada deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:05 pm
STL
- GCM
1 stop19h 05m
Air Canada
Sat 5/212:25 pm
GCM
- STL
1 stop23h 41m
Air Canada
Deal found 1/26![Air Canada logo]()
$382
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
STL
- GCM
1 stop5h 29m
Delta
Sat 3/71:54 pm
GCM
- STL
1 stop10h 42m
Delta
Deal found 1/25![Delta logo]()
$392
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:54 pm
STL
- GCM
1 stop16h 41m
American Airlines
Mon 4/202:10 pm
GCM
- STL
2 stops18h 47m
American Airlines
Deal found 1/24![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:00 am
STL
- GCM
2 stops11h 15m
American Airlines
Sun 3/82:44 pm
GCM
- STL
1 stop9h 00m
American Airlines
Deal found 1/25![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Sat 2/212:50 pm
GCM
- STL
1 stop7h 15m
United Airlines
Deal found 1/25![United Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
STL
- GCM
1 stop6h 30m
United Airlines
Mon 4/271:50 pm
GCM
- STL
1 stop18h 45m
United Airlines
Deal found 1/26![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
STL
- GCM
1 stop5h 29m
Delta
Sat 3/712:25 pm
GCM
- STL
1 stop8h 41m
Delta
Deal found 1/25![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:54 pm
STL
- GCM
2 stops18h 17m
American Airlines
Mon 4/272:10 pm
GCM
- STL
2 stops19h 33m
American Airlines
Deal found 1/26![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:53 pm
STL
- GCM
1 stop16h 39m
American Airlines
Sat 5/23:13 pm
GCM
- STL
1 stop7h 51m
American Airlines
Deal found 1/27![American Airlines logo]()
$438
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated January 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $382 (Air Canada) |
One-way from | $120 (Delta) |
Popular in | March |
Cheapest in | September |
Average price | $571 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
St. Louis
Fly to
Grand Cayman
Route
Depart
Return
Price
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 4/13
4:05 pm-11:10 am
1 stop19h 05m
George Town Owen Roberts Intl
Mon 4/20
12:30 pm-3:24 pm
1 stop26h 54m
$382
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 4/18
4:05 pm-11:10 am
1 stop19h 05m
George Town Owen Roberts Intl
Sat 5/2
12:25 pm-8:04 pm
1 stop7h 39m
$382
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 4/13
6:54 pm-11:35 am
1 stop16h 41m
George Town Owen Roberts Intl
Mon 4/20
2:10 pm-8:57 am
2 stops18h 47m
$397
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 3/4
8:00 am-8:15 pm
2 stops11h 15m
George Town Owen Roberts Intl
Sun 3/8
2:44 pm-11:44 pm
1 stop9h 00m
$402
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 2/14
6:25 am-1:45 pm
1 stop6h 20m
George Town Owen Roberts Intl
Sat 2/21
2:50 pm-9:05 pm
1 stop7h 15m
$405
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 3/5
6:00 am-12:29 pm
1 stop5h 29m
George Town Owen Roberts Intl
Sat 3/7
12:25 pm-8:06 pm
1 stop8h 41m
$417
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 3/19
5:12 am-2:25 pm
1 stop9h 13m
George Town Owen Roberts Intl
Mon 3/23
3:30 pm-8:55 am
1 stop17h 25m
$417
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 4/23
6:54 pm-1:11 pm
2 stops18h 17m
George Town Owen Roberts Intl
Mon 4/27
12:35 pm-2:33 pm
1 stop25h 58m
$430
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 2/23
6:00 am-8:15 pm
2 stops13h 15m
$120
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 2/23
6:00 am-12:29 pm
1 stop5h 29m
$120
Showing 1-10 of 12 results
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $258). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated January 27, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$605 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$360 | Average$625 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$585 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$458 | Average$619 | FlexibilityNo cancel fee | On-time71% |