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Grand Cayman

$171+ Cheap flights from St. Louis (STL) to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from St. Louis to Grand Cayman

Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated September 17, 2025.

Round-trip from

$437
(Delta)

One-way from

$171
(Southwest)

Popular in

March

Cheapest in

September

Average price

$468
From Lambert-St Louis to Grand Cayman
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One-way flight from Lambert-St Louis to Grand Cayman
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Highest demand for flights based on searches. 8% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from St. Louis to Grand Cayman

Cheapest flights from St. Louis to Grand Cayman
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:00 amSTL - GCM
1 stop5h 35mDelta
Thu 10/2312:55 pmGCM - STL
1 stop8h 33mDelta
Deal found 9/16$446
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:52 amSTL - GCM
1 stop6h 18mAmerican Airlines
Wed 11/121:20 pmGCM - STL
1 stop10h 07mAmerican Airlines
Deal found 9/15$460
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:15 amSTL - GCM
1 stop9h 15mUnited Airlines
Fri 11/75:45 pmGCM - STL
2 stops19h 43mUnited Airlines
Deal found 9/16$464
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:20 amSTL - GCM
1 stop6h 05mAmerican Airlines
Sat 10/258:25 amGCM - STL
1 stop15h 31mAmerican Airlines
Deal found 9/15$474
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/198:05 pmSTL - GCM
2 stops15h 20mAmerican Airlines
Thu 10/232:00 pmGCM - STL
2 stops9h 49mAmerican Airlines
Deal found 9/16$495
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/272:01 pmSTL - GCM
2 stops21h 21mAmerican Airlines
Sat 10/113:05 pmGCM - STL
1 stop8h 13mAmerican Airlines
Deal found 9/15$563

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.

Fly from

St. Louis

Fly to

Grand Cayman

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Wed 1/28

2:00 pm-11:40 pm

1 stop10h 40m

$438

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Thu 1/29

2:00 pm-8:39 pm

1 stop7h 39m

$438

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Tue 2/3

2:00 pm-11:40 pm

1 stop10h 40m

$439

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 10/19

6:00 am-11:35 am

1 stop5h 35m

George Town Owen Roberts Intl

Thu 10/23

12:55 pm-9:28 pm

1 stop8h 33m

$446

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Fri 1/30

2:00 pm-11:40 pm

1 stop10h 40m

$446

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 11/7

5:06 pm-11:34 am

1 stop17h 28m

George Town Owen Roberts Intl

Wed 11/12

1:05 pm-11:07 pm

1 stop11h 02m

$460

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 10/31

6:00 am-11:41 am

1 stop5h 41m

George Town Owen Roberts Intl

Fri 11/7

2:00 pm-9:38 pm

1 stop8h 38m

$460

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 10/31

6:15 am-3:30 pm

1 stop9h 15m

George Town Owen Roberts Intl

Fri 11/7

5:45 pm-12:28 pm

2 stops19h 43m

$464

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 10/31

6:03 am-7:20 pm

2 stops13h 17m

George Town Owen Roberts Intl

Fri 11/7

12:55 pm-11:56 pm

2 stops12h 01m

$464

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 12/15

8:15 pm-12:35 pm

2 stops15h 20m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 11 results
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Best time to book a flight from St. Louis to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Grand Cayman

What is the cheapest month to book a flight from St. Louis to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $467). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated September 17, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Grand Cayman?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Grand Cayman. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How long is the flight from St. Louis to Grand Cayman?

    For as low as $438, Delta can have you in Grand Cayman from St. Louis in 5h 35m. Airlines will cover a distance of 1448 mi.

  • Can I find deals for flights from St. Louis to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on St. Louis to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Grand Cayman.

  • Can I find deals for business class flights from St. Louis to Grand Cayman?

    Yes. Cheapflights offers flight deals from St. Louis to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $467). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for St. Louis to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Kansas City to George Town flights
St. Louis to George Town flights

Top 4 airlines flying from St. Louis to Grand Cayman

Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$605FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$429Average$585FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$439Average$611FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$698FlexibilityNo cancel feeOn-time69%

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