$183+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Grand Cayman with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Air Canada deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm -
2 stops47h 15m
Sat 10/1011:25 am -
1 stop26h 35m
Deal found 8/28![Air Canada logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:29 am -
2 stops11h 31m
Sat 11/78:15 am -
1 stop10h 10m
Deal found 9/1![American Airlines logo]()
$422
This Orbitz deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:10 pm -
2 stops47h 15m
Thu 10/1512:25 pm -
2 stops30h 16m
Deal found 8/31![Air Canada logo]()
$470
This Travelocity deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:05 pm -
1 stop20h 05m
Sat 11/71:10 pm -
1 stop27h 16m
Deal found 8/28![Air Canada logo]()
$478
This Justfly.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:05 pm -
1 stop20h 05m
Fri 11/61:10 pm -
1 stop27h 16m
Deal found 8/28![Air Canada logo]()
$486
This Justfly.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:05 pm -
1 stop19h 05m
Fri 12/41:10 pm -
1 stop27h 16m
Deal found 8/30![Air Canada logo]()
$487
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop5h 40m
Sat 10/101:05 pm -
1 stop6h 51m
Deal found 8/28![Delta logo]()
$519
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:47 am -
2 stops12h 13m
Fri 11/612:54 pm -
2 stops12h 05m
Deal found 9/1![American Airlines logo]()
$524
Best flights from St. Louis to Grand CaymanDiscover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Justfly.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:05 pm -
1 stop20h 05m
Fri 11/61:10 pm -
1 stop27h 16m
Deal found 8/29![Air Canada logo]()
$486
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/163:05 pm -
2 stops20h 50m
Thu 1/211:50 pm -
2 stops18h 50m
Deal found 9/1![Southwest logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/165:17 am -
1 stop8h 13m
Thu 1/218:21 am -
1 stop10h 01m
Deal found 9/1![American Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:00 am -
2 stops10h 30m
Mon 11/95:45 pm -
2 stops17h 47m
Deal found 8/28![United Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop5h 40m
Sat 10/101:05 pm -
1 stop6h 51m
Deal found 8/29![Delta logo]()
$599
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:00 am -
2 stops10h 30m
Wed 11/45:45 pm -
2 stops17h 47m
Deal found 9/1![United Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:03 am -
2 stops11h 57m
Sat 11/78:15 am -
2 stops10h 20m
Deal found 8/28![American Airlines logo]()
$604
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/304:20 pm -
2 stops19h 35m
Sun 2/71:50 pm -
2 stops19h 00m
Deal found 8/29![Southwest logo]()
$604
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:32 am -
2 stops12h 28m
Fri 11/612:54 pm -
1 stop9h 53m
Deal found 8/28![American Airlines logo]()
$604
Last-minute flights from St. Louis to Grand CaymanDiscover last-minute flight deals from St. Louis to Grand Cayman. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Grand Cayman. Data last updated September 2, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm -
2 stops47h 15m
Sat 10/1011:25 am -
1 stop26h 35m
Deal found 8/28![Air Canada logo]()
$414
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop5h 40m
Sat 10/101:05 pm -
1 stop6h 51m
Deal found 8/28![Delta logo]()
$519
This Orbitz deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:10 pm -
2 stops47h 15m
Thu 10/1512:25 pm -
2 stops30h 16m
Deal found 8/31![Air Canada logo]()
$470
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:40 am -
2 stops13h 20m
Sat 11/78:15 am -
2 stops10h 39m
Deal found 9/1![American Airlines logo]()
$422
This Travelocity deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:05 pm -
1 stop20h 05m
Sat 11/71:10 pm -
1 stop27h 16m
Deal found 8/28![Air Canada logo]()
$478
This Justfly.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:05 pm -
1 stop20h 05m
Fri 11/61:10 pm -
1 stop27h 16m
Deal found 8/28![Air Canada logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:32 am -
2 stops12h 28m
Fri 11/612:54 pm -
1 stop9h 53m
Deal found 9/1![American Airlines logo]()
$524
One-way flights from St. Louis to Grand CaymanSearch for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:15 pm -
2 stops14h 40m
Deal found 8/31![American Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:28 pm -
3 stops49h 37m
Deal found 8/31![Multiple Airlines logo]()
$300
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated September 2, 2026.
Round-trip from | $414 (Air Canada) |
|---|---|
One-way from | $183 (American Airlines) |
Popular in | June |
Cheapest in | April |
Average price | $627 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 10/31
4:05 pm-12:10 pm
1 stop20h 05m
George Town Owen Roberts Intl
Fri 11/6
1:10 pm-3:26 pm
1 stop27h 16m
$486
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 1/16
3:05 pm-12:55 pm
2 stops20h 50m
George Town Owen Roberts Intl
Thu 1/21
1:50 pm-7:40 am
2 stops18h 50m
$504
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 1/16
5:17 am-2:30 pm
1 stop8h 13m
George Town Owen Roberts Intl
Thu 1/21
8:21 am-5:22 pm
1 stop10h 01m
$539
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Thu 11/5
5:00 am-4:30 pm
2 stops10h 30m
George Town Owen Roberts Intl
Mon 11/9
5:45 pm-10:32 am
2 stops17h 47m
$584
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Mon 11/2
5:00 am-4:30 pm
2 stops10h 30m
George Town Owen Roberts Intl
Wed 11/4
5:45 pm-10:32 am
2 stops17h 47m
$584
Quickest round-trip
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 9/26
6:00 am-11:40 am
1 stop5h 40m
George Town Owen Roberts Intl
Sat 10/10
1:05 pm-7:56 pm
1 stop6h 51m
$599
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 10/31
7:03 am-7:00 pm
2 stops11h 57m
George Town Owen Roberts Intl
Sat 11/7
8:15 am-5:35 pm
2 stops10h 20m
$604
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 1/30
4:20 pm-12:55 pm
2 stops19h 35m
George Town Owen Roberts Intl
Sun 2/7
1:50 pm-7:50 am
2 stops19h 00m
$604
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 10/31
6:32 am-7:00 pm
2 stops12h 28m
George Town Owen Roberts Intl
Fri 11/6
12:54 pm-9:47 pm
1 stop9h 53m
$604
Cheapest one-way
Quickest one-way
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sun 11/8
8:15 pm-11:55 am
2 stops14h 40m
$183
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
STL-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
STL-zzLAW
STL-GCM
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $502). Flying from St. Louis to Grand Cayman in June is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated September 2, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
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St. Louis and Grand Cayman flights
Browse other St. Louis and Grand Cayman flight options. Last updated on September 2, 2026.
Popular flight searches
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Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$237 | Average$597 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$364 | Average$559 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$483 | Average$774 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$492 | Average$682 | FlexibilityNo cancel fee | On-time71% |