$277+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Jun 8 — Jun 151
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Grand Cayman with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Grand Cayman
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Last-minute
One-way
Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
STL
- GCM
1 stop5h 34m
Delta
Tue 6/3012:59 pm
GCM
- STL
1 stop10h 57m
Delta
Deal found 5/5![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:13 pm
STL
- GCM
2 stops16h 48m
American Airlines
Tue 6/3012:01 pm
GCM
- STL
1 stop10h 56m
American Airlines
Deal found 5/5![American Airlines logo]()
$462
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:12 pm
STL
- GCM
1 stop17h 13m
American Airlines
Wed 7/2912:02 pm
GCM
- STL
1 stop10h 51m
American Airlines
Deal found 5/4![American Airlines logo]()
$466
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop6h 00m
American Airlines
Tue 8/2512:00 pm
GCM
- STL
2 stops10h 40m
American Airlines
Deal found 5/5![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:19 pm
STL
- GCM
1 stop16h 41m
American Airlines
Wed 7/2912:02 pm
GCM
- STL
1 stop10h 51m
American Airlines
Deal found 5/4![American Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:08 pm
STL
- GCM
1 stop17h 50m
American Airlines
Fri 11/64:10 pm
GCM
- STL
1 stop17h 17m
American Airlines
Deal found 5/5![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:20 pm
STL
- GCM
2 stops16h 10m
American Airlines
Sat 6/612:40 pm
GCM
- STL
1 stop11h 19m
American Airlines
Deal found 5/5![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
STL
- GCM
1 stop5h 39m
Delta
Tue 8/251:04 pm
GCM
- STL
1 stop10h 54m
Delta
Deal found 5/8![Delta logo]()
$499
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:33 pm
STL
- GCM
2 stops19h 17m
American Airlines
Fri 9/251:20 pm
GCM
- STL
1 stop9h 52m
American Airlines
Deal found 5/7![American Airlines logo]()
$504
Best flights from St. Louis to Grand CaymanDiscover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 9, 2026.
Discover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 9, 2026.
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
STL
- GCM
1 stop5h 34m
Delta
Tue 6/3012:59 pm
GCM
- STL
1 stop10h 57m
Delta
Deal found 5/4![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:55 pm
STL
- GCM
2 stops15h 30m
American Airlines
Wed 7/2912:02 pm
GCM
- STL
1 stop10h 51m
American Airlines
Deal found 5/4![American Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:14 am
STL
- GCM
1 stop9h 21m
United Airlines
Sat 6/131:50 pm
GCM
- STL
1 stop7h 31m
United Airlines
Deal found 5/6![United Airlines logo]()
$579
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
STL
- GCM
1 stop5h 39m
Delta
Tue 8/251:04 pm
GCM
- STL
1 stop10h 54m
Delta
Deal found 5/5![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop6h 00m
American Airlines
Tue 8/2512:00 pm
GCM
- STL
2 stops10h 40m
American Airlines
Deal found 5/5![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:40 pm
STL
- GCM
1 stop18h 00m
American Airlines
Fri 6/1212:01 pm
GCM
- STL
2 stops11h 58m
American Airlines
Deal found 5/4![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:00 am
STL
- GCM
1 stop5h 40m
Delta
Fri 9/2512:55 pm
GCM
- STL
1 stop10h 42m
Delta
Deal found 5/7![Delta logo]()
$499
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:12 pm
STL
- GCM
2 stops16h 49m
American Airlines
Sat 6/612:40 pm
GCM
- STL
1 stop11h 19m
American Airlines
Deal found 5/4![American Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:20 pm
STL
- GCM
1 stop15h 02m
American Airlines
Fri 6/2612:01 pm
GCM
- STL
1 stop10h 56m
American Airlines
Deal found 5/4![American Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:18 am
STL
- GCM
1 stop10h 52m
American Airlines
Tue 7/2812:02 pm
GCM
- STL
1 stop10h 51m
American Airlines
Deal found 5/7![American Airlines logo]()
$579
Last-minute flights from St. Louis to Grand CaymanDiscover last-minute flight deals from St. Louis to Grand Cayman. Data last updated May 9, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Grand Cayman. Data last updated May 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:20 pm
STL
- GCM
2 stops16h 10m
American Airlines
Sat 6/612:40 pm
GCM
- STL
1 stop11h 19m
American Airlines
Deal found 5/5![American Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:40 pm
STL
- GCM
1 stop18h 00m
American Airlines
Fri 6/1212:01 pm
GCM
- STL
1 stop10h 56m
American Airlines
Deal found 5/4![American Airlines logo]()
$625
This Expedia deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:05 pm
STL
- GCM
2 stops46h 20m
Air Canada
Sat 6/1310:55 am
GCM
- STL
1 stop25h 11m
Air Canada
Deal found 5/6![Air Canada logo]()
$581
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:13 pm
STL
- GCM
2 stops16h 48m
American Airlines
Sun 6/212:42 pm
GCM
- STL
1 stop9h 17m
American Airlines
Deal found 5/8![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:20 pm
STL
- GCM
1 stop15h 02m
American Airlines
Fri 6/2612:01 pm
GCM
- STL
1 stop10h 56m
American Airlines
Deal found 5/4![American Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:14 am
STL
- GCM
1 stop6h 16m
American Airlines
Sun 6/285:12 pm
GCM
- STL
1 stop17h 23m
American Airlines
Deal found 5/7![American Airlines logo]()
$600
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
STL
- GCM
1 stop5h 34m
Delta
Tue 6/3012:59 pm
GCM
- STL
1 stop10h 57m
Delta
Deal found 5/5![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:13 pm
STL
- GCM
2 stops16h 48m
American Airlines
Tue 6/3012:01 pm
GCM
- STL
1 stop10h 56m
American Airlines
Deal found 5/5![American Airlines logo]()
$462
One-way flights from St. Louis to Grand CaymanSearch for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated May 9, 2026.
Search for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated May 9, 2026.
This KAYAK deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:40 am
STL
- GCM
1 stop5h 30m
Southwest
Deal found 5/7![Southwest logo]()
$277
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated May 9, 2026.
Round-trip from | $457 (Delta) |
|---|---|
One-way from | $277 (KAYAK) |
Popular in | December |
Cheapest in | September |
Average price | $636 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 6/23
6:00 am-11:34 am
1 stop5h 34m
George Town Owen Roberts Intl
Tue 6/30
12:59 pm-11:56 pm
1 stop10h 57m
$457
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 8/19
6:00 am-11:39 am
1 stop5h 39m
George Town Owen Roberts Intl
Tue 8/25
1:04 pm-11:58 pm
1 stop10h 54m
$457
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 7/26
7:55 pm-11:25 am
2 stops15h 30m
George Town Owen Roberts Intl
Wed 7/29
12:02 pm-10:53 pm
1 stop10h 51m
$462
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 8/19
5:00 am-11:00 am
1 stop6h 00m
George Town Owen Roberts Intl
Tue 8/25
12:00 pm-10:40 pm
2 stops10h 40m
$467
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Fri 6/5
5:40 pm-11:40 am
1 stop18h 00m
George Town Owen Roberts Intl
Fri 6/12
12:01 pm-11:59 pm
2 stops11h 58m
$497
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 5/30
6:12 pm-11:01 am
2 stops16h 49m
George Town Owen Roberts Intl
Sat 6/6
12:40 pm-11:59 pm
1 stop11h 19m
$497
Quickest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 9/21
6:00 am-11:40 am
1 stop5h 40m
George Town Owen Roberts Intl
Fri 9/25
12:55 pm-11:37 pm
1 stop10h 42m
$499
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Fri 6/19
7:20 pm-10:22 am
1 stop15h 02m
George Town Owen Roberts Intl
Fri 6/26
12:01 pm-10:57 pm
1 stop10h 56m
$553
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 6/6
6:14 am-3:35 pm
1 stop9h 21m
George Town Owen Roberts Intl
Sat 6/13
1:50 pm-9:21 pm
1 stop7h 31m
$579
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 7/21
5:18 am-4:10 pm
1 stop10h 52m
George Town Owen Roberts Intl
Tue 7/28
12:02 pm-10:53 pm
1 stop10h 51m
$579
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
STL-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
STL-zzLAW
STL-GCM
How far ahead should I book a flight from St. Louis to Grand Cayman?
The best time to book flights from St. Louis to Grand Cayman is 68 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $190). Flying from St. Louis to Grand Cayman in June is currently the most expensive (average of $537). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated May 9, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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St. Louis and Grand Cayman flights
Browse other St. Louis and Grand Cayman flight options. Last updated on May 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$583 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$364 | Average$625 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$424 | Average$632 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$429 | Average$615 | FlexibilityNo cancel fee | On-time63% |