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Grand Cayman

$145+ Cheap flights from St. Louis (STL) to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from St. Louis to Grand Cayman

Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated August 20, 2025.

Round-trip from

$394
(American Airlines)

One-way from

$145
(United Airlines)

Popular in

March

Cheapest in

January

Average price

$589
From Lambert-St Louis to Grand Cayman
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One-way flight from Lambert-St Louis to Grand Cayman
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Highest demand for flights based on searches. 9% potential increase in price ($60 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from St. Louis to Grand Cayman

Cheapest flights from St. Louis to Grand Cayman
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:02 pmSTL - GCM
1 stop16h 03mAmerican Airlines
Fri 12/125:35 pmGCM - STL
1 stop6h 59mAmerican Airlines
Deal found 8/18$394
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:27 amSTL - GCM
1 stop5h 55mAmerican Airlines
Thu 10/912:25 pmGCM - STL
1 stop11h 33mAmerican Airlines
Deal found 8/18$419
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:59 pmSTL - GCM
2 stops19h 23mAmerican Airlines
Sat 10/118:25 amGCM - STL
2 stops14h 53mAmerican Airlines
Deal found 8/19$423
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/184:25 pmSTL - GCM
1 stop19h 00mAmerican Airlines
Sat 10/258:25 amGCM - STL
2 stops12h 28mAmerican Airlines
Deal found 8/18$431
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:27 amSTL - GCM
1 stop5h 55mAmerican Airlines
Sat 9/2012:10 pmGCM - STL
1 stop11h 49mAmerican Airlines
Deal found 8/18$444
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:11 pmSTL - GCM
2 stops20h 59mAmerican Airlines
Sun 10/512:10 pmGCM - STL
1 stop11h 49mAmerican Airlines
Deal found 8/19$453
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/178:17 amSTL - GCM
1 stop27h 05mAmerican Airlines
Sat 9/2012:25 pmGCM - STL
2 stops21h 01mAmerican Airlines
Deal found 8/18$457

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.

Fly from

St. Louis

Fly to

Grand Cayman

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 12/6

7:02 pm-12:05 pm

1 stop16h 03m

George Town Owen Roberts Intl

Fri 12/12

5:35 pm-11:34 pm

1 stop6h 59m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Thu 1/29

2:00 pm-11:40 pm

1 stop10h 40m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Tue 2/3

2:00 pm-11:40 pm

1 stop10h 40m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 1/25

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Thu 1/29

2:00 pm-8:39 pm

1 stop7h 39m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 1/25

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Tue 2/3

2:00 pm-11:40 pm

1 stop10h 40m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 1/27

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Wed 1/28

2:00 pm-11:40 pm

1 stop10h 40m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Fri 1/30

2:00 pm-11:40 pm

1 stop10h 40m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 1/27

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Fri 1/30

3:45 pm-11:10 pm

1 stop8h 25m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Wed 1/28

2:00 pm-11:40 pm

1 stop10h 40m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 1/27

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Tue 2/3

2:00 pm-11:40 pm

1 stop10h 40m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 15 results
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Best time to book a flight from St. Louis to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Grand Cayman

What is the cheapest month to book a flight from St. Louis to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $467). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated August 20, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,928 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Grand Cayman?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Grand Cayman. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How long is the flight from St. Louis to Grand Cayman?

    For as low as $394, American Airlines can have you in Grand Cayman from St. Louis in 5h 35m. Airlines will cover a distance of 1448 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from St. Louis to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on St. Louis to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Grand Cayman.

  • Can I find deals for business class flights from St. Louis to Grand Cayman?

    Yes. Cheapflights offers flight deals from St. Louis to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $467). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Kansas City to George Town flights
St. Louis to George Town flights

Top 4 airlines flying from St. Louis to Grand Cayman

Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$266Average$605FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$429Average$585FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$439Average$616FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$625FlexibilityNo cancel feeOn-time69%

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