$177+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Jul 25 — Aug 11
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Grand Cayman with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Last-minute
One-way
Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:45 pm
STL
- GCM
1 stop16h 15m
American Airlines
Tue 12/159:00 am
GCM
- STL
1 stop15h 59m
American Airlines
Deal found 6/23![American Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop6h 00m
American Airlines
Tue 8/2512:00 pm
GCM
- STL
2 stops10h 55m
American Airlines
Deal found 6/25![American Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:13 pm
STL
- GCM
1 stop20h 47m
American Airlines
Tue 9/2912:00 pm
GCM
- STL
1 stop9h 49m
American Airlines
Deal found 6/22![American Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:02 am
STL
- GCM
1 stop5h 58m
American Airlines
Sun 12/133:14 pm
GCM
- STL
1 stop23h 04m
American Airlines
Deal found 6/23![American Airlines logo]()
$495
This FlightHub deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Fri 11/61:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/21![Air Canada logo]()
$496
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/811:35 am
STL
- GCM
1 stop23h 25m
American Airlines
Sat 8/154:00 pm
GCM
- STL
1 stop16h 31m
American Airlines
Deal found 6/24![American Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:00 am
STL
- GCM
1 stop8h 10m
American Airlines
Thu 8/1312:30 pm
GCM
- STL
1 stop10h 10m
American Airlines
Deal found 6/22![American Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
STL
- GCM
1 stop5h 25m
Delta
Tue 11/171:50 pm
GCM
- STL
1 stop7h 59m
Delta
Deal found 6/24![Delta logo]()
$525
Best flights from St. Louis to Grand CaymanDiscover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
Discover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:45 pm
STL
- GCM
1 stop16h 15m
American Airlines
Tue 12/159:00 am
GCM
- STL
1 stop15h 59m
American Airlines
Deal found 6/20![American Airlines logo]()
$459
This Justfly.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Fri 11/61:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/20![Air Canada logo]()
$496
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:50 am
STL
- GCM
1 stop6h 40m
United Airlines
Wed 12/95:45 pm
GCM
- STL
1 stop16h 57m
United Airlines
Deal found 6/21![United Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop8h 10m
American Airlines
Tue 8/2512:30 pm
GCM
- STL
1 stop10h 25m
American Airlines
Deal found 6/25![American Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:00 am
STL
- GCM
1 stop8h 10m
American Airlines
Thu 8/1312:30 pm
GCM
- STL
1 stop10h 10m
American Airlines
Deal found 6/22![American Airlines logo]()
$519
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:07 am
STL
- GCM
1 stop5h 56m
American Airlines
Wed 7/2912:02 pm
GCM
- STL
1 stop10h 52m
American Airlines
Deal found 6/24![American Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:32 am
STL
- GCM
1 stop8h 04m
American Airlines
Mon 7/2712:33 pm
GCM
- STL
1 stop11h 25m
American Airlines
Deal found 6/20![American Airlines logo]()
$579
Last-minute flights from St. Louis to Grand CaymanDiscover last-minute flight deals from St. Louis to Grand Cayman. Data last updated June 25, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Grand Cayman. Data last updated June 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:10 am
STL
- GCM
1 stop6h 15m
American Airlines
Mon 7/132:41 pm
GCM
- STL
1 stop7h 07m
American Airlines
Deal found 6/22![American Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:10 am
STL
- GCM
1 stop9h 53m
American Airlines
Sat 7/182:19 pm
GCM
- STL
1 stop18h 14m
American Airlines
Deal found 6/25![American Airlines logo]()
$707
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:10 am
STL
- GCM
1 stop6h 15m
American Airlines
Thu 7/235:10 pm
GCM
- STL
1 stop17h 14m
American Airlines
Deal found 6/20![American Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:18 am
STL
- GCM
1 stop10h 52m
American Airlines
Sun 7/265:10 pm
GCM
- STL
1 stop17h 14m
American Airlines
Deal found 6/22![American Airlines logo]()
$652
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:07 am
STL
- GCM
1 stop5h 56m
American Airlines
Wed 7/2912:02 pm
GCM
- STL
1 stop10h 52m
American Airlines
Deal found 6/24![American Airlines logo]()
$579
One-way flights from St. Louis to Grand CaymanSearch for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
Search for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:18 pm
STL
- GCM
2 stops18h 09m
American Airlines
Deal found 6/21![American Airlines logo]()
$177
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:30 am
STL
- GCM
1 stop5h 30m
American Airlines
Deal found 6/23![American Airlines logo]()
$182
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:55 am
STL
- GCM
1 stop26h 30m
Air Canada
Deal found 6/22![Air Canada logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:57 pm
STL
- GCM
2 stops42h 38m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:57 pm
STL
- GCM
2 stops42h 38m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$220
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:00 am
STL
- GCM
2 stops10h 00m
American Airlines
Deal found 6/22![American Airlines logo]()
$237
This Orbitz deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:40 pm
STL
- GCM
1 stop19h 15m
Air Canada
Deal found 6/23![Air Canada logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:46 pm
STL
- GCM
3 stops27h 19m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:57 pm
STL
- GCM
3 stops24h 23m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:46 pm
STL
- GCM
3 stops32h 29m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$321
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated June 25, 2026.
Round-trip from | $459 (American Airlines) |
|---|---|
One-way from | $177 (American Airlines) |
Popular in | June |
Cheapest in | April |
Average price | $782 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 12/1
6:45 pm-12:00 pm
1 stop16h 15m
George Town Owen Roberts Intl
Tue 12/15
9:00 am-11:59 pm
1 stop15h 59m
$459
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 8/19
5:00 am-1:10 pm
1 stop8h 10m
George Town Owen Roberts Intl
Tue 8/25
12:30 pm-10:55 pm
1 stop10h 25m
$464
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 10/31
4:15 pm-12:00 pm
1 stop19h 45m
George Town Owen Roberts Intl
Fri 11/6
1:10 pm-3:30 pm
1 stop27h 20m
$496
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 8/6
5:00 am-1:10 pm
1 stop8h 10m
George Town Owen Roberts Intl
Thu 8/13
12:30 pm-10:40 pm
1 stop10h 10m
$519
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 12/8
8:50 am-4:30 pm
1 stop6h 40m
George Town Owen Roberts Intl
Wed 12/9
5:45 pm-9:42 am
1 stop16h 57m
$579
Quickest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 7/25
9:07 am-3:03 pm
1 stop5h 56m
George Town Owen Roberts Intl
Wed 7/29
12:02 pm-10:54 pm
1 stop10h 52m
$579
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 7/20
5:32 am-1:36 pm
1 stop8h 04m
George Town Owen Roberts Intl
Mon 7/27
12:33 pm-11:58 pm
1 stop11h 25m
$579
Cheapest one-way
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 9/15
5:18 pm-11:27 am
2 stops18h 09m
$177
Quickest one-way
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 10/7
5:30 am-11:00 am
1 stop5h 30m
$182
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 7/22
4:57 pm-11:35 am
2 stops42h 38m
$204
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
STL-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
STL-zzLAW
STL-GCM
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, January is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $198). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated June 25, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from St. Louis to Grand Cayman, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Grand Cayman flights
Browse other St. Louis and Grand Cayman flight options. Last updated on June 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$346 | Average$597 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$364 | Average$689 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$578 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$458 | Average$632 | FlexibilityNo cancel fee | On-time71% |