$147+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Mar 10 — Mar 171
1 adult, Economy
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Find cheap flights from St. Louis to Grand Cayman with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Last-minute
One-way
Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
STL
- GCM
1 stop6h 30m
United Airlines
Mon 4/131:35 pm
GCM
- STL
1 stop8h 53m
United Airlines
Deal found 2/7![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:05 am
STL
- GCM
1 stop6h 50m
Southwest
Fri 5/221:05 pm
GCM
- STL
2 stops10h 20m
Southwest
Deal found 2/7![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:54 pm
STL
- GCM
2 stops18h 16m
American Airlines
Fri 5/222:40 pm
GCM
- STL
1 stop25h 53m
American Airlines
Deal found 2/7![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Mon 3/22:50 pm
GCM
- STL
1 stop7h 15m
United Airlines
Deal found 2/5![United Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Tue 3/174:45 pm
GCM
- STL
1 stop16h 36m
United Airlines
Deal found 2/5![United Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:00 am
STL
- GCM
2 stops11h 15m
American Airlines
Tue 3/1712:00 pm
GCM
- STL
2 stops11h 44m
American Airlines
Deal found 2/5![American Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:14 am
STL
- GCM
1 stop5h 51m
American Airlines
Tue 3/33:35 pm
GCM
- STL
1 stop9h 13m
American Airlines
Deal found 2/7![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:30 am
STL
- GCM
1 stop6h 15m
United Airlines
Mon 4/271:35 pm
GCM
- STL
1 stop8h 53m
United Airlines
Deal found 2/7![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
STL
- GCM
1 stop9h 30m
United Airlines
Mon 3/91:25 pm
GCM
- STL
1 stop10h 26m
United Airlines
Deal found 2/4![United Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:53 pm
STL
- GCM
1 stop16h 40m
American Airlines
Sat 5/23:13 pm
GCM
- STL
1 stop7h 44m
American Airlines
Deal found 2/7![American Airlines logo]()
$377
Best flights from St. Louis to Grand CaymanDiscover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
Discover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
STL
- GCM
1 stop5h 54m
Delta
Fri 5/221:19 pm
GCM
- STL
1 stop10h 40m
Delta
Deal found 2/7![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
STL
- GCM
1 stop6h 30m
United Airlines
Mon 4/131:35 pm
GCM
- STL
1 stop8h 53m
United Airlines
Deal found 2/7![United Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:54 pm
STL
- GCM
2 stops18h 16m
American Airlines
Fri 5/222:10 pm
GCM
- STL
2 stops18h 21m
American Airlines
Deal found 2/7![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Mon 3/22:50 pm
GCM
- STL
1 stop7h 15m
United Airlines
Deal found 2/5![United Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:00 am
STL
- GCM
2 stops11h 15m
American Airlines
Tue 3/1712:00 pm
GCM
- STL
2 stops11h 44m
American Airlines
Deal found 2/5![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Tue 3/174:45 pm
GCM
- STL
1 stop16h 36m
United Airlines
Deal found 2/5![United Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
STL
- GCM
1 stop7h 25m
American Airlines
Tue 3/38:45 am
GCM
- STL
1 stop16h 11m
American Airlines
Deal found 2/6![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:30 am
STL
- GCM
1 stop6h 15m
United Airlines
Mon 4/271:35 pm
GCM
- STL
1 stop8h 53m
United Airlines
Deal found 2/7![United Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:53 pm
STL
- GCM
1 stop16h 40m
American Airlines
Sat 5/23:13 pm
GCM
- STL
1 stop7h 44m
American Airlines
Deal found 2/6![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
STL
- GCM
1 stop9h 30m
United Airlines
Mon 3/91:25 pm
GCM
- STL
1 stop10h 26m
United Airlines
Deal found 2/4![United Airlines logo]()
$372
Last-minute flights from St. Louis to Grand CaymanDiscover last-minute flight deals from St. Louis to Grand Cayman. Data last updated February 8, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Grand Cayman. Data last updated February 8, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:00 am
STL
- GCM
1 stop5h 29m
Delta
Wed 2/251:54 pm
GCM
- STL
1 stop10h 42m
Delta
Deal found 2/7![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Mon 3/22:50 pm
GCM
- STL
1 stop7h 15m
United Airlines
Deal found 2/5![United Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
STL
- GCM
2 stops13h 15m
American Airlines
Mon 3/24:25 pm
GCM
- STL
1 stop7h 57m
American Airlines
Deal found 2/5![American Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:14 am
STL
- GCM
1 stop5h 51m
American Airlines
Tue 3/33:35 pm
GCM
- STL
1 stop9h 13m
American Airlines
Deal found 2/7![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
STL
- GCM
1 stop9h 30m
United Airlines
Mon 3/91:25 pm
GCM
- STL
1 stop10h 26m
United Airlines
Deal found 2/4![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Tue 3/174:45 pm
GCM
- STL
1 stop16h 36m
United Airlines
Deal found 2/5![United Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:00 am
STL
- GCM
2 stops11h 15m
American Airlines
Tue 3/1712:00 pm
GCM
- STL
2 stops11h 44m
American Airlines
Deal found 2/5![American Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:12 am
STL
- GCM
1 stop9h 13m
American Airlines
Thu 3/263:30 pm
GCM
- STL
1 stop17h 25m
American Airlines
Deal found 2/5![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:25 am
STL
- GCM
1 stop6h 20m
United Airlines
Tue 3/311:35 pm
GCM
- STL
1 stop8h 53m
United Airlines
Deal found 2/7![United Airlines logo]()
$411
One-way flights from St. Louis to Grand CaymanSearch for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
Search for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:00 am
STL
- GCM
1 stop7h 25m
American Airlines
Deal found 2/7![American Airlines logo]()
$147
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:05 am
STL
- GCM
1 stop6h 09m
American Airlines
Deal found 2/6![American Airlines logo]()
$177
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:50 pm
STL
- GCM
2 stops17h 05m
Southwest
Deal found 2/6![Southwest logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:50 am
STL
- GCM
3 stops29h 15m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$355
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated February 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (United Airlines) |
One-way from | $147 (American Airlines) |
Popular in | March |
Cheapest in | September |
Average price | $708 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
St. Louis
Fly to
Grand Cayman
Route
Depart
Return
Price
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 5/17
6:00 am-11:54 am
1 stop5h 54m
George Town Owen Roberts Intl
Fri 5/22
1:19 pm-11:59 pm
1 stop10h 40m
$317
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 4/8
6:00 am-12:30 pm
1 stop6h 30m
George Town Owen Roberts Intl
Mon 4/13
1:35 pm-10:28 pm
1 stop8h 53m
$317
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 5/17
6:54 pm-1:10 pm
2 stops18h 16m
George Town Owen Roberts Intl
Fri 5/22
2:10 pm-8:31 am
2 stops18h 21m
$322
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 2/23
6:25 am-1:45 pm
1 stop6h 20m
George Town Owen Roberts Intl
Mon 3/2
2:50 pm-9:05 pm
1 stop7h 15m
$331
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 3/10
6:25 am-12:45 pm
1 stop6h 20m
George Town Owen Roberts Intl
Tue 3/17
4:45 pm-9:21 am
1 stop16h 36m
$342
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 3/10
8:00 am-7:15 pm
2 stops11h 15m
George Town Owen Roberts Intl
Tue 3/17
12:00 pm-11:44 pm
2 stops11h 44m
$347
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Tue 2/24
7:00 am-3:25 pm
1 stop7h 25m
George Town Owen Roberts Intl
Tue 3/3
8:45 am-11:56 pm
1 stop16h 11m
$358
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 4/23
6:30 am-12:45 pm
1 stop6h 15m
George Town Owen Roberts Intl
Mon 4/27
1:35 pm-10:28 pm
1 stop8h 53m
$364
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 3/5
6:00 am-4:30 pm
1 stop9h 30m
George Town Owen Roberts Intl
Mon 3/9
1:25 pm-11:51 pm
1 stop10h 26m
$372
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 4/18
6:53 pm-11:33 am
1 stop16h 40m
George Town Owen Roberts Intl
Sat 5/2
3:13 pm-10:57 pm
1 stop7h 44m
$377
Showing 1-10 of 14 results
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
STL-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
STL-zzLAW
STL-GCM
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $258). Flying from St. Louis to Grand Cayman in March is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated February 8, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for St. Louis to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Grand Cayman by cabin class
Find flights from St. Louis to Grand Cayman, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Grand Cayman flights
Browse other St. Louis and Grand Cayman flight options. Last updated on February 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$605 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$360 | Average$600 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$585 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$446 | Average$619 | FlexibilityNo cancel fee | On-time71% |