$360+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Jan 25 — Feb 11
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Grand Cayman
Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:15 amSTL - GCM
1 stop7h 20mUnited Airlines
Thu 1/12:50 pmGCM - STL
1 stop8h 53mUnited Airlines
Deal found 12/24![United Airlines logo]()
$694
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amSTL - GCM
1 stop7h 27mDelta
Sun 12/283:42 pmGCM - STL
1 stop7h 01mDelta
Deal found 12/25![Delta logo]()
$744
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:04 pmSTL - GCM
2 stops21h 01mAmerican Airlines
Sun 12/2812:55 pmGCM - STL
2 stops9h 50mAmerican Airlines
Deal found 12/25![American Airlines logo]()
$779
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated December 26, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $360 (American Airlines) |
Popular in | March |
Cheapest in | September |
Average price | $662 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
St. Louis
Fly to
Grand Cayman
Route
Depart
Return
Price
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 1/21
6:00 am-2:35 pm
1 stop7h 35m
George Town Owen Roberts Intl
Wed 1/28
8:50 am-5:22 pm
1 stop9h 32m
$360
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 4/18
4:05 pm-11:10 am
1 stop19h 05m
George Town Owen Roberts Intl
Sat 5/2
12:25 pm-12:06 pm
1 stop23h 41m
$366
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 1/25
4:05 pm-12:25 pm
1 stop19h 20m
George Town Owen Roberts Intl
Thu 1/29
1:30 pm-3:29 pm
1 stop26h 59m
$381
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 2/2
6:00 am-12:40 pm
1 stop5h 40m
George Town Owen Roberts Intl
Sat 2/7
2:05 pm-11:36 pm
1 stop10h 31m
$390
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 2/2
6:30 am-1:45 pm
1 stop6h 15m
George Town Owen Roberts Intl
Sat 2/7
5:45 pm-12:29 pm
2 stops19h 44m
$395
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 4/18
7:03 pm-12:45 pm
2 stops17h 42m
George Town Owen Roberts Intl
Sat 5/2
1:15 pm-10:25 pm
2 stops9h 10m
$464
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $258). Flying from St. Louis to Grand Cayman in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated December 26, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$266 | Average$613 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$406 | Average$724 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$581 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$439 | Average$623 | FlexibilityNo cancel fee | On-time71% |