$157+ Cheap flights from St. Louis (STL) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Sep 1 — Sep 81
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Grand Cayman with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Grand Cayman
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Grand CaymanExplore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
This Gotogate deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:40 pm
STL
- GCM
1 stop20h 50m
Air Canada
Sat 10/2412:25 pm
GCM
- STL
1 stop7h 35m
Air Canada
Deal found 8/2![Air Canada logo]()
$374
This Expedia deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:10 pm
STL
- GCM
2 stops47h 20m
Air Canada
Sat 10/2412:25 pm
GCM
- STL
1 stop7h 35m
Air Canada
Deal found 8/1![Air Canada logo]()
$400
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:00 am
STL
- GCM
1 stop6h 00m
American Airlines
Sat 9/1911:55 am
GCM
- STL
2 stops10h 47m
American Airlines
Deal found 7/30![American Airlines logo]()
$411
This Air Canada deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:55 am
STL
- GCM
1 stop26h 30m
Air Canada
Mon 9/1412:25 pm
GCM
- STL
1 stop25h 35m
Air Canada
Deal found 8/1![Air Canada logo]()
$415
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:15 am
STL
- GCM
1 stop6h 15m
American Airlines
Fri 9/2512:36 pm
GCM
- STL
1 stop10h 06m
American Airlines
Deal found 7/29![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:18 pm
STL
- GCM
2 stops18h 12m
American Airlines
Sat 10/103:15 pm
GCM
- STL
1 stop8h 27m
American Airlines
Deal found 7/30![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:25 pm
STL
- GCM
2 stops19h 35m
American Airlines
Sun 8/302:10 pm
GCM
- STL
1 stop8h 30m
American Airlines
Deal found 7/30![American Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:54 pm
STL
- GCM
1 stop21h 33m
American Airlines
Sat 9/1211:55 am
GCM
- STL
2 stops20h 35m
American Airlines
Deal found 7/30![American Airlines logo]()
$437
This flygcity.se deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:08 pm
STL
- GCM
2 stops17h 52m
Multiple Airlines
Sat 10/2412:25 pm
GCM
- STL
1 stop7h 35m
Multiple Airlines
Deal found 8/2![Multiple Airlines logo]()
$439
Best flights from St. Louis to Grand CaymanDiscover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
Discover carefully curated flight deals from St. Louis to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
This Expedia deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:10 pm
STL
- GCM
2 stops47h 20m
Air Canada
Sat 10/2412:25 pm
GCM
- STL
1 stop7h 35m
Air Canada
Deal found 8/1![Air Canada logo]()
$400
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:45 pm
STL
- GCM
2 stops17h 15m
American Airlines
Sat 9/1911:55 am
GCM
- STL
2 stops10h 47m
American Airlines
Deal found 7/31![American Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:28 am
STL
- GCM
1 stop6h 02m
American Airlines
Mon 10/2612:35 pm
GCM
- STL
1 stop11h 24m
American Airlines
Deal found 8/1![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:15 am
STL
- GCM
1 stop6h 15m
American Airlines
Fri 9/2512:36 pm
GCM
- STL
1 stop10h 06m
American Airlines
Deal found 7/29![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:18 pm
STL
- GCM
2 stops18h 12m
American Airlines
Sat 10/103:15 pm
GCM
- STL
1 stop8h 27m
American Airlines
Deal found 7/29![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am
STL
- GCM
2 stops13h 00m
American Airlines
Fri 11/63:45 pm
GCM
- STL
1 stop7h 02m
American Airlines
Deal found 7/30![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 pm
STL
- GCM
2 stops17h 47m
American Airlines
Mon 9/1412:00 pm
GCM
- STL
2 stops20h 46m
American Airlines
Deal found 8/1![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:18 pm
STL
- GCM
2 stops18h 09m
American Airlines
Sat 9/1212:36 pm
GCM
- STL
2 stops20h 48m
American Airlines
Deal found 8/2![American Airlines logo]()
$429
Last-minute flights from St. Louis to Grand CaymanDiscover last-minute flight deals from St. Louis to Grand Cayman. Data last updated August 2, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Grand Cayman. Data last updated August 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:00 am
STL
- GCM
1 stop6h 00m
American Airlines
Fri 8/1412:00 pm
GCM
- STL
1 stop10h 40m
American Airlines
Deal found 7/31![American Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:07 pm
STL
- GCM
2 stops17h 03m
American Airlines
Sun 8/1612:00 pm
GCM
- STL
2 stops11h 34m
American Airlines
Deal found 8/2![American Airlines logo]()
$727
This Mytrip deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:48 am
STL
- GCM
3 stops26h 37m
Multiple Airlines
Sun 8/166:10 pm
GCM
- STL
2 stops26h 14m
Multiple Airlines
Deal found 8/2![Multiple Airlines logo]()
$2,671
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop8h 10m
American Airlines
Tue 8/2512:30 pm
GCM
- STL
1 stop10h 25m
American Airlines
Deal found 7/29![American Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
STL
- GCM
1 stop5h 39m
Delta
Tue 8/251:04 pm
GCM
- STL
1 stop10h 17m
Delta
Deal found 7/31![Delta logo]()
$623
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:42 pm
STL
- GCM
2 stops17h 18m
American Airlines
Sun 8/3012:00 pm
GCM
- STL
2 stops11h 34m
American Airlines
Deal found 7/30![American Airlines logo]()
$429
One-way flights from St. Louis to Grand CaymanSearch for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
Search for one-way flight options from St. Louis to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:00 am
STL
- GCM
1 stop13h 58m
American Airlines
Deal found 8/1![American Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:31 pm
STL
- GCM
3 stops20h 49m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$604
Find flight deals from St. Louis to Grand Cayman
Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated August 2, 2026.
Round-trip from | $374 (Gotogate) |
|---|---|
One-way from | $157 (American Airlines) |
Popular in | June |
Cheapest in | April |
Average price | $638 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 10/17
12:10 pm-11:30 am
2 stops47h 20m
George Town Owen Roberts Intl
Sat 10/24
12:25 pm-8:00 pm
1 stop7h 35m
$400
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 9/10
5:45 pm-11:00 am
2 stops17h 15m
George Town Owen Roberts Intl
Sat 9/19
11:55 am-10:42 pm
2 stops10h 47m
$413
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 10/19
5:28 am-11:30 am
1 stop6h 02m
George Town Owen Roberts Intl
Mon 10/26
12:35 pm-11:59 pm
1 stop11h 24m
$419
Quickest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 9/20
5:15 am-11:30 am
1 stop6h 15m
George Town Owen Roberts Intl
Fri 9/25
12:36 pm-10:42 pm
1 stop10h 06m
$419
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 9/26
5:18 pm-11:30 am
2 stops18h 12m
George Town Owen Roberts Intl
Sat 10/10
3:15 pm-11:42 pm
1 stop8h 27m
$424
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 10/31
6:00 am-7:00 pm
2 stops13h 00m
George Town Owen Roberts Intl
Fri 11/6
3:45 pm-9:47 pm
1 stop7h 02m
$424
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 9/6
5:40 pm-11:27 am
2 stops17h 47m
George Town Owen Roberts Intl
Mon 9/14
12:00 pm-8:46 am
2 stops20h 46m
$424
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 9/9
5:18 pm-11:27 am
2 stops18h 09m
George Town Owen Roberts Intl
Sat 9/12
12:36 pm-9:24 am
2 stops20h 48m
$429
Cheapest one-way
Quickest one-way
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 11/28
5:00 am-7:58 pm
1 stop13h 58m
$157
Sorted by cheapest first
Best time to book a flight from St. Louis to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
STL-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Grand Cayman
STL-zzLAW
STL-GCM
What is the cheapest month to book a flight from St. Louis to Grand Cayman?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $502). Flying from St. Louis to Grand Cayman in June is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated August 2, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
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St. Louis and Grand Cayman flights
Browse other St. Louis and Grand Cayman flight options. Last updated on August 2, 2026.
Popular flight searches
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Top 4 airlines flying from St. Louis to Grand Cayman
Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$237 | Average$586 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$364 | Average$604 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$433 | Average$578 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$464 | Average$662 | FlexibilityNo cancel fee | On-time71% |