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Grand Cayman

$338+ Cheap flights from St. Louis (STL) to Grand Cayman

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Find flight deals from St. Louis to Grand Cayman

Cheapest flights from St. Louis to Grand Cayman
Explore the most affordable flight options available from St. Louis to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amSTL - GCM
1 stop5h 30mDelta
Sat 12/131:55 pmGCM - STL
1 stop9h 02mDelta
Deal found 11/9$346
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:42 pmSTL - GCM
2 stops20h 48mUnited Airlines
Wed 12/175:45 pmGCM - STL
1 stop17h 04mUnited Airlines
Deal found 11/9$351
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:30 amSTL - GCM
2 stops9h 05mUnited Airlines
Sat 12/135:30 pmGCM - STL
2 stops19h 45mUnited Airlines
Deal found 11/9$382
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amSTL - GCM
1 stop5h 35mDelta
Mon 11/171:50 pmGCM - STL
1 stop10h 54mDelta
Deal found 11/8$384
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:30 amSTL - GCM
2 stops9h 00mUnited Airlines
Mon 11/175:45 pmGCM - STL
2 stops23h 02mUnited Airlines
Deal found 11/8$389
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amSTL - GCM
1 stop9h 00mUnited Airlines
Sun 12/285:45 pmGCM - STL
2 stops19h 42mUnited Airlines
Deal found 11/9$418
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:02 amSTL - GCM
2 stops14h 13mAmerican Airlines
Sat 12/1312:20 pmGCM - STL
2 stops11h 27mAmerican Airlines
Deal found 11/9$431
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amSTL - GCM
1 stop9h 00mUnited Airlines
Thu 1/15:45 pmGCM - STL
1 stop17h 04mUnited Airlines
Deal found 11/9$459
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amSTL - GCM
1 stop7h 27mDelta
Sun 12/283:42 pmGCM - STL
1 stop7h 01mDelta
Deal found 11/8$509

Cheap flight deals from St. Louis to Grand Cayman

Keep the following information in mind while searching for St. Louis to Grand Cayman flight deals. Data was last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$338
(Delta)

Popular in

March

Cheapest in

September

Average price

$544
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
Search Deals
From Lambert-St Louis to Grand Cayman
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from St. Louis to Grand Cayman that are best for you.

Fly from

St. Louis

Fly to

Grand Cayman

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-8:39 pm

1 stop7h 34m

$338

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

6:10 am-2:40 pm

1 stop7h 30m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-11:39 pm

1 stop10h 34m

$338

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

5:29 pm-12:50 pm

1 stop18h 21m

George Town Owen Roberts Intl

Thu 1/29

2:05 pm-8:39 pm

1 stop7h 34m

$338

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/24

7:10 am-2:00 pm

1 stop5h 50m

George Town Owen Roberts Intl

Wed 1/28

2:05 pm-11:39 pm

1 stop10h 34m

$338

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

6:10 am-2:40 pm

1 stop7h 30m

George Town Owen Roberts Intl

Mon 2/2

2:05 pm-8:39 pm

1 stop7h 34m

$338

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

6:57 pm-10:57 am

1 stop15h 00m

George Town Owen Roberts Intl

Wed 1/28

2:05 pm-8:39 pm

1 stop7h 34m

$338

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/19

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Mon 1/26

2:05 pm-11:39 pm

1 stop10h 34m

$346

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

5:56 pm-11:19 am

1 stop16h 23m

George Town Owen Roberts Intl

Tue 1/27

2:05 pm-8:39 pm

1 stop7h 34m

$346

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 1/13

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Mon 1/26

2:05 pm-11:39 pm

1 stop10h 34m

$346

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

6:10 am-2:40 pm

1 stop7h 30m

George Town Owen Roberts Intl

Mon 1/26

2:05 pm-11:39 pm

1 stop10h 34m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 11 results
1
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Best time to book a flight from St. Louis to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Grand Cayman

What is the cheapest month to book a flight from St. Louis to Grand Cayman?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $267). Flying from St. Louis to Grand Cayman in December is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated November 10, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,012 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,045 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Grand Cayman?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Grand Cayman. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How long is the flight from St. Louis to Grand Cayman?

    For as low as $338, Delta can have you in Grand Cayman from St. Louis in 5h 40m. Airlines will cover a distance of 1448 mi.

  • Can I find deals for flights from St. Louis to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on St. Louis to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Grand Cayman.

  • Can I find deals for business class flights from St. Louis to Grand Cayman?

    Yes. Cheapflights offers flight deals from St. Louis to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Grand Cayman?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Grand Cayman (average of $267). Flying from St. Louis to Grand Cayman in December is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for St. Louis to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Kansas City to George Town flights
St. Louis to George Town flights

Top 4 airlines flying from St. Louis to Grand Cayman

Discover the top 4 airlines that operate flights from St. Louis to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$266Average$613FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$607FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$429Average$581FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$469Average$698FlexibilityNo cancel feeOn-time69%

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