$457+ Cheap flights from Missouri to Grand Cayman
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Jun 21 — Jun 281
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Grand Cayman
Keep the following information in mind while searching for Missouri to Grand Cayman flight deals. Data was last updated June 16, 2025.
Round-trip from | $457 (American Airlines) |
|---|---|
Popular in | December |
Cheapest in | July |
Average price | $589 |
Find flight deals from Missouri to Grand Cayman
Cheapest flights from Missouri to Grand CaymanExplore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.
Explore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:00 pmSTL - GCM
1 stop16h 05mAmerican Airlines
Sat 10/253:20 pmGCM - STL
1 stop7h 49mAmerican Airlines
Deal found 6/14![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/303:00 pmMCI - GCM
2 stops20h 10mAmerican Airlines
Sat 9/1312:10 pmGCM - MCI
1 stop11h 49mAmerican Airlines
Deal found 6/15![American Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/146:00 amSTL - GCM
1 stop5h 22mDelta
Thu 7/2412:37 pmGCM - STL
1 stop9h 05mDelta
Deal found 6/15![Delta logo]()
$484
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/175:00 amSTL - GCM
1 stop6h 50mSouthwest
Fri 7/2512:45 pmGCM - STL
1 stop10h 40mSouthwest
Deal found 6/14![Southwest logo]()
$550
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:30 amMCI - GCM
2 stops53h 00mUnited Airlines
Sun 10/264:40 pmGCM - MCI
2 stops29h 10mUnited Airlines
Deal found 6/14![United Airlines logo]()
$569
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/126:33 amSTL - GCM
1 stop6h 57mUnited Airlines
Thu 7/241:35 pmGCM - STL
1 stop8h 40mUnited Airlines
Deal found 6/15![United Airlines logo]()
$574
This Mytrip deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2311:24 amSTL - GCM
3 stops33h 56mMultiple Airlines
Wed 7/3011:30 amGCM - STL
3 stops31h 11mMultiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$640
This Mytrip deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/16:05 amMCI - GCM
3 stops34h 05mMultiple Airlines
Wed 7/911:30 amGCM - MCI
3 stops22h 05mMultiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$663
This FlightHub deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/139:15 amSTL - GCM
1 stop26h 40mAir Canada
Mon 7/2112:50 pmGCM - STL
1 stop26h 26mAir Canada
Deal found 6/15![Air Canada logo]()
$3,616
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from Missouri to Grand Cayman that are best for you.
Fly from
Missouri
Fly to
Grand Cayman
Route
Depart
Return
Price
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 10/18
7:00 pm-11:05 am
1 stop16h 05m
George Town Owen Roberts Intl
Sat 10/25
3:20 pm-11:09 pm
1 stop7h 49m
$457
Kansas CityGeorge Town
MCI - GCM
MCIGCM
Kansas City
Sat 8/30
3:00 pm-11:10 am
2 stops20h 10m
George Town Owen Roberts Intl
Sat 9/13
12:10 pm-11:59 pm
1 stop11h 49m
$461
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Mon 7/14
6:00 am-11:22 am
1 stop5h 22m
George Town Owen Roberts Intl
Thu 7/24
12:37 pm-9:42 pm
1 stop9h 05m
$484
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Thu 7/17
5:00 am-11:50 am
1 stop6h 50m
George Town Owen Roberts Intl
Fri 7/25
12:45 pm-11:25 pm
1 stop10h 40m
$550
Kansas CityGeorge Town
MCI - GCM
MCIGCM
Kansas City
Thu 10/23
7:30 am-12:30 pm
2 stops53h 00m
George Town Owen Roberts Intl
Sun 10/26
4:40 pm-9:50 pm
2 stops29h 10m
$569
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 7/12
6:33 am-1:30 pm
1 stop6h 57m
George Town Owen Roberts Intl
Thu 7/24
1:35 pm-10:15 pm
1 stop8h 40m
$574
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 7/23
11:24 am-9:20 pm
3 stops33h 56m
George Town Owen Roberts Intl
Wed 7/30
11:30 am-6:41 pm
3 stops31h 11m
$640
Kansas CityGeorge Town
MCI - GCM
MCIGCM
Kansas City
Tue 7/1
6:05 am-4:10 pm
3 stops34h 05m
George Town Owen Roberts Intl
Wed 7/9
11:30 am-9:35 am
3 stops22h 05m
$663
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 7/13
9:15 am-11:55 am
1 stop26h 40m
George Town Owen Roberts Intl
Mon 7/21
12:50 pm-3:16 pm
1 stop26h 26m
$3,616
Best time to book a flight from Missouri to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Grand Cayman
What is the cheapest month to book a flight from Missouri to Grand Cayman?
Currently, January is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $467). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to LAW?
Find hourly flight availability from Missouri to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Grand Cayman as you normally would.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated June 16, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Missouri to Grand Cayman. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.6
Overall
8.0
Boarding
8.2
Food
7.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Crew
8.6
Entertainment
7.6
Overall
8.0
Boarding
8.2
Food
7.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Crew
8.6
Entertainment
7.6
Overall
8.0
Boarding
8.2
Food
7.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Crew
8.6
Entertainment
7.6
Overall
8.0
Boarding
8.2
Food
7.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Crew
8.6
Entertainment
7.6
Overall
8.0
Boarding
8.2
Food
7.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Crew
8.6
Entertainment
7.6
Overall
8.0
Boarding
8.2
Food
7.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Related info for your journey
Find useful and relevant information for your journey from Missouri to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Missouri to Grand Cayman
Discover the top 4 airlines that operate flights from Missouri to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$603 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$266 | Average$598 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$434 | Average$602 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$483 | Average$619 | FlexibilityNo cancel fee | On-time63% |