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Grand Cayman

$367+ Cheap flights from Missouri to Grand Cayman

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
dic. 26 — ene. 21
vie. 12/26
vie. 1/2
1 adult, Economy
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Find flight deals from Missouri to Grand Cayman

Cheapest flights from Missouri to Grand Cayman
Explore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 26, 2025.

This Delta deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:00 amSTL - GCM
1 stop5h 36mDelta
mié. 12/313:42 pmGCM - STL
1 stop8h 56mDelta
Deal found 11/26$367
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:42 pmSTL - GCM
2 stops20h 38mUnited Airlines
lun. 12/155:45 pmGCM - STL
1 stop17h 19mUnited Airlines
Deal found 11/24$414
This Kiwi.com deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1911:13 amMCI - GCM
2 stops28h 42mMultiple Airlines
sáb. 12/275:56 pmGCM - MCI
1 stop24h 14mMultiple Airlines
Deal found 11/26$442
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:30 amSTL - GCM
2 stops29h 35mAmerican Airlines
mié. 12/3112:55 pmGCM - STL
1 stop7h 35mAmerican Airlines
Deal found 11/26$442
This Delta deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:00 amSTL - GCM
1 stop5h 36mDelta
mar. 12/301:52 pmGCM - STL
1 stop10h 50mDelta
Deal found 11/26$477
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/238:00 amMCI - GCM
1 stop5h 27mDelta
jue. 1/11:52 pmGCM - MCI
1 stop6h 46mDelta
Deal found 11/25$484
This Kiwi.com deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/196:15 pmMCI - GCM
1 stop21h 40mSpirit Airlines
sáb. 12/275:56 pmGCM - MCI
1 stop24h 14mSpirit Airlines
Deal found 11/26$501
This Delta deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/165:50 amMCI - GCM
1 stop5h 50mDelta
dom. 12/213:42 pmGCM - MCI
1 stop9h 14mDelta
Deal found 11/26$509
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/215:43 amMCI - GCM
1 stop5h 53mDelta
vie. 12/263:42 pmGCM - MCI
1 stop9h 14mDelta
Deal found 11/24$510
This United Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/198:09 amMCI - GCM
1 stop6h 51mUnited Airlines
vie. 12/265:10 pmGCM - MCI
2 stops17h 08mUnited Airlines
Deal found 11/26$514
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/115:50 amMCI - GCM
1 stop5h 45mDelta
mar. 12/161:55 pmGCM - MCI
1 stop8h 13mDelta
Deal found 11/24$525
This Southwest deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:50 pmMCI - GCM
2 stops16h 45mSouthwest
mar. 12/161:30 pmGCM - MCI
2 stops10h 00mSouthwest
Deal found 11/24$530

Cheap flight deals from Missouri to Grand Cayman

Keep the following information in mind while searching for Missouri to Grand Cayman flight deals. Data was last updated noviembre 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$306
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$544
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
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From Missouri to Grand Cayman
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
Use the filters below to find and compare flights from Missouri to Grand Cayman that are best for you.

Fly from

Missouri

Fly to

Grand Cayman

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

mar. 2/3

2:05 pm-11:37 pm

1 stop10h 32m

$376

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 2/23

6:00 am-12:29 pm

1 stop5h 29m

George Town Owen Roberts Intl

jue. 2/26

1:54 pm-8:41 pm

1 stop7h 47m

$376

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

mié. 2/4

2:05 pm-8:37 pm

1 stop7h 32m

$376

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 2/23

6:00 am-8:16 pm

2 stops13h 16m

George Town Owen Roberts Intl

jue. 2/26

4:25 pm-8:52 am

1 stop17h 27m

$381

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

jue. 3/5

11:19 am-8:16 pm

1 stop7h 57m

George Town Owen Roberts Intl

jue. 3/12

7:45 am-5:40 pm

1 stop9h 55m

$406

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

sáb. 1/31

7:10 am-2:00 pm

1 stop5h 50m

George Town Owen Roberts Intl

mié. 2/4

2:05 pm-8:37 pm

1 stop7h 32m

$406

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

sáb. 1/31

2:05 pm-7:27 pm

1 stop6h 22m

$406

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

lun. 2/2

2:05 pm-11:37 pm

1 stop10h 32m

$406

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

vie. 1/30

5:32 pm-12:50 pm

1 stop18h 18m

George Town Owen Roberts Intl

mar. 2/3

2:05 pm-8:37 pm

1 stop7h 32m

$406

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

sáb. 1/31

6:00 am-2:00 pm

1 stop7h 00m

George Town Owen Roberts Intl

mar. 2/3

2:05 pm-8:37 pm

1 stop7h 32m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Showing 1-10 of 23 results
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Best time to book a flight from Missouri to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Grand Cayman

What is the cheapest month to book a flight from Missouri to Grand Cayman?

Currently, May is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $239). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to LAW?

Find hourly flight availability from Missouri to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 26, 2025.

It’s optimal to fly from Missouri to Grand Cayman at noon. By choosing this option you can save up to 26% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Grand Cayman?

    Departing from Missouri to Grand Cayman will take you 5h 40m. There are 1448 mi between Missouri and Grand Cayman. This flight may include one or multiple stops.

  • Can I find deals for flights from Missouri to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Missouri to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Grand Cayman.

  • Can I find deals for business class flights from Missouri to Grand Cayman?

    Yes. Cheapflights offers flight deals from Missouri to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Grand Cayman?

    Currently, May is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $239). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Grand Cayman

Discover the top 4 airlines that operate flights from Missouri to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$238Average$630FlexibilityNo cancel feeOn-time69%
DeltaCheapest$266Average$588FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$579FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$429Average$636FlexibilityNo cancel feeOn-time63%

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