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Grand Cayman

$394+ Cheap flights from Missouri to Grand Cayman

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
ago. 11 — ago. 181
lun. 8/11
lun. 8/18
1 adult, Economy
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Cheap flight deals from Missouri to Grand Cayman

Keep the following information in mind while searching for Missouri to Grand Cayman flight deals. Data was last updated agosto 6, 2025.

Round-trip from

$394
(American Airlines)

Popular in

August

Cheapest in

July

Average price

$655
From Missouri to Grand Cayman
Search Deals
High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Missouri to Grand Cayman

Cheapest flights from Missouri to Grand Cayman
Explore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 6, 2025.

This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/35:28 amSTL - GCM
1 stop5h 42mAmerican Airlines
mié. 9/1012:10 pmGCM - STL
1 stop11h 49mAmerican Airlines
Deal found 8/6$394
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/265:28 amSTL - GCM
1 stop5h 42mAmerican Airlines
jue. 10/212:10 pmGCM - STL
1 stop11h 49mAmerican Airlines
Deal found 8/4$424
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/272:11 pmSTL - GCM
2 stops20h 59mAmerican Airlines
sáb. 10/1112:10 pmGCM - STL
2 stops11h 08mAmerican Airlines
Deal found 8/6$428
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/184:25 pmSTL - GCM
1 stop19h 00mAmerican Airlines
sáb. 10/258:25 amGCM - STL
2 stops13h 41mAmerican Airlines
Deal found 8/6$436
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:28 amSTL - GCM
1 stop5h 42mAmerican Airlines
lun. 9/2912:10 pmGCM - STL
1 stop11h 49mAmerican Airlines
Deal found 8/6$454
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/237:16 amSTL - GCM
2 stops12h 04mAmerican Airlines
mié. 10/2912:10 pmGCM - STL
2 stops11h 08mAmerican Airlines
Deal found 8/6$468
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/305:21 amSTL - GCM
1 stop5h 37mAmerican Airlines
vie. 12/55:35 pmGCM - STL
1 stop6h 59mAmerican Airlines
Deal found 8/6$511
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/296:00 amSTL - GCM
1 stop5h 56mAmerican Airlines
vie. 12/58:30 amGCM - STL
1 stop15h 35mAmerican Airlines
Deal found 8/6$520
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/35:06 amMCI - GCM
1 stop6h 04mAmerican Airlines
vie. 10/1012:10 pmGCM - MCI
1 stop10h 49mAmerican Airlines
Deal found 8/6$536
This Mytrip deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/52:55 pmMCI - GCM
2 stops25h 10mMultiple Airlines
vie. 9/127:00 amGCM - MCI
3 stops32h 10mMultiple Airlines
Deal found 8/6$611
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/235:00 amMCI - GCM
1 stop10h 00mAmerican Airlines
jue. 1/14:15 pmGCM - MCI
1 stop8h 50mAmerican Airlines
Deal found 8/6$636
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/225:05 amMCI - GCM
1 stop14h 15mAmerican Airlines
mié. 11/268:30 amGCM - MCI
1 stop16h 29mAmerican Airlines
Deal found 8/5$671

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 6, 2025.
Use the filters below to find and compare flights from Missouri to Grand Cayman that are best for you.

Fly from

Missouri

Fly to

Grand Cayman

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

mié. 9/3

5:28 am-11:10 am

1 stop5h 42m

George Town Owen Roberts Intl

mié. 9/10

12:10 pm-11:59 pm

1 stop11h 49m

$394

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

vie. 9/26

5:28 am-11:10 am

1 stop5h 42m

George Town Owen Roberts Intl

jue. 10/2

12:10 pm-11:59 pm

1 stop11h 49m

$424

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

sáb. 9/27

2:11 pm-11:10 am

2 stops20h 59m

George Town Owen Roberts Intl

sáb. 10/11

12:10 pm-11:18 pm

2 stops11h 08m

$428

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

sáb. 10/18

4:25 pm-11:25 am

1 stop19h 00m

George Town Owen Roberts Intl

sáb. 10/25

8:25 am-11:18 pm

2 stops14h 53m

$436

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

jue. 9/18

6:01 am-11:36 am

1 stop5h 35m

George Town Owen Roberts Intl

jue. 9/25

12:52 pm-9:15 pm

1 stop8h 23m

$454

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

jue. 9/18

6:00 pm-11:25 am

2 stops17h 25m

George Town Owen Roberts Intl

jue. 9/25

12:28 pm-7:20 pm

1 stop6h 52m

$458

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

lun. 10/6

5:23 am-1:10 pm

1 stop7h 47m

George Town Owen Roberts Intl

dom. 10/12

8:25 am-11:56 pm

1 stop15h 31m

$459

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

jue. 10/23

7:16 am-7:20 pm

2 stops12h 04m

George Town Owen Roberts Intl

mié. 10/29

12:10 pm-11:18 pm

2 stops11h 08m

$468

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

vie. 10/3

5:06 am-11:10 am

1 stop6h 04m

George Town Owen Roberts Intl

vie. 10/10

12:10 pm-10:59 pm

1 stop10h 49m

$536

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

sáb. 1/31

5:43 am-12:56 pm

1 stop6h 13m

George Town Owen Roberts Intl

sáb. 2/7

4:40 pm-11:36 am

1 stop19h 56m

$544

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/5

Showing 1-10 of 14 results
1
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Best time to book a flight from Missouri to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Grand Cayman

What is the cheapest month to book a flight from Missouri to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $467). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to LAW?

Find hourly flight availability from Missouri to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 6, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Grand Cayman as you normally would.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated agosto 6, 2025.
See what other customers who have flown with Delta and American Airlines from Missouri to Grand Cayman have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,985 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,985 reviews
Delta
8.0
Very good
7,985 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,985 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Missouri to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Missouri to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Grand Cayman.

  • Can I find deals for business class flights from Missouri to Grand Cayman?

    Yes. Cheapflights offers flight deals from Missouri to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $467). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Missouri to Grand Cayman

Discover the top 4 airlines that operate flights from Missouri to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$238Average$602FlexibilityNo cancel feeOn-time69%
DeltaCheapest$266Average$584FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$429Average$610FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$434Average$605FlexibilityNo cancel feeOn-time71%

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