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$379+ Cheap flights from Panama City, FL (ECP) to Frankfurt (FRA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — FRA
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Panama City to Frankfurt

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Frankfurt (FRA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$1,802
(United Airlines)

One-way from

$379
(Delta)

Popular in

July

Cheapest in

March

Average price

$986
From Panama City NW Florida Beaches to Frankfurt am Main
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One-way flight from Panama City NW Florida Beaches to Frankfurt am Main
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Highest demand for flights based on searches. 9% potential increase in price ($119 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($52 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Frankfurt

Cheapest flights from Panama City to Frankfurt
Explore the most affordable flight options available from Panama City to Frankfurt. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/204:45 pmECP - FRA
2 stops30h 50mUnited Airlines
vie. 1/28:40 amFRA - ECP
2 stops31h 37mUnited Airlines
Deal found 9/10$1,802
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/2011:11 amECP - FRA
1 stop14h 39mAmerican Airlines
vie. 1/210:15 amFRA - ECP
1 stop18h 09mAmerican Airlines
Deal found 9/10$1,817
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/191:32 pmECP - FRA
1 stop12h 08mDelta
mié. 12/179:40 amFRA - ECP
2 stops19h 58mDelta
Deal found 9/10$3,561
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/196:47 amECP - FRA
1 stop17h 28mAmerican Airlines
mié. 12/1710:15 amFRA - ECP
1 stop16h 31mAmerican Airlines
Deal found 9/11$4,075
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/196:30 amECP - FRA
2 stops16h 30mUnited Airlines
mié. 12/175:10 pmFRA - ECP
2 stops27h 17mUnited Airlines
Deal found 9/10$4,615

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Frankfurt that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Panama City to Frankfurt am Main Airport that are best for you.

Fly from

Panama City

Fly to

Frankfurt

Route

Depart

Return

Price

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

sáb. 12/20

4:45 pm-6:35 am

2 stops30h 50m

Frankfurt am Main

vie. 1/2

8:40 am-9:17 am

2 stops31h 37m

$1,802

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

sáb. 12/20

11:11 am-8:50 am

1 stop14h 39m

Frankfurt am Main

vie. 1/2

10:15 am-9:24 pm

1 stop18h 09m

$1,817

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

mié. 11/19

1:32 pm-8:40 am

1 stop12h 08m

Frankfurt am Main

mié. 12/17

9:40 am-10:38 pm

2 stops19h 58m

$3,561

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

mié. 11/19

6:47 am-7:15 am

1 stop17h 28m

Frankfurt am Main

mié. 12/17

10:15 am-7:46 pm

1 stop16h 31m

$4,075

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

mié. 11/19

6:30 am-6:00 am

2 stops16h 30m

Frankfurt am Main

mié. 12/17

5:10 pm-1:27 pm

2 stops27h 17m

$4,615

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

mar. 11/25

9:20 am-8:40 am

1 stop16h 20m

$379

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

lun. 11/24

7:02 am-8:40 am

1 stop18h 38m

$379

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

dom. 11/23

4:26 pm-8:40 am

1 stop33h 14m

$390

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

mar. 11/25

7:15 am-7:15 am

2 stops17h 00m

$673

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

dom. 11/23

7:15 am-8:50 am

1 stop18h 35m

$673

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama City to Frankfurt

Have a flexible travel schedule? Discover the best time to fly to Frankfurt from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Frankfurt am Main Airport

What is the cheapest month to book a flight from Panama City, Florida to Frankfurt am Main Airport?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Frankfurt am Main Airport (average of $729). Flying from Panama City, Florida to Frankfurt am Main Airport in June is currently the most expensive (average of $1,091). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to FRA?

Find hourly flight availability from Panama City to Frankfurt. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 22% on flights from Panama City, Florida to Frankfurt am Main Airport by exploring options for tickets in the afternoon.

Reviews of airlines servicing Frankfurt

Get insights into the airlines that provide service to Frankfurt. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Frankfurt. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with American Airlines from Panama City to Frankfurt am Main Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Frankfurt. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Frankfurt am Main?

    Most people fly from Panama City NW Florida Beaches (ECP) if they book a flight from Panama City to Frankfurt am Main. On average, NW Florida Beaches has 0 outbound flights to Frankfurt am Main per day from 1 airline. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Frankfurt am Main Airport?

    Airlines like United Airlines, American Airlines, and Delta fly from Panama City, Florida to Frankfurt am Main Airport in about 12h 08m. The time it takes to get you to your destination can typically vary by up to 18h 42m. The distance between Panama City, Florida and Frankfurt am Main Airport is about 4819 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City, Florida to Frankfurt am Main Airport round-trip?

    American Airlines, at $986, was found to be the cheapest airline from Panama City, Florida to Frankfurt am Main Airport.. Users have found that American Airlines is 11% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Frankfurt that include hotel bookings?

    Yes. In addition to deals on Panama City to Frankfurt flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Frankfurt?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Frankfurt.

  • Can I find deals for business class flights from Panama City to Frankfurt?

    Yes. Cheapflights offers flight deals from Panama City to Frankfurt by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Frankfurt am Main Airport?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Frankfurt am Main Airport (average of $729). Flying from Panama City, Florida to Frankfurt am Main Airport in June is currently the most expensive (average of $1,091). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Frankfurt am Main Airport?

Book flights to Frankfurt am Main Airport if you plan to visit one of these locations
Koblenz
Baden-Baden
Wurzburg
Wiesbaden
Speyer
Trier
Boppard
Mainz

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Frankfurt

Discover the top airline that operate flights from Panama City to Frankfurt. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$986Average$1,237FlexibilityNo cancel feeOn-time71%

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