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$212+ Cheap flights from Santo Domingo (SDQ) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Santo Domingo to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$300
(Kiwi.com)

One-way from

$212
(Mytrip)

Popular in

January

Cheapest in

February

Average price

$482
From Santo Domingo Las Americas to Charleston
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One-way flight from Santo Domingo Las Americas to Charleston
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Highest demand for flights based on searches. 15% potential increase in price ($113 potential increase over avg. RT price).
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Cheapest flight prices on average. 13% potential price decrease ($73 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santo Domingo to Charleston

Cheapest flights from Santo Domingo to Charleston
Explore the most affordable flight options available from Santo Domingo to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:54 pmSDQ - CHS
1 stop17h 12mSpirit Airlines
Fri 11/75:40 pmCHS - SDQ
1 stop23h 10mSpirit Airlines
Deal found 9/10$300
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:18 amSDQ - CHS
2 stops26h 48mMultiple Airlines
Fri 11/75:40 pmCHS - SDQ
1 stop23h 10mMultiple Airlines
Deal found 9/10$352
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:25 amSDQ - CHS
2 stops10h 18mAmerican Airlines
Sun 12/76:00 amCHS - SDQ
1 stop5h 28mAmerican Airlines
Deal found 9/11$410
This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:20 pmSDQ - CHS
1 stop18h 10mUnited Airlines
Sun 12/76:00 amCHS - SDQ
1 stop16h 46mUnited Airlines
Deal found 9/11$417
This SmartFares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:12 amSDQ - CHS
1 stop10h 07mJetBlue
Thu 10/305:20 pmCHS - SDQ
1 stop19h 57mJetBlue
Deal found 9/10$420
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:05 pmSDQ - CHS
1 stop17h 40mSpirit Airlines
Sun 9/2112:08 pmCHS - SDQ
1 stop27h 52mSpirit Airlines
Deal found 9/11$427
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:35 amSDQ - CHS
1 stop12h 10mJetBlue
Fri 10/312:15 pmCHS - SDQ
1 stop9h 34mJetBlue
Deal found 9/10$437

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Santo Domingo

Fly to

Charleston

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 10/16

3:54 pm-9:06 am

1 stop17h 12m

Charleston

Fri 11/7

5:40 pm-5:50 pm

1 stop23h 10m

$300

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 10/16

6:18 am-9:06 am

2 stops26h 48m

Charleston

Fri 11/7

5:40 pm-5:50 pm

1 stop23h 10m

$352

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 10/7

10:25 am-8:43 pm

2 stops10h 18m

Charleston

Sun 12/7

6:00 am-12:28 pm

1 stop5h 28m

$410

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 10/7

3:20 pm-9:30 am

1 stop18h 10m

Charleston

Sun 12/7

6:00 am-11:46 pm

1 stop16h 46m

$417

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 2/5

2:53 pm-11:45 pm

1 stop9h 52m

Charleston

Sat 2/7

2:30 pm-11:46 pm

1 stop8h 16m

$419

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 10/30

5:35 am-1:19 pm

1 stop7h 44m

Charleston

Thu 10/30

5:20 pm-1:17 pm

1 stop19h 57m

$420

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 9/29

5:35 am-5:45 pm

1 stop12h 10m

Charleston

Fri 10/31

2:15 pm-11:49 pm

1 stop9h 34m

$437

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 10/20

5:12 pm-6:41 pm

2 stops25h 29m

$212

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 10/20

6:05 am-5:51 pm

1 stop11h 46m

$216

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 12/22

6:51 pm-12:45 am

1 stop6h 54m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 15 results
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Best time to book a flight from Santo Domingo to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Charleston

What is the cheapest time of day to fly from SDQ to CHS?

Find hourly flight availability from Santo Domingo to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Santo Domingo to Charleston, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 33% versus a flight in the morning.

How much does it cost to fly round-trip from Santo Domingo to Charleston?

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Charleston?

    A quick flight from Santo Domingo to Charleston can take about 10h 18m. Spirit Airlines provides one of the quickest options available for as low as $410. Santo Domingo and Charleston are separated by a distance of 1187 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Santo Domingo to Charleston one-way?

    The cheapest airlines for a one-way flight from Santo Domingo to Charleston are Spirit Airlines ($212), Delta ($216), and American Airlines ($222).

  • Can I find deals for flights from Santo Domingo to Charleston that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Charleston.

  • Can I find deals for business class flights from Santo Domingo to Charleston?

    Yes. Cheapflights offers flight deals from Santo Domingo to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to Charleston (average of $217). Flying from Santo Domingo to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Santee
Edisto Beach

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