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$167+ Cheap flights from Santo Domingo (SDQ) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Santo Domingo to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$339
(Delta)

One-way from

$167
(Kiwi.com)

Popular in

January

Cheapest in

February

Average price

$557
Provider with most accurate pricing for Santo Domingo Las Americas-Charleston flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Charleston flights.
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From Santo Domingo Las Americas to Charleston
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One-way flight from Santo Domingo Las Americas to Charleston
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Highest demand for flights based on searches. 19% potential increase in price ($142 potential increase over avg. RT price).
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Cheapest flight prices on average. 14% potential price decrease ($75 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Santo Domingo to Charleston

Cheapest flights from Santo Domingo to Charleston
Explore the most affordable flight options available from Santo Domingo to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/232:52 pmSDQ - CHS
2 stops27h 26mMultiple Airlines
Wed 12/36:15 pmCHS - SDQ
1 stop10h 10mMultiple Airlines
Deal found 10/27$430
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:35 pmSDQ - CHS
2 stops15h 51mSpirit Airlines
Sat 11/296:50 amCHS - SDQ
1 stop7h 40mSpirit Airlines
Deal found 10/27$462
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:01 amSDQ - CHS
1 stop11h 04mDelta
Sat 11/298:00 amCHS - SDQ
1 stop5h 42mDelta
Deal found 10/27$463
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/234:35 pmSDQ - CHS
3 stops25h 43mSpirit Airlines
Wed 12/36:15 pmCHS - SDQ
2 stops20h 08mSpirit Airlines
Deal found 10/27$501
This SmartFares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:10 amSDQ - CHS
1 stop9h 42mJetBlue
Wed 12/39:46 amCHS - SDQ
1 stop27h 36mJetBlue
Deal found 10/27$551
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:35 pmSDQ - CHS
3 stops25h 28mMultiple Airlines
Sat 11/296:50 amCHS - SDQ
2 stops16h 55mMultiple Airlines
Deal found 10/27$626
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/214:09 amSDQ - CHS
1 stop13h 39mJetBlue
Sat 11/298:30 pmCHS - SDQ
1 stop5h 00mJetBlue
Deal found 10/27$651

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Santo Domingo

Fly to

Charleston

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 2/5

7:31 am-5:13 pm

1 stop10h 42m

Charleston

Sat 2/7

5:25 am-2:21 pm

1 stop7h 56m

$339

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sun 11/23

2:52 pm-5:18 pm

2 stops27h 26m

Charleston

Wed 12/3

6:15 pm-5:25 am

1 stop10h 10m

$430

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sat 11/22

4:35 pm-7:26 am

2 stops15h 51m

Charleston

Sat 11/29

6:50 am-3:30 pm

1 stop7h 40m

$462

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sat 11/22

7:01 am-5:05 pm

1 stop11h 04m

Charleston

Sat 11/29

8:00 am-2:42 pm

1 stop5h 42m

$463

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 12/5

6:35 am-7:08 pm

2 stops13h 33m

$176

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 12/2

6:35 am-7:08 pm

2 stops13h 33m

$176

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 11/10

8:40 pm-1:25 pm

2 stops17h 45m

$176

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 12/4

8:43 pm-1:23 pm

2 stops17h 40m

$176

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 12/3

6:35 am-5:24 pm

2 stops11h 49m

$176

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 11/12

6:45 am-8:42 pm

2 stops14h 57m

$176

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 13 results
1
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Compare providers for flights from Santo Domingo to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Charleston in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Charleston

What is the cheapest time of day to fly from SDQ to CHS?

Find hourly flight availability from Santo Domingo to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

When flying from Santo Domingo to Charleston, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 32% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Charleston?

    A quick flight from Santo Domingo to Charleston can take about 10h 42m. Delta provides one of the quickest options available for as low as $339. Santo Domingo and Charleston are separated by a distance of 1187 mi.

  • Can I find deals for flights from Santo Domingo to Charleston that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Charleston.

  • Can I find deals for business class flights from Santo Domingo to Charleston?

    Yes. Cheapflights offers flight deals from Santo Domingo to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Isle of Palms
Santee
Mount Pleasant
Edisto Beach

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