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$164+ Cheap flights from Santo Domingo (SDQ) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
ago. 4 — ago. 111
lun. 8/4
lun. 8/11
1 adult, Economy
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Cheap flight deals from Santo Domingo to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 30, 2025.

Round-trip from

$434
(Mytrip)

One-way from

$164
(SmartFares)

Popular in

January

Cheapest in

February

Average price

$471
From Santo Domingo Las Americas to Charleston
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One-way flight from Santo Domingo Las Americas to Charleston
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Highest demand for flights based on searches. 14% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 13% potential price decrease ($72 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santo Domingo to Charleston

Cheapest flights from Santo Domingo to Charleston
Explore the most affordable flight options available from Santo Domingo to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/125:05 pmSDQ - CHS
2 stops22h 19mMultiple Airlines
vie. 9/1910:31 amCHS - SDQ
1 stop5h 29mMultiple Airlines
Deal found 7/29$434
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/121:45 pmSDQ - CHS
1 stop8h 31mDelta
vie. 9/196:20 amCHS - SDQ
1 stop7h 04mDelta
Deal found 7/29$466
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/206:00 amSDQ - CHS
2 stops11h 27mAmerican Airlines
dom. 1/1111:09 amCHS - SDQ
2 stops10h 41mAmerican Airlines
Deal found 7/29$617
This Trip.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/193:45 amSDQ - CHS
1 stop8h 36mJetBlue
dom. 1/116:19 pmCHS - SDQ
1 stop8h 35mJetBlue
Deal found 7/29$747

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Santo Domingo

Fly to

Charleston

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 9/12

5:05 pm-3:24 pm

2 stops22h 19m

Charleston

vie. 9/19

10:31 am-4:00 pm

1 stop5h 29m

$434

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 9/12

1:45 pm-10:16 pm

1 stop8h 31m

Charleston

vie. 9/19

6:20 am-1:24 pm

1 stop7h 04m

$466

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

jue. 11/20

6:00 am-4:27 pm

2 stops11h 27m

Charleston

dom. 1/11

11:09 am-10:50 pm

2 stops10h 41m

$617

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mié. 11/19

3:45 am-11:21 am

1 stop8h 36m

Charleston

dom. 1/11

6:19 pm-3:54 am

1 stop8h 35m

$747

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

sáb. 9/20

3:47 pm-11:05 am

1 stop19h 18m

$164

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mar. 8/19

5:05 pm-8:37 am

2 stops39h 32m

$199

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 9/19

6:03 am-8:48 pm

2 stops14h 45m

$250

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 8/15

6:05 am-8:45 am

1 stop26h 40m

$291

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

dom. 8/31

7:05 am-7:00 pm

1 stop11h 55m

$331

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Santo Domingo to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Charleston

What is the cheapest time of day to fly from SDQ to CHS?

Find hourly flight availability from Santo Domingo to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 30, 2025.

When flying from Santo Domingo to Charleston, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 33% versus a flight in the morning.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated julio 30, 2025.
Peruse reviews from past customers who have flown with Delta, JetBlue, and American Airlines from Santo Domingo to Charleston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
JetBlue
7.3
Good
2,913 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Spirit Airlines
6.3
Okay
8,048 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Charleston round-trip?

    Our cheapest airline available from Santo Domingo to Charleston is Delta. Our recent data shows that you can find tickets from as low as $466 on this airline. Additional options worth looking into are American Airlines and JetBlue, starting at $617 and $747 round-trip. Users have found that Delta is 24% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Santo Domingo to Charleston one-way?

    The cheapest airlines for a one-way flight from Santo Domingo to Charleston are Spirit Airlines ($164), Delta ($250), and JetBlue ($291).

  • Can I find deals for flights from Santo Domingo to Charleston that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Charleston.

  • Can I find deals for business class flights from Santo Domingo to Charleston?

    Yes. Cheapflights offers flight deals from Santo Domingo to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to Charleston (average of $217). Flying from Santo Domingo to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Santee
Edisto Beach

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Top airline flying from Santo Domingo to Charleston

Discover the top airline that operate flights from Santo Domingo to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$264Average$438FlexibilityNo cancel feeOn-timeN/A

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