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$184+ Cheap flights from Santo Domingo (SDQ) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Santo Domingo to Charleston

Best flights from Santo Domingo to Charleston
Discover carefully curated flight deals from Santo Domingo to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 12, 2025.

This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/57:00 amSDQ - CHS
1 stop9h 44mDelta
jue. 5/146:00 amCHS - SDQ
1 stop12h 18mDelta
Deal found 12/11$325
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/17:55 amSDQ - CHS
1 stop14h 47mAmerican Airlines
lun. 5/48:08 pmCHS - SDQ
1 stop14h 42mAmerican Airlines
Deal found 12/10$344
This JetBlue deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/28:59 pmSDQ - CHS
1 stop13h 16mJetBlue
jue. 5/149:15 pmCHS - SDQ
1 stop13h 52mJetBlue
Deal found 12/11$347
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/294:18 pmSDQ - CHS
1 stop8h 26mUnited Airlines
lun. 2/26:00 amCHS - SDQ
1 stop8h 06mUnited Airlines
Deal found 12/9$418
This Expedia deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/13:01 pmSDQ - CHS
1 stop25h 34mJetBlue
jue. 5/149:15 pmCHS - SDQ
1 stop13h 52mJetBlue
Deal found 12/11$397
This Trip.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/155:01 amSDQ - CHS
1 stop10h 44mJetBlue
lun. 5/258:00 pmCHS - SDQ
1 stop12h 49mJetBlue
Deal found 12/11$401
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/13:25 pmSDQ - CHS
1 stop7h 17mAmerican Airlines
jue. 5/147:40 amCHS - SDQ
1 stop14h 10mAmerican Airlines
Deal found 12/11$450
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/51:28 pmSDQ - CHS
2 stops10h 00mAmerican Airlines
jue. 5/147:40 amCHS - SDQ
1 stop12h 05mAmerican Airlines
Deal found 12/11$455
This JetBlue deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/299:50 pmSDQ - CHS
1 stop12h 30mJetBlue
lun. 2/210:10 amCHS - SDQ
1 stop9h 11mJetBlue
Deal found 12/10$421

Find flight deals from Santo Domingo to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$325
(Delta)

One-way from

$184
(American Airlines)

Popular in

April

Cheapest in

March

Average price

$473
Provider with most accurate pricing for Santo Domingo Las Americas-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Charleston flights.
Search Deals
From Santo Domingo Las Americas to Charleston
Search Deals
One-way flight from Santo Domingo Las Americas to Charleston
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Santo Domingo

Fly to

Charleston

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mar. 5/5

7:00 am-4:44 pm

1 stop9h 44m

Charleston

jue. 5/14

6:00 am-6:18 pm

1 stop12h 18m

$325

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 5/1

7:55 am-10:42 pm

1 stop14h 47m

Charleston

lun. 5/4

8:08 pm-10:50 am

1 stop14h 42m

$344

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

sáb. 5/2

8:59 pm-10:15 am

1 stop13h 16m

Charleston

jue. 5/14

9:15 pm-11:07 am

1 stop13h 52m

$347

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 5/1

3:01 pm-4:35 pm

1 stop25h 34m

Charleston

jue. 5/14

9:15 pm-11:07 am

1 stop13h 52m

$397

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 5/15

5:01 am-3:45 pm

1 stop10h 44m

Charleston

lun. 5/25

8:00 pm-8:49 am

1 stop12h 49m

$401

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

jue. 1/29

4:18 pm-11:44 pm

1 stop8h 26m

Charleston

lun. 2/2

6:00 am-3:06 pm

1 stop8h 06m

$418

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

jue. 1/29

9:50 pm-9:20 am

1 stop12h 30m

Charleston

lun. 2/2

10:10 am-8:21 pm

1 stop9h 11m

$421

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

vie. 5/1

3:25 pm-10:42 pm

1 stop7h 17m

Charleston

jue. 5/14

7:40 am-9:50 pm

1 stop14h 10m

$450

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mar. 5/5

1:28 pm-11:28 pm

2 stops10h 00m

Charleston

jue. 5/14

7:40 am-7:45 pm

1 stop12h 05m

$455

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mié. 5/27

11:30 am-12:13 am

1 stop12h 43m

$188

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 14 results
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Compare providers for flights from Santo Domingo to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Charleston in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Charleston

What is the cheapest time of day to fly from SDQ to CHS?

Find hourly flight availability from Santo Domingo to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

When flying from Santo Domingo to Charleston, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 32% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Charleston?

    A quick flight from Santo Domingo to Charleston can take about 9h 44m. Delta provides one of the quickest options available for as low as $325. Santo Domingo and Charleston are separated by a distance of 1187 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Santo Domingo to Charleston that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Charleston.

  • Can I find deals for business class flights from Santo Domingo to Charleston?

    Yes. Cheapflights offers flight deals from Santo Domingo to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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