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$300+ Cheap flights from Santa Fe to Charleston (SAF - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — CHS
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Santa Fe to Charleston

Cheapest flights from Santa Fe to Charleston
Explore the most affordable flight options available from Santa Fe to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:04 pm
SAF
-
CHS
1 stop6h 37m
American Airlines
Sat 5/27:00 am
CHS
-
SAF
1 stop7h 06m
American Airlines
Deal found 1/26$411
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:00 am
SAF
-
CHS
1 stop6h 05m
United Airlines
Sat 2/710:30 am
CHS
-
SAF
2 stops8h 26m
United Airlines
Deal found 1/25$565
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:25 am
SAF
-
CHS
1 stop6h 00m
American Airlines
Fri 2/137:05 am
CHS
-
SAF
1 stop7h 19m
American Airlines
Deal found 1/25$804

Find flight deals from Santa Fe to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$411
(American Airlines)

One-way from

$300
(United Airlines)
Provider with most accurate pricing for Santa Fe-Charleston flight deals.
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Provider most trusted by Cheapflights users for Santa Fe-Charleston flights.
Search Deals
From Santa Fe to Charleston
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One-way flight from Santa Fe to Charleston
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Santa Fe to Charleston that are best for you.

Fly from

Santa Fe

Fly to

Charleston

Route

Depart

Return

Price

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 4/28

2:04 pm-10:41 pm

1 stop6h 37m

Charleston

Sat 5/2

7:00 am-12:06 pm

1 stop7h 06m

$411

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Mon 2/9

6:25 am-2:25 pm

1 stop6h 00m

Charleston

Fri 2/13

7:05 am-12:24 pm

1 stop7h 19m

$804

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Mon 2/9

1:16 pm-2:48 pm

2 stops23h 32m

Charleston

Fri 2/13

5:05 pm-9:24 am

2 stops18h 19m

$819

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Sat 6/13

12:35 pm-10:54 pm

1 stop8h 19m

Charleston

Fri 6/19

1:06 pm-9:59 pm

2 stops10h 53m

$1,235

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 5/12

7:00 am-3:14 pm

1 stop6h 14m

$300

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Fri 5/8

2:04 pm-10:41 pm

1 stop6h 37m

$300

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 5/12

2:04 pm-10:41 pm

1 stop6h 37m

$300

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Mon 4/13

1:19 pm-9:37 pm

1 stop6h 18m

$300

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Sun 5/10

2:04 pm-10:41 pm

1 stop6h 37m

$300

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Mon 4/13

12:36 pm-10:41 pm

1 stop8h 05m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 12 results
1
2
  • Most accurate provider: When it comes to deals on Santa Fe-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Fe-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Fe to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Charleston

What is the cheapest month to book a flight from Santa Fe to Charleston?

Currently, September is the cheapest month in which you can book a flight from Santa Fe to Charleston (average of $248). Flying from Santa Fe to Charleston in February is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated January 27, 2026.
Read reviews from past customers who have flown American Airlines from Santa Fe to Charleston. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Overall

7.2

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Overall

7.2

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to Charleston?

    Airlines like American Airlines and United Airlines fly from Santa Fe to Charleston in about 6h 37m. The time it takes to get you to your destination can typically vary by up to 16h 55m. Santa Fe and Charleston are separated by a distance of 1494 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santa Fe to Charleston round-trip?

    According to our current data, American Airlines ($374), offers the cheapest pricing from Santa Fe to Charleston.

  • Can I find deals for flights from Santa Fe to Charleston that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Charleston.

  • Can I find deals for business class flights from Santa Fe to Charleston?

    Yes. Cheapflights offers flight deals from Santa Fe to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Charleston?

    Currently, September is the cheapest month in which you can book a flight from Santa Fe to Charleston (average of $248). Flying from Santa Fe to Charleston in February is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Santa Fe to Charleston

Discover the top airline that operate flights from Santa Fe to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$374Average$534FlexibilityNo cancel feeOn-time71%

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