Charleston

$122+ Cheap flights from Mesa, AZ to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — CHS
Oct 15 — Oct 221
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Find cheap flights from Mesa to Charleston with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Mesa to Charleston are usually found in January or February, booked 59 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Mesa to Charleston

Keep the following information in mind while searching for Mesa to Charleston flight deals. Data was last updated September 15, 2025.

Round-trip from

$194
(Kiwi.com)

One-way from

$122
(Trip.com)

Popular in

December

Cheapest in

January

Average price

$392
From Mesa to Charleston
One-way flight from Mesa to Charleston
Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Mesa to Charleston

Cheapest flights from Mesa to Charleston
Explore the most affordable flight options available from Mesa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1610:58 amPHX - CHS
1 stop19h 08mSpirit Airlines
Sun 10/1910:11 amCHS - PHX
1 stop26h 42mSpirit Airlines
Deal found 9/14$235
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:24 amPHX - CHS
1 stop21h 43mMultiple Airlines
Sun 11/210:11 amCHS - PHX
1 stop26h 42mMultiple Airlines
Deal found 9/14$237
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:30 amPHX - CHS
1 stop7h 20mAmerican Airlines
Tue 12/307:10 pmCHS - PHX
1 stop7h 24mAmerican Airlines
Deal found 9/12$243
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:00 amPHX - CHS
2 stops12h 14mMultiple Airlines
Sun 11/169:13 pmCHS - PHX
1 stop15h 11mMultiple Airlines
Deal found 9/14$258
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:41 pmPHX - CHS
1 stop22h 34mMultiple Airlines
Sun 10/1910:11 amCHS - PHX
1 stop26h 42mMultiple Airlines
Deal found 9/15$263
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:00 pmPHX - CHS
2 stops18h 47mMultiple Airlines
Sun 11/210:11 amCHS - PHX
1 stop26h 42mMultiple Airlines
Deal found 9/13$267
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:58 amPHX - CHS
1 stop19h 08mMultiple Airlines
Mon 11/39:56 amCHS - PHX
2 stops34h 54mMultiple Airlines
Deal found 9/13$270
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:24 pmPHX - CHS
1 stop30h 13mMultiple Airlines
Fri 10/317:05 amCHS - PHX
2 stops19h 54mMultiple Airlines
Deal found 9/14$277
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:59 pmPHX - CHS
1 stop9h 26mJetBlue
Wed 10/292:15 pmCHS - PHX
1 stop9h 42mJetBlue
Deal found 9/14$279
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:58 amPHX - CHS
1 stop19h 08mMultiple Airlines
Mon 10/1310:11 amCHS - PHX
2 stops28h 55mMultiple Airlines
Deal found 9/14$280
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:24 pmPHX - CHS
1 stop30h 13mMultiple Airlines
Mon 11/39:56 amCHS - PHX
2 stops34h 54mMultiple Airlines
Deal found 9/13$281

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Mesa to Charleston that are best for you.

Fly from

Mesa

Fly to

Charleston

Route

Depart

Return

Price

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Wed 10/29

8:00 pm-5:47 pm

2 stops18h 47m

Charleston

Sun 11/2

10:11 am-10:53 am

1 stop26h 42m

$267

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Fri 10/31

9:24 am-10:07 am

1 stop21h 43m

Charleston

Sun 11/2

9:05 pm-11:25 am

2 stops16h 20m

$271

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Fri 10/24

11:59 pm-10:49 am

1 stop7h 50m

Charleston

Mon 11/3

9:22 am-4:45 pm

1 stop9h 23m

$280

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Thu 10/23

10:59 pm-9:31 am

1 stop7h 32m

Charleston

Mon 11/3

9:22 am-4:45 pm

1 stop9h 23m

$280

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Fri 10/24

11:24 pm-8:37 am

1 stop30h 13m

Charleston

Mon 11/3

9:56 am-6:50 pm

2 stops34h 54m

$281

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Tue 10/14

10:56 am-8:37 am

2 stops42h 41m

Charleston

Tue 10/21

2:59 pm-1:17 pm

1 stop25h 18m

$289

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Wed 10/1

8:00 am-8:28 pm

1 stop9h 28m

Charleston

Sun 10/5

2:59 pm-9:56 pm

2 stops33h 57m

$295

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Thu 10/16

10:58 am-9:06 am

1 stop19h 08m

Charleston

Sun 10/19

9:38 pm-10:52 am

2 stops16h 14m

$305

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Wed 10/29

11:07 pm-1:19 pm

1 stop11h 12m

Charleston

Sun 11/2

5:20 pm-11:35 am

1 stop20h 15m

$316

PhoenixCharleston

PHX - CHS

PHXCHS

Phoenix Sky Harbor Intl

Tue 10/14

10:59 pm-10:20 am

1 stop8h 21m

Charleston

Tue 10/21

4:14 pm-8:46 pm

1 stop7h 32m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 19 results
1
2

Best time to book a flight from Mesa to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Charleston

How far ahead should I book a flight from Mesa to Charleston?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Charleston. Price data was last updated on September 12, 2025.

Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to Charleston?

Currently, August is the cheapest month in which you can book a flight from Mesa to Charleston (average of $217). Flying from Mesa to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to CHS?

Find hourly flight availability from Mesa to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Charleston as you normally would.

What is the cheapest day to fly from Mesa to Charleston?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Charleston. Price data was last updated on December 1, 2024.

Travelers seeking maximum savings on their Mesa to Charleston flight should consider departing on Saturday mornings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from Mesa to Charleston, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
8.0
Very good

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mesa to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Charleston from Mesa?

    Charleston (CHS), located 10.2 mi from the city center, is the airport you fly into when you book flights from Mesa to Charleston. 4 airlines have flights to Charleston from Mesa on a regular basis. Booking flights from Mesa to Charleston should not be difficult; the airport handles an average of 0 inbound flights from Mesa per day.

  • How long is the flight from Mesa to Charleston?

    For as low as $280, American Airlines can have you in Charleston from Mesa in 7h 50m. The distance between Mesa and Charleston is about 1840 mi.

  • Can I find deals for flights from Mesa to Charleston that include hotel bookings?

    Yes. In addition to deals on Mesa to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Charleston.

  • Can I find deals for business class flights from Mesa to Charleston?

    Yes. Cheapflights offers flight deals from Mesa to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Mesa to Charleston (average of $217). Flying from Mesa to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Santee
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Mesa to Charleston

Discover the top 4 airlines that operate flights from Mesa to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$329FlexibilityNo cancel feeOn-time71%
DeltaCheapest$256Average$396FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$339FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$258Average$422FlexibilityNo cancel feeOn-time63%

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