$105+ Cheap flights from Mesa, AZ to Charleston (CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — CHS
Mar 13 — Mar 201
1 adult, Economy
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Find cheap flights from Mesa to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Charleston are usually found in April or October, booked 87 days in advance, depart on a Tuesday or Monday and return on a Monday
Cheap flight deals from Mesa to Charleston
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to CharlestonExplore the most affordable flight options available from Mesa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
Explore the most affordable flight options available from Mesa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:45 pm
PHX
- CHS
2 stops11h 53m
Multiple Airlines
Sat 5/93:44 pm
CHS
- PHX
1 stop10h 34m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$234
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:15 am
PHX
- CHS
1 stop8h 01m
American Airlines
Sat 8/222:45 pm
CHS
- PHX
1 stop7h 22m
American Airlines
Deal found 2/11![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:45 pm
PHX
- CHS
2 stops13h 45m
Multiple Airlines
Sat 5/163:44 pm
CHS
- PHX
1 stop10h 34m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$244
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:00 am
PHX
- CHS
1 stop7h 13m
United Airlines
Tue 3/1010:20 am
CHS
- PHX
2 stops9h 59m
United Airlines
Deal found 2/9![United Airlines logo]()
$248
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:00 am
PHX
- CHS
1 stop7h 02m
American Airlines
Tue 3/313:54 pm
CHS
- PHX
1 stop6h 49m
American Airlines
Deal found 2/10![American Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:02 pm
PHX
- CHS
1 stop8h 24m
American Airlines
Wed 3/257:19 pm
CHS
- PHX
1 stop7h 25m
American Airlines
Deal found 2/10![American Airlines logo]()
$252
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:35 pm
PHX
- CHS
1 stop8h 34m
Delta
Mon 5/45:57 pm
CHS
- PHX
1 stop7h 42m
Delta
Deal found 2/9![Delta logo]()
$253
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:55 pm
PHX
- CHS
1 stop5h 48m
Delta
Sun 5/105:15 am
CHS
- PHX
1 stop7h 03m
Delta
Deal found 2/9![Delta logo]()
$271
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:55 am
PHX
- CHS
1 stop8h 35m
Southwest
Tue 3/177:55 am
CHS
- PHX
2 stops15h 35m
Southwest
Deal found 2/8![Southwest logo]()
$282
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:45 pm
PHX
- CHS
1 stop8h 22m
American Airlines
Wed 5/278:03 pm
CHS
- PHX
1 stop7h 11m
American Airlines
Deal found 2/11![American Airlines logo]()
$286
Best flights from Mesa to CharlestonDiscover carefully curated flight deals from Mesa to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
Discover carefully curated flight deals from Mesa to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:15 pm
PHX
- CHS
1 stop7h 42m
Delta
Sat 7/185:55 pm
CHS
- PHX
1 stop8h 07m
Delta
Deal found 2/7![Delta logo]()
$243
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:47 pm
PHX
- CHS
1 stop7h 26m
United Airlines
Tue 5/1210:15 am
CHS
- PHX
1 stop8h 00m
United Airlines
Deal found 2/9![United Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:55 pm
PHX
- CHS
1 stop9h 31m
American Airlines
Tue 3/313:48 pm
CHS
- PHX
1 stop8h 58m
American Airlines
Deal found 2/8![American Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:46 pm
PHX
- CHS
1 stop6h 54m
Delta
Tue 6/97:10 am
CHS
- PHX
1 stop9h 47m
Delta
Deal found 2/8![Delta logo]()
$243
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:40 pm
PHX
- CHS
1 stop7h 24m
United Airlines
Wed 3/255:06 pm
CHS
- PHX
1 stop7h 38m
United Airlines
Deal found 2/10![United Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:00 pm
PHX
- CHS
1 stop6h 09m
Delta
Sat 5/164:55 pm
CHS
- PHX
1 stop6h 27m
Delta
Deal found 2/8![Delta logo]()
$243
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:40 pm
PHX
- CHS
1 stop7h 24m
United Airlines
Tue 3/1710:20 am
CHS
- PHX
1 stop7h 53m
United Airlines
Deal found 2/8![United Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1111:46 pm
PHX
- CHS
1 stop6h 54m
Delta
Sat 5/166:05 pm
CHS
- PHX
1 stop7h 31m
Delta
Deal found 2/8![Delta logo]()
$243
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:35 pm
PHX
- CHS
1 stop7h 16m
Delta
Sat 4/258:25 am
CHS
- PHX
1 stop8h 27m
Delta
Deal found 2/11![Delta logo]()
$252
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:55 pm
PHX
- CHS
1 stop8h 29m
Delta
Mon 6/225:55 pm
CHS
- PHX
1 stop8h 07m
Delta
Deal found 2/10![Delta logo]()
$253
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:00 am
PHX
- CHS
1 stop8h 45m
Delta
Mon 6/225:55 pm
CHS
- PHX
1 stop8h 07m
Delta
Deal found 2/10![Delta logo]()
$253
Last-minute flights from Mesa to CharlestonDiscover last-minute flight deals from Mesa to Charleston. Data last updated February 11, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Charleston. Data last updated February 11, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:08 pm
PHX
- CHS
1 stop7h 22m
JetBlue
Wed 2/252:50 pm
CHS
- PHX
1 stop9h 59m
JetBlue
Deal found 2/7![JetBlue logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:30 am
PHX
- CHS
2 stops32h 10m
Multiple Airlines
Tue 3/33:01 pm
CHS
- PHX
1 stop9h 11m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:00 am
PHX
- CHS
1 stop7h 13m
United Airlines
Tue 3/1010:20 am
CHS
- PHX
2 stops9h 59m
United Airlines
Deal found 2/9![United Airlines logo]()
$248
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:40 pm
PHX
- CHS
1 stop8h 35m
Southwest
Mon 3/98:55 pm
CHS
- PHX
1 stop6h 35m
Southwest
Deal found 2/9![Southwest logo]()
$281
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:25 am
PHX
- CHS
1 stop7h 50m
Southwest
Mon 3/168:55 pm
CHS
- PHX
1 stop6h 35m
Southwest
Deal found 2/9![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:55 am
PHX
- CHS
1 stop8h 35m
Southwest
Tue 3/177:55 am
CHS
- PHX
2 stops15h 35m
Southwest
Deal found 2/8![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1311:55 pm
PHX
- CHS
1 stop6h 49m
Delta
Tue 3/175:27 am
CHS
- PHX
1 stop6h 53m
Delta
Deal found 2/9![Delta logo]()
$253
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:49 pm
PHX
- CHS
1 stop8h 51m
JetBlue
Thu 3/2612:05 pm
CHS
- PHX
1 stop13h 28m
JetBlue
Deal found 2/10![JetBlue logo]()
$291
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:02 pm
PHX
- CHS
1 stop8h 24m
American Airlines
Wed 3/257:19 pm
CHS
- PHX
1 stop7h 25m
American Airlines
Deal found 2/10![American Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:55 pm
PHX
- CHS
1 stop9h 20m
Southwest
Wed 3/2512:50 pm
CHS
- PHX
2 stops8h 50m
Southwest
Deal found 2/9![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:00 am
PHX
- CHS
1 stop7h 02m
American Airlines
Thu 3/268:19 pm
CHS
- PHX
1 stop6h 48m
American Airlines
Deal found 2/11![American Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:00 am
PHX
- CHS
1 stop7h 02m
American Airlines
Tue 3/313:54 pm
CHS
- PHX
1 stop6h 49m
American Airlines
Deal found 2/10![American Airlines logo]()
$251
One-way flights from Mesa to CharlestonSearch for one-way flight options from Mesa to Charleston. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
Search for one-way flight options from Mesa to Charleston. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:22 am
PHX
- CHS
2 stops26h 09m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$105
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:35 pm
PHX
- CHS
1 stop8h 34m
Delta
Deal found 2/8![Delta logo]()
$122
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:00 am
PHX
- CHS
1 stop6h 10m
American Airlines
Deal found 2/10![American Airlines logo]()
$126
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
PHX
- CHS
2 stops9h 45m
United Airlines
Deal found 2/10![United Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:22 am
PHX
- CHS
2 stops44h 18m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
PHX
- CHS
2 stops32h 05m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:39 pm
PHX
- CHS
3 stops33h 01m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/111:59 pm
PHX
- CHS
2 stops38h 06m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:54 pm
PHX
- CHS
3 stops29h 55m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$138
Find flight deals from Mesa to Charleston
Keep the following information in mind while searching for Mesa to Charleston flight deals. Data was last updated February 11, 2026.
Round-trip from | $234 (Kiwi.com) |
|---|---|
One-way from | $105 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $321 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Mesa to Charleston that are best for you.
Fly from
Mesa
Fly to
Charleston
Route
Depart
Return
Price
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 7/14
1:15 pm-11:57 pm
1 stop7h 42m
Charleston
Sat 7/18
5:55 pm-11:02 pm
1 stop8h 07m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Fri 5/8
11:47 pm-10:13 am
1 stop7h 26m
Charleston
Tue 5/12
10:15 am-3:15 pm
1 stop8h 00m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 3/24
9:55 pm-10:26 am
1 stop9h 31m
Charleston
Tue 3/31
3:48 pm-9:46 pm
1 stop8h 58m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Wed 5/27
11:46 pm-9:40 am
1 stop6h 54m
Charleston
Tue 6/9
7:10 am-1:57 pm
1 stop9h 47m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Mon 3/23
11:40 pm-10:04 am
1 stop7h 24m
Charleston
Wed 3/25
5:06 pm-9:44 pm
1 stop7h 38m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 5/12
3:00 pm-12:09 am
1 stop6h 09m
Charleston
Sat 5/16
4:55 pm-8:22 pm
1 stop6h 27m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 3/10
11:40 pm-10:04 am
1 stop7h 24m
Charleston
Tue 3/17
10:20 am-3:13 pm
1 stop7h 53m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Mon 5/11
11:46 pm-9:40 am
1 stop6h 54m
Charleston
Sat 5/16
6:05 pm-10:36 pm
1 stop7h 31m
$243
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Thu 4/23
10:35 pm-8:51 am
1 stop7h 16m
Charleston
Sat 4/25
8:25 am-1:52 pm
1 stop8h 27m
$252
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Mon 6/15
11:55 pm-11:24 am
1 stop8h 29m
Charleston
Mon 6/22
5:55 pm-11:02 pm
1 stop8h 07m
$253
Showing 1-10 of 23 results
Best time to book a flight from Mesa to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Mesa with our price prediction graph.
PHX-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Charleston
MS9-CHS
PHX-CHS
How far ahead should I book a flight from Mesa to Charleston?
Use this chart to determine the optimal time to book a round-trip flight from Mesa to Charleston. Price data was last updated on February 6, 2026.
Booking 86 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Charleston. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Mesa to Charleston?
Currently, October is the cheapest month in which you can book a flight from Mesa to Charleston (average of $192). Flying from Mesa to Charleston in November is currently the most expensive (average of $273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated February 11, 2026.
Read through reviews of airlines operating flights from Mesa to Charleston, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Mesa to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Mesa to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to Charleston by cabin class
Find flights from Mesa to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mesa and Charleston flights
Browse other Mesa and Charleston flight options. Last updated on February 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mesa to Charleston flights
Consider these flights traveling from Mesa to Charleston.
Top 4 airlines flying from Mesa to Charleston
Discover the top 4 airlines that operate flights from Mesa to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$321 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$242 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$416 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$258 | Average$292 | FlexibilityNo cancel fee | On-time69% |