$143+ Cheap flights from South Carolina to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Sep 7 — Sep 141
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Cayman Islands with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to Cayman IslandsExplore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 8, 2026.
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 8, 2026.
This Expedia deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:55 am -
1 stop27h 15m
Tue 11/101:10 pm -
1 stop27h 16m
Deal found 8/3![Air Canada logo]()
$399
This Air Canada deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:10 pm -
1 stop19h 00m
Sat 11/141:10 pm -
1 stop7h 56m
Deal found 8/7![Air Canada logo]()
$407
This Air Canada deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:10 pm -
1 stop19h 00m
Fri 12/111:10 pm -
1 stop7h 56m
Deal found 8/7![Air Canada logo]()
$446
This Air Canada deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 pm -
1 stop19h 00m
Tue 11/31:10 pm -
1 stop7h 56m
Deal found 8/7![Air Canada logo]()
$472
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:24 pm -
1 stop21h 56m
Fri 9/1811:25 am -
1 stop4h 58m
Deal found 8/5![Multiple Airlines logo]()
$491
This Justfly.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:10 pm -
1 stop19h 00m
Sun 11/291:10 pm -
1 stop27h 16m
Deal found 8/4![Air Canada logo]()
$500
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:24 pm -
1 stop21h 56m
Sun 9/2012:40 pm -
2 stops24h 48m
Deal found 8/5![Multiple Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:59 pm -
2 stops17h 51m
Sun 9/137:00 am -
1 stop5h 55m
Deal found 8/3![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:27 pm -
1 stop17h 08m
Tue 9/2211:30 am -
1 stop8h 44m
Deal found 8/5![Multiple Airlines logo]()
$518
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:59 pm -
1 stop19h 06m
Sat 9/268:50 am -
1 stop8h 32m
Deal found 8/5![Multiple Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:59 pm -
1 stop19h 06m
Tue 9/2211:30 am -
1 stop8h 44m
Deal found 8/5![Multiple Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:32 pm -
1 stop14h 51m
Fri 11/612:55 pm -
1 stop6h 39m
Deal found 8/4![American Airlines logo]()
$529
Best flights from South Carolina to Cayman IslandsDiscover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 8, 2026.
Discover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 8, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:32 pm -
1 stop14h 51m
Fri 11/612:55 pm -
1 stop6h 39m
Deal found 8/5![American Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:10 am -
1 stop7h 29m
Sat 9/51:04 pm -
1 stop5h 46m
Deal found 8/3![Delta logo]()
$529
This Justfly.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:55 am -
1 stop27h 15m
Sat 11/281:10 pm -
1 stop27h 16m
Deal found 8/6![Air Canada logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:11 pm -
2 stops28h 54m
Thu 10/1512:40 pm -
1 stop24h 45m
Deal found 8/8![Multiple Airlines logo]()
$574
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:30 am -
1 stop7h 15m
Wed 1/272:55 pm -
1 stop30h 21m
Deal found 8/5![United Airlines logo]()
$742
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:11 am -
1 stop6h 16m
Wed 9/912:00 pm -
1 stop8h 36m
Deal found 8/4![American Airlines logo]()
$529
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:10 am -
2 stops9h 00m
Sat 12/262:20 pm -
2 stops9h 55m
Deal found 8/3![Southwest logo]()
$1,092
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:27 am -
1 stop5h 23m
Thu 12/247:30 am -
2 stops10h 17m
Deal found 8/3![American Airlines logo]()
$534
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:40 am -
1 stop5h 00m
Fri 1/292:05 pm -
1 stop7h 41m
Deal found 8/7![Delta logo]()
$604
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:30 am -
Nonstop2h 57m
Thu 9/1012:36 pm -
Nonstop3h 09m
Deal found 8/6![American Airlines logo]()
$597
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:40 am -
1 stop5h 00m
Sat 9/191:05 pm -
1 stop6h 08m
Deal found 8/5![Delta logo]()
$671
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:30 am -
1 stop7h 15m
Wed 1/272:55 pm -
1 stop30h 21m
Deal found 8/3![United Airlines logo]()
$813
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:41 am -
1 stop11h 42m
Tue 2/912:55 pm -
Nonstop3h 00m
Deal found 8/3![American Airlines logo]()
$621
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 40m
Mon 10/1212:55 pm -
1 stop10h 04m
Deal found 8/4![Delta logo]()
$711
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2511:00 am -
1 stop26h 15m
Wed 1/272:25 pm -
1 stop9h 00m
Deal found 8/3![United Airlines logo]()
$814
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:03 am -
2 stops9h 07m
Sat 10/1711:55 am -
2 stops11h 01m
Deal found 8/6![American Airlines logo]()
$632
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop6h 40m
Sun 9/131:00 pm -
1 stop6h 13m
Deal found 8/4![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:00 am -
1 stop9h 25m
Tue 12/2212:55 pm -
1 stop11h 03m
Deal found 8/3![American Airlines logo]()
$650
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:55 am -
1 stop5h 45m
Thu 9/171:00 pm -
1 stop9h 59m
Deal found 8/5![Delta logo]()
$717
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:30 am -
1 stop14h 28m
Fri 12/49:00 am -
2 stops11h 48m
Deal found 8/8![American Airlines logo]()
$655
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:30 am -
Nonstop3h 00m
Tue 10/2012:35 pm -
Nonstop3h 05m
Deal found 8/6![American Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop6h 56m
Fri 12/1112:55 pm -
1 stop11h 01m
Deal found 8/6![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am -
1 stop6h 27m
Thu 9/1012:36 pm -
1 stop6h 49m
Deal found 8/7![American Airlines logo]()
$665
This Air Canada deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:00 pm -
2 stops17h 10m
Wed 1/271:10 pm -
2 stops34h 15m
Deal found 8/4![Air Canada logo]()
$1,612
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:49 pm -
2 stops19h 06m
Thu 10/1512:00 pm -
2 stops6h 51m
Deal found 8/5![American Airlines logo]()
$676
This FlightHub deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:35 am -
2 stops24h 35m
Sun 11/291:10 pm -
2 stops32h 14m
Deal found 8/3![Air Canada logo]()
$1,663
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:55 pm -
1 stop14h 15m
Sun 9/2012:36 pm -
Nonstop3h 09m
Deal found 8/3![American Airlines logo]()
$706
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:47 pm -
2 stops17h 40m
Fri 9/2512:36 pm -
1 stop7h 24m
Deal found 8/4![American Airlines logo]()
$709
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/199:36 am -
1 stop10h 42m
Sat 12/263:45 pm -
1 stop8h 54m
Deal found 8/3![American Airlines logo]()
$796
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:53 am -
1 stop5h 12m
Sun 11/293:45 pm -
1 stop5h 37m
Deal found 8/6![American Airlines logo]()
$1,043
Last-minute flights from South Carolina to Cayman IslandsDiscover last-minute flight deals from South Carolina to Cayman Islands. Data last updated August 8, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Cayman Islands. Data last updated August 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:11 am -
1 stop6h 16m
Wed 9/912:00 pm -
1 stop8h 36m
Deal found 8/4![American Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:24 pm -
1 stop21h 56m
Fri 9/1811:25 am -
1 stop4h 58m
Deal found 8/5![Multiple Airlines logo]()
$491
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:24 pm -
1 stop21h 56m
Sun 9/2012:40 pm -
2 stops24h 48m
Deal found 8/5![Multiple Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:00 pm -
1 stop21h 35m
Fri 9/184:45 pm -
1 stop24h 37m
Deal found 8/5![Multiple Airlines logo]()
$532
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:59 pm -
2 stops17h 51m
Sun 9/137:00 am -
1 stop5h 55m
Deal found 8/3![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:59 pm -
1 stop19h 06m
Tue 9/2211:30 am -
1 stop8h 44m
Deal found 8/5![Multiple Airlines logo]()
$522
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:59 pm -
1 stop14h 36m
Sun 9/207:00 am -
1 stop5h 55m
Deal found 8/3![Multiple Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:27 pm -
1 stop17h 08m
Tue 9/2211:30 am -
1 stop8h 44m
Deal found 8/5![Multiple Airlines logo]()
$518
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:27 pm -
1 stop17h 08m
Sat 9/268:50 am -
1 stop8h 32m
Deal found 8/4![Multiple Airlines logo]()
$530
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:59 pm -
1 stop14h 36m
Tue 9/2211:30 am -
1 stop8h 44m
Deal found 8/5![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:59 pm -
1 stop19h 06m
Sat 9/268:50 am -
1 stop8h 32m
Deal found 8/5![Multiple Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:27 am -
1 stop10h 48m
Sun 9/277:00 am -
1 stop5h 55m
Deal found 8/8![Multiple Airlines logo]()
$519
One-way flights from South Carolina to Cayman IslandsSearch for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated August 8, 2026.
Search for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated August 8, 2026.
This Air Canada deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:40 pm -
1 stop20h 45m
Deal found 8/4![Air Canada logo]()
$143
This Travelocity deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:55 am -
1 stop27h 15m
Deal found 8/6![Air Canada logo]()
$154
This Expedia deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:10 pm -
1 stop19h 00m
Deal found 8/5![Air Canada logo]()
$171
This Air Canada deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:55 am -
1 stop27h 15m
Deal found 8/4![Air Canada logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:59 pm -
1 stop19h 06m
Deal found 8/8![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:00 pm -
1 stop21h 35m
Deal found 8/7![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:59 pm -
2 stops17h 51m
Deal found 8/8![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:00 pm -
1 stop21h 35m
Deal found 8/5![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:59 pm -
1 stop8h 16m
Deal found 8/8![Multiple Airlines logo]()
$204
This Trip.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:58 pm -
1 stop8h 17m
Deal found 8/8![Multiple Airlines logo]()
$208
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
2 stops8h 24m
Deal found 8/3![American Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:23 am -
1 stop6h 12m
Deal found 8/6![United Airlines logo]()
$272
Find flight deals from South Carolina to Cayman Islands
Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated August 8, 2026.
Round-trip from | $399 (Expedia) |
|---|---|
One-way from | $143 (Air Canada) |
Popular in | February |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 8, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGeorge Town
CHS Charleston - GCM George Town Owen Roberts Intl
CHSGCM
Charleston
Sun 11/1
8:32 pm-11:23 am
1 stop14h 51m
George Town Owen Roberts Intl
Fri 11/6
12:55 pm-7:34 pm
1 stop6h 39m
$529
CharlestonGeorge Town
CHS Charleston - GCM George Town Owen Roberts Intl
CHSGCM
Charleston
Fri 8/28
5:10 am-11:39 am
1 stop7h 29m
George Town Owen Roberts Intl
Sat 9/5
1:04 pm-7:50 pm
1 stop5h 46m
$529
CharlestonGeorge Town
CHS Charleston - GCM George Town Owen Roberts Intl
CHSGCM
Charleston
Thu 9/3
6:11 am-11:27 am
1 stop6h 16m
George Town Owen Roberts Intl
Wed 9/9
12:00 pm-9:36 pm
1 stop8h 36m
$529
CharlestonGeorge Town
CHS Charleston - GCM George Town Owen Roberts Intl
CHSGCM
Charleston
Thu 12/17
9:27 am-2:50 pm
1 stop5h 23m
George Town Owen Roberts Intl
Thu 12/24
7:30 am-5:47 pm
2 stops10h 17m
$534
CharlotteGeorge Town
CLT Charlotte Douglas - GCM George Town Owen Roberts Intl
CLTGCM
Charlotte Douglas
Tue 11/24
8:55 am-12:10 pm
1 stop27h 15m
George Town Owen Roberts Intl
Sat 11/28
1:10 pm-4:26 pm
1 stop27h 16m
$570
GreenvilleGeorge Town
GSP Greenville - GCM George Town Owen Roberts Intl
GSPGCM
Greenville
Fri 10/2
12:11 pm-4:05 pm
2 stops28h 54m
George Town Owen Roberts Intl
Thu 10/15
12:40 pm-2:25 pm
1 stop24h 45m
$574
CharlotteGeorge Town
CLT Charlotte Douglas - GCM George Town Owen Roberts Intl
CLTGCM
Charlotte Douglas
Mon 9/7
9:30 am-11:27 am
Nonstop2h 57m
George Town Owen Roberts Intl
Thu 9/10
12:36 pm-4:45 pm
Nonstop3h 09m
$597
CharlestonGeorge Town
CHS Charleston - GCM George Town Owen Roberts Intl
CHSGCM
Charleston
Mon 1/25
7:40 am-12:40 pm
1 stop5h 00m
George Town Owen Roberts Intl
Fri 1/29
2:05 pm-9:46 pm
1 stop7h 41m
$604
CharlotteGeorge Town
CLT Charlotte Douglas - GCM George Town Owen Roberts Intl
CLTGCM
Charlotte Douglas
Tue 1/12
8:41 am-8:23 pm
1 stop11h 42m
George Town Owen Roberts Intl
Tue 2/9
12:55 pm-3:55 pm
Nonstop3h 00m
$621
CharlestonGeorge Town
CHS Charleston - GCM George Town Owen Roberts Intl
CHSGCM
Charleston
Mon 10/12
5:03 am-1:10 pm
2 stops9h 07m
George Town Owen Roberts Intl
Sat 10/17
11:55 am-11:56 pm
2 stops11h 01m
$632
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
CHS-GCM
CLT-GCM
GSP-GCM
CAE-GCM
SAV-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to the Cayman Islands
USSC-KY0
CHS-GCM
CLT-GCM
GSP-GCM
CAE-GCM
What is the cheapest month to book a flight from South Carolina to Cayman Islands?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $309). Flying from South Carolina to Cayman Islands in September is currently the most expensive (average of $999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Cayman Islands by cabin class
Find flights from South Carolina to Cayman Islands, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Cayman Islands flights
Browse other South Carolina and Cayman Islands flight options. Last updated on August 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top 2 airlines flying from South Carolina to Cayman Islands
Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$692 | FlexibilityNo cancel fee | On-time71% |