$170+ Cheap flights from South Carolina to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Aug 13 — Aug 201
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Cayman Islands with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to Cayman IslandsExplore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
This Air Canada deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:40 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Sun 10/2512:10 pm
GCM
- CLT
1 stop7h 56m
Air Canada
Deal found 7/11![Air Canada logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Mon 8/317:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$465
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
CHS
- GCM
1 stop11h 10m
American Airlines
Thu 7/235:10 pm
GCM
- CHS
1 stop5h 49m
American Airlines
Deal found 7/13![American Airlines logo]()
$469
This Air Canada deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Tue 11/31:10 pm
GCM
- CLT
1 stop7h 56m
Air Canada
Deal found 7/11![Air Canada logo]()
$472
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:42 pm
CHS
- GCM
1 stop16h 48m
American Airlines
Fri 8/1412:30 pm
GCM
- CHS
1 stop9h 30m
American Airlines
Deal found 7/10![American Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:06 pm
CHS
- GCM
2 stops19h 54m
American Airlines
Sun 8/232:10 pm
GCM
- CHS
2 stops18h 29m
American Airlines
Deal found 7/10![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:41 am
CHS
- GCM
1 stop5h 44m
American Airlines
Sun 7/262:41 pm
GCM
- CHS
1 stop20h 47m
American Airlines
Deal found 7/11![American Airlines logo]()
$484
This Air Canada deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:40 pm
CLT
- GCM
1 stop20h 45m
Air Canada
Thu 9/1712:25 pm
GCM
- CLT
1 stop7h 32m
Air Canada
Deal found 7/8![Air Canada logo]()
$491
This Air Canada deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:10 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Sat 11/141:10 pm
GCM
- CLT
1 stop7h 56m
Air Canada
Deal found 7/11![Air Canada logo]()
$499
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
CHS
- GCM
1 stop6h 00m
American Airlines
Fri 7/315:10 pm
GCM
- CHS
1 stop5h 49m
American Airlines
Deal found 7/13![American Airlines logo]()
$505
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:19 pm
CLT
- GCM
1 stop7h 56m
Multiple Airlines
Sun 10/47:00 am
GCM
- CLT
1 stop8h 05m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$508
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:00 am
CHS
- GCM
2 stops9h 20m
American Airlines
Fri 11/139:00 am
GCM
- CHS
2 stops12h 05m
American Airlines
Deal found 7/10![American Airlines logo]()
$510
Best flights from South Carolina to Cayman IslandsDiscover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
Discover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:00 am
CHS
- GCM
1 stop7h 25m
American Airlines
Fri 7/315:10 pm
GCM
- CHS
2 stops16h 06m
American Airlines
Deal found 7/13![American Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Tue 7/2811:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$602
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:46 am
GSP
- GCM
1 stop6h 53m
Delta
Tue 8/251:04 pm
GCM
- GSP
1 stop8h 55m
Delta
Deal found 7/12![Delta logo]()
$631
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:17 pm
CHS
- GCM
2 stops16h 43m
American Airlines
Fri 8/1412:30 pm
GCM
- CHS
2 stops10h 29m
American Airlines
Deal found 7/10![American Airlines logo]()
$474
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 am
CHS
- GCM
1 stop5h 58m
American Airlines
Fri 11/139:00 am
GCM
- CHS
2 stops12h 05m
American Airlines
Deal found 7/10![American Airlines logo]()
$474
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:10 am
CHS
- GCM
2 stops6h 48m
American Airlines
Sun 11/81:00 pm
GCM
- CHS
1 stop11h 23m
American Airlines
Deal found 7/13![American Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:55 am
GSP
- GCM
1 stop5h 44m
Delta
Wed 8/261:04 pm
GCM
- GSP
1 stop6h 28m
Delta
Deal found 7/12![Delta logo]()
$631
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:10 am
CHS
- GCM
1 stop6h 50m
American Airlines
Sun 12/207:30 am
GCM
- CHS
2 stops14h 41m
American Airlines
Deal found 7/13![American Airlines logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Tue 8/1811:30 am
GCM
- CLT
2 stops20h 21m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$648
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:30 am
CLT
- GCM
1 stop7h 09m
Delta
Sun 8/301:04 pm
GCM
- CLT
1 stop6h 21m
Delta
Deal found 7/12![Delta logo]()
$651
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:40 am
CLT
- GCM
1 stop5h 00m
Delta
Sun 9/131:00 pm
GCM
- CLT
1 stop6h 13m
Delta
Deal found 7/13![Delta logo]()
$651
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:32 pm
CHS
- GCM
1 stop18h 08m
American Airlines
Fri 11/61:00 pm
GCM
- CHS
1 stop11h 23m
American Airlines
Deal found 7/13![American Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:55 am
GSP
- GCM
1 stop5h 44m
Delta
Tue 8/251:04 pm
GCM
- GSP
1 stop6h 28m
Delta
Deal found 7/12![Delta logo]()
$656
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
CLT
- GCM
1 stop6h 40m
Delta
Mon 10/1212:55 pm
GCM
- CLT
1 stop9h 59m
Delta
Deal found 7/13![Delta logo]()
$691
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:11 pm
CAE
- GCM
1 stop15h 49m
American Airlines
Sun 12/203:11 pm
GCM
- CAE
1 stop8h 56m
American Airlines
Deal found 7/13![American Airlines logo]()
$646
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
CLT
- GCM
1 stop6h 40m
Delta
Sat 10/1012:55 pm
GCM
- CLT
1 stop6h 19m
Delta
Deal found 7/11![Delta logo]()
$691
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/189:36 am
SAV
- GCM
1 stop10h 42m
American Airlines
Sat 12/267:30 am
GCM
- SAV
1 stop8h 22m
American Airlines
Deal found 7/10![American Airlines logo]()
$671
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:55 am
CLT
- GCM
1 stop5h 45m
Delta
Mon 10/1212:55 pm
GCM
- CLT
1 stop9h 59m
Delta
Deal found 7/13![Delta logo]()
$691
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
GSP
- GCM
1 stop5h 00m
American Airlines
Sun 8/2312:30 pm
GCM
- GSP
1 stop8h 42m
American Airlines
Deal found 7/13![American Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:55 am
GSP
- GCM
1 stop5h 44m
Delta
Tue 8/251:04 pm
GCM
- GSP
1 stop6h 28m
Delta
Deal found 7/12![Delta logo]()
$723
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:20 am
CLT
- GCM
1 stop6h 40m
American Airlines
Thu 9/1012:36 pm
GCM
- CLT
Nonstop3h 09m
American Airlines
Deal found 7/9![American Airlines logo]()
$687
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:35 am
SAV
- GCM
1 stop6h 04m
Delta
Mon 8/101:04 pm
GCM
- SAV
1 stop10h 17m
Delta
Deal found 7/11![Delta logo]()
$741
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
SAV
- GCM
1 stop8h 10m
American Airlines
Mon 8/102:10 pm
GCM
- SAV
1 stop8h 49m
American Airlines
Deal found 7/11![American Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:35 am
SAV
- GCM
1 stop6h 04m
Delta
Mon 8/101:04 pm
GCM
- SAV
1 stop8h 31m
Delta
Deal found 7/11![Delta logo]()
$741
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:26 pm
SAV
- GCM
2 stops18h 44m
American Airlines
Mon 8/1012:30 pm
GCM
- SAV
2 stops10h 29m
American Airlines
Deal found 7/11![American Airlines logo]()
$721
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:46 am
GSP
- GCM
1 stop6h 53m
Delta
Sun 8/301:04 pm
GCM
- GSP
1 stop8h 55m
Delta
Deal found 7/12![Delta logo]()
$748
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:24 am
GSP
- GCM
1 stop9h 56m
American Airlines
Fri 12/49:00 am
GCM
- GSP
2 stops11h 48m
American Airlines
Deal found 7/10![American Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:25 pm
CAE
- GCM
3 stops23h 05m
United Airlines
Sun 12/205:15 pm
GCM
- CAE
2 stops17h 27m
United Airlines
Deal found 7/13![United Airlines logo]()
$4,691
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:28 pm
SAV
- GCM
2 stops20h 27m
American Airlines
Tue 8/1112:00 pm
GCM
- SAV
1 stop10h 37m
American Airlines
Deal found 7/11![American Airlines logo]()
$836
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:35 am
SAV
- GCM
1 stop6h 04m
Delta
Tue 8/111:04 pm
GCM
- SAV
1 stop7h 34m
Delta
Deal found 7/11![Delta logo]()
$1,011
Last-minute flights from South Carolina to Cayman IslandsDiscover last-minute flight deals from South Carolina to Cayman Islands. Data last updated July 14, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Cayman Islands. Data last updated July 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:41 am
CHS
- GCM
1 stop5h 44m
American Airlines
Sun 7/262:41 pm
GCM
- CHS
1 stop20h 47m
American Airlines
Deal found 7/11![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
CHS
- GCM
1 stop11h 10m
American Airlines
Thu 7/235:10 pm
GCM
- CHS
1 stop5h 49m
American Airlines
Deal found 7/13![American Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
CHS
- GCM
1 stop6h 00m
American Airlines
Fri 7/315:10 pm
GCM
- CHS
1 stop5h 49m
American Airlines
Deal found 7/13![American Airlines logo]()
$505
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Mon 8/34:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Tue 8/411:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Wed 8/511:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$530
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Mon 8/34:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Wed 8/511:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:42 pm
CHS
- GCM
1 stop16h 48m
American Airlines
Fri 8/1412:30 pm
GCM
- CHS
1 stop9h 30m
American Airlines
Deal found 7/10![American Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:06 pm
CHS
- GCM
2 stops19h 54m
American Airlines
Sun 8/232:10 pm
GCM
- CHS
2 stops18h 29m
American Airlines
Deal found 7/10![American Airlines logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:21 pm
CLT
- GCM
2 stops28h 54m
Multiple Airlines
Mon 8/317:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Mon 8/317:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$465
One-way flights from South Carolina to Cayman IslandsSearch for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
Search for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
This FlightHub deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:15 am
CLT
- GCM
1 stop25h 30m
Air Canada
Deal found 7/11![Air Canada logo]()
$170
This Air Canada deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:15 am
CLT
- GCM
1 stop27h 10m
Air Canada
Deal found 7/13![Air Canada logo]()
$175
This Trip.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/71:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$177
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:30 am
CHS
- GCM
1 stop5h 55m
Delta
Deal found 7/12![Delta logo]()
$182
This Air Canada deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:40 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Deal found 7/11![Air Canada logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$191
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:07 am
CHS
- GCM
2 stops9h 08m
American Airlines
Deal found 7/13![American Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:48 pm
CLT
- GCM
1 stop27h 27m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
CLT
- GCM
1 stop22h 37m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$194
This Air Canada deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:40 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Deal found 7/11![Air Canada logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:59 pm
CLT
- GCM
1 stop22h 36m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$208
Find flight deals from South Carolina to Cayman Islands
Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated July 14, 2026.
Round-trip from | $442 (Air Canada) |
|---|---|
One-way from | $170 (FlightHub) |
Popular in | February |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 7/27
5:00 am-11:25 am
1 stop7h 25m
George Town Owen Roberts Intl
Fri 7/31
5:10 pm-10:16 am
2 stops16h 06m
$474
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Sat 8/8
7:17 pm-11:00 am
2 stops16h 43m
George Town Owen Roberts Intl
Fri 8/14
12:30 pm-11:59 pm
2 stops10h 29m
$474
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Fri 11/6
6:00 am-11:58 am
1 stop5h 58m
George Town Owen Roberts Intl
Fri 11/13
9:00 am-9:05 pm
2 stops12h 05m
$474
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 11/3
5:10 am-11:58 am
2 stops6h 48m
George Town Owen Roberts Intl
Sun 11/8
1:00 pm-12:23 am
1 stop11h 23m
$479
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 12/14
5:10 am-12:00 pm
1 stop6h 50m
George Town Owen Roberts Intl
Sun 12/20
7:30 am-10:11 pm
2 stops14h 41m
$479
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Sun 11/1
6:32 pm-12:40 pm
1 stop18h 08m
George Town Owen Roberts Intl
Fri 11/6
1:00 pm-12:23 am
1 stop11h 23m
$562
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Thu 7/23
6:48 pm-11:35 am
1 stop17h 47m
George Town Owen Roberts Intl
Tue 7/28
11:30 am-5:12 pm
1 stop28h 42m
$602
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Sun 8/9
5:46 am-11:39 am
1 stop6h 53m
George Town Owen Roberts Intl
Tue 8/25
1:04 pm-10:59 pm
1 stop8h 55m
$631
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Sun 8/9
6:55 am-11:39 am
1 stop5h 44m
George Town Owen Roberts Intl
Wed 8/26
1:04 pm-8:32 pm
1 stop6h 28m
$631
ColumbiaGeorge Town
CAE - GCM
CAEGCM
Columbia Metropolitan
Mon 12/14
8:11 pm-12:00 pm
1 stop15h 49m
George Town Owen Roberts Intl
Sun 12/20
3:11 pm-12:07 am
1 stop8h 56m
$646
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
CHS-GCM
CLT-GCM
GSP-GCM
CAE-GCM
SAV-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to the Cayman Islands
USSC-KY0
CHS-GCM
CLT-GCM
GSP-GCM
CAE-GCM
What is the cheapest month to book a flight from South Carolina to Cayman Islands?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $286). Flying from South Carolina to Cayman Islands in December is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Cayman Islands by cabin class
Find flights from South Carolina to Cayman Islands, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Cayman Islands flights
Browse other South Carolina and Cayman Islands flight options. Last updated on July 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top 2 airlines flying from South Carolina to Cayman Islands
Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$697 | FlexibilityNo cancel fee | On-time71% |