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Cayman Islands

$91+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated January 8, 2026.

Round-trip from

$217
(Priceline)

One-way from

$91
(Delta)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Priceline deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:00 amCLT - GCM
1 stop7h 38mSpirit Airlines
Sat 2/72:34 pmGCM - CLT
1 stop10h 06mSpirit Airlines
Deal found 1/7$217
This FlightHub deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:00 amCLT - GCM
1 stop7h 53mSpirit Airlines
Sun 1/252:49 pmGCM - CLT
1 stop9h 51mSpirit Airlines
Deal found 1/8$237
This FlightHub deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:00 amCLT - GCM
1 stop7h 53mSpirit Airlines
Thu 2/52:49 pmGCM - CLT
1 stop9h 51mSpirit Airlines
Deal found 1/8$257
This Priceline deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 amCLT - GCM
1 stop7h 53mSpirit Airlines
Thu 2/122:49 pmGCM - CLT
1 stop9h 07mSpirit Airlines
Deal found 1/6$274
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/177:05 amCHS - GCM
1 stop8h 20mAmerican Airlines
Fri 2/208:45 amGCM - CHS
1 stop15h 14mAmerican Airlines
Deal found 1/7$287
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/196:00 amCHS - GCM
1 stop14h 20mAmerican Airlines
Wed 1/2112:16 pmGCM - CHS
1 stop8h 52mAmerican Airlines
Deal found 1/7$288
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/106:00 amCHS - GCM
1 stop8h 45mAmerican Airlines
Mon 1/1212:50 pmGCM - CHS
1 stop11h 08mAmerican Airlines
Deal found 1/6$289
This WAYA deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:00 amCLT - GCM
1 stop7h 53mMultiple Airlines
Sun 2/12:49 pmGCM - CLT
1 stop6h 58mMultiple Airlines
Deal found 1/6$289
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:02 pmCLT - GCM
1 stop19h 36mMultiple Airlines
Sun 2/12:49 pmGCM - CLT
1 stop6h 58mMultiple Airlines
Deal found 1/6$291
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:50 amCHS - GCM
2 stops13h 25mAmerican Airlines
Fri 2/208:45 amGCM - CHS
1 stop15h 14mAmerican Airlines
Deal found 1/7$292
This FlightHub deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:00 amCLT - GCM
1 stop7h 53mSpirit Airlines
Sun 2/12:49 pmGCM - CLT
1 stop9h 51mSpirit Airlines
Deal found 1/7$294
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:13 pmCHS - GCM
1 stop15h 37mAmerican Airlines
Sat 3/73:45 pmGCM - CHS
1 stop17h 41mAmerican Airlines
Deal found 1/8$295

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 1/29

6:00 am-1:53 pm

1 stop7h 53m

George Town Owen Roberts Intl

Thu 2/5

2:49 pm-12:40 am

1 stop9h 51m

$257

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/28

5:27 am-11:00 am

1 stop5h 33m

George Town Owen Roberts Intl

Sat 3/7

12:25 pm-7:56 pm

1 stop7h 31m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 2/17

7:05 am-3:25 pm

1 stop8h 20m

George Town Owen Roberts Intl

Fri 2/20

8:45 am-11:59 pm

1 stop15h 14m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 2/19

5:10 am-12:08 pm

1 stop6h 58m

George Town Owen Roberts Intl

Mon 2/23

12:50 pm-11:59 pm

1 stop11h 09m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 1/19

6:00 am-8:20 pm

1 stop14h 20m

George Town Owen Roberts Intl

Wed 1/21

12:16 pm-9:08 pm

1 stop8h 52m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/21

6:35 am-4:20 pm

1 stop9h 45m

George Town Owen Roberts Intl

Sat 2/28

5:30 pm-10:09 am

1 stop16h 39m

$289

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Wed 2/18

6:50 am-8:15 pm

2 stops13h 25m

George Town Owen Roberts Intl

Fri 2/20

8:45 am-11:59 pm

1 stop15h 14m

$292

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/28

8:13 pm-11:50 am

1 stop15h 37m

George Town Owen Roberts Intl

Sat 3/7

3:45 pm-9:26 am

1 stop17h 41m

$295

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 2/20

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Mon 2/23

2:50 pm-12:30 pm

1 stop21h 40m

$296

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Wed 3/4

6:00 am-8:15 pm

1 stop14h 15m

George Town Owen Roberts Intl

Sun 3/8

2:35 pm-10:26 am

1 stop18h 51m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Showing 1-10 of 54 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $332). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 5h 33m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $332). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Cayman Islands

Discover the top airline that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$608FlexibilityNo cancel feeOn-time71%

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