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Cayman Islands

$96+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Feb 18 — Feb 251
Wed 2/18
Wed 2/25
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated January 19, 2026.

Round-trip from

$287
(United Airlines)

One-way from

$96
(Priceline)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 19, 2026.

This United Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:00 am
CHS
-
GCM
1 stop7h 15m
United Airlines
Sat 2/145:30 pm
GCM
-
CHS
1 stop16h 39m
United Airlines
Deal found 1/17$287
This American Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:10 am
CHS
-
GCM
1 stop9h 04m
American Airlines
Mon 2/2312:50 pm
GCM
-
CHS
1 stop11h 09m
American Airlines
Deal found 1/17$288
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:35 am
CHS
-
GCM
1 stop5h 12m
Delta
Wed 4/1512:45 pm
GCM
-
CHS
1 stop8h 23m
Delta
Deal found 1/16$289
This American Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:10 am
CHS
-
GCM
2 stops14h 10m
American Airlines
Sat 2/143:45 pm
GCM
-
CHS
1 stop8h 14m
American Airlines
Deal found 1/17$292
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:21 pm
CHS
-
GCM
2 stops17h 50m
American Airlines
Fri 5/82:10 pm
GCM
-
CHS
2 stops17h 21m
American Airlines
Deal found 1/18$294
This Priceline deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
CLT
-
GCM
1 stop7h 20m
Spirit Airlines
Sat 3/211:15 pm
GCM
-
CLT
1 stop6h 08m
Spirit Airlines
Deal found 1/18$296
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:10 am
CHS
-
GCM
2 stops8h 35m
American Airlines
Sun 2/13:45 pm
GCM
-
CHS
2 stops18h 03m
American Airlines
Deal found 1/18$298
This Kiwi.com deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:07 am
CHS
-
GCM
1 stop5h 13m
Spirit Airlines
Thu 4/161:40 pm
GCM
-
CHS
1 stop8h 01m
Spirit Airlines
Deal found 1/16$334
This WAYA deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:00 am
CLT
-
GCM
1 stop7h 53m
Spirit Airlines
Thu 2/122:49 pm
GCM
-
CLT
1 stop9h 07m
Spirit Airlines
Deal found 1/17$336
This Kiwi.com deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:07 am
CHS
-
GCM
1 stop5h 13m
Spirit Airlines
Sat 4/181:40 pm
GCM
-
CHS
1 stop8h 01m
Spirit Airlines
Deal found 1/16$338
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:02 pm
CLT
-
GCM
1 stop19h 36m
Multiple Airlines
Sun 2/152:49 pm
GCM
-
CLT
1 stop17h 37m
Multiple Airlines
Deal found 1/17$341
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/77:43 pm
CLT
-
GCM
1 stop18h 10m
Spirit Airlines
Sun 2/152:49 pm
GCM
-
CLT
1 stop17h 37m
Spirit Airlines
Deal found 1/17$342

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 2/10

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Sat 2/14

5:30 pm-10:09 am

1 stop16h 39m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 3/5

5:10 am-12:08 pm

1 stop6h 58m

George Town Owen Roberts Intl

Mon 3/9

2:15 pm-11:01 pm

1 stop7h 46m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 2/19

5:10 am-2:14 pm

1 stop9h 04m

George Town Owen Roberts Intl

Mon 2/23

12:50 pm-11:59 pm

1 stop11h 09m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 4/14

6:30 am-11:24 am

1 stop5h 54m

George Town Owen Roberts Intl

Wed 4/15

12:45 pm-10:08 pm

1 stop8h 23m

$289

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 4/10

5:27 am-11:47 am

1 stop7h 20m

George Town Owen Roberts Intl

Tue 4/14

12:45 pm-10:08 pm

1 stop8h 23m

$289

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 4/11

5:27 am-11:47 am

1 stop7h 20m

George Town Owen Roberts Intl

Wed 4/15

12:45 pm-10:08 pm

1 stop8h 23m

$289

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 1/30

6:10 am-2:45 pm

2 stops8h 35m

George Town Owen Roberts Intl

Sun 2/1

3:45 pm-9:48 am

2 stops18h 03m

$298

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 4/11

8:07 am-12:20 pm

1 stop5h 13m

George Town Owen Roberts Intl

Thu 4/16

1:40 pm-10:41 pm

1 stop8h 01m

$334

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 3/19

6:00 am-12:57 pm

1 stop7h 57m

George Town Owen Roberts Intl

Sun 3/22

1:52 pm-2:27 pm

1 stop23h 35m

$346

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 5/27

3:35 pm-11:30 am

1 stop20h 55m

George Town Owen Roberts Intl

Mon 6/1

12:25 pm-2:57 pm

1 stop25h 32m

$355

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/17

Showing 1-10 of 37 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $332). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $519). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 6h 58m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $332). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $519). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Cayman Islands

Discover the top airline that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$642FlexibilityNo cancel feeOn-time71%

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