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Cayman Islands

$85+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This Mytrip deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:00 amSAV - GCM
1 stop6h 45mMultiple Airlines
Thu 12/182:40 pmGCM - SAV
1 stop8h 38mMultiple Airlines
Deal found 12/6$270
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:30 amCHS - GCM
1 stop5h 06mDelta
Wed 12/311:52 pmGCM - CHS
1 stop6h 47mDelta
Deal found 12/7$286
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:18 pmCHS - GCM
1 stop18h 37mSpirit Airlines
Thu 1/82:49 pmGCM - CHS
1 stop26h 47mSpirit Airlines
Deal found 12/8$313
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amCHS - GCM
1 stop8h 25mAmerican Airlines
Wed 12/317:30 amGCM - CHS
2 stops14h 41mAmerican Airlines
Deal found 12/8$316
This Priceline deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:00 amCLT - GCM
1 stop6h 45mSpirit Airlines
Sun 12/212:40 pmGCM - CLT
1 stop5h 53mSpirit Airlines
Deal found 12/7$340
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:42 pmCLT - GCM
1 stop19h 53mMultiple Airlines
Tue 12/237:00 amGCM - CLT
1 stop13h 09mMultiple Airlines
Deal found 12/7$352
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:25 amCHS - GCM
2 stops31h 20mMultiple Airlines
Thu 1/82:49 pmGCM - CHS
1 stop26h 47mMultiple Airlines
Deal found 12/8$360
This Mytrip deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:55 pmCLT - GCM
2 stops16h 50mSpirit Airlines
Sat 12/205:56 pmGCM - CLT
1 stop5h 33mSpirit Airlines
Deal found 12/6$363
This Mytrip deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:34 pmCLT - GCM
2 stops16h 11mSpirit Airlines
Sun 12/282:40 pmGCM - CLT
1 stop5h 53mSpirit Airlines
Deal found 12/6$369
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:38 pmCLT - GCM
1 stop19h 17mMultiple Airlines
Tue 12/237:00 amGCM - CLT
1 stop8h 56mMultiple Airlines
Deal found 12/8$376
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:18 pmCHS - GCM
1 stop18h 37mSpirit Airlines
Thu 1/12:40 pmGCM - CHS
1 stop6h 43mSpirit Airlines
Deal found 12/8$379
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:18 pmCHS - GCM
1 stop18h 37mMultiple Airlines
Tue 1/611:30 amGCM - CHS
2 stops52h 40mMultiple Airlines
Deal found 12/8$384

Find flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated December 8, 2025.

Round-trip from

$235
(FlightHub)

One-way from

$85
(Priceline)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/28

7:30 am-12:29 pm

1 stop4h 59m

George Town Owen Roberts Intl

Sat 3/7

12:25 pm-7:56 pm

1 stop7h 31m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Wed 1/21

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Wed 1/28

2:25 pm-11:44 pm

1 stop9h 19m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 12/25

7:30 am-12:36 pm

1 stop5h 06m

George Town Owen Roberts Intl

Wed 12/31

1:52 pm-8:39 pm

1 stop6h 47m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Wed 1/21

6:10 am-8:20 pm

2 stops14h 10m

George Town Owen Roberts Intl

Wed 1/28

8:50 am-11:07 pm

2 stops14h 17m

$291

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 1/20

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Sun 1/25

2:50 pm-12:32 pm

1 stop21h 42m

$293

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 1/20

6:10 am-8:20 pm

2 stops14h 10m

George Town Owen Roberts Intl

Sun 1/25

3:45 pm-9:48 am

2 stops18h 03m

$296

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Sat 1/3

9:06 am-4:55 pm

1 stop7h 49m

George Town Owen Roberts Intl

Sat 1/10

2:34 pm-5:38 pm

1 stop27h 04m

$302

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 12/25

7:00 am-3:25 pm

1 stop8h 25m

George Town Owen Roberts Intl

Wed 12/31

7:30 am-10:11 pm

2 stops14h 41m

$316

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 1/7

2:57 pm-11:35 am

1 stop20h 38m

George Town Owen Roberts Intl

Sat 1/17

2:34 pm-12:40 am

1 stop10h 06m

$349

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 1/22

6:00 am-1:53 pm

1 stop7h 53m

George Town Owen Roberts Intl

Sun 1/25

2:49 pm-9:30 am

2 stops18h 41m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 36 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $347). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 5h 06m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $347). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$604FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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