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Cayman Islands

$92+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This Expedia deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:30 amCLT - GCM
1 stop26h 55mMultiple Airlines
Sun 1/42:40 pmGCM - CLT
1 stop8h 49mMultiple Airlines
Deal found 12/29$435
This Expedia deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:30 amCLT - GCM
1 stop26h 55mMultiple Airlines
Sat 1/35:56 pmGCM - CLT
1 stop5h 33mMultiple Airlines
Deal found 12/28$465
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:08 pmCHS - GCM
1 stop15h 53mAmerican Airlines
Sun 1/412:50 pmGCM - CHS
1 stop11h 55mAmerican Airlines
Deal found 12/29$519
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:38 pmCLT - GCM
1 stop16h 07mSpirit Airlines
Sun 1/42:40 pmGCM - CLT
2 stops29h 59mSpirit Airlines
Deal found 12/29$559
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:05 amCHS - GCM
2 stops33h 00mMultiple Airlines
Sun 1/42:40 pmGCM - CHS
1 stop6h 43mMultiple Airlines
Deal found 12/29$567
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:25 amCHS - GCM
2 stops31h 20mMultiple Airlines
Sun 1/42:40 pmGCM - CHS
1 stop6h 43mMultiple Airlines
Deal found 12/27$575
This FlightHub deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:00 amCLT - GCM
1 stop6h 45mSpirit Airlines
Sun 1/42:40 pmGCM - CLT
1 stop8h 49mSpirit Airlines
Deal found 12/28$577
This Mytrip deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:57 pmCLT - GCM
3 stops22h 48mSpirit Airlines
Sat 1/35:56 pmGCM - CLT
1 stop5h 33mSpirit Airlines
Deal found 12/28$608
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:00 amCLT - GCM
1 stop6h 35mUnited Airlines
Sat 1/35:30 pmGCM - CLT
1 stop6h 29mUnited Airlines
Deal found 12/28$1,260
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amCLT - GCM
1 stop10h 35mUnited Airlines
Sat 1/32:50 pmGCM - CLT
1 stop19h 41mUnited Airlines
Deal found 12/29$1,277
This Gotogate deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:45 pmCHS - GCM
2 stops16h 40mAir Canada
Sun 1/41:30 pmGCM - CHS
2 stops29h 45mAir Canada
Deal found 12/27$3,303

Find flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated December 30, 2025.

Round-trip from

$288
(American Airlines)

One-way from

$92
(Delta)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 1/19

6:00 am-8:20 pm

1 stop14h 20m

George Town Owen Roberts Intl

Wed 1/21

8:50 am-11:58 pm

1 stop15h 08m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 1/24

5:25 am-2:00 pm

1 stop8h 35m

George Town Owen Roberts Intl

Sat 1/31

2:15 pm-10:22 pm

1 stop8h 07m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 1/22

9:27 am-8:20 pm

1 stop10h 53m

George Town Owen Roberts Intl

Mon 1/26

8:50 am-11:58 pm

1 stop15h 08m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 1/20

9:27 am-8:20 pm

1 stop10h 53m

George Town Owen Roberts Intl

Thu 1/22

8:50 am-11:58 pm

1 stop15h 08m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 1/29

7:28 am-8:20 pm

2 stops12h 52m

George Town Owen Roberts Intl

Mon 2/9

3:45 pm-9:48 am

2 stops18h 03m

$293

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 1/30

6:10 am-2:45 pm

2 stops8h 35m

George Town Owen Roberts Intl

Mon 2/2

12:50 pm-11:07 pm

2 stops10h 17m

$293

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 1/24

10:41 am-8:20 pm

2 stops9h 39m

George Town Owen Roberts Intl

Sat 1/31

3:24 pm-11:04 pm

1 stop7h 40m

$293

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Wed 1/28

6:10 am-2:45 pm

2 stops8h 35m

George Town Owen Roberts Intl

Wed 2/4

1:05 pm-11:07 pm

2 stops10h 02m

$293

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 1/21

7:43 pm-1:53 pm

1 stop18h 10m

George Town Owen Roberts Intl

Sun 1/25

2:49 pm-9:47 pm

1 stop6h 58m

$296

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Sun 1/18

8:00 am-1:53 pm

1 stop5h 53m

George Town Owen Roberts Intl

Thu 1/22

2:49 pm-12:22 pm

2 stops21h 33m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 45 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $376). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 8h 35m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $376). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$608FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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