$151+ Cheap flights from South Carolina to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Jul 16 — Jul 231
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Cayman Islands with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to Cayman IslandsExplore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 pm
CLT
- GCM
1 stop27h 27m
Multiple Airlines
Tue 7/2811:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:19 pm
CLT
- GCM
1 stop7h 56m
Multiple Airlines
Wed 9/2311:30 am
GCM
- CLT
1 stop27h 35m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:48 pm
CLT
- GCM
1 stop27h 27m
Multiple Airlines
Tue 7/1411:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Thu 7/304:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 am
CHS
- GCM
1 stop7h 30m
American Airlines
Thu 6/185:12 pm
GCM
- CHS
1 stop5h 47m
American Airlines
Deal found 6/12![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
CHS
- GCM
1 stop7h 30m
American Airlines
Mon 7/65:10 pm
GCM
- CHS
2 stops18h 19m
American Airlines
Deal found 6/14![American Airlines logo]()
$459
This Air Canada deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Sun 11/11:10 pm
GCM
- CLT
1 stop7h 49m
Air Canada
Deal found 6/11![Air Canada logo]()
$459
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1711:04 am
CHS
- GCM
1 stop6h 06m
American Airlines
Fri 7/245:10 pm
GCM
- CHS
1 stop16h 12m
American Airlines
Deal found 6/15![American Airlines logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Thu 7/304:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Sun 7/267:00 am
GCM
- CLT
1 stop9h 12m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:56 pm
CLT
- GCM
1 stop19h 39m
Multiple Airlines
Mon 9/74:45 pm
GCM
- CLT
1 stop23h 29m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$478
This Air Canada deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:20 am
CLT
- GCM
1 stop26h 40m
Air Canada
Sat 11/141:10 pm
GCM
- CLT
1 stop7h 49m
Air Canada
Deal found 6/11![Air Canada logo]()
$481
Best flights from South Carolina to Cayman IslandsDiscover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
Discover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:00 am
CHS
- GCM
1 stop7h 25m
American Airlines
Mon 8/312:33 pm
GCM
- CHS
1 stop8h 30m
American Airlines
Deal found 6/12![American Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:10 am
CHS
- GCM
1 stop7h 29m
Delta
Tue 8/181:04 pm
GCM
- CHS
1 stop6h 40m
Delta
Deal found 6/14![Delta logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Thu 7/234:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$579
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:10 pm
SAV
- GCM
2 stops22h 20m
Southwest
Sun 7/1212:50 pm
GCM
- SAV
2 stops9h 50m
Southwest
Deal found 6/15![Southwest logo]()
$663
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:35 pm
SAV
- GCM
1 stop24h 55m
United Airlines
Fri 11/135:45 pm
GCM
- SAV
1 stop19h 15m
United Airlines
Deal found 6/13![United Airlines logo]()
$759
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am
CHS
- GCM
1 stop6h 00m
American Airlines
Mon 9/1412:36 pm
GCM
- CHS
1 stop7h 30m
American Airlines
Deal found 6/12![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:41 am
CHS
- GCM
1 stop5h 44m
American Airlines
Tue 7/2812:02 pm
GCM
- CHS
1 stop5h 49m
American Airlines
Deal found 6/14![American Airlines logo]()
$449
This Air Canada deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:40 am
GSP
- GCM
2 stops27h 20m
Air Canada
Thu 12/101:10 pm
GCM
- GSP
2 stops32h 01m
Air Canada
Deal found 6/15![Air Canada logo]()
$1,026
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:00 am
CHS
- GCM
1 stop7h 30m
American Airlines
Tue 6/305:12 pm
GCM
- CHS
2 stops15h 55m
American Airlines
Deal found 6/15![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:48 pm
CHS
- GCM
2 stops14h 57m
American Airlines
Tue 11/39:00 am
GCM
- CHS
2 stops8h 42m
American Airlines
Deal found 6/14![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:33 am
CHS
- GCM
2 stops13h 33m
American Airlines
Fri 10/309:25 am
GCM
- CHS
2 stops13h 30m
American Airlines
Deal found 6/15![American Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:45 am
GSP
- GCM
1 stop5h 46m
Delta
Wed 7/1512:56 pm
GCM
- GSP
1 stop6h 19m
Delta
Deal found 6/11![Delta logo]()
$666
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Sun 7/194:45 pm
GCM
- CLT
2 stops16h 11m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$688
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:41 am
CHS
- GCM
1 stop5h 44m
American Airlines
Tue 8/45:10 pm
GCM
- CHS
2 stops19h 06m
American Airlines
Deal found 6/13![American Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:30 am
SAV
- GCM
1 stop6h 55m
Delta
Sat 11/141:50 pm
GCM
- SAV
1 stop6h 57m
Delta
Deal found 6/13![Delta logo]()
$686
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:35 pm
SAV
- GCM
1 stop24h 55m
United Airlines
Mon 11/165:45 pm
GCM
- SAV
1 stop19h 15m
United Airlines
Deal found 6/13![United Airlines logo]()
$759
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
CHS
- GCM
1 stop7h 30m
American Airlines
Mon 7/65:10 pm
GCM
- CHS
2 stops18h 19m
American Airlines
Deal found 6/14![American Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
SAV
- GCM
1 stop5h 25m
Delta
Fri 11/131:50 pm
GCM
- SAV
1 stop10h 09m
Delta
Deal found 6/13![Delta logo]()
$686
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am
GSP
- GCM
1 stop9h 30m
United Airlines
Thu 12/105:45 pm
GCM
- GSP
1 stop28h 01m
United Airlines
Deal found 6/15![United Airlines logo]()
$835
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:59 am
CLT
- GCM
1 stop5h 32m
Delta
Tue 7/1412:56 pm
GCM
- CLT
1 stop10h 02m
Delta
Deal found 6/13![Delta logo]()
$694
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:30 am
CLT
- GCM
1 stop7h 01m
Delta
Fri 7/3112:56 pm
GCM
- CLT
1 stop10h 02m
Delta
Deal found 6/15![Delta logo]()
$697
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:30 am
CLT
- GCM
1 stop7h 01m
Delta
Fri 7/3112:56 pm
GCM
- CLT
1 stop6h 18m
Delta
Deal found 6/13![Delta logo]()
$697
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:25 am
CAE
- GCM
1 stop6h 02m
American Airlines
Wed 9/1612:36 pm
GCM
- CAE
1 stop7h 24m
American Airlines
Deal found 6/14![American Airlines logo]()
$626
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:30 am
SAV
- GCM
1 stop6h 55m
Delta
Fri 11/131:50 pm
GCM
- SAV
1 stop8h 42m
Delta
Deal found 6/13![Delta logo]()
$721
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:30 am
GSP
- GCM
1 stop10h 40m
American Airlines
Wed 8/52:10 pm
GCM
- GSP
1 stop7h 48m
American Airlines
Deal found 6/14![American Airlines logo]()
$636
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:25 am
CLT
- GCM
Nonstop2h 59m
American Airlines
Wed 9/912:36 pm
GCM
- CLT
Nonstop3h 09m
American Airlines
Deal found 6/11![American Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:11 am
SAV
- GCM
2 stops9h 59m
American Airlines
Wed 7/1512:02 pm
GCM
- SAV
2 stops10h 57m
American Airlines
Deal found 6/13![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:00 am
SAV
- GCM
1 stop7h 25m
American Airlines
Wed 8/512:00 pm
GCM
- SAV
1 stop10h 59m
American Airlines
Deal found 6/11![American Airlines logo]()
$666
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:20 pm
GSP
- GCM
2 stops16h 40m
American Airlines
Wed 7/1512:02 pm
GCM
- GSP
1 stop10h 54m
American Airlines
Deal found 6/11![American Airlines logo]()
$676
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:00 pm
CLT
- GCM
1 stop15h 00m
American Airlines
Sat 8/12:19 pm
GCM
- CLT
Nonstop3h 16m
American Airlines
Deal found 6/14![American Airlines logo]()
$681
Last-minute flights from South Carolina to Cayman IslandsDiscover last-minute flight deals from South Carolina to Cayman Islands. Data last updated June 16, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Cayman Islands. Data last updated June 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 am
CHS
- GCM
1 stop7h 30m
American Airlines
Thu 6/185:12 pm
GCM
- CHS
1 stop5h 47m
American Airlines
Deal found 6/12![American Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:10 am
CHS
- GCM
1 stop7h 24m
Delta
Sun 6/2112:59 pm
GCM
- CHS
1 stop10h 37m
Delta
Deal found 6/14![Delta logo]()
$495
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
CHS
- GCM
1 stop7h 30m
American Airlines
Mon 7/65:10 pm
GCM
- CHS
2 stops18h 19m
American Airlines
Deal found 6/14![American Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Mon 7/204:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$500
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:48 pm
CLT
- GCM
1 stop27h 27m
Multiple Airlines
Tue 7/1411:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Tue 7/2111:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1711:04 am
CHS
- GCM
1 stop6h 06m
American Airlines
Fri 7/245:10 pm
GCM
- CHS
1 stop16h 12m
American Airlines
Deal found 6/15![American Airlines logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Thu 7/304:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Thu 7/304:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 pm
CLT
- GCM
1 stop27h 27m
Multiple Airlines
Tue 7/2811:30 am
GCM
- CLT
1 stop28h 42m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Sun 7/267:00 am
GCM
- CLT
1 stop9h 12m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Thu 7/304:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$488
One-way flights from South Carolina to Cayman IslandsSearch for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
Search for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
This Trip.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:19 pm
CLT
- GCM
1 stop7h 56m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:19 pm
CLT
- GCM
1 stop7h 56m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$167
This Air Canada deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:40 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Deal found 6/11![Air Canada logo]()
$169
This Trip.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:48 pm
CLT
- GCM
1 stop22h 17m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:27 am
CHS
- GCM
1 stop10h 48m
American Airlines
Deal found 6/15![American Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:56 pm
CLT
- GCM
1 stop24h 09m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:48 pm
CLT
- GCM
1 stop27h 27m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$189
This Expedia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:20 am
CLT
- GCM
1 stop26h 40m
Air Canada
Deal found 6/11![Air Canada logo]()
$191
This Air Canada deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:20 am
CLT
- GCM
1 stop26h 40m
Air Canada
Deal found 6/15![Air Canada logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:48 pm
CLT
- GCM
1 stop17h 47m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$206
Find flight deals from South Carolina to Cayman Islands
Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated June 16, 2026.
Round-trip from | $422 (Kiwi.com) |
|---|---|
One-way from | $151 (Trip.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 7/27
5:00 am-11:25 am
1 stop7h 25m
George Town Owen Roberts Intl
Mon 8/3
12:33 pm-10:03 pm
1 stop8h 30m
$449
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 8/11
5:10 am-11:39 am
1 stop7h 29m
George Town Owen Roberts Intl
Tue 8/18
1:04 pm-8:44 pm
1 stop6h 40m
$449
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 9/7
6:00 am-11:00 am
1 stop6h 00m
George Town Owen Roberts Intl
Mon 9/14
12:36 pm-9:06 pm
1 stop7h 30m
$449
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 7/21
6:41 am-11:25 am
1 stop5h 44m
George Town Owen Roberts Intl
Tue 7/28
12:02 pm-6:51 pm
1 stop5h 49m
$449
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Fri 6/26
5:00 am-11:30 am
1 stop7h 30m
George Town Owen Roberts Intl
Tue 6/30
5:12 pm-10:07 am
2 stops15h 55m
$454
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 10/27
8:48 pm-10:45 am
2 stops14h 57m
George Town Owen Roberts Intl
Tue 11/3
9:00 am-5:42 pm
2 stops8h 42m
$454
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Fri 10/23
5:33 am-6:06 pm
2 stops13h 33m
George Town Owen Roberts Intl
Fri 10/30
9:25 am-11:55 pm
2 stops13h 30m
$454
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 7/28
6:41 am-11:25 am
1 stop5h 44m
George Town Owen Roberts Intl
Tue 8/4
5:10 pm-1:16 pm
2 stops19h 06m
$454
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Wed 7/1
5:00 am-11:30 am
1 stop7h 30m
George Town Owen Roberts Intl
Mon 7/6
5:10 pm-12:29 pm
2 stops18h 19m
$459
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Thu 7/16
6:48 pm-11:35 am
1 stop17h 47m
George Town Owen Roberts Intl
Thu 7/23
4:45 pm-5:12 pm
1 stop23h 27m
$579
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
CHS-GCM
CLT-GCM
SAV-GCM
GSP-GCM
CAE-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to the Cayman Islands
USSC-KY0
CHS-GCM
CLT-GCM
SAV-GCM
GSP-GCM
What is the cheapest month to book a flight from South Carolina to Cayman Islands?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $286). Flying from South Carolina to Cayman Islands in December is currently the most expensive (average of $622). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Cayman Islands by cabin class
Find flights from South Carolina to Cayman Islands, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Cayman Islands flights
Browse other South Carolina and Cayman Islands flight options. Last updated on June 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top 2 airlines flying from South Carolina to Cayman Islands
Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$675 | FlexibilityNo cancel fee | On-time71% |