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Cayman Islands

$91+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:00 amCHS - GCM
1 stop8h 25mAmerican Airlines
Sat 11/223:36 pmGCM - CHS
1 stop8h 27mAmerican Airlines
Deal found 10/30$286
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:00 amCHS - GCM
1 stop14h 28mAmerican Airlines
Wed 11/263:10 pmGCM - CHS
1 stop19h 32mAmerican Airlines
Deal found 10/29$403
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:30 amCLT - GCM
1 stop26h 55mMultiple Airlines
Sun 11/164:45 pmGCM - CLT
1 stop15h 02mMultiple Airlines
Deal found 10/30$420
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:57 pmCLT - GCM
1 stop20h 38mMultiple Airlines
Mon 1/54:45 pmGCM - CLT
1 stop27h 24mMultiple Airlines
Deal found 10/29$464
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:00 amCLT - GCM
Nonstop2h 57mAmerican Airlines
Sun 11/163:10 pmGCM - CLT
Nonstop3h 05mAmerican Airlines
Deal found 10/30$467
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:34 amCLT - GCM
1 stop10h 41mMultiple Airlines
Mon 1/54:45 pmGCM - CLT
1 stop23h 11mMultiple Airlines
Deal found 10/30$478
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:09 amCLT - GCM
Nonstop2h 56mAmerican Airlines
Sun 11/169:00 amGCM - CLT
1 stop22h 50mAmerican Airlines
Deal found 10/29$489
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:31 amCHS - GCM
3 stops27h 54mMultiple Airlines
Wed 11/265:10 pmGCM - CHS
1 stop14h 16mMultiple Airlines
Deal found 10/30$495
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:11 pmCAE - GCM
1 stop15h 49mAmerican Airlines
Sat 12/204:26 pmGCM - CAE
1 stop7h 42mAmerican Airlines
Deal found 10/29$558
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:06 pmCHS - GCM
1 stop18h 43mAmerican Airlines
Sat 12/273:15 pmGCM - CHS
1 stop6h 56mAmerican Airlines
Deal found 10/30$559
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:06 amCAE - GCM
2 stops7h 04mAmerican Airlines
Sun 12/2112:55 pmGCM - CAE
1 stop6h 38mAmerican Airlines
Deal found 10/30$568
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:58 amSAV - GCM
1 stop9h 30mAmerican Airlines
Thu 11/279:00 amGCM - SAV
1 stop6h 50mAmerican Airlines
Deal found 10/30$575

Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated October 30, 2025.

Round-trip from

$286
(American Airlines)

One-way from

$91
(United Airlines)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 11/15

6:00 am-8:28 pm

1 stop14h 28m

George Town Owen Roberts Intl

Sat 11/22

12:39 pm-9:24 pm

1 stop8h 45m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 1/29

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Sun 2/1

2:50 pm-2:02 pm

1 stop23h 12m

$293

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Wed 1/14

6:10 am-11:26 am

1 stop5h 16m

George Town Owen Roberts Intl

Sat 1/24

3:45 pm-8:47 am

1 stop17h 02m

$293

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 3/10

5:51 am-10:45 am

1 stop5h 54m

George Town Owen Roberts Intl

Wed 3/11

3:15 pm-11:20 pm

1 stop7h 05m

$400

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 11/20

6:00 am-8:28 pm

1 stop14h 28m

George Town Owen Roberts Intl

Wed 11/26

3:10 pm-10:42 am

1 stop19h 32m

$403

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 11/13

9:30 am-12:25 pm

1 stop26h 55m

George Town Owen Roberts Intl

Sun 11/16

4:45 pm-7:47 am

1 stop15h 02m

$420

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 11/13

9:00 am-11:57 am

Nonstop2h 57m

George Town Owen Roberts Intl

Sun 11/16

3:10 pm-6:15 pm

Nonstop3h 05m

$467

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 2/7

11:25 am-2:26 pm

Nonstop3h 01m

George Town Owen Roberts Intl

Sat 2/14

8:45 am-12:15 am

1 stop15h 30m

$476

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 1/5

9:00 am-11:57 am

Nonstop2h 57m

George Town Owen Roberts Intl

Mon 1/12

12:50 pm-10:47 pm

1 stop9h 57m

$476

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 12/29

10:34 am-9:15 pm

1 stop10h 41m

George Town Owen Roberts Intl

Mon 1/5

4:45 pm-3:56 pm

1 stop23h 11m

$478

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 35 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $355). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 4h 50m. Airlines will cover a distance of 1079 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $91 on American Airlines. Other airlines that offer cheap prices include United Airlines from $91 and Spirit Airlines from $108 one-way.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $355). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$600FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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