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Cayman Islands

$181+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated April 30, 2025.

Round-trip from

$489
(Mytrip)

One-way from

$181
(Kiwi.com)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:47 pmCHS - GCM
1 stop15h 13mAmerican Airlines
Sat 11/221:45 pmGCM - CHS
1 stop10h 31mAmerican Airlines
Deal found 4/29$484
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:00 amCLT - GCM
1 stop16h 20mMultiple Airlines
Sun 6/14:45 pmGCM - CLT
1 stop17h 18mMultiple Airlines
Deal found 4/29$489
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:16 pmGSP - GCM
2 stops16h 54mAmerican Airlines
Sat 8/1612:10 pmGCM - GSP
2 stops10h 47mAmerican Airlines
Deal found 4/29$499
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/296:40 amSAV - GCM
1 stop5h 45mDelta
Sat 8/21:10 pmGCM - SAV
1 stop9h 49mDelta
Deal found 4/29$513
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/299:36 pmCHS - GCM
1 stop19h 29mMultiple Airlines
Sun 6/112:40 pmGCM - CHS
2 stops21h 53mMultiple Airlines
Deal found 4/29$529
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:25 pmCLT - GCM
1 stop13h 45mAmerican Airlines
Thu 10/2312:45 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 4/28$530
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:35 amGSP - GCM
1 stop4h 45mDelta
Thu 5/2912:35 pmGCM - GSP
1 stop6h 40mDelta
Deal found 4/28$532
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:30 amCLT - GCM
1 stop7h 07mDelta
Thu 11/272:02 pmGCM - CLT
1 stop9h 52mDelta
Deal found 4/28$540
This Air Canada deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/258:30 amCLT - GCM
1 stop28h 25mAir Canada
Mon 7/1412:50 pmGCM - CLT
1 stop7h 31mAir Canada
Deal found 4/28$584
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/207:00 amCLT - GCM
1 stop6h 30mUnited Airlines
Sat 7/264:45 pmGCM - CLT
1 stop17h 15mUnited Airlines
Deal found 4/28$615
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:40 amCAE - GCM
1 stop6h 51mDelta
Mon 9/2212:53 pmGCM - CAE
1 stop7h 55mDelta
Deal found 4/29$615
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:57 pmCAE - GCM
2 stops18h 13mAmerican Airlines
Sat 9/63:15 pmGCM - CAE
2 stops20h 00mAmerican Airlines
Deal found 4/29$639

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 5/29

6:00 am-9:20 pm

1 stop16h 20m

George Town Owen Roberts Intl

Sun 6/1

4:45 pm-11:03 am

1 stop17h 18m

$489

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 8/9

7:16 pm-11:10 am

2 stops16h 54m

George Town Owen Roberts Intl

Sat 8/16

12:10 pm-11:57 pm

2 stops10h 47m

$499

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

6:40 am-11:25 am

1 stop5h 45m

George Town Owen Roberts Intl

Sat 8/2

1:10 pm-11:59 pm

1 stop9h 49m

$513

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 5/29

9:36 pm-4:05 pm

1 stop19h 29m

George Town Owen Roberts Intl

Sun 6/1

12:40 pm-11:33 am

2 stops21h 53m

$529

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/22

7:35 am-11:20 am

1 stop4h 45m

George Town Owen Roberts Intl

Thu 5/29

12:35 pm-8:15 pm

1 stop6h 40m

$532

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 6/25

8:30 am-11:55 am

1 stop28h 25m

George Town Owen Roberts Intl

Mon 7/14

12:50 pm-9:21 pm

1 stop7h 31m

$584

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 6/25

6:52 am-11:25 am

1 stop5h 33m

George Town Owen Roberts Intl

Tue 7/8

12:40 pm-8:39 pm

1 stop6h 59m

$590

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/20

9:22 am-11:22 am

Nonstop3h 00m

George Town Owen Roberts Intl

Sat 7/26

3:05 pm-7:15 pm

Nonstop3h 10m

$600

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/20

7:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Sat 7/26

4:45 pm-11:00 am

1 stop17h 15m

$615

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Thu 9/18

5:40 am-11:31 am

1 stop6h 51m

George Town Owen Roberts Intl

Mon 9/22

12:53 pm-9:48 pm

1 stop7h 55m

$615

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 22 results
1
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 30, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from South Carolina to Cayman Islands. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
WestJet
7.2
Good
2,823 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Boarding

8.2

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $213 on Air Canada. Other airlines that offer cheap prices include American Airlines from $303 and Delta from $333 one-way.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$579FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$627FlexibilityNo cancel feeOn-timeN/A

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