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Cayman Islands

$88+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This FlightHub deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:00 am
CLT
-
GCM
1 stop7h 53m
Spirit Airlines
Thu 2/122:49 pm
GCM
-
CLT
1 stop9h 07m
Spirit Airlines
Deal found 1/28$234
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
CLT
-
GCM
1 stop7h 20m
Spirit Airlines
Sat 3/211:15 pm
GCM
-
CLT
1 stop10h 23m
Spirit Airlines
Deal found 1/27$256
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
CLT
-
GCM
1 stop7h 20m
Spirit Airlines
Thu 3/191:52 pm
GCM
-
CLT
1 stop5h 31m
Spirit Airlines
Deal found 1/27$264
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:10 am
CHS
-
GCM
1 stop9h 04m
American Airlines
Mon 3/212:58 pm
GCM
-
CHS
1 stop10h 53m
American Airlines
Deal found 1/27$287
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:10 am
CHS
-
GCM
1 stop9h 04m
American Airlines
Mon 2/233:15 pm
GCM
-
CHS
1 stop7h 46m
American Airlines
Deal found 1/28$288
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/65:25 am
CHS
-
GCM
1 stop7h 15m
Delta
Mon 2/92:05 pm
GCM
-
CHS
1 stop8h 02m
Delta
Deal found 1/27$289
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:02 am
CHS
-
GCM
1 stop11h 01m
American Airlines
Thu 4/3012:00 pm
GCM
-
CHS
2 stops19h 31m
American Airlines
Deal found 1/27$294
This FlightHub deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:55 am
CLT
-
GCM
1 stop7h 48m
Spirit Airlines
Sun 3/81:49 pm
GCM
-
CLT
1 stop9h 07m
Spirit Airlines
Deal found 1/28$297
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
CLT
-
GCM
1 stop7h 43m
Spirit Airlines
Sun 4/191:40 pm
GCM
-
CLT
1 stop10h 00m
Spirit Airlines
Deal found 1/27$305
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:00 am
CHS
-
GCM
1 stop7h 15m
United Airlines
Fri 2/132:50 pm
GCM
-
CHS
1 stop23h 02m
United Airlines
Deal found 1/27$317
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:00 am
CLT
-
GCM
1 stop7h 38m
Spirit Airlines
Sat 2/72:34 pm
GCM
-
CLT
1 stop10h 06m
Spirit Airlines
Deal found 1/26$321
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
CLT
-
GCM
1 stop7h 43m
Spirit Airlines
Thu 4/231:40 pm
GCM
-
CLT
1 stop10h 00m
Spirit Airlines
Deal found 1/26$327

Find flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated January 29, 2026.

Round-trip from

$234
(FlightHub)

One-way from

$88
(FlightHub)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 2/8

6:00 am-1:53 pm

1 stop7h 53m

George Town Owen Roberts Intl

Thu 2/12

2:49 pm-11:56 pm

1 stop9h 07m

$276

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 2/23

5:10 am-2:14 pm

1 stop9h 04m

George Town Owen Roberts Intl

Mon 3/2

12:58 pm-11:51 pm

1 stop10h 53m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/28

6:00 am-1:01 pm

1 stop7h 01m

George Town Owen Roberts Intl

Sat 3/7

3:40 pm-11:54 pm

1 stop8h 14m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 3/5

5:10 am-2:14 pm

1 stop9h 04m

George Town Owen Roberts Intl

Mon 3/9

12:00 pm-11:55 pm

1 stop10h 55m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 2/10

5:25 am-12:40 pm

1 stop7h 15m

George Town Owen Roberts Intl

Sat 2/14

1:54 pm-7:56 pm

1 stop6h 02m

$287

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 2/19

5:10 am-2:14 pm

1 stop9h 04m

George Town Owen Roberts Intl

Mon 2/23

3:15 pm-11:01 pm

1 stop7h 46m

$288

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 4/25

5:20 am-12:00 pm

1 stop7h 40m

George Town Owen Roberts Intl

Thu 4/30

1:25 pm-9:55 pm

1 stop7h 30m

$289

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 4/25

5:02 am-3:03 pm

1 stop11h 01m

George Town Owen Roberts Intl

Thu 4/30

12:00 pm-8:31 am

2 stops19h 31m

$294

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 2/10

6:00 am-1:15 pm

1 stop7h 15m

George Town Owen Roberts Intl

Fri 2/13

2:50 pm-1:52 pm

1 stop23h 02m

$317

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 4/16

6:00 am-12:43 pm

1 stop7h 43m

George Town Owen Roberts Intl

Thu 4/23

1:40 pm-12:40 am

1 stop10h 00m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 39 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $288). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $519). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 7h 01m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $288). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $519). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Cayman Islands

Discover the top airline that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$425Average$646FlexibilityNo cancel feeOn-time71%

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