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Cayman Islands

$107+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Apr 2 — Apr 91
Thu 4/2
Thu 4/9
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.

This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
CHS
-
GCM
1 stop7h 40m
Delta
Wed 4/291:25 pm
GCM
-
CHS
1 stop7h 30m
Delta
Deal found 2/27$319
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:33 pm
CHS
-
GCM
2 stops17h 37m
American Airlines
Wed 7/1512:00 pm
GCM
-
CHS
1 stop10h 59m
American Airlines
Deal found 2/27$324
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:21 pm
CHS
-
GCM
2 stops15h 34m
American Airlines
Mon 4/2712:35 pm
GCM
-
CHS
1 stop26h 03m
American Airlines
Deal found 2/28$330
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:21 pm
CHS
-
GCM
2 stops15h 34m
American Airlines
Wed 4/292:05 pm
GCM
-
CHS
1 stop19h 29m
American Airlines
Deal found 2/26$332
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:27 am
CHS
-
GCM
1 stop7h 02m
Delta
Mon 3/91:12 pm
GCM
-
CHS
1 stop10h 04m
Delta
Deal found 3/3$339
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:10 am
CHS
-
GCM
2 stops10h 15m
American Airlines
Mon 3/912:00 pm
GCM
-
CHS
1 stop10h 55m
American Airlines
Deal found 3/3$344
This Air Canada deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:35 pm
CLT
-
GCM
1 stop20h 50m
Air Canada
Mon 6/112:25 pm
GCM
-
CLT
1 stop25h 32m
Air Canada
Deal found 2/26$345
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
CHS
-
GCM
1 stop14h 15m
American Airlines
Sun 3/2211:40 am
GCM
-
CHS
1 stop21h 46m
American Airlines
Deal found 3/2$353
This Mytrip deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:07 am
CHS
-
GCM
1 stop5h 50m
Spirit Airlines
Sat 3/211:15 pm
GCM
-
CHS
1 stop7h 58m
Spirit Airlines
Deal found 3/2$354
This FlightHub deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
CLT
-
GCM
1 stop7h 20m
Spirit Airlines
Sat 3/211:15 pm
GCM
-
CLT
1 stop10h 23m
Spirit Airlines
Deal found 2/26$354
This Air Canada deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:30 am
CLT
-
GCM
1 stop26h 40m
Air Canada
Thu 4/911:55 am
GCM
-
CLT
1 stop8h 05m
Air Canada
Deal found 3/1$365
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
CLT
-
GCM
1 stop7h 57m
Multiple Airlines
Mon 3/234:45 pm
GCM
-
CLT
1 stop18h 22m
Multiple Airlines
Deal found 2/26$370

Find flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated March 3, 2026.

Round-trip from

$319
(Delta)

One-way from

$107
(Delta)

Popular in

February

Cheapest in

January

Average price

$881
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($113 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 7/16

6:50 am-12:30 pm

1 stop6h 40m

George Town Owen Roberts Intl

Wed 7/22

1:35 pm-10:15 pm

1 stop7h 40m

$319

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 4/24

6:25 am-12:00 pm

1 stop6h 35m

George Town Owen Roberts Intl

Mon 4/27

1:25 pm-8:41 pm

1 stop6h 16m

$319

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 4/13

5:20 am-12:00 pm

1 stop7h 40m

George Town Owen Roberts Intl

Mon 4/20

1:25 pm-9:55 pm

1 stop7h 30m

$319

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 5/2

6:00 am-3:05 pm

1 stop10h 05m

George Town Owen Roberts Intl

Tue 5/5

1:35 pm-9:59 pm

1 stop7h 24m

$319

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Fri 4/24

5:20 am-12:00 pm

1 stop7h 40m

George Town Owen Roberts Intl

Wed 4/29

1:25 pm-8:41 pm

1 stop6h 16m

$319

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 5/9

6:00 am-3:05 pm

1 stop10h 05m

George Town Owen Roberts Intl

Tue 5/12

1:35 pm-9:59 pm

1 stop7h 24m

$319

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 4/25

5:20 am-12:00 pm

1 stop7h 40m

George Town Owen Roberts Intl

Thu 4/30

1:25 pm-12:22 am

1 stop9h 57m

$319

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 3/14

9:00 pm-12:57 pm

1 stop16h 57m

George Town Owen Roberts Intl

Wed 3/18

11:30 am-12:07 pm

1 stop23h 37m

$387

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 3/19

6:00 am-12:57 pm

1 stop7h 57m

George Town Owen Roberts Intl

Mon 3/23

4:45 pm-11:53 pm

3 stops30h 08m

$424

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Tue 4/14

7:00 am-4:05 pm

1 stop10h 05m

George Town Owen Roberts Intl

Tue 4/21

11:30 am-9:10 am

3 stops20h 40m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/1

Showing 1-10 of 51 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $287). Flying from South Carolina to Cayman Islands in September is currently the most expensive (average of $564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 7h 40m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $287). Flying from South Carolina to Cayman Islands in September is currently the most expensive (average of $564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$287Average$591FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$289Average$596FlexibilityNo cancel feeOn-time71%

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