Cayman Islands

$143+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Jul 2 — Jul 91
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Cheap flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.

This Orbitz deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:15 am
CLT
-
GCM
1 stop27h 10m
Air Canada
Mon 6/812:25 pm
GCM
-
CLT
1 stop25h 32m
Air Canada
Deal found 5/28$385
This Air Canada deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:15 am
CLT
-
GCM
1 stop27h 10m
Air Canada
Sat 6/610:55 am
GCM
-
CLT
1 stop9h 02m
Air Canada
Deal found 5/28$387
This Air Canada deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:40 pm
CLT
-
GCM
1 stop20h 45m
Air Canada
Sat 9/1212:25 pm
GCM
-
CLT
1 stop25h 32m
Air Canada
Deal found 6/1$407
This Air Canada deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm
CLT
-
GCM
1 stop19h 00m
Air Canada
Sun 11/11:10 pm
GCM
-
CLT
1 stop7h 49m
Air Canada
Deal found 6/2$432
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:48 pm
CLT
-
GCM
1 stop27h 27m
Multiple Airlines
Tue 7/2811:30 am
GCM
-
CLT
1 stop28h 42m
Multiple Airlines
Deal found 5/29$433
This Air Canada deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:15 am
CLT
-
GCM
1 stop27h 10m
Air Canada
Thu 6/1112:25 pm
GCM
-
CLT
1 stop25h 32m
Air Canada
Deal found 5/28$436
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:51 am
CHS
-
GCM
1 stop5h 39m
American Airlines
Fri 6/195:12 pm
GCM
-
CHS
1 stop5h 47m
American Airlines
Deal found 6/1$439
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:50 pm
CHS
-
GCM
1 stop16h 40m
American Airlines
Thu 6/185:12 pm
GCM
-
CHS
1 stop5h 47m
American Airlines
Deal found 5/31$446
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
CHS
-
GCM
1 stop5h 55m
American Airlines
Thu 8/2712:30 pm
GCM
-
CHS
1 stop8h 21m
American Airlines
Deal found 5/28$449
This Orbitz deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
CLT
-
GCM
1 stop19h 05m
Air Canada
Mon 8/2412:25 pm
GCM
-
CLT
1 stop25h 37m
Air Canada
Deal found 6/1$449
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am
CHS
-
GCM
1 stop14h 20m
American Airlines
Sun 11/83:14 pm
GCM
-
CHS
1 stop17h 27m
American Airlines
Deal found 5/31$455
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:48 pm
CLT
-
GCM
1 stop17h 47m
Multiple Airlines
Tue 8/1111:30 am
GCM
-
CLT
1 stop28h 42m
Multiple Airlines
Deal found 5/28$455

Find flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated June 2, 2026.

Round-trip from

$385
(Orbitz)

One-way from

$143
(Air Canada)
From South Carolina to Cayman Islands
One-way flight from South Carolina to Cayman Islands

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 7/13

6:00 am-4:10 pm

1 stop11h 10m

George Town Owen Roberts Intl

Thu 7/16

5:10 pm-11:59 pm

1 stop5h 49m

$439

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 7/25

5:00 am-3:03 pm

1 stop11h 03m

George Town Owen Roberts Intl

Fri 7/31

5:10 pm-11:59 pm

1 stop5h 49m

$439

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 6/16

6:51 am-11:30 am

1 stop5h 39m

George Town Owen Roberts Intl

Fri 6/19

5:12 pm-11:59 pm

1 stop5h 47m

$439

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 7/16

11:04 am-4:10 pm

1 stop6h 06m

George Town Owen Roberts Intl

Thu 7/23

5:10 pm-12:19 pm

2 stops18h 09m

$444

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 8/22

6:00 am-10:55 am

1 stop5h 55m

George Town Owen Roberts Intl

Thu 8/27

12:30 pm-9:51 pm

1 stop8h 21m

$449

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 11/3

6:00 am-8:20 pm

1 stop14h 20m

George Town Owen Roberts Intl

Sun 11/8

3:14 pm-8:41 am

1 stop17h 27m

$455

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sun 11/1

9:27 am-8:20 pm

1 stop10h 53m

George Town Owen Roberts Intl

Fri 11/6

3:14 pm-12:23 am

1 stop9h 09m

$490

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 7/22

6:48 pm-11:35 am

1 stop17h 47m

George Town Owen Roberts Intl

Tue 7/28

11:30 am-6:03 pm

2 stops29h 33m

$531

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Wed 7/1

6:43 am-11:34 am

1 stop5h 51m

George Town Owen Roberts Intl

Tue 7/7

12:56 pm-9:17 pm

1 stop7h 21m

$631

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 11/9

5:30 am-12:25 pm

1 stop6h 55m

George Town Owen Roberts Intl

Fri 11/13

1:50 pm-8:18 pm

1 stop6h 28m

$641

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/29

Showing 1-10 of 38 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $286). Flying from South Carolina to Cayman Islands in July is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 5h 51m. Airlines will cover a distance of 886 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $286). Flying from South Carolina to Cayman Islands in July is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$287Average$455FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$289Average$675FlexibilityNo cancel feeOn-time71%

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