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Cayman Islands

$91+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
ene. 14 — ene. 211
mié. 1/14
mié. 1/21
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 15, 2025.

This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:35 amCHS - GCM
1 stop7h 52mDelta
mié. 12/311:52 pmGCM - CHS
1 stop6h 47mDelta
Deal found 12/14$287
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/319:38 pmCLT - GCM
1 stop16h 07mMultiple Airlines
lun. 1/54:45 pmGCM - CLT
1 stop27h 24mMultiple Airlines
Deal found 12/14$399
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/249:38 pmCLT - GCM
1 stop16h 07mMultiple Airlines
dom. 12/282:40 pmGCM - CLT
1 stop23h 32mMultiple Airlines
Deal found 12/14$408
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/232:57 pmCLT - GCM
1 stop20h 38mMultiple Airlines
dom. 12/282:40 pmGCM - CLT
1 stop23h 32mMultiple Airlines
Deal found 12/14$417
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:44 amCHS - GCM
1 stop5h 13mAmerican Airlines
sáb. 12/273:45 pmGCM - CHS
1 stop17h 02mAmerican Airlines
Deal found 12/15$422
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/307:46 pmCLT - GCM
1 stop20h 19mMultiple Airlines
lun. 1/54:45 pmGCM - CLT
1 stop27h 24mMultiple Airlines
Deal found 12/14$436
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:44 amCHS - GCM
1 stop5h 13mAmerican Airlines
mié. 12/317:30 amGCM - CHS
2 stops14h 41mAmerican Airlines
Deal found 12/14$443
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/169:03 amCLT - GCM
Nonstop2h 56mAmerican Airlines
jue. 12/1812:55 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 12/12$462
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/319:38 pmCLT - GCM
1 stop16h 07mMultiple Airlines
dom. 1/42:40 pmGCM - CLT
1 stop23h 32mMultiple Airlines
Deal found 12/14$485
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/292:57 pmCLT - GCM
1 stop25h 08mMultiple Airlines
lun. 1/54:45 pmGCM - CLT
1 stop27h 24mMultiple Airlines
Deal found 12/14$498
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/278:08 pmCHS - GCM
1 stop15h 49mAmerican Airlines
jue. 1/112:50 pmGCM - CHS
1 stop11h 55mAmerican Airlines
Deal found 12/14$538
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/1411:43 amSAV - GCM
1 stop28h 47mUnited Airlines
jue. 12/182:25 pmGCM - SAV
1 stop9h 30mUnited Airlines
Deal found 12/12$886

Find flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated diciembre 15, 2025.

Round-trip from

$247
(Priceline)

One-way from

$91
(United Airlines)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

jue. 1/29

6:00 am-1:53 pm

1 stop7h 53m

George Town Owen Roberts Intl

jue. 2/5

2:49 pm-12:40 am

1 stop9h 51m

$247

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

sáb. 2/28

6:30 am-12:29 pm

1 stop5h 59m

George Town Owen Roberts Intl

sáb. 3/7

12:25 pm-7:56 pm

1 stop7h 31m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

mié. 3/25

11:06 am-7:15 pm

1 stop9h 09m

George Town Owen Roberts Intl

mar. 3/31

7:45 am-11:59 pm

1 stop15h 14m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

dom. 1/18

6:30 am-12:40 pm

1 stop6h 10m

George Town Owen Roberts Intl

lun. 1/26

2:05 pm-11:55 pm

1 stop9h 50m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

vie. 1/16

6:26 pm-11:18 am

1 stop16h 52m

George Town Owen Roberts Intl

lun. 1/26

2:05 pm-11:55 pm

1 stop9h 50m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

vie. 1/16

7:00 pm-11:00 am

1 stop16h 00m

George Town Owen Roberts Intl

sáb. 1/24

3:25 pm-9:38 pm

1 stop6h 13m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

dom. 1/18

6:30 am-12:40 pm

1 stop6h 10m

George Town Owen Roberts Intl

sáb. 1/24

12:22 pm-7:18 pm

1 stop6h 56m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

dom. 1/18

6:30 am-12:40 pm

1 stop6h 10m

George Town Owen Roberts Intl

jue. 1/22

2:05 pm-11:55 pm

1 stop9h 50m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

sáb. 1/17

5:25 am-11:00 am

1 stop5h 35m

George Town Owen Roberts Intl

lun. 1/26

2:05 pm-8:57 pm

1 stop6h 52m

$286

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

jue. 12/25

8:35 am-2:27 pm

1 stop5h 52m

George Town Owen Roberts Intl

mié. 12/31

3:42 pm-11:58 pm

1 stop8h 16m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 43 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $375). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 5h 59m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $375). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$608FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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