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Cayman Islands

$86+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Gotogate deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:08 amCLT - GCM
1 stop5h 47mSpirit Airlines
Sat 12/275:56 pmGCM - CLT
1 stop5h 33mSpirit Airlines
Deal found 11/22$314
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:58 pmCLT - GCM
1 stop22h 47mMultiple Airlines
Sun 12/142:40 pmGCM - CLT
1 stop23h 32mMultiple Airlines
Deal found 11/24$317
This Mytrip deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:10 pmCLT - GCM
2 stops17h 35mSpirit Airlines
Sun 12/142:40 pmGCM - CLT
1 stop9h 19mSpirit Airlines
Deal found 11/24$323
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:54 amCLT - GCM
1 stop8h 01mMultiple Airlines
Sat 12/275:56 pmGCM - CLT
1 stop15h 43mMultiple Airlines
Deal found 11/24$352
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amCHS - GCM
1 stop8h 25mAmerican Airlines
Sun 12/283:11 pmGCM - CHS
1 stop17h 24mAmerican Airlines
Deal found 11/24$366
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:38 pmCLT - GCM
1 stop19h 17mMultiple Airlines
Wed 12/247:00 amGCM - CLT
1 stop8h 56mMultiple Airlines
Deal found 11/24$374
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:42 pmCLT - GCM
1 stop24h 23mMultiple Airlines
Sun 12/72:40 pmGCM - CLT
1 stop18h 59mMultiple Airlines
Deal found 11/22$388
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:15 amCHS - GCM
1 stop6h 12mDelta
Thu 1/11:52 pmGCM - CHS
1 stop6h 47mDelta
Deal found 11/21$430
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:30 amCHS - GCM
1 stop10h 00mUnited Airlines
Sat 11/292:50 pmGCM - CHS
1 stop12h 25mUnited Airlines
Deal found 11/23$452
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:08 pmCHS - GCM
1 stop15h 49mAmerican Airlines
Sat 12/273:45 pmGCM - CHS
1 stop9h 00mAmerican Airlines
Deal found 11/23$465
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:00 amCHS - GCM
2 stops11h 28mAmerican Airlines
Sat 11/293:18 pmGCM - CHS
1 stop7h 01mAmerican Airlines
Deal found 11/23$495
This Mytrip deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:00 amSAV - GCM
2 stops26h 25mMultiple Airlines
Thu 12/42:40 pmGCM - SAV
1 stop7h 41mMultiple Airlines
Deal found 11/24$508

Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated November 24, 2025.

Round-trip from

$302
(Kiwi.com)

One-way from

$86
(Priceline)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 12/20

11:08 am-4:55 pm

1 stop5h 47m

George Town Owen Roberts Intl

Sat 12/27

5:56 pm-11:29 pm

1 stop5h 33m

$314

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 1/6

5:25 am-12:40 pm

1 stop7h 15m

George Town Owen Roberts Intl

Tue 1/13

2:05 pm-8:55 pm

1 stop6h 50m

$320

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 2/1

7:00 am-1:53 pm

1 stop6h 53m

George Town Owen Roberts Intl

Sun 2/8

2:49 pm-9:47 pm

1 stop6h 58m

$320

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 1/26

5:25 am-12:40 pm

1 stop7h 15m

George Town Owen Roberts Intl

Thu 1/29

2:05 pm-10:07 pm

1 stop8h 02m

$320

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 1/6

6:00 am-8:20 pm

2 stops14h 20m

George Town Owen Roberts Intl

Tue 1/13

8:50 am-11:07 pm

2 stops14h 17m

$325

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 2/2

7:00 am-9:15 pm

1 stop14h 15m

George Town Owen Roberts Intl

Thu 2/5

2:49 pm-8:55 pm

1 stop6h 06m

$326

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 2/1

7:00 am-1:53 pm

1 stop6h 53m

George Town Owen Roberts Intl

Fri 2/6

4:45 pm-12:22 pm

1 stop19h 37m

$349

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 2/2

7:00 am-9:15 pm

1 stop14h 15m

George Town Owen Roberts Intl

Sat 2/7

2:34 pm-12:40 am

1 stop10h 06m

$350

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 2/5

7:00 am-1:53 pm

1 stop6h 53m

George Town Owen Roberts Intl

Mon 2/9

7:00 am-12:22 pm

1 stop5h 22m

$350

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 12/20

8:54 am-4:55 pm

1 stop8h 01m

George Town Owen Roberts Intl

Sat 12/27

5:56 pm-8:33 pm

1 stop26h 37m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/22

Showing 1-10 of 39 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $355). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 5h 47m. Airlines will cover a distance of 1100 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $355). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$600FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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