$165+ Cheap flights from South Carolina to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Cayman Islands with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Cayman Islands
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Cheapest flights from South Carolina to Cayman IslandsExplore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This Air Canada deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:10 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Fri 12/111:10 pm
GCM
- CLT
1 stop7h 56m
Air Canada
Deal found 7/26![Air Canada logo]()
$483
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:58 pm
CLT
- GCM
1 stop22h 37m
Multiple Airlines
Thu 8/277:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:59 pm
CLT
- GCM
1 stop8h 16m
Multiple Airlines
Thu 10/227:00 am
GCM
- CLT
1 stop8h 05m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:32 pm
CHS
- GCM
1 stop14h 51m
American Airlines
Fri 11/68:15 am
GCM
- CHS
1 stop11h 19m
American Airlines
Deal found 7/26![American Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Sun 9/67:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$530
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:10 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Sun 11/291:10 pm
GCM
- CLT
1 stop27h 16m
Air Canada
Deal found 7/26![Air Canada logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:59 pm
CLT
- GCM
1 stop8h 16m
Multiple Airlines
Mon 10/197:00 am
GCM
- CLT
1 stop8h 05m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:59 pm
CLT
- GCM
1 stop8h 16m
Multiple Airlines
Mon 10/197:00 am
GCM
- CLT
1 stop8h 05m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$539
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
CLT
- GCM
1 stop22h 37m
Multiple Airlines
Sun 9/134:45 pm
GCM
- CLT
1 stop27h 29m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$540
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Fri 8/287:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:44 am
CLT
- GCM
2 stops29h 21m
Multiple Airlines
Thu 10/227:00 am
GCM
- CLT
1 stop8h 05m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$547
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:27 am
CLT
- GCM
1 stop10h 48m
Multiple Airlines
Fri 9/257:00 am
GCM
- CLT
1 stop13h 14m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$550
Best flights from South Carolina to Cayman IslandsDiscover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:15 am
CHS
- GCM
1 stop6h 24m
Delta
Mon 9/141:00 pm
GCM
- CHS
1 stop9h 59m
Delta
Deal found 7/24![Delta logo]()
$529
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:32 pm
CHS
- GCM
1 stop14h 51m
American Airlines
Fri 11/68:15 am
GCM
- CHS
1 stop11h 19m
American Airlines
Deal found 7/25![American Airlines logo]()
$529
This Justfly.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:10 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Sat 11/281:10 pm
GCM
- CLT
1 stop27h 16m
Air Canada
Deal found 7/23![Air Canada logo]()
$612
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:11 pm
GSP
- GCM
2 stops28h 54m
Multiple Airlines
Thu 10/1512:40 pm
GCM
- GSP
1 stop24h 45m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$614
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
SAV
- GCM
1 stop9h 30m
United Airlines
Mon 11/165:45 pm
GCM
- SAV
1 stop19h 12m
United Airlines
Deal found 7/27![United Airlines logo]()
$623
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am
CHS
- GCM
1 stop7h 10m
Delta
Thu 10/2212:55 pm
GCM
- CHS
1 stop10h 04m
Delta
Deal found 7/24![Delta logo]()
$529
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:41 pm
CHS
- GCM
2 stops16h 14m
American Airlines
Fri 9/1812:36 pm
GCM
- CHS
2 stops10h 07m
American Airlines
Deal found 7/28![American Airlines logo]()
$534
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am
CHS
- GCM
1 stop4h 40m
Delta
Sun 10/1812:55 pm
GCM
- CHS
1 stop10h 04m
Delta
Deal found 7/24![Delta logo]()
$529
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:55 am
CLT
- GCM
1 stop27h 15m
Air Canada
Sat 11/281:10 pm
GCM
- CLT
1 stop27h 16m
Air Canada
Deal found 7/28![Air Canada logo]()
$642
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:13 pm
GSP
- GCM
1 stop20h 52m
Multiple Airlines
Fri 8/2111:25 am
GCM
- GSP
1 stop7h 08m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$658
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:20 am
SAV
- GCM
1 stop5h 03m
American Airlines
Mon 11/1612:55 pm
GCM
- SAV
1 stop11h 04m
American Airlines
Deal found 7/27![American Airlines logo]()
$636
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:35 pm
GSP
- GCM
1 stop15h 30m
American Airlines
Fri 12/43:14 pm
GCM
- GSP
1 stop8h 43m
American Airlines
Deal found 7/26![American Airlines logo]()
$650
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/107:00 pm
SAV
- GCM
1 stop18h 45m
United Airlines
Thu 1/142:50 pm
GCM
- SAV
1 stop26h 35m
United Airlines
Deal found 7/27![United Airlines logo]()
$806
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:55 am
CLT
- GCM
1 stop5h 45m
Delta
Thu 10/1512:55 pm
GCM
- CLT
1 stop6h 19m
Delta
Deal found 7/28![Delta logo]()
$671
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:30 am
CLT
- GCM
Nonstop3h 00m
American Airlines
Sun 10/1812:35 pm
GCM
- CLT
Nonstop3h 05m
American Airlines
Deal found 7/23![American Airlines logo]()
$667
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:30 am
CAE
- GCM
1 stop5h 10m
Delta
Sun 9/201:00 pm
GCM
- CAE
1 stop7h 11m
Delta
Deal found 7/24![Delta logo]()
$679
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
SAV
- GCM
1 stop8h 10m
American Airlines
Tue 8/2512:30 pm
GCM
- SAV
1 stop5h 40m
American Airlines
Deal found 7/25![American Airlines logo]()
$671
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:45 am
CLT
- GCM
1 stop5h 55m
Delta
Mon 10/1212:55 pm
GCM
- CLT
1 stop10h 04m
Delta
Deal found 7/26![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:22 am
CLT
- GCM
Nonstop3h 02m
American Airlines
Sat 12/1212:55 pm
GCM
- CLT
Nonstop3h 01m
American Airlines
Deal found 7/24![American Airlines logo]()
$677
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
CLT
- GCM
1 stop6h 40m
Delta
Mon 10/1212:55 pm
GCM
- CLT
1 stop10h 04m
Delta
Deal found 7/27![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:28 pm
CAE
- GCM
1 stop15h 59m
American Airlines
Sun 9/2012:36 pm
GCM
- CAE
2 stops10h 27m
American Airlines
Deal found 7/24![American Airlines logo]()
$687
This Air Canada deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:30 am
SAV
- GCM
2 stops29h 40m
Air Canada
Thu 1/141:10 pm
GCM
- SAV
2 stops34h 15m
Air Canada
Deal found 7/25![Air Canada logo]()
$1,713
Last-minute flights from South Carolina to Cayman IslandsDiscover last-minute flight deals from South Carolina to Cayman Islands. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Cayman Islands. Data last updated July 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:13 pm
GSP
- GCM
1 stop20h 52m
Multiple Airlines
Fri 8/2111:25 am
GCM
- GSP
1 stop7h 08m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$658
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:48 pm
CLT
- GCM
2 stops21h 02m
Multiple Airlines
Fri 8/214:45 pm
GCM
- CLT
2 stops22h 41m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:19 pm
GSP
- GCM
2 stops18h 36m
American Airlines
Fri 8/2112:00 pm
GCM
- GSP
2 stops8h 50m
American Airlines
Deal found 7/27![American Airlines logo]()
$790
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
SAV
- GCM
1 stop8h 10m
American Airlines
Tue 8/2512:30 pm
GCM
- SAV
1 stop5h 40m
American Airlines
Deal found 7/25![American Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:58 pm
CLT
- GCM
1 stop22h 37m
Multiple Airlines
Thu 8/277:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:30 am
CLT
- GCM
Nonstop2h 57m
American Airlines
Thu 8/2712:30 pm
GCM
- CLT
Nonstop3h 10m
American Airlines
Deal found 7/23![American Airlines logo]()
$657
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Fri 8/287:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$544
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:03 pm
CLT
- GCM
Nonstop2h 57m
American Airlines
Mon 8/2412:30 pm
GCM
- CLT
Nonstop3h 10m
American Airlines
Deal found 7/25![American Airlines logo]()
$676
This Air Canada deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:40 am
CHS
- GCM
2 stops24h 45m
Air Canada
Sat 8/2910:40 am
GCM
- CHS
1 stop22h 33m
Air Canada
Deal found 7/25![Air Canada logo]()
$1,164
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Sat 9/511:25 am
GCM
- CLT
2 stops32h 18m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:21 pm
CLT
- GCM
2 stops19h 14m
Multiple Airlines
Mon 8/317:00 am
GCM
- CLT
1 stop8h 46m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$600
One-way flights from South Carolina to Cayman IslandsSearch for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Air Canada deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:15 am
CLT
- GCM
1 stop27h 10m
Air Canada
Deal found 7/25![Air Canada logo]()
$165
This Air Canada deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:40 pm
CLT
- GCM
1 stop19h 05m
Air Canada
Deal found 7/23![Air Canada logo]()
$180
This Trip.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:27 am
CLT
- GCM
1 stop10h 48m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:58 pm
CLT
- GCM
1 stop22h 37m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:00 pm
CLT
- GCM
1 stop21h 35m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:58 pm
CLT
- GCM
1 stop8h 17m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:10 am
CHS
- GCM
2 stops9h 32m
American Airlines
Deal found 7/25![American Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:44 am
CLT
- GCM
2 stops29h 21m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:27 pm
CLT
- GCM
1 stop17h 08m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:59 pm
CLT
- GCM
1 stop14h 36m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$216
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:48 pm
CHS
- GCM
2 stops16h 12m
American Airlines
Deal found 7/27![American Airlines logo]()
$217
This Air Canada deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:10 pm
CLT
- GCM
1 stop19h 00m
Air Canada
Deal found 7/26![Air Canada logo]()
$217
Find flight deals from South Carolina to Cayman Islands
Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated July 28, 2026.
Round-trip from | $483 (Air Canada) |
|---|---|
One-way from | $165 (Air Canada) |
Popular in | February |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 9/7
6:15 am-11:39 am
1 stop6h 24m
George Town Owen Roberts Intl
Mon 9/14
1:00 pm-11:59 pm
1 stop9h 59m
$529
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Sun 11/1
8:32 pm-11:23 am
1 stop14h 51m
George Town Owen Roberts Intl
Fri 11/6
8:15 am-7:34 pm
1 stop11h 19m
$529
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 10/12
5:30 am-11:40 am
1 stop7h 10m
George Town Owen Roberts Intl
Thu 10/22
12:55 pm-11:59 pm
1 stop10h 04m
$529
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Mon 10/12
8:00 am-11:40 am
1 stop4h 40m
George Town Owen Roberts Intl
Sun 10/18
12:55 pm-11:59 pm
1 stop10h 04m
$529
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Fri 9/11
7:41 pm-10:55 am
2 stops16h 14m
George Town Owen Roberts Intl
Fri 9/18
12:36 pm-11:43 pm
2 stops10h 07m
$534
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Sat 11/21
5:10 pm-12:10 pm
1 stop19h 00m
George Town Owen Roberts Intl
Sat 11/28
1:10 pm-4:26 pm
1 stop27h 16m
$612
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Fri 10/2
12:11 pm-4:05 pm
2 stops28h 54m
George Town Owen Roberts Intl
Thu 10/15
12:40 pm-2:25 pm
1 stop24h 45m
$614
SavannahGeorge Town
SAV - GCM
SAVGCM
Savannah/Hilton Head
Tue 11/10
7:00 am-4:30 pm
1 stop9h 30m
George Town Owen Roberts Intl
Mon 11/16
5:45 pm-12:57 pm
1 stop19h 12m
$623
SavannahGeorge Town
SAV - GCM
SAVGCM
Savannah/Hilton Head
Tue 11/10
6:20 am-11:23 am
1 stop5h 03m
George Town Owen Roberts Intl
Mon 11/16
12:55 pm-11:59 pm
1 stop11h 04m
$636
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Tue 11/24
8:55 am-12:10 pm
1 stop27h 15m
George Town Owen Roberts Intl
Sat 11/28
1:10 pm-4:26 pm
1 stop27h 16m
$642
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
CLT-GCM
GSP-GCM
SAV-GCM
CHS-GCM
CAE-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to the Cayman Islands
USSC-KY0
CLT-GCM
GSP-GCM
SAV-GCM
CHS-GCM
What is the cheapest month to book a flight from South Carolina to Cayman Islands?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $309). Flying from South Carolina to Cayman Islands in September is currently the most expensive (average of $999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Alternative routes for South Carolina to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Cayman Islands by cabin class
Find flights from South Carolina to Cayman Islands, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Cayman Islands flights
Browse other South Carolina and Cayman Islands flight options. Last updated on July 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top 2 airlines flying from South Carolina to Cayman Islands
Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$690 | FlexibilityNo cancel fee | On-time71% |