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Cayman Islands

$110+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:55 amCHS - GCM
2 stops25h 50mSpirit Airlines
Sat 12/205:56 pmGCM - CHS
1 stop27h 27mSpirit Airlines
Deal found 11/14$333
This American Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:40 amCHS - GCM
1 stop5h 20mAmerican Airlines
Mon 12/153:45 pmGCM - CHS
1 stop9h 01mAmerican Airlines
Deal found 11/14$340
This Mytrip deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:00 amCLT - GCM
1 stop4h 45mMultiple Airlines
Tue 12/237:00 amGCM - CLT
1 stop13h 09mMultiple Airlines
Deal found 11/15$392
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:38 pmCLT - GCM
1 stop16h 07mMultiple Airlines
Wed 1/711:30 amGCM - CLT
1 stop8h 39mMultiple Airlines
Deal found 11/16$393
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:38 pmCLT - GCM
1 stop16h 07mMultiple Airlines
Sun 12/282:40 pmGCM - CLT
2 stops17h 19mMultiple Airlines
Deal found 11/16$400
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:38 pmCLT - GCM
1 stop16h 07mSpirit Airlines
Sun 12/282:40 pmGCM - CLT
1 stop5h 53mSpirit Airlines
Deal found 11/16$401
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:00 amCLT - GCM
1 stop6h 45mMultiple Airlines
Mon 12/154:45 pmGCM - CLT
1 stop19h 56mMultiple Airlines
Deal found 11/15$410
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:34 pmCLT - GCM
2 stops16h 11mSpirit Airlines
Sat 12/275:56 pmGCM - CLT
1 stop5h 33mSpirit Airlines
Deal found 11/16$422
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:34 pmCLT - GCM
2 stops19h 21mMultiple Airlines
Wed 12/247:00 amGCM - CLT
1 stop8h 56mMultiple Airlines
Deal found 11/16$453
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:55 amCLT - GCM
1 stop4h 50mMultiple Airlines
Fri 12/51:30 pmGCM - CLT
2 stops24h 32mMultiple Airlines
Deal found 11/16$467
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:08 pmCHS - GCM
1 stop15h 49mAmerican Airlines
Sat 12/2712:50 pmGCM - CHS
1 stop19h 57mAmerican Airlines
Deal found 11/15$475
This Mytrip deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:55 amCHS - GCM
2 stops24h 30mMultiple Airlines
Sat 12/205:56 pmGCM - CHS
2 stops19h 14mMultiple Airlines
Deal found 11/14$492

Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated November 17, 2025.

Round-trip from

$333
(Kiwi.com)

One-way from

$110
(Kiwi.com)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/28

5:27 am-11:00 am

1 stop5h 33m

George Town Owen Roberts Intl

Sat 3/7

3:07 pm-9:04 pm

1 stop5h 57m

$340

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 12/13

7:00 am-3:22 pm

1 stop8h 22m

George Town Owen Roberts Intl

Sat 12/20

12:47 pm-7:28 pm

1 stop6h 41m

$340

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 1/8

6:10 am-8:20 pm

2 stops14h 10m

George Town Owen Roberts Intl

Sun 1/11

3:45 pm-9:48 am

2 stops18h 03m

$350

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 1/24

7:00 am-1:38 pm

1 stop6h 38m

George Town Owen Roberts Intl

Fri 1/30

1:30 pm-4:17 pm

1 stop26h 47m

$386

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 12/18

9:00 am-1:45 pm

1 stop4h 45m

George Town Owen Roberts Intl

Tue 12/23

7:00 am-8:09 pm

1 stop13h 09m

$392

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 3/10

5:51 am-10:45 am

1 stop5h 54m

George Town Owen Roberts Intl

Wed 3/11

3:15 pm-11:20 pm

1 stop7h 05m

$400

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 4/13

9:30 am-11:10 am

1 stop26h 40m

George Town Owen Roberts Intl

Fri 4/17

12:30 pm-4:20 pm

1 stop26h 50m

$405

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Fri 1/9

6:56 pm-1:38 pm

1 stop18h 42m

George Town Owen Roberts Intl

Mon 1/12

7:00 am-12:58 pm

1 stop5h 58m

$407

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 12/13

11:55 am-1:45 pm

3 stops25h 50m

George Town Owen Roberts Intl

Sat 12/20

5:56 pm-1:10 pm

2 stops19h 14m

$413

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 12/20

9:34 pm-1:45 pm

2 stops16h 11m

George Town Owen Roberts Intl

Sat 12/27

5:56 pm-11:29 pm

1 stop5h 33m

$422

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Showing 1-10 of 31 results
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Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $355). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cayman Islands?

    Departing from South Carolina to Cayman Islands will take you 5h 33m. Airlines will cover a distance of 943 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $355). Flying from South Carolina to Cayman Islands in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$600FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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