$133+ Cheap flights from South Carolina to the Cayman Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to Cayman IslandsExplore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:45 pm
CLT
- GCM
1 stop5h 30m
Multiple Airlines
Mon 6/84:45 pm
GCM
- CLT
1 stop23h 29m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$397
This Travelocity deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:40 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Mon 9/1412:25 pm
GCM
- CLT
1 stop25h 32m
Air Canada
Deal found 4/29![Air Canada logo]()
$413
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:30 am
CHS
- GCM
1 stop7h 00m
United Airlines
Fri 5/81:35 pm
GCM
- CHS
1 stop7h 24m
United Airlines
Deal found 4/30![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:51 am
CHS
- GCM
2 stops9h 16m
American Airlines
Sat 6/134:07 pm
GCM
- CHS
2 stops17h 00m
American Airlines
Deal found 4/26![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:45 am
CHS
- GCM
2 stops10h 26m
American Airlines
Mon 6/812:33 pm
GCM
- CHS
1 stop10h 26m
American Airlines
Deal found 4/28![American Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:20 pm
CLT
- GCM
1 stop18h 45m
Multiple Airlines
Mon 6/224:45 pm
GCM
- CLT
1 stop15h 31m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:00 am
CHS
- GCM
2 stops12h 11m
American Airlines
Sun 6/145:12 pm
GCM
- CHS
2 stops15h 55m
American Airlines
Deal found 4/26![American Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:20 am
CHS
- GCM
1 stop7h 40m
Delta
Mon 5/111:19 pm
GCM
- CHS
1 stop7h 33m
Delta
Deal found 4/30![Delta logo]()
$439
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:13 pm
CHS
- GCM
1 stop17h 31m
American Airlines
Fri 5/82:10 pm
GCM
- CHS
2 stops17h 21m
American Airlines
Deal found 4/30![American Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2612:55 pm
CLT
- GCM
1 stop23h 40m
Multiple Airlines
Sat 8/18:50 am
GCM
- CLT
1 stop7h 43m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1812:55 pm
CLT
- GCM
1 stop9h 20m
Multiple Airlines
Mon 6/224:45 pm
GCM
- CLT
1 stop15h 31m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$450
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:55 pm
CLT
- GCM
1 stop9h 20m
Multiple Airlines
Fri 7/314:45 pm
GCM
- CLT
1 stop23h 27m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$463
Best flights from South Carolina to Cayman IslandsDiscover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from South Carolina to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
CHS
- GCM
1 stop11h 10m
American Airlines
Mon 7/275:10 pm
GCM
- CHS
1 stop5h 49m
American Airlines
Deal found 4/26![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
CHS
- GCM
1 stop7h 35m
United Airlines
Sat 6/132:40 pm
GCM
- CHS
1 stop8h 16m
United Airlines
Deal found 4/26![United Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1812:55 pm
CLT
- GCM
1 stop9h 20m
Multiple Airlines
Mon 6/224:45 pm
GCM
- CLT
1 stop15h 31m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$450
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
GSP
- GCM
1 stop7h 14m
Delta
Sat 5/231:19 pm
GCM
- GSP
1 stop9h 29m
Delta
Deal found 4/30![Delta logo]()
$491
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
CHS
- GCM
1 stop6h 00m
American Airlines
Fri 8/2812:30 pm
GCM
- CHS
1 stop9h 24m
American Airlines
Deal found 4/26![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:51 am
CHS
- GCM
2 stops9h 16m
American Airlines
Sat 6/134:07 pm
GCM
- CHS
2 stops17h 00m
American Airlines
Deal found 4/26![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:45 am
CHS
- GCM
1 stop5h 45m
American Airlines
Mon 6/812:33 pm
GCM
- CHS
1 stop8h 32m
American Airlines
Deal found 4/28![American Airlines logo]()
$424
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:00 am
CLT
- GCM
2 stops11h 05m
Multiple Airlines
Mon 6/1512:25 pm
GCM
- CLT
1 stop25h 32m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$538
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:43 pm
CHS
- GCM
2 stops15h 07m
American Airlines
Tue 9/151:20 pm
GCM
- CHS
2 stops17h 50m
American Airlines
Deal found 4/29![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:45 am
GSP
- GCM
1 stop6h 09m
Delta
Sat 5/161:19 pm
GCM
- GSP
1 stop5h 54m
Delta
Deal found 4/29![Delta logo]()
$610
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:48 pm
CLT
- GCM
3 stops46h 12m
Multiple Airlines
Mon 6/812:25 pm
GCM
- CLT
3 stops24h 46m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:00 am
GSP
- GCM
2 stops9h 03m
American Airlines
Sat 5/2311:55 am
GCM
- GSP
2 stops10h 57m
American Airlines
Deal found 4/29![American Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:44 am
GSP
- GCM
1 stop6h 47m
Delta
Wed 7/1512:56 pm
GCM
- GSP
1 stop6h 22m
Delta
Deal found 4/26![Delta logo]()
$662
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:30 am
CLT
- GCM
1 stop7h 10m
Delta
Mon 10/1212:55 pm
GCM
- CLT
1 stop6h 23m
Delta
Deal found 4/29![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:20 am
GSP
- GCM
1 stop7h 11m
American Airlines
Fri 5/1512:35 pm
GCM
- GSP
1 stop10h 22m
American Airlines
Deal found 4/29![American Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:30 am
CLT
- GCM
1 stop7h 04m
Delta
Mon 6/2212:59 pm
GCM
- CLT
1 stop8h 01m
Delta
Deal found 4/26![Delta logo]()
$761
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:49 pm
GSP
- GCM
2 stops16h 01m
American Airlines
Mon 9/211:20 pm
GCM
- GSP
2 stops17h 46m
American Airlines
Deal found 4/30![American Airlines logo]()
$655
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:20 pm
GSP
- GCM
1 stop20h 10m
American Airlines
Sat 8/152:10 pm
GCM
- GSP
1 stop7h 58m
American Airlines
Deal found 4/29![American Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:15 am
SAV
- GCM
1 stop7h 20m
United Airlines
Sat 6/202:40 pm
GCM
- SAV
1 stop8h 23m
United Airlines
Deal found 4/29![United Airlines logo]()
$1,409
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 am
SAV
- GCM
1 stop11h 11m
American Airlines
Sun 6/215:12 pm
GCM
- SAV
1 stop5h 47m
American Airlines
Deal found 4/30![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:00 am
CLT
- GCM
Nonstop3h 00m
American Airlines
Mon 10/1212:40 pm
GCM
- CLT
Nonstop3h 05m
American Airlines
Deal found 4/27![American Airlines logo]()
$697
This WestJet deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:00 pm
SAV
- GCM
2 stops24h 45m
WestJet
Tue 8/251:45 pm
GCM
- SAV
2 stops26h 53m
WestJet
Deal found 4/26![WestJet logo]()
$3,513
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:05 pm
CLT
- GCM
Nonstop2h 58m
American Airlines
Sat 8/111:56 am
GCM
- CLT
1 stop8h 30m
American Airlines
Deal found 4/30![American Airlines logo]()
$732
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:00 am
CAE
- GCM
1 stop7h 30m
American Airlines
Fri 6/1912:33 pm
GCM
- CAE
1 stop8h 26m
American Airlines
Deal found 4/28![American Airlines logo]()
$821
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:45 pm
CAE
- GCM
2 stops17h 50m
United Airlines
Fri 6/191:35 pm
GCM
- CAE
3 stops19h 21m
United Airlines
Deal found 4/28![United Airlines logo]()
$5,182
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:13 pm
SAV
- GCM
1 stop15h 48m
American Airlines
Sat 6/2011:55 am
GCM
- SAV
2 stops11h 04m
American Airlines
Deal found 4/29![American Airlines logo]()
$1,873
Last-minute flights from South Carolina to Cayman IslandsDiscover last-minute flight deals from South Carolina to Cayman Islands. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Cayman Islands. Data last updated May 1, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:30 am
CHS
- GCM
1 stop7h 00m
United Airlines
Fri 5/81:35 pm
GCM
- CHS
1 stop7h 24m
United Airlines
Deal found 4/30![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:13 pm
CHS
- GCM
1 stop17h 31m
American Airlines
Fri 5/82:10 pm
GCM
- CHS
2 stops17h 21m
American Airlines
Deal found 4/30![American Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:21 pm
CHS
- GCM
2 stops15h 34m
American Airlines
Thu 5/72:10 pm
GCM
- CHS
2 stops17h 21m
American Airlines
Deal found 4/30![American Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:21 pm
CHS
- GCM
1 stop16h 10m
American Airlines
Tue 5/512:00 pm
GCM
- CHS
1 stop11h 24m
American Airlines
Deal found 4/30![American Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:20 am
CHS
- GCM
1 stop7h 40m
Delta
Mon 5/111:19 pm
GCM
- CHS
1 stop7h 33m
Delta
Deal found 4/30![Delta logo]()
$439
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:48 pm
GSP
- GCM
2 stops16h 43m
American Airlines
Sat 5/1611:55 am
GCM
- GSP
1 stop5h 20m
American Airlines
Deal found 4/30![American Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
GSP
- GCM
1 stop7h 14m
Delta
Sat 5/231:19 pm
GCM
- GSP
1 stop9h 29m
Delta
Deal found 4/29![Delta logo]()
$491
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:00 am
GSP
- GCM
2 stops9h 03m
American Airlines
Sat 5/2311:55 am
GCM
- GSP
2 stops10h 57m
American Airlines
Deal found 4/29![American Airlines logo]()
$496
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:00 pm
CLT
- GCM
2 stops33h 15m
Multiple Airlines
Wed 5/2711:30 am
GCM
- CLT
1 stop23h 13m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$519
This Air Canada deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:35 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Mon 6/112:25 pm
GCM
- CLT
1 stop25h 32m
Air Canada
Deal found 4/26![Air Canada logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:12 am
CLT
- GCM
2 stops9h 53m
Multiple Airlines
Sun 5/314:45 pm
GCM
- CLT
1 stop17h 58m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:45 pm
CLT
- GCM
1 stop5h 30m
Multiple Airlines
Sun 5/317:00 am
GCM
- CLT
1 stop27h 43m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$403
One-way flights from South Carolina to Cayman IslandsSearch for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from South Carolina to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Travelocity deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:15 am
CLT
- GCM
1 stop27h 10m
Air Canada
Deal found 4/26![Air Canada logo]()
$133
This Air Canada deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/219:15 am
CLT
- GCM
1 stop27h 10m
Air Canada
Deal found 4/26![Air Canada logo]()
$138
This Trip.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:45 pm
CLT
- GCM
1 stop19h 50m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$146
This Trip.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:33 pm
CLT
- GCM
1 stop18h 02m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:45 pm
CLT
- GCM
1 stop5h 50m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:33 pm
CLT
- GCM
1 stop22h 32m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:45 pm
CLT
- GCM
1 stop19h 50m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:45 pm
CLT
- GCM
1 stop19h 50m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:33 pm
CLT
- GCM
1 stop22h 32m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$170
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:40 am
CAE
- GCM
1 stop6h 14m
Delta
Deal found 4/28![Delta logo]()
$376
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
CAE
- GCM
2 stops8h 10m
American Airlines
Deal found 4/28![American Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:38 pm
CAE
- GCM
3 stops17h 52m
United Airlines
Deal found 4/28![United Airlines logo]()
$2,889
Find flight deals from South Carolina to Cayman Islands
Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated May 1, 2026.
Round-trip from | $397 (Kiwi.com) |
|---|---|
One-way from | $133 (Travelocity) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Thu 7/23
6:00 am-4:10 pm
1 stop11h 10m
George Town Owen Roberts Intl
Mon 7/27
5:10 pm-11:59 pm
1 stop5h 49m
$419
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Sat 6/6
6:00 am-12:35 pm
1 stop7h 35m
George Town Owen Roberts Intl
Sat 6/13
2:40 pm-11:56 pm
1 stop8h 16m
$419
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Fri 8/21
6:00 am-11:00 am
1 stop6h 00m
George Town Owen Roberts Intl
Fri 8/28
12:30 pm-10:54 pm
1 stop9h 24m
$419
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Sat 6/6
6:51 am-3:07 pm
2 stops9h 16m
George Town Owen Roberts Intl
Sat 6/13
4:07 pm-10:07 am
2 stops17h 00m
$424
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Wed 6/3
6:45 am-11:30 am
1 stop5h 45m
George Town Owen Roberts Intl
Mon 6/8
12:33 pm-10:05 pm
1 stop8h 32m
$424
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Wed 9/9
8:43 pm-10:50 am
2 stops15h 07m
George Town Owen Roberts Intl
Tue 9/15
1:20 pm-8:10 am
2 stops17h 50m
$429
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Thu 6/18
12:55 pm-9:15 pm
1 stop9h 20m
George Town Owen Roberts Intl
Mon 6/22
4:45 pm-9:16 am
1 stop15h 31m
$450
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Sat 5/16
5:40 am-11:54 am
1 stop7h 14m
George Town Owen Roberts Intl
Sat 5/23
1:19 pm-11:48 pm
1 stop9h 29m
$491
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Sat 5/16
7:00 am-3:03 pm
2 stops9h 03m
George Town Owen Roberts Intl
Sat 5/23
11:55 am-11:52 pm
2 stops10h 57m
$496
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Sat 6/13
6:00 am-4:05 pm
2 stops11h 05m
George Town Owen Roberts Intl
Mon 6/15
12:25 pm-2:57 pm
1 stop25h 32m
$538
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
CLT-GCM
CAE-GCM
CHS-GCM
GSP-GCM
SAV-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to the Cayman Islands
USSC-KY0
CLT-GCM
CAE-GCM
CHS-GCM
GSP-GCM
What is the cheapest month to book a flight from South Carolina to Cayman Islands?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $286). Flying from South Carolina to Cayman Islands in July is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Cayman Islands by cabin class
Find flights from South Carolina to Cayman Islands, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Cayman Islands flights
Browse other South Carolina and Cayman Islands flight options. Last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top 2 airlines flying from South Carolina to Cayman Islands
Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$643 | FlexibilityNo cancel fee | On-time71% |