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Cayman Islands

$146+ Cheap flights from Missouri to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Jul 30 — Aug 61
Wed 7/30
Wed 8/6
1 adult, Economy
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Cheap flight deals from Missouri to Cayman Islands

Keep the following information in mind while searching for Missouri to Cayman Islands flight deals. Data was last updated July 25, 2025.

Round-trip from

$396
(Delta)

One-way from

$146
(American Airlines)

Popular in

August

Cheapest in

July

Average price

$484
From Missouri to Cayman Islands
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One-way flight from Missouri to Cayman Islands
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High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Missouri to Cayman Islands

Cheapest flights from Missouri to Cayman Islands
Explore the most affordable flight options available from Missouri to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2025.

This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 amMCI - GCM
1 stop5h 37mDelta
Wed 12/172:02 pmGCM - MCI
1 stop10h 55mDelta
Deal found 7/24$396
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:35 pmMCI - GCM
2 stops16h 35mAmerican Airlines
Wed 10/1512:10 pmGCM - MCI
2 stops10h 41mAmerican Airlines
Deal found 7/23$400
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/48:20 amSTL - GCM
1 stop7h 10mUnited Airlines
Sat 11/82:50 pmGCM - STL
1 stop7h 50mUnited Airlines
Deal found 7/24$425
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:59 pmSTL - GCM
2 stops19h 11mAmerican Airlines
Sat 10/113:05 pmGCM - STL
1 stop8h 13mAmerican Airlines
Deal found 7/22$427
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:00 amSTL - GCM
1 stop5h 37mDelta
Sat 11/222:02 pmGCM - STL
1 stop8h 57mDelta
Deal found 7/22$466
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:10 amMCI - GCM
1 stop7h 20mUnited Airlines
Mon 11/105:45 pmGCM - MCI
1 stop16h 44mUnited Airlines
Deal found 7/23$506
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/72:55 pmMCI - GCM
2 stops21h 00mMultiple Airlines
Sun 9/147:00 amGCM - MCI
3 stops40h 07mMultiple Airlines
Deal found 7/24$804
This Mytrip deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/161:00 pmSTL - GCM
3 stops31h 20mMultiple Airlines
Sun 11/237:00 amGCM - STL
3 stops12h 36mMultiple Airlines
Deal found 7/22$867
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:40 amMCI - GCM
1 stop5h 55mSouthwest
Fri 11/281:30 pmGCM - MCI
1 stop10h 05mSouthwest
Deal found 7/23$996
This FlightHub deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:36 amMCI - GCM
2 stops23h 44mAir Canada
Fri 11/281:30 pmGCM - MCI
2 stops20h 38mAir Canada
Deal found 7/24$1,022

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2025.
Use the filters below to find and compare flights from Missouri to the Cayman Islands that are best for you.

Fly from

Missouri

Fly to

Cayman Islands

Route

Depart

Return

Price

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Wed 11/19

6:00 am-12:37 pm

1 stop5h 37m

George Town Owen Roberts Intl

Wed 12/17

2:02 pm-11:57 pm

1 stop10h 55m

$396

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sat 10/11

6:35 pm-11:10 am

2 stops16h 35m

George Town Owen Roberts Intl

Wed 10/15

12:10 pm-10:51 pm

2 stops10h 41m

$400

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 9/27

3:59 pm-11:10 am

2 stops19h 11m

George Town Owen Roberts Intl

Sat 10/11

3:05 pm-11:18 pm

1 stop8h 13m

$427

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Thu 11/6

8:10 am-4:30 pm

1 stop7h 20m

George Town Owen Roberts Intl

Mon 11/10

5:45 pm-9:29 am

1 stop16h 44m

$506

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sun 9/7

2:55 pm-11:55 am

2 stops21h 00m

George Town Owen Roberts Intl

Sun 9/14

7:00 am-11:07 pm

3 stops40h 07m

$804

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 7/27

7:11 pm-11:22 am

1 stop16h 11m

George Town Owen Roberts Intl

Fri 8/1

12:37 pm-9:42 pm

1 stop9h 05m

$804

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Thu 11/20

5:40 am-12:35 pm

1 stop5h 55m

George Town Owen Roberts Intl

Fri 11/28

1:30 pm-10:35 pm

1 stop10h 05m

$996

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Thu 11/20

11:36 am-12:20 pm

2 stops23h 44m

George Town Owen Roberts Intl

Fri 11/28

1:30 pm-9:08 am

2 stops20h 38m

$1,022

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 7/27

9:09 am-12:30 pm

2 stops27h 21m

George Town Owen Roberts Intl

Fri 8/1

1:35 pm-10:40 am

2 stops21h 05m

$1,059

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 7/27

1:00 pm-9:20 pm

3 stops32h 20m

George Town Owen Roberts Intl

Thu 7/31

12:40 pm-9:52 am

2 stops21h 12m

$1,098

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 12 results
1
2

Best time to book a flight from Missouri to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to the Cayman Islands

What is the cheapest month to book a flight from Missouri to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to KY?

Find hourly flight availability from Missouri to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated July 25, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to the Cayman Islands have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,967 reviews
Southwest
8.0
Very good
4,235 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,876 reviews
Southwest
8.0
Very good
4,235 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,235 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Air Canada
7.1
Good
9,788 reviews
Southwest
8.0
Very good
4,235 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Missouri to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Missouri to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Cayman Islands.

  • Can I find deals for business class flights from Missouri to Cayman Islands?

    Yes. Cheapflights offers flight deals from Missouri to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Cayman Islands (average of $467). Flying from Missouri to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Cayman Islands

Discover the top 4 airlines that operate flights from Missouri to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$238Average$602FlexibilityNo cancel feeOn-time69%
DeltaCheapest$266Average$587FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$439Average$605FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$483Average$619FlexibilityNo cancel feeOn-time63%

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