$367+ Cheap flights from Panama to Cabo San Lucas, Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SJD
Oct 22 — Oct 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama to Cabo San Lucas with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Cabo San Lucas
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to Cabo San LucasExplore the most affordable flight options available from Panama to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from Panama to Cabo San Lucas. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:25 am -
Nonstop5h 05m
Sat 10/171:44 pm -
Nonstop5h 00m
Deal found 9/20![Copa Airlines logo]()
$424
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:25 am -
Nonstop5h 13m
Thu 12/31:47 pm -
Nonstop4h 57m
Deal found 9/21![Copa Airlines logo]()
$483
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:25 am -
Nonstop5h 05m
Mon 10/191:44 pm -
Nonstop5h 00m
Deal found 9/20![Copa Airlines logo]()
$553
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/269:25 am -
Nonstop5h 16m
Mon 1/41:42 pm -
Nonstop5h 02m
Deal found 9/18![Copa Airlines logo]()
$633
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:53 am -
1 stop9h 11m
Tue 10/137:47 pm -
1 stop8h 14m
Deal found 9/20![Multiple Airlines logo]()
$648
This Super.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:47 pm -
1 stop9h 48m
Thu 12/37:20 pm -
1 stop16h 26m
Deal found 9/21![Aeromexico logo]()
$673
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:28 pm -
1 stop11h 53m
Mon 10/197:47 pm -
1 stop8h 14m
Deal found 9/20![Multiple Airlines logo]()
$683
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:53 am -
1 stop9h 11m
Sun 10/187:47 pm -
1 stop8h 14m
Deal found 9/17![Multiple Airlines logo]()
$686
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:29 am -
1 stop11h 35m
Mon 10/263:38 pm -
1 stop14h 28m
Deal found 9/18![Multiple Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:50 pm -
1 stop25h 03m
Mon 12/283:38 pm -
1 stop19h 55m
Deal found 9/18![Multiple Airlines logo]()
$725
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:45 am -
1 stop8h 49m
Mon 11/307:27 am -
2 stops10h 51m
Deal found 9/21![Multiple Airlines logo]()
$727
This Booking.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:10 pm -
2 stops24h 50m
Thu 12/33:38 pm -
2 stops23h 37m
Deal found 9/21![Multiple Airlines logo]()
$734
Best flights from Panama to Cabo San LucasDiscover carefully curated flight deals from Panama to Cabo San Lucas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from Panama to Cabo San Lucas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:25 am -
Nonstop5h 05m
Sat 10/171:44 pm -
Nonstop5h 00m
Deal found 9/20![Copa Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:53 am -
1 stop9h 11m
Sun 10/187:47 pm -
1 stop8h 14m
Deal found 9/17![Multiple Airlines logo]()
$686
This FlightHub deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:47 pm -
1 stop29h 47m
Sat 11/219:53 am -
1 stop25h 53m
Deal found 9/17![Aeromexico logo]()
$799
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:41 pm -
2 stops21h 06m
Sat 11/213:39 pm -
2 stops25h 59m
Deal found 9/20![United Airlines logo]()
$956
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:25 am -
Nonstop5h 05m
Mon 10/191:44 pm -
Nonstop5h 00m
Deal found 9/20![Copa Airlines logo]()
$553
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:05 pm -
1 stop18h 16m
Mon 10/191:20 pm -
2 stops14h 41m
Deal found 9/20![Multiple Airlines logo]()
$775
This FlightHub deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:47 pm -
1 stop29h 47m
Thu 11/57:20 pm -
1 stop16h 26m
Deal found 9/20![Aeromexico logo]()
$848
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:47 pm -
2 stops32h 14m
Sat 11/73:38 pm -
1 stop20h 08m
Deal found 9/18![Multiple Airlines logo]()
$793
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:25 am -
Nonstop5h 05m
Sat 10/101:44 pm -
Nonstop5h 00m
Deal found 9/21![Copa Airlines logo]()
$823
This Priceline deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:47 pm -
1 stop29h 47m
Mon 11/304:00 pm -
1 stop14h 05m
Deal found 9/21![Multiple Airlines logo]()
$867
Last-minute flights from Panama to Cabo San LucasDiscover last-minute flight deals from Panama to Cabo San Lucas. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Cabo San Lucas. Data last updated September 22, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:30 pm -
2 stops24h 13m
Tue 9/2911:52 am -
2 stops29h 39m
Deal found 9/17![United Airlines logo]()
$1,709
One-way flights from Panama to Cabo San LucasSearch for one-way flight options from Panama to Cabo San Lucas. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from Panama to Cabo San Lucas. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:05 pm -
1 stop29h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:05 pm -
1 stop29h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:05 pm -
1 stop18h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:05 pm -
1 stop18h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/262:46 pm -
1 stop25h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$395
This SmartFares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:05 pm -
1 stop9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Aeromexico logo]()
$422
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:47 pm -
1 stop29h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Aeromexico logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:31 pm -
2 stops21h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$460
This FlightHub deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:05 pm -
1 stop19h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Aeromexico logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:05 pm -
3 stops30h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$504
Find flight deals from Panama to Cabo San Lucas
Keep the following information in mind while searching for Panama to Cabo San Lucas flight deals. Data was last updated September 22, 2026.
Round-trip from | $424 (Copa Airlines) |
|---|---|
One-way from | $367 (Kiwi.com) |
Popular in | October |
Cheapest in | March |
Average price | $377 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Cabo San Lucas that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Panama to Cabo San Lucas that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Fri 2/26
2:46 pm-1:54 pm
1 stop25h 08m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$395
Quickest round-trip
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Mon 10/12
9:25 am-12:30 pm
Nonstop5h 05m
San José del Cabo Los Cabos
Sat 10/17
1:44 pm-8:44 pm
Nonstop5h 00m
$424
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Fri 11/13
9:31 pm-4:31 pm
2 stops21h 00m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$460
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Tue 10/6
3:05 pm-8:30 am
1 stop19h 25m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$468
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Thu 10/8
3:05 pm-7:29 pm
3 stops30h 24m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$504
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Thu 10/15
9:25 am-12:30 pm
Nonstop5h 05m
San José del Cabo Los Cabos
Mon 10/19
1:44 pm-8:44 pm
Nonstop5h 00m
$553
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Tue 10/6
10:25 am-7:04 pm
2 stops10h 39m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$637
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Thu 10/15
11:53 am-7:04 pm
1 stop9h 11m
San José del Cabo Los Cabos
Sun 10/18
7:47 pm-6:01 am
1 stop8h 14m
$686
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Thu 10/15
3:05 pm-7:21 am
1 stop18h 16m
San José del Cabo Los Cabos
Mon 10/19
1:20 pm-6:01 am
2 stops14h 41m
$775
Panama CitySan José del Cabo
PTY Panama City Tocumen Intl - SJD San José del Cabo Los Cabos
PTYSJD
Panama City Tocumen Intl
Mon 11/2
2:47 pm-9:01 pm
2 stops32h 14m
San José del Cabo Los Cabos
Sat 11/7
3:38 pm-1:46 pm
1 stop20h 08m
$793
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Panama to Cabo San Lucas
Have a flexible travel schedule? Discover the best time to fly to Cabo San Lucas from Panama with our price prediction graph.
PTY-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Cabo San Lucas
PA0-C4B
PTY-SJD
What is the cheapest time of day to fly from PA to C4B?
Find hourly flight availability from Panama to Cabo San Lucas. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Cabo San Lucas as you normally would.
Reviews of airlines servicing Cabo San Lucas
Get insights into the airlines that provide service to Cabo San Lucas. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cabo San Lucas. Reviews last updated September 22, 2026.
Get a feel of what it's like to fly with Copa Airlines from Panama to Cabo San Lucas by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama to Cabo San Lucas. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Complete your trip
Complete your trip to Cabo San Lucas by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Cabo San Lucas by cabin class
Find flights from Panama to Cabo San Lucas, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Cabo San Lucas flights
Browse other Panama and Cabo San Lucas flight options. Last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Panama to Cabo San Lucas flights
Consider these flights traveling from Panama to Cabo San Lucas.
Top airline flying from Panama to Cabo San Lucas
Discover the top airline that operate flights from Panama to Cabo San Lucas. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$347 | Average$390 | FlexibilityNo cancel fee | On-time70% |