$143+ Cheap flights from Sioux Falls to Buffalo (FSD - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — BUF
May 24 — May 311
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Buffalo with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Sioux Falls to BuffaloExplore the most affordable flight options available from Sioux Falls to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Sioux Falls to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:53 am
FSD
- BUF
1 stop6h 34m
Delta
Sat 7/47:45 pm
BUF
- FSD
1 stop4h 27m
Delta
Deal found 4/20![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:30 am
FSD
- BUF
1 stop4h 48m
United Airlines
Sat 5/911:02 am
BUF
- FSD
1 stop4h 36m
United Airlines
Deal found 4/19![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:45 pm
FSD
- BUF
1 stop6h 22m
American Airlines
Sat 7/48:02 am
BUF
- FSD
2 stops9h 52m
American Airlines
Deal found 4/20![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:07 pm
FSD
- BUF
1 stop4h 34m
United Airlines
Sun 7/55:58 pm
BUF
- FSD
1 stop5h 09m
United Airlines
Deal found 4/19![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:46 pm
FSD
- BUF
1 stop6h 21m
American Airlines
Tue 7/74:15 pm
BUF
- FSD
2 stops8h 55m
American Airlines
Deal found 4/19![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/284:46 pm
FSD
- BUF
1 stop6h 21m
American Airlines
Sat 7/48:02 am
BUF
- FSD
1 stop4h 37m
American Airlines
Deal found 4/20![American Airlines logo]()
$488
Best flights from Sioux Falls to BuffaloDiscover carefully curated flight deals from Sioux Falls to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Sioux Falls to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:53 am
FSD
- BUF
1 stop6h 34m
Delta
Sat 7/47:45 pm
BUF
- FSD
1 stop4h 27m
Delta
Deal found 4/20![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:30 am
FSD
- BUF
2 stops10h 05m
United Airlines
Sun 5/107:00 am
BUF
- FSD
1 stop4h 45m
United Airlines
Deal found 4/21![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:04 pm
FSD
- BUF
2 stops8h 19m
American Airlines
Tue 7/78:02 am
BUF
- FSD
2 stops9h 52m
American Airlines
Deal found 4/19![American Airlines logo]()
$460
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:30 am
FSD
- BUF
1 stop4h 48m
United Airlines
Sat 5/911:02 am
BUF
- FSD
2 stops10h 18m
United Airlines
Deal found 4/19![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:07 pm
FSD
- BUF
1 stop4h 34m
United Airlines
Sun 7/55:58 pm
BUF
- FSD
1 stop5h 09m
United Airlines
Deal found 4/19![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:49 pm
FSD
- BUF
1 stop5h 55m
American Airlines
Sat 7/256:00 am
BUF
- FSD
1 stop6h 39m
American Airlines
Deal found 4/22![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:59 pm
FSD
- BUF
1 stop4h 11m
American Airlines
Mon 10/126:26 am
BUF
- FSD
1 stop6h 00m
American Airlines
Deal found 4/21![American Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:07 pm
FSD
- BUF
1 stop4h 34m
United Airlines
Fri 7/315:52 pm
BUF
- FSD
1 stop5h 15m
United Airlines
Deal found 4/23![United Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:42 pm
FSD
- BUF
2 stops10h 14m
American Airlines
Sun 7/56:19 am
BUF
- FSD
2 stops11h 00m
American Airlines
Deal found 4/19![American Airlines logo]()
$669
Last-minute flights from Sioux Falls to BuffaloDiscover last-minute flight deals from Sioux Falls to Buffalo. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Buffalo. Data last updated April 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:41 pm
FSD
- BUF
1 stop8h 38m
American Airlines
Wed 4/293:01 pm
BUF
- FSD
1 stop5h 14m
American Airlines
Deal found 4/23![American Airlines logo]()
$828
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:30 am
FSD
- BUF
1 stop4h 48m
United Airlines
Sat 5/911:02 am
BUF
- FSD
1 stop4h 36m
United Airlines
Deal found 4/19![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:30 am
FSD
- BUF
2 stops9h 40m
United Airlines
Sun 5/106:10 am
BUF
- FSD
2 stops9h 28m
United Airlines
Deal found 4/21![United Airlines logo]()
$687
One-way flights from Sioux Falls to BuffaloSearch for one-way flight options from Sioux Falls to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Sioux Falls to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 pm
FSD
- BUF
1 stop22h 57m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$143
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/254:46 pm
FSD
- BUF
1 stop6h 21m
American Airlines
Deal found 4/20![American Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:53 pm
FSD
- BUF
2 stops9h 09m
Delta
Deal found 4/19![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:16 am
FSD
- BUF
2 stops11h 43m
United Airlines
Deal found 4/22![United Airlines logo]()
$403
Find flight deals from Sioux Falls to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $367 (Delta) |
One-way from | $143 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Sioux Falls to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Sat 6/27
10:53 am-6:27 pm
1 stop6h 34m
Buffalo
Sat 7/4
7:45 pm-11:12 pm
1 stop4h 27m
$367
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Wed 5/6
7:30 am-6:35 pm
2 stops10h 05m
Buffalo
Sun 5/10
7:00 am-10:45 am
1 stop4h 45m
$374
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Tue 5/5
7:30 am-1:18 pm
1 stop4h 48m
Buffalo
Sat 5/9
11:02 am-8:20 pm
2 stops10h 18m
$374
Quickest round-trip
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Mon 6/29
3:07 pm-8:41 pm
1 stop4h 34m
Buffalo
Sun 7/5
5:58 pm-10:07 pm
1 stop5h 09m
$385
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Wed 7/1
12:04 pm-9:23 pm
2 stops8h 19m
Buffalo
Tue 7/7
8:02 am-4:54 pm
2 stops9h 52m
$460
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Sun 7/19
4:49 pm-11:44 pm
1 stop5h 55m
Buffalo
Sat 7/25
6:00 am-11:39 am
1 stop6h 39m
$559
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Fri 10/9
5:59 pm-11:10 pm
1 stop4h 11m
Buffalo
Mon 10/12
6:26 am-11:26 am
1 stop6h 00m
$604
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Mon 7/27
3:07 pm-8:41 pm
1 stop4h 34m
Buffalo
Fri 7/31
5:52 pm-10:07 pm
1 stop5h 15m
$661
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Mon 6/29
12:42 pm-11:56 pm
2 stops10h 14m
Buffalo
Sun 7/5
6:19 am-4:19 pm
2 stops11h 00m
$669
Cheapest one-way
Sioux FallsBuffalo
FSD - BUF
FSDBUF
Sioux Falls Joe Foss Field
Thu 8/13
7:10 pm-7:07 pm
1 stop22h 57m
$143
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Buffalo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Sioux Falls with our price prediction graph.
FSD-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 24, 2026.
Peruse reviews from past customers who have flown with American Airlines from Sioux Falls to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Entertainment
6.9
Overall
7.1
Crew
7.9
Food
6.4
Boarding
7.5
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Comfort
7.2
Entertainment
6.9
Overall
7.1
Crew
7.9
Food
6.4
Boarding
7.5
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 24, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Sioux Falls to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Buffalo flights
Browse other Sioux Falls and Buffalo flight options. Last updated on April 24, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on April 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Sioux Falls to Buffalo
Discover the top airline that operate flights from Sioux Falls to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$377 | FlexibilityNo cancel fee | On-time71% |