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$192+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Santo Domingo to Buffalo

Best flights from Santo Domingo to Buffalo
Discover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/154:42 pmSDQ - BUF
1 stop19h 38mMultiple Airlines
Fri 1/168:58 pmBUF - SDQ
2 stops17h 37mMultiple Airlines
Deal found 12/9$399
This Booking.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/154:42 pmSDQ - BUF
1 stop19h 38mFrontier
Fri 1/168:58 pmBUF - SDQ
1 stop15h 24mFrontier
Deal found 12/9$415
This JetBlue deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:01 amSDQ - BUF
1 stop9h 29mJetBlue
Sun 1/257:00 amBUF - SDQ
1 stop11h 49mJetBlue
Deal found 12/9$463
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/224:18 pmSDQ - BUF
2 stops22h 56mUnited Airlines
Sun 1/258:30 amBUF - SDQ
2 stops14h 16mUnited Airlines
Deal found 12/9$471
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/156:00 amSDQ - BUF
2 stops10h 34mAmerican Airlines
Fri 1/166:53 pmBUF - SDQ
2 stops18h 07mAmerican Airlines
Deal found 12/9$480

Find flight deals from Santo Domingo to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$399
(Kiwi.com)

One-way from

$192
(American Airlines)
Provider with most accurate pricing for Santo Domingo Las Americas-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Buffalo flights.
Search Deals
From Santo Domingo Las Americas to Buffalo
Search Deals
One-way flight from Santo Domingo Las Americas to Buffalo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Santo Domingo

Fly to

Buffalo

Route

Depart

Return

Price

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/15

4:42 pm-11:20 am

1 stop19h 38m

Buffalo

Fri 1/16

8:58 pm-3:35 pm

2 stops17h 37m

$399

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/15

4:42 pm-11:20 am

1 stop19h 38m

Buffalo

Fri 1/16

8:58 pm-1:22 pm

1 stop15h 24m

$415

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/22

6:01 am-2:30 pm

1 stop9h 29m

Buffalo

Sun 1/25

7:00 am-7:49 pm

1 stop11h 49m

$463

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/22

4:18 pm-2:14 pm

2 stops22h 56m

Buffalo

Sun 1/25

8:30 am-11:46 pm

2 stops14h 16m

$471

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/15

6:00 am-3:34 pm

2 stops10h 34m

Buffalo

Fri 1/16

6:53 pm-2:00 pm

2 stops18h 07m

$480

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/29

3:00 pm-11:41 pm

2 stops9h 41m

$192

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/29

7:31 am-2:58 pm

1 stop8h 27m

$204

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/1

7:13 am-11:09 pm

1 stop16h 56m

$247

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/29

3:35 pm-12:44 pm

3 stops22h 09m

$248

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 1/8

4:33 pm-12:00 pm

1 stop20h 27m

$252

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 15 results
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Compare providers for flights from Santo Domingo to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Buffalo in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Buffalo?

    Departing from Santo Domingo to Buffalo will take you 9h 29m. The distance between Santo Domingo and Buffalo is about 1773 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Buffalo.

  • Can I find deals for business class flights from Santo Domingo to Buffalo?

    Yes. Cheapflights offers flight deals from Santo Domingo to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Alternative routes for Santo Domingo to Buffalo

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