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$181+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Santo Domingo to Buffalo

Cheapest flights from Santo Domingo to Buffalo
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amSDQ - BUF
2 stops17h 49mAmerican Airlines
Wed 12/35:24 pmBUF - SDQ
2 stops18h 04mAmerican Airlines
Deal found 10/27$359
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:04 pmSDQ - BUF
1 stop15h 56mJetBlue
Wed 12/36:45 amBUF - SDQ
1 stop6h 46mJetBlue
Deal found 10/27$463
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:14 pmSDQ - BUF
2 stops17h 48mAmerican Airlines
Sun 11/307:03 pmBUF - SDQ
2 stops16h 12mAmerican Airlines
Deal found 10/28$517
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:35 pmSDQ - BUF
2 stops29h 14mFrontier
Sun 12/281:37 pmBUF - SDQ
1 stop20h 43mFrontier
Deal found 10/29$606
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:45 amSDQ - BUF
1 stop13h 34mDelta
Sun 11/3011:19 amBUF - SDQ
1 stop13h 17mDelta
Deal found 10/28$661
This Trip.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:07 amSDQ - BUF
1 stop7h 28mJetBlue
Sun 12/281:55 pmBUF - SDQ
1 stop9h 43mJetBlue
Deal found 10/29$931
This JetBlue deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:05 amSDQ - BUF
1 stop7h 46mJetBlue
Sun 11/307:54 pmBUF - SDQ
1 stop7h 27mJetBlue
Deal found 10/28$933
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/221:24 amSDQ - BUF
2 stops17h 13mMultiple Airlines
Sun 12/281:37 pmBUF - SDQ
1 stop20h 43mMultiple Airlines
Deal found 10/29$1,025

Cheap flight deals from Santo Domingo to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$359
(American Airlines)

One-way from

$181
(JetBlue)
Provider with most accurate pricing for Santo Domingo Las Americas-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Buffalo flights.
Search Deals
From Santo Domingo Las Americas to Buffalo
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One-way flight from Santo Domingo Las Americas to Buffalo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Santo Domingo

Fly to

Buffalo

Route

Depart

Return

Price

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 11/26

6:00 am-10:49 pm

2 stops17h 49m

Buffalo

Wed 12/3

5:24 pm-12:28 pm

2 stops18h 04m

$359

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 11/26

8:04 pm-11:00 am

1 stop15h 56m

Buffalo

Wed 12/3

6:45 am-2:31 pm

1 stop6h 46m

$463

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 4/2

7:05 am-2:36 pm

1 stop7h 31m

Buffalo

Sun 4/5

11:15 am-11:42 pm

1 stop12h 27m

$512

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 11/21

6:14 pm-11:02 am

2 stops17h 48m

Buffalo

Sun 11/30

7:03 pm-12:15 pm

2 stops16h 12m

$517

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 4/2

5:20 am-6:27 pm

1 stop13h 07m

Buffalo

Sun 4/5

2:29 pm-3:31 am

1 stop13h 02m

$572

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Tue 12/23

12:35 pm-4:49 pm

2 stops29h 14m

Buffalo

Sun 12/28

1:37 pm-11:20 am

1 stop20h 43m

$606

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 11/21

6:45 am-7:19 pm

1 stop13h 34m

Buffalo

Sun 11/30

11:19 am-1:36 am

1 stop13h 17m

$661

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 4/2

5:20 pm-10:47 am

2 stops17h 27m

Buffalo

Sun 4/5

8:00 pm-10:36 am

2 stops14h 36m

$677

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Mon 12/22

4:07 am-10:35 am

1 stop7h 28m

Buffalo

Sun 12/28

1:55 pm-12:38 am

1 stop9h 43m

$931

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 11/20

4:05 am-10:51 am

1 stop7h 46m

Buffalo

Sun 11/30

7:54 pm-4:21 am

1 stop7h 27m

$933

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 20 results
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Compare providers for flights from Santo Domingo to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Buffalo in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Buffalo

What is the cheapest time of day to fly from SDQ to BUF?

Find hourly flight availability from Santo Domingo to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

One of the essential ways to save on airfare from Santo Domingo to Buffalo is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 56% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Buffalo?

    Departing from Santo Domingo to Buffalo will take you 7h 31m. The distance between Santo Domingo and Buffalo is about 1773 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Santo Domingo to Buffalo one-way?

    One-way options have recently been found by users for as low as $181 on JetBlue. Other airlines that offer cheap prices include Delta from $183 and American Airlines from $190 one-way.

  • Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Buffalo.

  • Can I find deals for business class flights from Santo Domingo to Buffalo?

    Yes. Cheapflights offers flight deals from Santo Domingo to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Alternative routes for Santo Domingo to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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