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$218+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Santo Domingo to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$490
(Kiwi.com)

One-way from

$218
(JetBlue)
From Santo Domingo Las Americas to Buffalo
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One-way flight from Santo Domingo Las Americas to Buffalo
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Find flight deals from Santo Domingo to Buffalo

Cheapest flights from Santo Domingo to Buffalo
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:05 pmSDQ - BUF
2 stops25h 41mMultiple Airlines
Mon 9/296:59 pmBUF - SDQ
1 stop17h 16mMultiple Airlines
Deal found 9/9$490
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/132:35 pmSDQ - BUF
2 stops20h 54mAmerican Airlines
Sat 9/278:00 amBUF - SDQ
2 stops12h 30mAmerican Airlines
Deal found 9/11$523
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:00 amSDQ - BUF
2 stops16h 55mAmerican Airlines
Tue 9/168:00 amBUF - SDQ
2 stops12h 30mAmerican Airlines
Deal found 9/9$524
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/132:12 pmSDQ - BUF
1 stop27h 15mMultiple Airlines
Thu 9/187:41 pmBUF - SDQ
2 stops20h 19mMultiple Airlines
Deal found 9/10$622
This SmartFares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/248:10 amSDQ - BUF
1 stop6h 47mJetBlue
Mon 9/296:10 pmBUF - SDQ
1 stop14h 54mJetBlue
Deal found 9/9$623
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/133:03 pmSDQ - BUF
1 stop7h 04mJetBlue
Sat 9/276:00 amBUF - SDQ
1 stop7h 24mJetBlue
Deal found 9/10$683
This SmartFares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/132:34 pmSDQ - BUF
1 stop7h 46mJetBlue
Thu 9/189:38 amBUF - SDQ
1 stop12h 26mJetBlue
Deal found 9/10$685
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:50 pmSDQ - BUF
1 stop8h 47mDelta
Tue 9/166:00 amBUF - SDQ
1 stop7h 24mDelta
Deal found 9/9$700
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:00 amSDQ - BUF
2 stops16h 55mAmerican Airlines
Mon 9/295:38 amBUF - SDQ
2 stops14h 52mAmerican Airlines
Deal found 9/9$701
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/121:10 pmSDQ - BUF
2 stops34h 49mUnited Airlines
Tue 9/166:30 amBUF - SDQ
1 stop7h 40mUnited Airlines
Deal found 9/9$736
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/131:10 pmSDQ - BUF
2 stops10h 49mUnited Airlines
Sat 9/276:30 amBUF - SDQ
1 stop7h 32mUnited Airlines
Deal found 9/10$869

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Santo Domingo

Fly to

Buffalo

Route

Depart

Return

Price

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 9/24

5:05 pm-6:46 pm

2 stops25h 41m

Buffalo

Mon 9/29

6:59 pm-12:15 pm

1 stop17h 16m

$490

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 9/24

8:10 am-2:57 pm

1 stop6h 47m

Buffalo

Mon 9/29

6:10 pm-9:04 am

1 stop14h 54m

$623

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 9/24

7:00 am-11:55 pm

2 stops16h 55m

Buffalo

Mon 9/29

5:38 am-8:30 pm

2 stops14h 52m

$701

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Mon 3/2

2:35 am-11:50 am

1 stop10h 15m

$218

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sat 9/27

2:12 pm-4:02 pm

2 stops25h 50m

$228

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 9/26

5:05 pm-4:02 pm

3 stops46h 57m

$232

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sat 9/27

2:34 pm-10:20 pm

1 stop7h 46m

$234

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Mon 9/22

6:03 am-3:08 pm

1 stop9h 05m

$262

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Mon 9/29

6:05 pm-10:07 pm

1 stop28h 02m

$268

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 9/26

5:19 pm-9:07 pm

1 stop27h 48m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results
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Best time to book a flight from Santo Domingo to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Buffalo

What is the cheapest time of day to fly from SDQ to BUF?

Find hourly flight availability from Santo Domingo to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santo Domingo to Buffalo as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Buffalo?

    Departing from Santo Domingo to Buffalo will take you 6h 47m. The distance between Santo Domingo and Buffalo is about 1773 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Buffalo.

  • Can I find deals for business class flights from Santo Domingo to Buffalo?

    Yes. Cheapflights offers flight deals from Santo Domingo to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Buffalo (average of $256). Flying from Santo Domingo to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Alternative routes for Santo Domingo to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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