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$136+ Cheap flights from Santa Ana, CA to Buffalo (SNA - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — BUF
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Santa Ana to Buffalo

Cheapest flights from Santa Ana to Buffalo
Explore the most affordable flight options available from Santa Ana to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:45 am
SNA
-
BUF
1 stop6h 44m
American Airlines
Wed 4/157:00 am
BUF
-
SNA
1 stop9h 47m
American Airlines
Deal found 1/28$437
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:00 am
SNA
-
BUF
2 stops12h 46m
Delta
Wed 4/153:54 pm
BUF
-
SNA
2 stops9h 00m
Delta
Deal found 1/28$448
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:25 am
SNA
-
BUF
1 stop8h 25m
Southwest
Mon 4/205:15 am
BUF
-
SNA
1 stop8h 15m
Southwest
Deal found 1/28$457
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:25 am
SNA
-
BUF
1 stop8h 25m
Southwest
Sun 4/196:05 am
BUF
-
SNA
1 stop7h 25m
Southwest
Deal found 1/27$497
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:20 pm
SNA
-
BUF
2 stops17h 03m
Delta
Sat 7/46:00 am
BUF
-
SNA
1 stop7h 55m
Delta
Deal found 1/26$505

Find flight deals from Santa Ana to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$437
(American Airlines)

One-way from

$136
(eDestinos)

Popular in

December

Cheapest in

March

Average price

$456
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Buffalo flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Buffalo
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Buffalo
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Ana to Buffalo that are best for you.

Fly from

Santa Ana

Fly to

Buffalo

Route

Depart

Return

Price

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

7:45 am-5:29 pm

1 stop6h 44m

Buffalo

Wed 4/15

7:00 am-1:47 pm

1 stop9h 47m

$437

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

8:00 am-11:46 pm

2 stops12h 46m

Buffalo

Wed 4/15

3:54 pm-9:54 pm

2 stops9h 00m

$448

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

11:25 am-10:50 pm

1 stop8h 25m

Buffalo

Sat 4/25

6:30 am-12:35 pm

1 stop9h 05m

$457

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 4/15

11:25 am-10:50 pm

1 stop8h 25m

Buffalo

Mon 4/20

5:15 am-10:30 am

1 stop8h 15m

$457

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 4/15

11:25 am-10:50 pm

1 stop8h 25m

Buffalo

Sun 4/19

6:05 am-10:30 am

1 stop7h 25m

$497

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 6/29

9:20 pm-5:23 pm

2 stops17h 03m

Buffalo

Fri 7/3

4:30 pm-10:18 pm

1 stop8h 48m

$505

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 6/29

9:20 pm-5:23 pm

2 stops17h 03m

Buffalo

Thu 7/2

6:00 am-10:55 am

1 stop7h 55m

$505

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

8:58 am-11:05 am

2 stops47h 07m

$136

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 4/15

4:37 pm-8:47 am

3 stops37h 10m

$199

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 2/23

9:20 pm-10:39 pm

2 stops22h 19m

$208

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 16 results
1
2

Compare providers for flights from Santa Ana to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Buffalo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana, California-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Buffalo

What is the cheapest month to book a flight from Santa Ana, California to Buffalo?

Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Buffalo (average of $147). Flying from Santa Ana, California to Buffalo in March is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Santa Ana to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Buffalo?

    Airlines like American Airlines, Delta, and Southwest fly from Santa Ana, California to Buffalo in about 6h 44m. The time it takes to get you to your destination can typically vary by up to 6h 02m. Santa Ana, California and Buffalo are separated by a distance of 2193 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santa Ana, California to Buffalo round-trip?

    Currently priced at $276, Southwest will fly you from Santa Ana, California to Buffalo and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $357. Southwest is 46% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santa Ana, California to Buffalo one-way?

    $138 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and Southwest, with prices starting from $160 and $195, respectively.

  • Can I find deals for flights from Santa Ana to Buffalo that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Buffalo.

  • Can I find deals for business class flights from Santa Ana to Buffalo?

    Yes. Cheapflights offers flight deals from Santa Ana to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Buffalo?

    Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Buffalo (average of $147). Flying from Santa Ana, California to Buffalo in March is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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Top 2 airlines flying from Santa Ana to Buffalo

Discover the top 2 airlines that operate flights from Santa Ana to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$276Average$579FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$357Average$536FlexibilityNo cancel feeOn-time71%

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