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$178+ Cheap flights from Santa Ana, CA to Buffalo (SNA - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — BUF
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Santa Ana to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$437
(Southwest)

One-way from

$178
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$552
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Buffalo flights.
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From Santa Ana J. Wayne/Orange Cnty to Buffalo
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One-way flight from Santa Ana J. Wayne/Orange Cnty to Buffalo
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Highest demand for flights based on searches. 12% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Santa Ana to Buffalo

Cheapest flights from Santa Ana to Buffalo
Explore the most affordable flight options available from Santa Ana to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:40 amSNA - BUF
1 stop8h 50mSouthwest
Wed 12/242:05 pmBUF - SNA
1 stop9h 30mSouthwest
Deal found 10/29$410
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:00 amSNA - BUF
1 stop8h 40mSouthwest
Tue 12/163:00 pmBUF - SNA
1 stop9h 15mSouthwest
Deal found 10/28$437
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/211:42 amSNA - BUF
1 stop8h 54mAmerican Airlines
Sat 12/64:46 pmBUF - SNA
1 stop9h 13mAmerican Airlines
Deal found 10/27$447
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:20 pmSNA - BUF
2 stops14h 44mDelta
Sat 12/66:12 amBUF - SNA
1 stop7h 23mDelta
Deal found 10/27$452
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:42 pmSNA - BUF
1 stop6h 47mAmerican Airlines
Wed 12/246:00 amBUF - SNA
1 stop11h 14mAmerican Airlines
Deal found 10/27$469
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:45 amSNA - BUF
1 stop7h 42mAmerican Airlines
Mon 12/84:46 pmBUF - SNA
1 stop7h 55mAmerican Airlines
Deal found 10/27$482

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Santa Ana to Buffalo that are best for you.

Fly from

Santa Ana

Fly to

Buffalo

Route

Depart

Return

Price

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 12/18

11:40 am-11:30 pm

1 stop8h 50m

Buffalo

Wed 12/24

2:05 pm-8:35 pm

1 stop9h 30m

$410

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 12/10

11:00 am-10:40 pm

1 stop8h 40m

Buffalo

Tue 12/16

3:00 pm-9:15 pm

1 stop9h 15m

$437

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 12/2

11:42 am-11:36 pm

1 stop8h 54m

Buffalo

Sat 12/6

4:46 pm-10:59 pm

1 stop9h 13m

$447

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 12/2

5:20 pm-11:04 am

2 stops14h 44m

Buffalo

Sat 12/6

6:12 am-10:35 am

1 stop7h 23m

$452

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

9:20 pm-10:58 pm

2 stops22h 38m

Buffalo

Thu 4/2

6:25 am-10:51 am

1 stop7h 26m

$470

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

9:20 pm-10:58 pm

2 stops22h 38m

Buffalo

Wed 4/1

7:00 am-6:15 pm

2 stops14h 15m

$474

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

9:20 pm-10:58 pm

2 stops22h 38m

Buffalo

Fri 4/3

12:09 pm-6:50 pm

1 stop9h 41m

$480

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

9:20 pm-5:26 pm

2 stops17h 06m

Buffalo

Sun 4/5

6:25 am-1:11 pm

2 stops9h 46m

$485

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 3/3

12:15 pm-11:07 pm

1 stop7h 52m

Buffalo

Wed 3/4

6:00 am-11:34 am

1 stop8h 34m

$498

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 12/3

12:45 pm-9:47 am

2 stops18h 02m

$193

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 16 results
1
2

Compare providers for flights from Santa Ana to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Buffalo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana, California-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Buffalo

What is the cheapest month to book a flight from Santa Ana, California to Buffalo?

Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Buffalo (average of $147). Flying from Santa Ana, California to Buffalo in January is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated October 29, 2025.
Peruse reviews from past customers who have flown with Southwest, United Airlines, and American Airlines from Santa Ana to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,999 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Buffalo?

    Airlines like Southwest, American Airlines, and Delta fly from Santa Ana, California to Buffalo in about 8h 50m. The time it takes to get you to your destination can typically vary by up to 5h 54m. Santa Ana, California and Buffalo are separated by a distance of 2193 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santa Ana, California to Buffalo round-trip?

    Currently priced at $276, Southwest will fly you from Santa Ana, California to Buffalo and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $357 and $357, respectively. Southwest is 46% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santa Ana, California to Buffalo one-way?

    $193 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $203 and $219, respectively.

  • Can I find deals for flights from Santa Ana to Buffalo that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Buffalo.

  • Can I find deals for business class flights from Santa Ana to Buffalo?

    Yes. Cheapflights offers flight deals from Santa Ana to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Buffalo?

    Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Buffalo (average of $147). Flying from Santa Ana, California to Buffalo in January is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top 3 airlines flying from Santa Ana to Buffalo

Discover the top 3 airlines that operate flights from Santa Ana to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$276Average$579FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$357Average$536FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$357Average$510FlexibilityNo cancel feeOn-time69%

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