$355+ Cheap flights from Panama to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BUF
Nov 3 — Nov 101
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Buffalo
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Best
Last-minute
One-way
Cheapest flights from Panama to BuffaloExplore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:30 pm -
2 stops16h 38m
Mon 10/127:59 pm -
2 stops23h 38m
Deal found 10/1![United Airlines logo]()
$783
This Ovago deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2811:55 pm -
1 stop23h 14m
Tue 1/127:00 am -
1 stop13h 02m
Deal found 9/30![Copa Airlines logo]()
$825
This Avianca deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:30 am -
2 stops13h 28m
Tue 1/122:44 pm -
2 stops11h 26m
Deal found 9/30![Multiple Airlines logo]()
$865
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/288:00 am -
2 stops16h 02m
Tue 1/126:00 am -
1 stop7h 55m
Deal found 9/30![Delta logo]()
$883
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:33 pm -
2 stops18h 23m
Mon 12/217:47 pm -
2 stops19h 46m
Deal found 10/1![American Airlines logo]()
$906
This KAYAK deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:45 am -
1 stop12h 26m
Mon 10/126:30 am -
1 stop14h 01m
Deal found 10/1![Copa Airlines logo]()
$938
This Ovago deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:25 am -
3 stops19h 35m
Mon 10/127:53 pm -
2 stops15h 37m
Deal found 10/1![Multiple Airlines logo]()
$1,001
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:41 pm -
1 stop9h 02m
Sun 12/277:47 pm -
2 stops17h 54m
Deal found 10/2![American Airlines logo]()
$1,036
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:00 am -
1 stop13h 09m
Mon 12/215:35 pm -
2 stops23h 37m
Deal found 10/1![United Airlines logo]()
$1,070
Best flights from Panama to BuffaloDiscover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
Discover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2210:00 am -
1 stop13h 01m
Tue 1/268:42 pm -
1 stop23h 20m
Deal found 9/30![United Airlines logo]()
$658
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/288:00 am -
2 stops16h 02m
Tue 1/126:00 am -
1 stop7h 55m
Deal found 9/30![Delta logo]()
$883
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:41 pm -
2 stops25h 51m
Sun 12/277:47 pm -
2 stops17h 54m
Deal found 10/2![American Airlines logo]()
$1,036
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/124:41 pm -
2 stops24h 06m
Fri 2/265:50 pm -
2 stops26h 12m
Deal found 10/2![United Airlines logo]()
$690
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:00 am -
1 stop15h 55m
Sun 12/2712:20 pm -
1 stop9h 25m
Deal found 10/2![Delta logo]()
$1,102
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:00 am -
1 stop13h 09m
Mon 12/215:35 pm -
2 stops23h 37m
Deal found 10/1![United Airlines logo]()
$1,070
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 am -
1 stop12h 26m
Sat 10/246:30 am -
1 stop14h 01m
Deal found 9/30![United Airlines logo]()
$2,047
Last-minute flights from Panama to BuffaloDiscover last-minute flight deals from Panama to Buffalo. Data last updated October 4, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Buffalo. Data last updated October 4, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:30 pm -
2 stops16h 38m
Mon 10/127:59 pm -
2 stops23h 38m
Deal found 10/1![United Airlines logo]()
$783
This KAYAK deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:45 am -
1 stop12h 26m
Mon 10/126:30 am -
1 stop14h 01m
Deal found 10/1![Copa Airlines logo]()
$938
This Ovago deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:25 am -
3 stops19h 35m
Mon 10/127:53 pm -
2 stops15h 37m
Deal found 10/1![Multiple Airlines logo]()
$1,001
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 am -
1 stop12h 26m
Sat 10/246:30 am -
1 stop14h 01m
Deal found 9/29![United Airlines logo]()
$2,047
One-way flights from Panama to BuffaloSearch for one-way flight options from Panama to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
Search for one-way flight options from Panama to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/194:41 pm -
2 stops24h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$355
This Ovago deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:00 am -
1 stop9h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Copa Airlines logo]()
$494
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/194:00 pm -
3 stops28h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Multiple Airlines logo]()
$554
Find flight deals from Panama to Buffalo
Keep the following information in mind while searching for Panama to Buffalo flight deals. Data was last updated October 4, 2026.
Round-trip from | $658 (United Airlines) |
|---|---|
One-way from | $346 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
Use the filters below to find and compare flights from Panama to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 1/19
4:41 pm-4:51 pm
2 stops24h 10m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$355
Quickest round-trip
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 1/19
10:00 am-7:32 pm
1 stop9h 32m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$494
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 1/19
4:00 pm-8:43 pm
3 stops28h 43m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$554
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 1/22
10:00 am-11:01 pm
1 stop13h 01m
Buffalo
Tue 1/26
8:42 pm-8:02 pm
1 stop23h 20m
$658
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 2/12
4:41 pm-4:47 pm
2 stops24h 06m
Buffalo
Fri 2/26
5:50 pm-8:02 pm
2 stops26h 12m
$690
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Mon 12/28
8:00 am-12:02 am
2 stops16h 02m
Buffalo
Tue 1/12
6:00 am-1:55 pm
1 stop7h 55m
$883
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Thu 12/24
2:41 pm-4:32 pm
2 stops25h 51m
Buffalo
Sun 12/27
7:47 pm-1:41 pm
2 stops17h 54m
$1,036
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 12/18
10:00 am-11:09 pm
1 stop13h 09m
Buffalo
Mon 12/21
5:35 pm-5:12 pm
2 stops23h 37m
$1,070
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Thu 12/24
8:00 am-11:55 pm
1 stop15h 55m
Buffalo
Sun 12/27
12:20 pm-9:45 pm
1 stop9h 25m
$1,102
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 10/23
9:45 am-11:11 pm
1 stop12h 26m
Buffalo
Sat 10/24
6:30 am-7:31 pm
1 stop14h 01m
$2,047
Sorted by cheapest first
Best time to book a flight from Panama to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.
PTY-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Buffalo
PA0-BUF
PTY-BUF
No data available for this route at this time. Please check back soon.
Related info for your journey
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Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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