$356+ Cheap flights from Panama to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BUF
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Buffalo
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Cheapest flights from Panama to BuffaloExplore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
1 stop12h 26m
Thu 10/296:30 am -
2 stops13h 08m
Deal found 9/6![United Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:45 am -
2 stops23h 09m
Sun 11/86:00 am -
1 stop14h 02m
Deal found 9/4![United Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:02 pm -
2 stops20h 21m
Sun 11/86:21 pm -
2 stops19h 52m
Deal found 9/4![American Airlines logo]()
$682
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:45 am -
1 stop23h 10m
Sat 10/3110:51 am -
1 stop9h 11m
Deal found 9/6![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
2 stops20h 41m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 am -
1 stop12h 26m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$723
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:23 pm -
1 stop8h 29m
Tue 9/296:05 am -
1 stop7h 53m
Deal found 9/3![Delta logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops24h 13m
Mon 10/57:42 pm -
1 stop24h 49m
Deal found 9/5![United Airlines logo]()
$754
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:16 pm -
2 stops21h 02m
Mon 9/215:58 pm -
2 stops19h 28m
Deal found 9/6![American Airlines logo]()
$773
Best flights from Panama to BuffaloDiscover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
1 stop12h 26m
Thu 10/296:30 am -
2 stops13h 08m
Deal found 9/6![United Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:23 pm -
1 stop8h 29m
Tue 9/296:05 am -
1 stop7h 53m
Deal found 9/3![Delta logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
1 stop12h 26m
Sat 10/3110:51 am -
2 stops28h 54m
Deal found 9/6![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:45 am -
1 stop23h 10m
Sat 10/3110:51 am -
1 stop9h 11m
Deal found 9/6![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:45 am -
2 stops13h 05m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
2 stops20h 41m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:30 pm -
2 stops16h 38m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops24h 13m
Mon 10/57:42 pm -
1 stop24h 49m
Deal found 9/5![United Airlines logo]()
$754
Last-minute flights from Panama to BuffaloDiscover last-minute flight deals from Panama to Buffalo. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Buffalo. Data last updated September 7, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:23 pm -
1 stop8h 29m
Tue 9/296:05 am -
1 stop7h 53m
Deal found 9/3![Delta logo]()
$746
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:16 pm -
2 stops21h 02m
Mon 9/215:58 pm -
2 stops19h 28m
Deal found 9/6![American Airlines logo]()
$773
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops24h 13m
Mon 10/57:42 pm -
1 stop24h 49m
Deal found 9/5![United Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:45 am -
1 stop23h 10m
Sat 10/3110:51 am -
1 stop9h 11m
Deal found 9/6![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm -
2 stops24h 13m
Thu 10/296:00 am -
2 stops13h 38m
Deal found 9/6![United Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
2 stops20h 41m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 am -
1 stop12h 26m
Sat 10/316:00 am -
2 stops14h 02m
Deal found 9/6![United Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:45 am -
2 stops23h 09m
Sun 11/86:00 am -
1 stop14h 02m
Deal found 9/4![United Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:02 pm -
2 stops20h 21m
Sun 11/86:21 pm -
2 stops19h 52m
Deal found 9/4![American Airlines logo]()
$682
One-way flights from Panama to BuffaloSearch for one-way flight options from Panama to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Panama to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:02 pm -
2 stops19h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:00 am -
1 stop26h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:24 pm -
1 stop8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$406
This Orbitz deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:30 am -
3 stops19h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$456
This Travelocity deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:50 pm -
2 stops15h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$472
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:23 pm -
1 stop8h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:29 pm -
3 stops23h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$4,434
Find flight deals from Panama to Buffalo
Keep the following information in mind while searching for Panama to Buffalo flight deals. Data was last updated September 7, 2026.
Round-trip from | $659 (United Airlines) |
|---|---|
One-way from | $356 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Panama to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Thu 10/29
2:02 pm-10:48 am
2 stops19h 46m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$356
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 10/30
2:02 pm-11:17 am
2 stops20h 15m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$356
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 10/30
2:24 pm-11:59 pm
1 stop8h 35m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$406
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Fri 10/30
11:30 am-8:08 am
3 stops19h 38m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$456
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 9/15
3:50 pm-8:10 am
2 stops15h 20m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$472
Quickest round-trip
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 9/15
2:23 pm-11:52 pm
1 stop8h 29m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$546
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Wed 10/21
9:45 am-11:11 pm
1 stop12h 26m
Buffalo
Thu 10/29
6:30 am-6:38 pm
2 stops13h 08m
$659
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Wed 10/21
9:45 am-11:11 pm
1 stop12h 26m
Buffalo
Sat 10/31
10:51 am-2:45 pm
2 stops28h 54m
$691
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Mon 10/19
9:45 am-9:55 am
1 stop23h 10m
Buffalo
Sat 10/31
10:51 am-7:02 pm
1 stop9h 11m
$691
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 10/20
9:45 am-11:50 pm
2 stops13h 05m
Buffalo
Sat 10/31
6:00 am-7:02 pm
2 stops14h 02m
$691
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Panama to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.
PTY-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Buffalo
PA0-BUF
PTY-BUF
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Panama to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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