How long is the flight from Panama to Buffalo?

For as low as $535, United Airlines can have you in Buffalo from Panama in 8h 34m. Panama and Buffalo are separated by a distance of 2339 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What is the cheapest time of day to fly from PA to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Buffalo as you normally would.

What airport do you fly into for flights to Buffalo from Panama?

Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Panama to Buffalo.

Can I find deals for flights from Panama to Buffalo that include hotel bookings?

Yes. In addition to deals on Panama to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Buffalo.

Can I find deals for business class flights from Panama to Buffalo?

Yes. Cheapflights offers flight deals from Panama to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$535+ Flights from Panama to Buffalo

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Find flight deals from Panama to Buffalo

Cheapest flights from Panama to Buffalo
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 22, 2025.

Thu 12/2510:00 amPTY - BUF

1 stop8h 34mUnited Airlines

Thu 1/2911:24 amBUF - PTY

1 stop8h 38mUnited Airlines

Deal found 11/21

$535

Fri 12/264:55 pmPTY - BUF

2 stops23h 29mAmerican Airlines

Thu 1/16:29 pmBUF - PTY

2 stops19h 24mAmerican Airlines

Deal found 11/21

$558

Fri 12/268:00 amPTY - BUF

2 stops15h 28mDelta

Thu 1/16:00 amBUF - PTY

1 stop7h 57mDelta

Deal found 11/21

$661

Mon 12/294:41 pmPTY - BUF

2 stops20h 43mUnited Airlines

Sun 1/1111:24 amBUF - PTY

1 stop8h 38mUnited Airlines

Deal found 11/20

$683

Mon 12/298:00 amPTY - BUF

1 stop15h 47mDelta

Sun 1/116:00 amBUF - PTY

1 stop7h 55mDelta

Deal found 11/20

$787

Wed 12/3111:55 pmPTY - BUF

2 stops16h 39mUnited Airlines

Thu 1/17:48 pmBUF - PTY

2 stops18h 07mUnited Airlines

Deal found 11/20

$1,129

Mon 12/297:50 pmPTY - BUF

2 stops23h 16mAvianca

Sun 1/119:55 amBUF - PTY

3 stops33h 00mAvianca

Deal found 11/20

$1,229

Sun 12/282:55 amPTY - BUF

2 stops18h 13mMultiple Airlines

Sun 1/119:08 amBUF - PTY

1 stop8h 00mMultiple Airlines

Deal found 11/20

$1,242

Best flights from Panama to Buffalo
Discover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 22, 2025.

Thu 12/2510:00 amPTY - BUF

1 stop8h 34mUnited Airlines

Thu 1/292:49 pmBUF - PTY

2 stops23h 56mUnited Airlines

Deal found 11/21

$535

Tue 1/132:27 pmPTY - BUF

2 stops24h 50mAmerican Airlines

Mon 1/195:27 pmBUF - PTY

2 stops20h 00mAmerican Airlines

Deal found 11/20

$559

Tue 1/133:20 pmPTY - BUF

1 stop8h 36mDelta

Mon 1/196:00 amBUF - PTY

1 stop7h 55mDelta

Deal found 11/20

$661

Wed 2/254:41 pmPTY - BUF

2 stops20h 36mUnited Airlines

Sat 2/287:00 amBUF - PTY

2 stops13h 02mUnited Airlines

Deal found 11/19

$535

Fri 12/268:00 amPTY - BUF

2 stops15h 28mDelta

Thu 1/16:00 amBUF - PTY

1 stop7h 57mDelta

Deal found 11/21

$661

Mon 12/294:41 pmPTY - BUF

2 stops20h 43mUnited Airlines

Sun 1/1111:24 amBUF - PTY

1 stop8h 38mUnited Airlines

Deal found 11/20

$683

Tue 1/134:41 pmPTY - BUF

2 stops27h 48mUnited Airlines

Mon 1/1911:24 amBUF - PTY

1 stop8h 38mUnited Airlines

Deal found 11/20

$755

Last-minute flights from Panama to Buffalo
Discover last-minute flight deals from Panama to Buffalo. Data last updated November 22, 2025 and is based on user searches.

Thu 12/2510:00 amPTY - BUF

1 stop8h 34mUnited Airlines

Thu 1/292:49 pmBUF - PTY

2 stops23h 56mUnited Airlines

Deal found 11/21

$535

Fri 12/264:55 pmPTY - BUF

2 stops23h 29mAmerican Airlines

Thu 1/16:29 pmBUF - PTY

2 stops19h 24mAmerican Airlines

Deal found 11/21

$558

Fri 12/268:00 amPTY - BUF

2 stops15h 28mDelta

Thu 1/16:00 amBUF - PTY

1 stop7h 57mDelta

Deal found 11/21

$661

Sun 12/282:55 amPTY - BUF

2 stops18h 13mMultiple Airlines

Sun 1/119:08 amBUF - PTY

1 stop8h 00mMultiple Airlines

Deal found 11/20

$1,242

Mon 12/294:41 pmPTY - BUF

2 stops20h 43mUnited Airlines

Sun 1/1111:24 amBUF - PTY

1 stop8h 38mUnited Airlines

Deal found 11/20

$683

Mon 12/298:00 amPTY - BUF

1 stop15h 47mDelta

Sun 1/116:00 amBUF - PTY

1 stop7h 55mDelta

Deal found 11/20

$787

Mon 12/297:50 pmPTY - BUF

2 stops23h 16mAvianca

Sun 1/119:55 amBUF - PTY

3 stops33h 00mAvianca

Deal found 11/20

$1,229

Wed 12/3111:55 pmPTY - BUF

2 stops16h 39mUnited Airlines

Thu 1/17:48 pmBUF - PTY

2 stops18h 07mUnited Airlines

Deal found 11/20

$1,129

Cheap flight deals from Panama to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$535 (United Airlines)

Provider with most accurate pricing for Panama City Tocumen Intl-Buffalo flight deals.

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From Panama to Buffalo

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Fly from

Fly to

Route

Depart

Return

Price

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 12/25

10:00 am-6:34 pm

1 stop8h 34m

Buffalo

Thu 1/29

2:49 pm-2:45 pm

2 stops23h 56m

$535

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 2/25

4:41 pm-1:17 pm

2 stops20h 36m

Buffalo

Sat 2/28

7:00 am-8:02 pm

2 stops13h 02m

$535

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 1/13

2:27 pm-3:17 pm

2 stops24h 50m

Buffalo

Mon 1/19

5:27 pm-1:27 pm

2 stops20h 00m

$559

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 1/13

3:20 pm-11:56 pm

1 stop8h 36m

Buffalo

Mon 1/19

6:00 am-1:55 pm

1 stop7h 55m

$661

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 12/26

8:00 am-11:28 pm

2 stops15h 28m

Buffalo

Thu 1/1

6:00 am-1:57 pm

1 stop7h 57m

$661

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Mon 12/29

4:41 pm-1:24 pm

2 stops20h 43m

Buffalo

Sun 1/11

11:24 am-8:02 pm

1 stop8h 38m

$683

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 1/13

4:41 pm-8:29 pm

2 stops27h 48m

Buffalo

Mon 1/19

11:24 am-8:02 pm

1 stop8h 38m

$755

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/21

Best time to book a flight from Panama to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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Everything you need to know about your flight from Panama to Buffalo

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Buffalo from Panama?
Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Panama to Buffalo.
How long is the flight from Panama to Buffalo?
For as low as $535, United Airlines can have you in Buffalo from Panama in 8h 34m. Panama and Buffalo are separated by a distance of 2339 mi. Both multi-stop and nonstop flights can be found to your destination and back.
Can I find deals for flights from Panama to Buffalo that include hotel bookings?
Yes. In addition to deals on Panama to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Buffalo.
Can I find deals for business class flights from Panama to Buffalo?
Yes. Cheapflights offers flight deals from Panama to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$535+ Cheap flights from Panama to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Panama to Buffalo

Cheapest flights from Panama to BuffaloExplore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 22, 2025.

Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 22, 2025.

Cheap flight deals from Panama to Buffalo

Keep the following information in mind while searching for Panama to Buffalo flight deals. Data was last updated November 22, 2025.

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Round-trip from

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Use the filters below to find and compare flights from Panama to Buffalo that are best for you.

Best time to book a flight from Panama to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama to Buffalo

Related info for your journey

Find useful and relevant information for your journey from Panama to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Panama?

How long is the flight from Panama to Buffalo?

Can I find deals for flights from Panama to Buffalo that include hotel bookings?

How can I find direct flights from Panama to Buffalo?

Can I find deals for business class flights from Panama to Buffalo?

Traveling to a place near Buffalo?

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Cheapest flights from Panama to Buffalo
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 22, 2025.