$402+ Cheap flights from Panama to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BUF
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to BuffaloExplore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:00 am -
2 stops13h 46m
Tue 12/811:23 am -
2 stops27h 22m
Deal found 10/18![United Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:00 am -
1 stop12h 59m
Tue 11/246:00 am -
1 stop14h 02m
Deal found 10/17![United Airlines logo]()
$810
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
1 stop12h 59m
Sat 11/1410:51 am -
1 stop9h 11m
Deal found 10/19![United Airlines logo]()
$1,037
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:00 am -
1 stop10h 09m
Sat 11/146:00 am -
1 stop14h 02m
Deal found 10/18![United Airlines logo]()
$1,138
This Mytrip deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:10 pm -
3 stops26h 19m
Tue 11/249:20 pm -
3 stops28h 00m
Deal found 10/17![Multiple Airlines logo]()
$1,538
Best flights from Panama to BuffaloDiscover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:00 am -
1 stop12h 59m
Tue 12/811:23 am -
1 stop8h 39m
Deal found 10/18![United Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:00 am -
1 stop12h 59m
Tue 11/246:00 am -
1 stop14h 02m
Deal found 10/17![United Airlines logo]()
$810
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
1 stop12h 59m
Sat 11/1410:51 am -
1 stop9h 11m
Deal found 10/19![United Airlines logo]()
$1,037
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:00 am -
1 stop10h 09m
Sat 11/146:00 am -
1 stop14h 02m
Deal found 10/18![United Airlines logo]()
$1,138
Last-minute flights from Panama to BuffaloDiscover last-minute flight deals from Panama to Buffalo. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Buffalo. Data last updated October 20, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:00 am -
1 stop10h 09m
Sat 11/146:00 am -
1 stop14h 02m
Deal found 10/18![United Airlines logo]()
$1,138
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
1 stop12h 59m
Sat 11/1410:51 am -
1 stop9h 11m
Deal found 10/19![United Airlines logo]()
$1,037
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:00 am -
2 stops13h 46m
Tue 12/811:23 am -
2 stops27h 22m
Deal found 10/18![United Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:00 am -
1 stop12h 59m
Tue 11/246:00 am -
1 stop14h 02m
Deal found 10/17![United Airlines logo]()
$810
This Mytrip deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:10 pm -
3 stops26h 19m
Tue 11/249:20 pm -
3 stops28h 00m
Deal found 10/17![Multiple Airlines logo]()
$1,538
One-way flights from Panama to BuffaloSearch for one-way flight options from Panama to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Panama to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:31 pm -
2 stops15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:31 pm -
3 stops39h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:31 pm -
3 stops22h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:33 pm -
3 stops24h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$509
This Avianca deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:30 am -
2 stops12h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:24 pm -
1 stop8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Delta logo]()
$568
Find flight deals from Panama to Buffalo
Keep the following information in mind while searching for Panama to Buffalo flight deals. Data was last updated October 20, 2026.
Round-trip from | $756 (United Airlines) |
|---|---|
One-way from | $402 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Panama to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Mon 11/23
9:31 pm-8:24 pm
3 stops22h 53m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$478
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 10/27
2:24 pm-11:59 pm
1 stop8h 35m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$568
Quickest round-trip
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Thu 11/19
3:29 pm-11:59 pm
1 stop8h 30m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$572
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Wed 11/18
3:29 pm-11:59 pm
1 stop8h 30m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$572
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Mon 11/23
3:29 pm-11:59 pm
1 stop8h 30m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$572
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 10/27
2:02 pm-10:48 am
2 stops19h 46m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$577
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 11/17
10:00 am-10:59 pm
1 stop12h 59m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$579
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Sun 11/22
3:29 pm-11:59 pm
1 stop8h 30m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$606
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Sun 11/15
3:29 pm-11:59 pm
1 stop8h 30m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$611
Panama CityBuffalo
PTY Panama City Tocumen Intl - BUF Buffalo
PTYBUF
Panama City Tocumen Intl
Tue 10/27
9:31 pm-5:52 pm
3 stops43h 21m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$637
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Panama to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.
PTY-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Buffalo
PA0-BUF
PTY-BUF
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Panama to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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