How long is the flight from Panama to Buffalo?

For as low as $535, United Airlines can have you in Buffalo from Panama in 8h 34m. Panama and Buffalo are separated by a distance of 2339 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What is the cheapest time of day to fly from PA to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Buffalo as you normally would.

What airport do you fly into for flights to Buffalo from Panama?

Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Panama to Buffalo.

Can I find deals for flights from Panama to Buffalo that include hotel bookings?

Yes. In addition to deals on Panama to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Buffalo.

Can I find deals for business class flights from Panama to Buffalo?

Yes. Cheapflights offers flight deals from Panama to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$535+ Flights from Panama to Buffalo

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Panama to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Panama to Buffalo

Cheapest flights from Panama to Buffalo
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Fri 12/2610:00 amPTY - BUF

1 stop8h 34mUnited Airlines

Thu 1/16:30 amBUF - PTY

2 stops32h 15mUnited Airlines

Deal found 10/29

$535

Fri 12/264:55 pmPTY - BUF

2 stops23h 29mAmerican Airlines

Thu 1/17:15 pmBUF - PTY

2 stops20h 39mAmerican Airlines

Deal found 10/30

$548

Fri 12/268:00 amPTY - BUF

1 stop9h 47mDelta

Thu 1/16:10 amBUF - PTY

2 stops13h 50mDelta

Deal found 10/30

$661

Fri 12/2611:55 pmPTY - BUF

2 stops19h 11mMultiple Airlines

Thu 1/17:48 pmBUF - PTY

3 stops19h 07mMultiple Airlines

Deal found 10/30

$2,648

Best flights from Panama to Buffalo
Discover carefully curated flight deals from Panama to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Fri 12/2610:00 amPTY - BUF

1 stop8h 34mUnited Airlines

Thu 1/16:30 amBUF - PTY

2 stops32h 15mUnited Airlines

Deal found 10/29

$535

Fri 12/264:55 pmPTY - BUF

2 stops23h 29mAmerican Airlines

Thu 1/17:15 pmBUF - PTY

2 stops20h 39mAmerican Airlines

Deal found 10/30

$548

Fri 12/268:00 amPTY - BUF

1 stop9h 47mDelta

Thu 1/16:10 amBUF - PTY

2 stops13h 50mDelta

Deal found 10/30

$661

Tue 1/132:27 pmPTY - BUF

2 stops20h 30mAmerican Airlines

Mon 1/195:16 pmBUF - PTY

2 stops20h 11mAmerican Airlines

Deal found 10/29

$558

Tue 1/134:41 pmPTY - BUF

2 stops20h 43mUnited Airlines

Mon 1/1911:24 amBUF - PTY

1 stop8h 38mUnited Airlines

Deal found 10/29

$755

Tue 1/133:20 pmPTY - BUF

1 stop8h 38mDelta

Mon 1/196:00 amBUF - PTY

1 stop7h 55mDelta

Deal found 10/29

$787

Cheap flight deals from Panama to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$535 (United Airlines)

Provider with most accurate pricing for Panama City Tocumen Intl-Buffalo flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Buffalo flights.

Search Deals

From Panama to Buffalo

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 12/26

10:00 am-6:34 pm

1 stop8h 34m

Buffalo

Thu 1/1

6:30 am-2:45 pm

2 stops32h 15m

$535

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 12/26

4:55 pm-4:24 pm

2 stops23h 29m

Buffalo

Thu 1/1

7:15 pm-3:54 pm

2 stops20h 39m

$548

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 1/13

2:27 pm-10:57 am

2 stops20h 30m

Buffalo

Mon 1/19

5:16 pm-1:27 pm

2 stops20h 11m

$558

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 12/26

8:00 am-5:47 pm

1 stop9h 47m

Buffalo

Thu 1/1

6:10 am-8:00 pm

2 stops13h 50m

$661

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 1/13

4:41 pm-1:24 pm

2 stops20h 43m

Buffalo

Mon 1/19

11:24 am-8:02 pm

1 stop8h 38m

$755

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 1/13

3:20 pm-11:58 pm

1 stop8h 38m

Buffalo

Mon 1/19

6:00 am-1:55 pm

1 stop7h 55m

$787

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Best time to book a flight from Panama to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Buffalo

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Buffalo from Panama?
Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Panama to Buffalo.
How long is the flight from Panama to Buffalo?
For as low as $535, United Airlines can have you in Buffalo from Panama in 8h 34m. Panama and Buffalo are separated by a distance of 2339 mi. Both multi-stop and nonstop flights can be found to your destination and back.
Can I find deals for flights from Panama to Buffalo that include hotel bookings?
Yes. In addition to deals on Panama to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Buffalo.
Can I find deals for business class flights from Panama to Buffalo?
Yes. Cheapflights offers flight deals from Panama to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Lockport

Cheektowaga

Orchard Park

Batavia

Williamsville

Eden

Amherst

West Seneca

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$535+ Cheap flights from Panama to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Panama to Buffalo

Cheapest flights from Panama to BuffaloExplore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Cheap flight deals from Panama to Buffalo

Keep the following information in mind while searching for Panama to Buffalo flight deals. Data was last updated October 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama to Buffalo that are best for you.

Best time to book a flight from Panama to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama to Buffalo

Related info for your journey

Find useful and relevant information for your journey from Panama to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Panama?

How long is the flight from Panama to Buffalo?

Can I find deals for flights from Panama to Buffalo that include hotel bookings?

How can I find direct flights from Panama to Buffalo?

Can I find deals for business class flights from Panama to Buffalo?

Traveling to a place near Buffalo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Panama to Buffalo
Explore the most affordable flight options available from Panama to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.