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$646+ Cheap flights from Lyon (LYS) to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — BUF
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
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Cheap flight deals from Lyon to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Lyon (LYS) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 14, 2026.

Round-trip from

$646
(American Airlines)
From Lyon-Saint Exupéry to Buffalo
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Find flight deals from Lyon to Buffalo

Cheapest flights from Lyon to Buffalo
Explore the most affordable flight options available from Lyon to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:10 am
LYS
-
BUF
2 stops23h 30m
American Airlines
Tue 3/36:01 pm
BUF
-
LYS
2 stops18h 04m
American Airlines
Deal found 1/11$646
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:10 am
LYS
-
BUF
2 stops35h 33m
American Airlines
Mon 3/211:23 am
BUF
-
LYS
2 stops19h 52m
American Airlines
Deal found 1/13$649
This British Airways deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/299:35 am
LYS
-
BUF
2 stops19h 20m
Multiple Airlines
Mon 2/24:01 pm
BUF
-
LYS
2 stops25h 44m
Multiple Airlines
Deal found 1/13$731
This Air Canada deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/291:40 pm
LYS
-
BUF
3 stops29h 44m
Air Canada
Mon 2/28:30 am
BUF
-
LYS
3 stops20h 35m
Air Canada
Deal found 1/13$1,279
This Flighttix deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/88:10 pm
LYS
-
BUF
2 stops34h 06m
Scandinavian Airlines
Thu 2/1211:52 am
BUF
-
LYS
2 stops25h 33m
Scandinavian Airlines
Deal found 1/13$4,691
This Air Canada deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/81:40 pm
LYS
-
BUF
3 stops29h 44m
Multiple Airlines
Thu 2/125:24 pm
BUF
-
LYS
2 stops35h 41m
Multiple Airlines
Deal found 1/13$8,756

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Lyon to Buffalo that are best for you.

Fly from

Lyon

Fly to

Buffalo

Route

Depart

Return

Price

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Fri 2/27

6:10 am-11:40 pm

2 stops23h 30m

Buffalo

Tue 3/3

6:01 pm-6:05 pm

2 stops18h 04m

$646

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 2/26

6:10 am-11:43 am

2 stops35h 33m

Buffalo

Mon 3/2

11:23 am-1:15 pm

2 stops19h 52m

$649

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/29

9:35 am-10:55 pm

2 stops19h 20m

Buffalo

Mon 2/2

4:01 pm-11:45 pm

2 stops25h 44m

$731

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/29

1:40 pm-1:24 pm

3 stops29h 44m

Buffalo

Mon 2/2

8:30 am-11:05 am

3 stops20h 35m

$1,279

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Sun 2/8

8:10 pm-12:16 am

2 stops34h 06m

Buffalo

Thu 2/12

11:52 am-7:25 pm

2 stops25h 33m

$4,691

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Sun 2/8

1:40 pm-1:24 pm

3 stops29h 44m

Buffalo

Thu 2/12

5:24 pm-11:05 am

2 stops35h 41m

$8,756

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/11

Best time to book a flight from Lyon to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lyon to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lyon to Buffalo?

    Airlines like American Airlines and Air Canada fly from Lyon to Buffalo in about 23h 30m. The time it takes to get you to your destination can typically vary by up to 6h 14m. The distance from Lyon to Buffalo is about 3944 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Lyon to Buffalo that include hotel bookings?

    Yes. In addition to deals on Lyon to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to Buffalo.

  • Can I find deals for business class flights from Lyon to Buffalo?

    Yes. Cheapflights offers flight deals from Lyon to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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