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$741+ Cheap flights from Lyon (LYS) to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — BUF
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Lyon to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Lyon (LYS) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Round-trip from

$741
(American Airlines)
From Lyon-Saint Exupéry to Buffalo
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Find flight deals from Lyon to Buffalo

Cheapest flights from Lyon to Buffalo
Explore the most affordable flight options available from Lyon to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:25 amLYS - BUF
2 stops17h 26mUnited Airlines
Tue 12/95:40 pmBUF - LYS
2 stops35h 25mUnited Airlines
Deal found 11/25$971
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:25 amLYS - BUF
2 stops20h 50mUnited Airlines
Wed 12/105:40 pmBUF - LYS
2 stops18h 20mUnited Airlines
Deal found 11/25$975
This Expedia deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:10 amLYS - BUF
2 stops23h 29mIberia
Thu 12/112:50 pmBUF - LYS
2 stops15h 05mIberia
Deal found 11/24$1,004
This KAYAK deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:10 pmLYS - BUF
2 stops40h 29mBritish Airways
Tue 12/93:34 pmBUF - LYS
2 stops17h 36mBritish Airways
Deal found 11/25$1,020
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:55 amLYS - BUF
2 stops30h 51mUnited Airlines
Thu 1/16:30 amBUF - LYS
2 stops29h 50mUnited Airlines
Deal found 11/25$1,026
This KAYAK deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:05 pmLYS - BUF
2 stops39h 34mBritish Airways
Sat 12/64:46 pmBUF - LYS
2 stops21h 04mBritish Airways
Deal found 11/25$1,079
This KAYAK deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:35 amLYS - BUF
2 stops20h 04mBritish Airways
Thu 12/113:32 pmBUF - LYS
2 stops22h 48mBritish Airways
Deal found 11/24$1,080
This KAYAK deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 pmLYS - BUF
2 stops52h 59mBritish Airways
Thu 1/13:58 pmBUF - LYS
2 stops14h 27mBritish Airways
Deal found 11/25$1,472
This Air Canada deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:55 pmLYS - BUF
3 stops29h 17mMultiple Airlines
Thu 12/115:40 pmBUF - LYS
2 stops35h 25mMultiple Airlines
Deal found 11/24$1,578
This Air Canada deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:55 amLYS - BUF
3 stops34h 29mMultiple Airlines
Thu 1/17:48 pmBUF - LYS
2 stops33h 17mMultiple Airlines
Deal found 11/25$1,641
This Expedia deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:00 amLYS - BUF
2 stops28h 20mTAP AIR PORTUGAL
Wed 12/105:00 pmBUF - LYS
2 stops18h 35mTAP AIR PORTUGAL
Deal found 11/25$1,690

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Lyon to Buffalo that are best for you.

Fly from

Lyon

Fly to

Buffalo

Route

Depart

Return

Price

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 3/5

6:10 am-10:58 pm

2 stops22h 48m

Buffalo

Mon 3/9

4:25 pm-1:15 pm

2 stops15h 50m

$741

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/8

2:10 pm-12:16 am

2 stops16h 06m

Buffalo

Thu 1/15

11:51 am-2:05 pm

2 stops20h 14m

$824

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 12/24

8:55 am-9:46 am

2 stops30h 51m

Buffalo

Thu 1/1

6:30 am-6:20 pm

2 stops29h 50m

$1,026

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 12/24

7:00 pm-5:59 pm

2 stops52h 59m

Buffalo

Thu 1/1

3:58 pm-12:25 pm

2 stops14h 27m

$1,472

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/8

1:40 pm-1:24 pm

3 stops29h 44m

Buffalo

Thu 1/15

6:20 pm-11:05 am

2 stops34h 45m

$1,567

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 12/24

8:55 am-1:24 pm

3 stops34h 29m

Buffalo

Thu 1/1

7:48 pm-11:05 am

2 stops33h 17m

$1,641

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/8

1:40 pm-1:24 pm

3 stops29h 44m

Buffalo

Thu 1/15

5:23 pm-11:05 am

3 stops35h 42m

$1,741

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Best time to book a flight from Lyon to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lyon to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lyon to Buffalo?

    Airlines like American Airlines, Delta, and United Airlines fly from Lyon to Buffalo in about 16h 06m. The time it takes to get you to your destination can typically vary by up to 14h 45m. The distance from Lyon to Buffalo is about 3944 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Lyon to Buffalo that include hotel bookings?

    Yes. In addition to deals on Lyon to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to Buffalo.

  • Can I find deals for business class flights from Lyon to Buffalo?

    Yes. Cheapflights offers flight deals from Lyon to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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