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$741+ Cheap flights from Lyon (LYS) to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — BUF
Dec 21 — Dec 281
Sun 12/21
Sun 12/28
1 adult, Economy
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Cheap flight deals from Lyon to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Lyon (LYS) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 21, 2025.

Round-trip from

$744
(American Airlines)
From Lyon-Saint Exupéry to Buffalo
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Find flight deals from Lyon to Buffalo

Cheapest flights from Lyon to Buffalo
Explore the most affordable flight options available from Lyon to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2025.

This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:10 amLYS - BUF
2 stops23h 57mAmerican Airlines
Mon 12/85:05 amBUF - LYS
2 stops26h 10mAmerican Airlines
Deal found 11/18$844
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:20 amLYS - BUF
2 stops20h 55mUnited Airlines
Wed 12/106:00 amBUF - LYS
2 stops23h 05mUnited Airlines
Deal found 11/20$913
This Air Canada deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:55 pmLYS - BUF
2 stops26h 52mMultiple Airlines
Wed 12/107:00 amBUF - LYS
3 stops22h 05mMultiple Airlines
Deal found 11/20$1,938
This Air Canada deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:55 pmLYS - BUF
3 stops29h 17mAir Canada
Wed 12/107:00 amBUF - LYS
3 stops22h 05mAir Canada
Deal found 11/20$6,011

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Lyon to Buffalo that are best for you.

Fly from

Lyon

Fly to

Buffalo

Route

Depart

Return

Price

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 3/5

9:35 am-11:20 pm

2 stops19h 45m

Buffalo

Mon 3/9

11:15 am-1:15 pm

2 stops21h 00m

$741

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 12/4

6:10 am-12:07 am

2 stops23h 57m

Buffalo

Mon 12/8

5:05 am-1:15 pm

2 stops26h 10m

$844

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Sat 12/6

6:20 am-9:15 pm

2 stops20h 55m

Buffalo

Wed 12/10

6:00 am-11:05 am

2 stops23h 05m

$913

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Sat 1/3

7:00 am-9:46 am

2 stops32h 46m

Buffalo

Sat 1/10

11:24 am-11:05 am

2 stops17h 41m

$1,678

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Sat 12/6

1:55 pm-10:47 am

2 stops26h 52m

Buffalo

Wed 12/10

7:00 am-11:05 am

3 stops22h 05m

$1,938

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Best time to book a flight from Lyon to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lyon to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lyon to Buffalo?

    Airlines like American Airlines and United Airlines fly from Lyon to Buffalo in about 20h 55m. The time it takes to get you to your destination can typically vary by up to 1h 52m. The distance from Lyon to Buffalo is about 3944 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Lyon to Buffalo that include hotel bookings?

    Yes. In addition to deals on Lyon to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to Buffalo.

  • Can I find deals for business class flights from Lyon to Buffalo?

    Yes. Cheapflights offers flight deals from Lyon to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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