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$655+ Cheap flights from Lyon (LYS) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — BUF
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Lyon to Buffalo

Best flights from Lyon to Buffalo
Discover carefully curated flight deals from Lyon to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:10 amLYS - BUF
2 stops23h 06mAmerican Airlines
Tue 3/35:30 amBUF - LYS
2 stops24h 50mAmerican Airlines
Deal found 12/20$776
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 amLYS - BUF
2 stops33h 17mUnited Airlines
Sat 4/187:45 pmBUF - LYS
2 stops34h 35mUnited Airlines
Deal found 12/22$856
This Kissandfly.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/76:50 pmLYS - BUF
2 stops33h 41mLufthansa
Sun 1/112:49 pmBUF - LYS
2 stops38h 16mLufthansa
Deal found 12/22$1,085
This Air Canada deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:35 pmLYS - BUF
3 stops25h 37mMultiple Airlines
Sun 4/1910:50 amBUF - LYS
2 stops18h 50mMultiple Airlines
Deal found 12/22$2,129
This Air Canada deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:25 pmLYS - BUF
3 stops29h 48mMultiple Airlines
Sat 4/1810:35 amBUF - LYS
2 stops43h 05mMultiple Airlines
Deal found 12/22$2,786
This Air Canada deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:35 pmLYS - BUF
3 stops25h 37mAir Canada
Sun 4/1910:50 amBUF - LYS
3 stops18h 50mAir Canada
Deal found 12/22$6,041
This Air Canada deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:45 amLYS - BUF
3 stops19h 58mMultiple Airlines
Fri 4/1710:55 amBUF - LYS
2 stops18h 45mMultiple Airlines
Deal found 12/22$3,412
This Air Canada deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:20 pmLYS - BUF
3 stops25h 52mAir Canada
Fri 4/1710:55 amBUF - LYS
3 stops18h 45mAir Canada
Deal found 12/22$6,594

Find flight deals from Lyon to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Lyon (LYS) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2025.

Round-trip from

$776
(American Airlines)

One-way from

$655
(Justfly.com)
From Lyon-Saint Exupéry to Buffalo
Search Deals
One-way flight from Lyon-Saint Exupéry to Buffalo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Lyon to Buffalo that are best for you.

Fly from

Lyon

Fly to

Buffalo

Route

Depart

Return

Price

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Fri 2/27

6:10 am-11:16 pm

2 stops23h 06m

Buffalo

Tue 3/3

5:30 am-12:20 pm

2 stops24h 50m

$776

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Tue 4/7

6:55 am-10:12 am

2 stops33h 17m

Buffalo

Sat 4/18

7:45 pm-12:20 pm

2 stops34h 35m

$856

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 1/7

6:50 pm-10:31 pm

2 stops33h 41m

Buffalo

Sun 1/11

2:49 pm-11:05 am

2 stops38h 16m

$1,085

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 4/8

2:35 pm-10:12 am

3 stops25h 37m

Buffalo

Sun 4/19

10:50 am-11:40 am

2 stops18h 50m

$2,129

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Tue 4/7

1:25 pm-1:13 pm

3 stops29h 48m

Buffalo

Sat 4/18

10:35 am-11:40 am

2 stops43h 05m

$2,786

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Mon 4/6

6:45 am-8:43 pm

3 stops19h 58m

Buffalo

Fri 4/17

10:55 am-11:40 am

2 stops18h 45m

$3,412

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 4/8

2:35 pm-10:12 am

3 stops25h 37m

Buffalo

Sun 4/19

10:50 am-11:40 am

3 stops18h 50m

$6,041

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Mon 4/6

2:20 pm-10:12 am

3 stops25h 52m

Buffalo

Fri 4/17

10:55 am-11:40 am

3 stops18h 45m

$6,594

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Wed 3/18

6:10 am-11:31 pm

2 stops22h 21m

$655

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/23

Best time to book a flight from Lyon to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lyon to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lyon to Buffalo?

    Airlines like American Airlines, United Airlines, and Lufthansa fly from Lyon to Buffalo in about 23h 06m. The time it takes to get you to your destination can typically vary by up to 10h 35m. The distance from Lyon to Buffalo is about 3944 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Lyon to Buffalo that include hotel bookings?

    Yes. In addition to deals on Lyon to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to Buffalo.

  • Can I find deals for business class flights from Lyon to Buffalo?

    Yes. Cheapflights offers flight deals from Lyon to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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