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$649+ Cheap flights from Lyon (LYS) to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — BUF
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheap flight deals from Lyon to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Lyon (LYS) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 6, 2026.

Round-trip from

$649
(American Airlines)
From Lyon-Saint Exupéry to Buffalo
Search Deals

Find flight deals from Lyon to Buffalo

Cheapest flights from Lyon to Buffalo
Explore the most affordable flight options available from Lyon to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:10 amLYS - BUF
2 stops23h 30mAmerican Airlines
Tue 3/34:25 pmBUF - LYS
2 stops16h 45mAmerican Airlines
Deal found 1/5$649
This Iberia deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:10 amLYS - BUF
2 stops23h 38mMultiple Airlines
Mon 1/2611:22 amBUF - LYS
2 stops24h 08mMultiple Airlines
Deal found 1/6$651
This Flighttix deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:10 amLYS - BUF
2 stops23h 38mIberia
Mon 1/2611:22 amBUF - LYS
2 stops18h 33mIberia
Deal found 1/6$700
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/61:40 pmLYS - BUF
2 stops30h 34mUnited Airlines
Tue 1/131:59 pmBUF - LYS
2 stops16h 26mUnited Airlines
Deal found 1/5$4,772
This Air Canada deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/221:40 pmLYS - BUF
3 stops29h 44mAir Canada
Mon 1/268:30 amBUF - LYS
3 stops20h 35mAir Canada
Deal found 1/6$5,952

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Lyon to Buffalo that are best for you.

Fly from

Lyon

Fly to

Buffalo

Route

Depart

Return

Price

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Fri 2/27

6:10 am-11:40 pm

2 stops23h 30m

Buffalo

Tue 3/3

4:25 pm-3:10 pm

2 stops16h 45m

$649

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/22

6:10 am-11:48 pm

2 stops23h 38m

Buffalo

Mon 1/26

11:22 am-5:30 pm

2 stops24h 08m

$651

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/22

6:10 am-11:48 pm

2 stops23h 38m

Buffalo

Mon 1/26

11:22 am-11:55 am

2 stops18h 33m

$700

LyonBuffalo

LYS - BUF

LYSBUF

Lyon-Saint Exupéry

Thu 1/22

1:40 pm-1:24 pm

3 stops29h 44m

Buffalo

Mon 1/26

8:30 am-11:05 am

3 stops20h 35m

$5,952

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Best time to book a flight from Lyon to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lyon to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lyon to Buffalo?

    Airlines like American Airlines and Iberia fly from Lyon to Buffalo in about 23h 30m. The time it takes to get you to your destination can typically vary by up to 08m. The distance from Lyon to Buffalo is about 3944 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Lyon to Buffalo that include hotel bookings?

    Yes. In addition to deals on Lyon to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to Buffalo.

  • Can I find deals for business class flights from Lyon to Buffalo?

    Yes. Cheapflights offers flight deals from Lyon to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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