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$432+ Cheap flights from La Crosse to Buffalo (LSE - BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — BUF
Oct 31 — Nov 71
Fri 10/31
Fri 11/7
1 adult, Economy
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Cheap flight deals from La Crosse to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 1, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$432
(American Airlines)
Provider with most accurate pricing for La Crosse-Buffalo flight deals.
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Provider most trusted by Cheapflights users for La Crosse-Buffalo flights.
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From La Crosse to Buffalo
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Find flight deals from La Crosse to Buffalo

Cheapest flights from La Crosse to Buffalo
Explore the most affordable flight options available from La Crosse to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2025.

This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:15 pmLSE - BUF
1 stop4h 20mAmerican Airlines
Sat 10/186:14 amBUF - LSE
1 stop5h 10mAmerican Airlines
Deal found 9/29$432

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 1, 2025.
Use the filters below to find and compare flights from La Crosse to Buffalo that are best for you.

Fly from

La Crosse

Fly to

Buffalo

Route

Depart

Return

Price

La CrosseBuffalo

LSE - BUF

LSEBUF

La Crosse

Wed 10/15

6:15 pm-11:35 pm

1 stop4h 20m

Buffalo

Sat 10/18

6:14 am-10:24 am

1 stop5h 10m

$432

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/29

Compare providers for flights from La Crosse to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to Buffalo in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on La Crosse-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on La Crosse-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from La Crosse-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on La Crosse-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from La Crosse to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to Buffalo?

    A quick flight from La Crosse to Buffalo can take about 4h 20m. American Airlines provides one of the quickest options available for as low as $432. Airlines will cover a distance of 631 mi.

  • Can I find deals for flights from La Crosse to Buffalo that include hotel bookings?

    Yes. In addition to deals on La Crosse to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Buffalo.

  • Can I find deals for business class flights from La Crosse to Buffalo?

    Yes. Cheapflights offers flight deals from La Crosse to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from La Crosse to Buffalo (average of $256). Flying from La Crosse to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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