$472+ Cheap flights from La Crosse to Buffalo (LSE - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — BUF
Dec 20 — Dec 271
1 adult, Economy
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1. Tell us where you want to go
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Best flights from La Crosse to BuffaloDiscover carefully curated flight deals from La Crosse to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2025.
Discover carefully curated flight deals from La Crosse to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2025.
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:08 pmLSE - BUF
1 stop5h 40mAmerican Airlines
Sat 1/315:17 pmBUF - LSE
1 stop5h 59mAmerican Airlines
Deal found 11/18![American Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1611:37 amLSE - BUF
1 stop3h 58mAmerican Airlines
Mon 1/197:30 amBUF - LSE
1 stop4h 37mAmerican Airlines
Deal found 11/19![American Airlines logo]()
$478
Cheap flight deals from La Crosse to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $472 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from La Crosse to Buffalo that are best for you.
Fly from
La Crosse
Fly to
Buffalo
Route
Depart
Return
Price
La CrosseBuffalo
LSE - BUF
LSEBUF
La Crosse
Tue 1/27
5:08 pm-11:48 pm
1 stop5h 40m
Buffalo
Sat 1/31
5:17 pm-10:16 pm
1 stop5h 59m
$472
La CrosseBuffalo
LSE - BUF
LSEBUF
La Crosse
Fri 1/16
11:37 am-4:35 pm
1 stop3h 58m
Buffalo
Mon 1/19
7:30 am-11:07 am
1 stop4h 37m
$478
Compare providers for flights from La Crosse to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to Buffalo in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on La Crosse-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on La Crosse-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from La Crosse-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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