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$116+ Cheap flights from Key West to Buffalo (EYW - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/21. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Key West to Buffalo

Cheapest flights from Key West to Buffalo
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2812:34 pmEYW - BUF
1 stop6h 01mAmerican Airlines
Tue 12/26:00 amBUF - EYW
1 stop8h 08mAmerican Airlines
Deal found 11/13$431

Cheap flight deals from Key West to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$276
(Delta)

One-way from

$116
(Kiwi.com)
Provider with most accurate pricing for Key West-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Key West-Buffalo flights.
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From Key West to Buffalo
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One-way flight from Key West to Buffalo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.

Fly from

Key West

Fly to

Buffalo

Route

Depart

Return

Price

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/19

6:07 pm-11:29 pm

1 stop5h 22m

Buffalo

Mon 2/23

12:14 pm-7:42 pm

1 stop7h 28m

$276

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/19

6:07 pm-11:29 pm

1 stop5h 22m

Buffalo

Tue 2/24

10:31 am-7:42 pm

2 stops9h 11m

$281

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Fri 2/20

7:10 am-5:01 pm

2 stops9h 51m

Buffalo

Tue 2/24

12:14 pm-7:42 pm

1 stop7h 28m

$389

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sun 12/21

8:55 am-4:45 pm

2 stops31h 50m

$116

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 3/12

9:46 am-10:42 am

1 stop24h 56m

$178

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Tue 2/24

5:13 pm-11:35 pm

1 stop6h 22m

$249

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Tue 2/24

7:10 am-5:01 pm

2 stops9h 51m

$254

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 3/12

1:59 pm-10:46 pm

2 stops8h 47m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

  • Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated November 13, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,009 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Buffalo?

    Delta can get you from Key West to Buffalo in just under 5h 22m. Your travel time can differ by up to . Key West and Buffalo are separated by a distance of 1281 mi.

  • What are the cheapest airlines flying from Key West to Buffalo round-trip?

    Flying on Delta is currently your cheapest option to Buffalo, with prices starting at $259. Another option worth looking into is American Airlines, starting at $268 round trip.

  • Can I find deals for flights from Key West to Buffalo that include hotel bookings?

    Yes. In addition to deals on Key West to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Buffalo.

  • Can I find deals for business class flights from Key West to Buffalo?

    Yes. Cheapflights offers flight deals from Key West to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top 2 airlines flying from Key West to Buffalo

Discover the top 2 airlines that operate flights from Key West to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$268Average$383FlexibilityNo cancel feeOn-time71%

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