$173+ Cheap flights from Key West to Buffalo (EYW - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Dec 3 — Dec 101
1 adult, Economy
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Best flights from Key West to BuffaloDiscover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2025.
Discover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2025.
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:00 amEYW - BUF
2 stops10h 26mDelta
Mon 2/236:00 amBUF - EYW
1 stop5h 03mDelta
Deal found 10/31![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:58 pmEYW - BUF
1 stop4h 55mAmerican Airlines
Mon 2/235:20 amBUF - EYW
1 stop6h 03mAmerican Airlines
Deal found 11/1![American Airlines logo]()
$476
Cheap flight deals from Key West to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 3, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 1 star |
Round-trip from | $319 (Delta) |
One-way from | $173 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Key West to Buffalo that are best for you.
Fly from
Key West
Fly to
Buffalo
Route
Depart
Return
Price
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 2/19
7:00 am-5:26 pm
2 stops10h 26m
Buffalo
Mon 2/23
6:00 am-11:03 am
1 stop5h 03m
$319
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Thu 2/19
1:58 pm-6:53 pm
1 stop4h 55m
Buffalo
Mon 2/23
5:20 am-11:23 am
1 stop6h 03m
$476
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Wed 11/12
10:47 am-1:37 pm
2 stops26h 50m
$173
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 1/5
6:08 pm-11:58 pm
1 stop5h 50m
$295
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sun 1/4
6:20 pm-11:47 pm
1 stop5h 27m
$540
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Sun 1/4
8:09 pm-3:24 pm
2 stops19h 15m
$590
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 11/10
6:33 pm-11:26 pm
1 stop4h 53m
$779
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 11/10
12:45 pm-10:00 pm
1 stop9h 15m
$883
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 11/10
4:00 pm-10:58 pm
2 stops30h 58m
$1,155
Key WestBuffalo
EYW - BUF
EYWBUF
Key West
Mon 11/10
7:40 am-5:00 pm
2 stops9h 20m
$1,206
- Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated November 3, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.2
Food
7.3
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.9
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Boarding
8.2
Food
7.3
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.9
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Boarding
8.2
Food
7.3
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.9
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Related info for your journey
Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca
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Alternative routes for Key West to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Key West to Buffalo
Discover the top 2 airlines that operate flights from Key West to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$318 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$383 | FlexibilityNo cancel fee | On-time71% |