How long is the flight from Key West to Buffalo?

American Airlines and United Airlines can get you from Key West to Buffalo in just under 5h 06m. Your travel time can differ by up to 03m. Key West and Buffalo are separated by a distance of 1281 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Key West to Buffalo round-trip?

Flying on Delta is currently your cheapest option to Buffalo, with prices starting at $259. Another option worth looking into is American Airlines, starting at $268 round trip.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What is the cheapest time of day to fly from EYW to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key West to Buffalo as you normally would.

Most accurate provider : When it comes to deals on Key West-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Key West-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Key West to Buffalo that include hotel bookings?

Yes. In addition to deals on Key West to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Key West to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Buffalo.

Can I find deals for business class flights from Key West to Buffalo?

Yes. Cheapflights offers flight deals from Key West to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$258+ Flights from Key West to Buffalo

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1. Tell us where you want to go

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2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheap flight deals from Key West to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$286 (American Airlines)
One-way from	$258 (Kiwi.com)

Provider with most accurate pricing for Key West-Buffalo flight deals.

Search Deals

Provider most trusted by Cheapflights users for Key West-Buffalo flights.

Search Deals

From Key West to Buffalo

Search Deals

One-way flight from Key West to Buffalo

Search Deals

Find flight deals from Key West to Buffalo

Cheapest flights from Key West to Buffalo
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

Thu 2/127:45 amEYW - BUF

1 stop5h 06mAmerican Airlines

Wed 2/185:24 amBUF - EYW

1 stop6h 08mAmerican Airlines

Deal found 1/6

$286

Thu 2/126:35 pmEYW - BUF

1 stop5h 09mUnited Airlines

Wed 2/186:07 amBUF - EYW

2 stops11h 47mUnited Airlines

Deal found 1/6

$291

Thu 1/222:25 pmEYW - BUF

1 stop8h 06mUnited Airlines

Sun 1/259:55 amBUF - EYW

1 stop6h 27mUnited Airlines

Deal found 1/6

$419

Best flights from Key West to Buffalo
Discover carefully curated flight deals from Key West to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 7, 2026.

Thu 2/127:45 amEYW - BUF

1 stop5h 06mAmerican Airlines

Wed 2/185:24 amBUF - EYW

1 stop6h 08mAmerican Airlines

Deal found 1/6

$286

Thu 2/126:35 pmEYW - BUF

1 stop5h 09mUnited Airlines

Wed 2/186:07 amBUF - EYW

2 stops11h 47mUnited Airlines

Deal found 1/6

$291

Thu 1/222:25 pmEYW - BUF

1 stop8h 06mUnited Airlines

Sun 1/259:55 amBUF - EYW

1 stop6h 27mUnited Airlines

Deal found 1/5

$419

Last-minute flights from Key West to Buffalo
Discover last-minute flight deals from Key West to Buffalo. Data last updated January 7, 2026 and is based on user searches.

Thu 1/222:25 pmEYW - BUF

1 stop8h 06mUnited Airlines

Sun 1/259:55 amBUF - EYW

1 stop6h 27mUnited Airlines

Deal found 1/6

$419

Thu 2/127:45 amEYW - BUF

1 stop5h 06mAmerican Airlines

Wed 2/185:24 amBUF - EYW

1 stop6h 08mAmerican Airlines

Deal found 1/6

$286

Thu 2/126:35 pmEYW - BUF

1 stop5h 09mUnited Airlines

Wed 2/186:07 amBUF - EYW

2 stops11h 47mUnited Airlines

Deal found 1/6

$291

One-way flights from Key West to Buffalo
Search for one-way flight options from Key West to Buffalo. Find affordable one-way fares based on user searches. Data last updated January 7, 2026.

Sun 3/2210:27 pmEYW - BUF

2 stops13h 38mMultiple Airlines

Deal found 1/6

$258

Wed 5/271:02 pmEYW - BUF

1 stop5h 36mAmerican Airlines

Deal found 1/7

$305

Wed 5/272:35 pmEYW - BUF

2 stops8h 28mDelta

Deal found 1/7

$310

Mon 3/231:06 pmEYW - BUF

1 stop7h 24mMultiple Airlines

Deal found 1/6

$311

Sat 3/213:32 pmEYW - BUF

2 stops20h 33mMultiple Airlines

Deal found 1/6

$313

Mon 3/233:56 pmEYW - BUF

2 stops7h 54mAmerican Airlines

Deal found 1/6

$393

Sun 3/227:45 amEYW - BUF

1 stop5h 06mAmerican Airlines

Deal found 1/7

$438

Fly from

Fly to

Route

Depart

Return

Price

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/12

7:45 am-12:51 pm

1 stop5h 06m

Buffalo

Wed 2/18

5:24 am-11:32 am

1 stop6h 08m

$286

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 2/12

6:35 pm-11:44 pm

1 stop5h 09m

Buffalo

Wed 2/18

6:07 am-5:54 pm

2 stops11h 47m

$291

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 1/22

2:25 pm-10:31 pm

1 stop8h 06m

Buffalo

Sun 1/25

9:55 am-4:22 pm

1 stop6h 27m

$419

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sun 3/22

10:27 pm-12:05 pm

2 stops13h 38m

$258

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Wed 5/27

1:02 pm-6:38 pm

1 stop5h 36m

$305

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Wed 5/27

2:35 pm-11:03 pm

2 stops8h 28m

$310

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Mon 3/23

1:06 pm-8:30 pm

1 stop7h 24m

$311

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sat 3/21

3:32 pm-12:05 pm

2 stops20h 33m

$313

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sun 3/22

7:45 am-12:51 pm

1 stop5h 06m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Compare providers for flights from Key West to Buffalo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Buffalo in January.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Key West-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Key West-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Key West-Buffalo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Key West-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Read reviews from past customers who have flown Delta and American Airlines from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,025 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Delta

7.9

Good

8,025 reviews

Delta

7.9

Good

8,025 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

American Airlines

7.2

Good

11,095 reviews

Delta

7.9

Good

8,025 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

How long is the flight from Key West to Buffalo?
American Airlines and United Airlines can get you from Key West to Buffalo in just under 5h 06m. Your travel time can differ by up to 03m. Key West and Buffalo are separated by a distance of 1281 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Key West to Buffalo round-trip?
Flying on Delta is currently your cheapest option to Buffalo, with prices starting at $259. Another option worth looking into is American Airlines, starting at $268 round trip.
Can I find deals for flights from Key West to Buffalo that include hotel bookings?
Yes. In addition to deals on Key West to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key West to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Buffalo.
Can I find deals for business class flights from Key West to Buffalo?
Yes. Cheapflights offers flight deals from Key West to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Key West to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$259	Average$318	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$268	Average$415	FlexibilityNo cancel fee	On-time71%

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$258+ Cheap flights from Key West to Buffalo (EYW - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Key West to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Key West to Buffalo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Key West to Buffalo

Cheapest flights from Key West to BuffaloExplore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key West to Buffalo that are best for you.

Compare providers for flights from Key West to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Buffalo in January.

Best time to book a flight from Key West to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Key West with our price prediction graph.

Reviews of airlines servicing Buffalo

Read reviews from past customers who have flown Delta and American Airlines from Key West to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Key West to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Key West to Buffalo?

What are the cheapest airlines flying from Key West to Buffalo round-trip?

Can I find deals for flights from Key West to Buffalo that include hotel bookings?

How can I find direct flights from Key West to Buffalo?

Can I find deals for business class flights from Key West to Buffalo?

Traveling to a place near Buffalo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key West to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Key West to Buffalo

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Book with Flexibility

Travel Smart

Cheapest flights from Key West to Buffalo
Explore the most affordable flight options available from Key West to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.