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$72+ Cheap flights from Florida Keys to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Florida Keys to Buffalo

Keep the following information in mind while searching for Florida Keys to Buffalo flight deals. Data was last updated September 16, 2025.

Round-trip from

$144
(Priceline)

One-way from

$72
(Frontier)

Popular in

February

Cheapest in

October

Average price

$418
From Florida Keys to Buffalo
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One-way flight from Florida Keys to Buffalo
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Highest demand for flights based on searches. 30% potential increase in price ($189 potential increase over avg. RT price).
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Cheapest flight prices on average. 15% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Florida Keys to Buffalo

Cheapest flights from Florida Keys to Buffalo
Explore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:30 amMIA - BUF
1 stop5h 52mFrontier
Thu 9/2512:17 pmBUF - MIA
1 stop11h 55mFrontier
Deal found 9/15$144
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:00 amMIA - BUF
1 stop10h 03mFrontier
Fri 9/2612:17 pmBUF - MIA
1 stop11h 55mFrontier
Deal found 9/13$145
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:05 pmMIA - BUF
1 stop4h 45mSouthwest
Mon 10/204:15 pmBUF - MIA
1 stop6h 20mSouthwest
Deal found 9/14$159
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:05 pmMIA - BUF
1 stop4h 45mSouthwest
Sun 10/198:00 amBUF - MIA
1 stop10h 00mSouthwest
Deal found 9/15$164
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:55 amMIA - BUF
2 stops9h 25mSouthwest
Tue 11/1112:40 pmBUF - MIA
2 stops9h 10mSouthwest
Deal found 9/15$169
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:30 amMIA - BUF
1 stop5h 52mFrontier
Thu 9/2512:17 pmBUF - MIA
1 stop11h 55mFrontier
Deal found 9/14$171
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:00 amMIA - BUF
1 stop10h 02mFrontier
Mon 9/2212:17 pmBUF - MIA
1 stop11h 55mFrontier
Deal found 9/14$182
This Justfly.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:30 amMIA - BUF
1 stop5h 52mFrontier
Fri 9/2612:17 pmBUF - MIA
1 stop11h 55mFrontier
Deal found 9/15$193
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:15 amMIA - BUF
1 stop6h 04mFrontier
Mon 10/275:24 pmBUF - MIA
2 stops20h 04mFrontier
Deal found 9/15$194
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/135:15 amMIA - BUF
1 stop6h 04mFrontier
Sat 10/181:02 pmBUF - MIA
1 stop10h 21mFrontier
Deal found 9/15$198
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:10 pmMIA - BUF
1 stop4h 50mSouthwest
Sun 1/42:45 pmBUF - MIA
2 stops8h 15mSouthwest
Deal found 9/14$204
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:30 amMIA - BUF
1 stop5h 52mFrontier
Mon 9/2912:17 pmBUF - MIA
1 stop11h 55mFrontier
Deal found 9/14$209

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Florida Keys to Buffalo that are best for you.

Fly from

Florida Keys

Fly to

Buffalo

Route

Depart

Return

Price

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fri 10/17

6:00 am-4:29 pm

1 stop10h 29m

Buffalo

Fri 10/24

5:24 pm-6:19 am

1 stop12h 55m

$145

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 10/16

7:05 pm-11:50 pm

1 stop4h 45m

Buffalo

Mon 10/20

4:15 pm-10:35 pm

1 stop6h 20m

$159

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fri 11/7

6:20 am-12:00 pm

1 stop5h 40m

Buffalo

Sun 11/9

3:40 pm-11:25 pm

1 stop7h 45m

$159

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 10/23

5:15 pm-10:15 pm

1 stop5h 00m

Buffalo

Mon 10/27

3:10 pm-10:50 pm

1 stop7h 40m

$159

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Tue 10/28

6:55 am-12:00 pm

1 stop5h 05m

Buffalo

Wed 10/29

5:10 pm-9:55 pm

1 stop4h 45m

$159

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 11/6

6:55 am-4:20 pm

2 stops9h 25m

Buffalo

Tue 11/11

12:40 pm-9:50 pm

2 stops9h 10m

$169

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 11/6

5:01 am-3:28 pm

1 stop10h 27m

Buffalo

Sun 11/9

2:42 pm-12:34 am

1 stop9h 52m

$182

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Wed 2/25

4:40 pm-11:57 pm

1 stop7h 17m

Buffalo

Tue 3/3

2:30 pm-11:00 pm

1 stop8h 30m

$217

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 10/16

5:25 pm-10:52 pm

1 stop5h 27m

Buffalo

Mon 10/20

4:35 pm-12:29 am

1 stop7h 54m

$217

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 2/26

5:59 pm-11:49 pm

1 stop5h 50m

Buffalo

Wed 3/4

6:50 pm-12:57 am

1 stop6h 07m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 34 results
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Best time to book a flight from Florida Keys to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Buffalo
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 16, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Florida Keys to Buffalo have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,957 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
JetBlue
7.2
Good
2,914 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Florida Keys?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Buffalo.

  • How long is the flight from Florida Keys to Buffalo?

    Frontier, Southwest, and Delta can get you from Florida Keys to Buffalo in just under 4h 45m. Your travel time can differ by up to 5h 44m. Airlines will cover a distance of 1187 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Florida Keys to Buffalo that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Buffalo.

  • Can I find deals for business class flights from Florida Keys to Buffalo?

    Yes. Cheapflights offers flight deals from Florida Keys to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Florida Keys to Buffalo (average of $256). Flying from Florida Keys to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top 2 airlines flying from Florida Keys to Buffalo

Discover the top 2 airlines that operate flights from Florida Keys to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$408FlexibilityNo cancel feeOn-time71%
DeltaCheapest$259Average$323FlexibilityNo cancel feeOn-timeN/A

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