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$64+ Cheap flights from Florida Keys to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
Jan 19 — Jan 261
Mo 1/19
Mo 1/26
1 adult, Economy
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Cheap flight deals from Florida Keys to Buffalo

Cheapest flights from Florida Keys to Buffalo
Explore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Dezember 20, 2025.

This Southwest deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/311:05 pmMIA - BUF
1 stop7h 35mSouthwest
Mi 1/73:45 pmBUF - MIA
1 stop5h 15mSouthwest
Deal found 12/17$189
This Southwest deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/311:05 pmMIA - BUF
1 stop7h 35mSouthwest
Fr 1/91:20 pmBUF - MIA
1 stop6h 45mSouthwest
Deal found 12/18$193
This Southwest deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 12/307:05 pmMIA - BUF
1 stop5h 00mSouthwest
Fr 1/91:20 pmBUF - MIA
1 stop6h 45mSouthwest
Deal found 12/18$212
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/244:01 pmMIA - BUF
1 stop7h 36mDelta
Sa 1/36:54 pmBUF - MIA
1 stop5h 52mDelta
Deal found 12/19$217
This Southwest deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/246:55 amMIA - BUF
2 stops7h 25mSouthwest
Sa 1/38:30 amBUF - MIA
1 stop10h 30mSouthwest
Deal found 12/19$228
This Expedia deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 12/295:30 amMIA - BUF
1 stop11h 15mFrontier
Fr 1/25:40 pmBUF - MIA
1 stop7h 07mFrontier
Deal found 12/19$233
This Southwest deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 12/286:30 amMIA - BUF
1 stop5h 30mSouthwest
Sa 1/38:30 amBUF - MIA
1 stop10h 30mSouthwest
Deal found 12/19$246
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 12/205:07 pmMIA - BUF
1 stop6h 40mDelta
Mo 12/226:54 pmBUF - MIA
1 stop5h 54mDelta
Deal found 12/17$258
This Southwest deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 12/296:00 amMIA - BUF
1 stop8h 05mSouthwest
So 1/412:40 pmBUF - MIA
1 stop10h 20mSouthwest
Deal found 12/18$262
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/243:09 pmEYW - BUF
1 stop8h 24mUnited Airlines
Do 1/16:30 amBUF - EYW
1 stop8h 42mUnited Airlines
Deal found 12/19$346
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/241:02 pmEYW - BUF
2 stops9h 31mDelta
Do 1/16:00 amBUF - EYW
1 stop6h 07mDelta
Deal found 12/19$351
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 12/2411:47 amEYW - BUF
2 stops6h 44mAmerican Airlines
Do 1/16:00 amBUF - EYW
1 stop7h 47mAmerican Airlines
Deal found 12/19$468

Find flight deals from Florida Keys to Buffalo

Keep the following information in mind while searching for Florida Keys to Buffalo flight deals. Data was last updated Dezember 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$166
(Kiwi.com)

One-way from

$64
(Frontier)
Provider with most accurate pricing for Key West-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Buffalo flights.
Search Deals
From Florida Keys to Buffalo
Search Deals
One-way flight from Florida Keys to Buffalo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Dezember 20, 2025.
Use the filters below to find and compare flights from Florida Keys to Buffalo that are best for you.

Fly from

Florida Keys

Fly to

Buffalo

Route

Depart

Return

Price

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Sa 1/31

7:00 am-12:00 pm

1 stop5h 00m

Buffalo

Mo 2/2

1:20 pm-8:05 pm

1 stop6h 45m

$176

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Mi 12/31

6:55 am-2:20 pm

2 stops7h 25m

Buffalo

Fr 1/9

1:20 pm-8:05 pm

1 stop6h 45m

$198

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fr 1/16

7:09 pm-7:11 pm

2 stops24h 02m

Buffalo

Mo 1/19

11:44 am-12:42 am

1 stop12h 58m

$207

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Mi 1/7

6:55 am-11:40 am

1 stop4h 45m

Buffalo

Fr 1/9

1:20 pm-8:05 pm

1 stop6h 45m

$212

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Di 2/24

7:55 am-3:10 pm

1 stop7h 15m

Buffalo

Fr 2/27

1:25 pm-11:35 pm

1 stop10h 10m

$213

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Di 12/30

5:01 pm-11:47 pm

1 stop6h 46m

Buffalo

Fr 1/9

6:38 pm-12:51 am

1 stop6h 13m

$217

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fr 5/8

6:00 am-11:02 am

1 stop5h 02m

Buffalo

Mo 5/11

4:57 pm-12:56 am

1 stop7h 59m

$217

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Sa 1/31

5:30 am-10:07 am

2 stops28h 37m

Buffalo

Mo 2/2

1:39 pm-5:54 pm

2 stops28h 15m

$235

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Sa 1/31

8:39 pm-11:59 pm

Nonstop3h 20m

Buffalo

Mo 2/2

12:38 pm-9:02 pm

1 stop8h 24m

$242

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Mi 1/7

11:00 am-5:40 pm

1 stop6h 40m

Buffalo

Fr 1/9

8:30 am-9:54 pm

2 stops13h 24m

$246

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 29 results
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Best time to book a flight from Florida Keys to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Buffalo
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated Dezember 20, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Florida Keys to Buffalo have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,258 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,018 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
JetBlue
7.2
Good
2,896 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.8
Fair
3,083 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Florida Keys?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Buffalo.

  • How long is the flight from Florida Keys to Buffalo?

    Southwest, Delta, and United Airlines can get you from Florida Keys to Buffalo in just under 5h. Your travel time can differ by up to 3h 06m. Airlines will cover a distance of 1187 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Florida Keys to Buffalo one-way?

    The cheapest airline one-way is JetBlue, with whom users have recently found tickets for as low as $68. However, be on the lookout for offers from Frontier and Southwest, as they are both options that can get you from Florida Keys to Buffalo for a low price.

  • Can I find deals for flights from Florida Keys to Buffalo that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Buffalo.

  • Can I find deals for business class flights from Florida Keys to Buffalo?

    Yes. Cheapflights offers flight deals from Florida Keys to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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Alternative routes for Florida Keys to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Florida Keys to Buffalo

Discover the top 2 airlines that operate flights from Florida Keys to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Dezember 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$268Average$415FlexibilityNo cancel feeOn-time71%

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