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$84+ Cheap flights from Florida Keys to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BUF
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Florida Keys to Buffalo

Keep the following information in mind while searching for Florida Keys to Buffalo flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$167
(American Airlines)

One-way from

$84
(American Airlines)

Popular in

February

Cheapest in

October

Average price

$259
Provider with most accurate pricing for Key West-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Key West-Buffalo flights.
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From Florida Keys to Buffalo
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One-way flight from Florida Keys to Buffalo
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Highest demand for flights based on searches. 29% potential increase in price ($179 potential increase over avg. RT price).
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Cheapest flight prices on average. 14% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Florida Keys to Buffalo

Cheapest flights from Florida Keys to Buffalo
Explore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/298:30 amMIA - BUF
1 stop6h 36mAmerican Airlines
Thu 6/57:53 pmBUF - MIA
1 stop4h 36mAmerican Airlines
Deal found 5/1$167
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/212:30 pmMIA - BUF
1 stop7h 24mJetBlue
Sat 5/243:05 pmBUF - MIA
1 stop9h 08mJetBlue
Deal found 4/29$211
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/203:19 pmMIA - BUF
1 stop7h 54mDelta
Tue 5/276:30 amBUF - MIA
1 stop5h 22mDelta
Deal found 4/29$217
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1512:20 pmMIA - BUF
2 stops11h 16mUnited Airlines
Mon 5/196:00 amBUF - MIA
1 stop5h 11mUnited Airlines
Deal found 4/30$232
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/248:54 amMIA - BUF
1 stop5h 33mFrontier
Sun 5/253:54 pmBUF - MIA
1 stop6h 13mFrontier
Deal found 4/29$261
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/66:25 amMIA - BUF
1 stop8h 30mSouthwest
Mon 6/95:35 amBUF - MIA
2 stops10h 10mSouthwest
Deal found 5/1$262
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:25 pmEYW - BUF
1 stop5h 28mDelta
Tue 5/206:00 amBUF - EYW
1 stop4h 51mDelta
Deal found 4/30$319
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/141:39 pmEYW - BUF
2 stops10h 14mAmerican Airlines
Tue 5/206:01 amBUF - EYW
2 stops6h 50mAmerican Airlines
Deal found 4/30$329
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2912:38 pmMIA - BUF
1 stop22h 12mMultiple Airlines
Sun 7/611:41 amBUF - MIA
3 stops31h 04mMultiple Airlines
Deal found 4/29$505
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/168:45 amEYW - BUF
3 stops10h 06mUnited Airlines
Tue 5/206:00 amBUF - EYW
2 stops12h 05mUnited Airlines
Deal found 5/1$738

Cheapflights Fare Finder

Customize your flight search to find flights from Florida Keys to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Florida Keys to Buffalo that are best for you.

Fly from

Florida Keys

Fly to

Buffalo

Route

Depart

Return

Price

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 5/29

8:30 am-3:06 pm

1 stop6h 36m

Buffalo

Thu 6/5

7:53 pm-12:29 am

1 stop4h 36m

$167

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Wed 5/21

2:30 pm-9:54 pm

1 stop7h 24m

Buffalo

Sat 5/24

3:05 pm-12:13 am

1 stop9h 08m

$211

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Tue 5/20

3:59 pm-11:55 pm

1 stop7h 56m

Buffalo

Mon 5/26

6:30 am-11:52 am

1 stop5h 22m

$217

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Thu 5/15

12:20 pm-9:22 pm

1 stop9h 02m

Buffalo

Sun 5/18

6:45 am-2:56 pm

1 stop8h 11m

$227

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Sat 5/24

8:54 am-2:27 pm

1 stop5h 33m

Buffalo

Sun 5/25

3:54 pm-10:07 pm

1 stop6h 13m

$261

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fri 6/6

6:25 am-2:55 pm

1 stop8h 30m

Buffalo

Mon 6/9

5:35 am-3:45 pm

2 stops10h 10m

$262

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Wed 5/14

6:25 pm-11:53 pm

1 stop5h 28m

Buffalo

Tue 5/20

6:00 am-10:51 am

1 stop4h 51m

$319

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Wed 5/14

1:39 pm-11:53 pm

2 stops10h 14m

Buffalo

Tue 5/20

6:01 am-12:51 pm

2 stops6h 50m

$329

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Sun 6/29

12:38 pm-10:50 am

1 stop22h 12m

Buffalo

Sun 7/6

11:41 am-6:45 pm

3 stops31h 04m

$505

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Fri 5/16

8:45 am-6:51 pm

3 stops10h 06m

Buffalo

Tue 5/20

6:00 am-6:05 pm

2 stops12h 05m

$738

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Florida Keys to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Buffalo

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated May 1, 2025.
To help decide which airline to fly from Florida Keys to Buffalo, see what other customers have to say about Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Entertainment

7.1

Boarding

8.1

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,972 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Entertainment

7.1

Boarding

8.1

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,293 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Entertainment

7.1

Boarding

8.1

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,934 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Entertainment

7.1

Boarding

8.1

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Entertainment

7.1

Boarding

8.1

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
JetBlue
7.3
Good
2,923 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Entertainment

7.1

Boarding

8.1

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Florida Keys?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Buffalo.

  • What are the cheapest airlines to fly from Florida Keys to Buffalo one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $84. However, be on the lookout for offers from JetBlue and Delta, as they are both options that can get you from Florida Keys to Buffalo for a low price.

  • Can I find deals for flights from Florida Keys to Buffalo that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Buffalo.

  • Can I find deals for business class flights from Florida Keys to Buffalo?

    Yes. Cheapflights offers flight deals from Florida Keys to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Florida Keys to Buffalo (average of $256). Flying from Florida Keys to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florida Keys?

Book flights to Florida Keys if you plan to visit one of these locations
Williamsville
Amherst
West Seneca
Batavia
Orchard Park
Cheektowaga

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Florida Keys to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Florida Keys to Buffalo

Discover the top 2 airlines that operate flights from Florida Keys to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$359FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$287Average$418FlexibilityNo cancel feeOn-time71%

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