What are the cheapest airlines to fly from Florida Keys to Buffalo one-way?

The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $79. However, be on the lookout for offers from American Airlines and Frontier, as they are both options that can get you from Florida Keys to Buffalo for a low price.

What is the cheapest month to book a flight from Florida Keys to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Florida Keys to Buffalo (average of $256). Flying from Florida Keys to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

How far in advance should I book a flight from Florida Keys to Buffalo?

Find a great deal and save up to 62% by booking at least 30 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Florida Keys to Buffalo within the next two weeks, with the cheapest ticket starting at $236.

What is the cheapest month to fly from Florida Keys to Buffalo?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, February can be a great choice for travel to Buffalo. Flights to Buffalo from Florida Keys in February are about $272 on average during February, but can be found for as low as $149.

What is the cheapest time of day to fly from EOA to BUF?

When flying from Florida Keys to Buffalo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Buffalo from Florida Keys?

Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Buffalo.

Can I find deals for flights from Florida Keys to Buffalo that include hotel bookings?

Yes. In addition to deals on Florida Keys to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florida Keys to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Buffalo.

Can I find deals for business class flights from Florida Keys to Buffalo?

Yes. Cheapflights offers flight deals from Florida Keys to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$79+ Flights from Florida Keys to Buffalo

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Cheap flight deals from Florida Keys to Buffalo

Round-trip from	$158 (Southwest)
One-way from	$79 (Southwest)

From Florida Keys to Buffalo

Search Deals

One-way flight from Florida Keys to Buffalo

Search Deals

Find flight deals from Florida Keys to Buffalo

Cheapest flights from Florida Keys to Buffalo
Explore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Tue 7/2212:00 pmMIA - BUF

1 stop6h 40mSouthwest

Sat 7/265:25 pmBUF - MIA

1 stop4h 55mSouthwest

Deal found 7/1

$158

Fri 7/258:43 amMIA - BUF

1 stop6h 50mAmerican Airlines

Fri 8/16:28 amBUF - MIA

1 stop4h 30mAmerican Airlines

Deal found 6/30

$159

Wed 8/66:00 amMIA - BUF

1 stop10h 17mFrontier

Sun 8/109:51 amBUF - MIA

1 stop7h 42mFrontier

Deal found 6/30

$184

Wed 7/2310:33 amMIA - BUF

1 stop8h 07mDelta

Wed 7/306:00 amBUF - MIA

1 stop4h 52mDelta

Deal found 6/30

$217

Thu 7/312:20 pmMIA - BUF

2 stops11h 18mUnited Airlines

Sat 7/56:00 amBUF - MIA

1 stop8h 11mUnited Airlines

Deal found 7/1

$232

Mon 8/256:20 pmEYW - BUF

1 stop5h 37mDelta

Wed 9/312:02 pmBUF - EYW

1 stop5h 10mDelta

Deal found 7/2

$269

Thu 9/43:45 pmEYW - BUF

1 stop6h 08mAmerican Airlines

Mon 9/88:00 amBUF - EYW

1 stop6h 00mAmerican Airlines

Deal found 7/2

$294

Sun 12/211:00 pmEYW - BUF

1 stop5h 21mUnited Airlines

Tue 1/66:00 amBUF - EYW

1 stop6h 46mUnited Airlines

Deal found 6/30

$409

Best flights from Florida Keys to Buffalo
Discover carefully curated flight deals from Florida Keys to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Tue 7/2212:00 pmMIA - BUF

1 stop6h 40mSouthwest

Sat 7/265:25 pmBUF - MIA

1 stop4h 55mSouthwest

Deal found 7/1

$158

Fri 7/258:43 amMIA - BUF

1 stop6h 50mAmerican Airlines

Fri 8/16:28 amBUF - MIA

1 stop4h 30mAmerican Airlines

Deal found 6/30

$159

Wed 8/66:00 amMIA - BUF

1 stop10h 17mFrontier

Sun 8/109:51 amBUF - MIA

1 stop7h 42mFrontier

Deal found 6/30

$184

Wed 7/2310:33 amMIA - BUF

1 stop8h 07mDelta

Wed 7/306:00 amBUF - MIA

1 stop4h 52mDelta

Deal found 6/30

$217

Tue 7/1512:20 pmMIA - BUF

2 stops11h 18mUnited Airlines

Fri 7/186:00 amBUF - MIA

1 stop5h 49mUnited Airlines

Deal found 7/1

$246

Mon 8/256:20 pmEYW - BUF

1 stop5h 37mDelta

Wed 9/312:02 pmBUF - EYW

1 stop5h 10mDelta

Deal found 7/2

$269

Thu 9/43:45 pmEYW - BUF

1 stop6h 08mAmerican Airlines

Mon 9/88:00 amBUF - EYW

1 stop6h 00mAmerican Airlines

Deal found 7/2

$294

Sun 12/211:00 pmEYW - BUF

1 stop5h 21mUnited Airlines

Tue 1/66:00 amBUF - EYW

1 stop6h 46mUnited Airlines

Deal found 7/1

$409

Last-minute flights from Florida Keys to Buffalo
Discover last-minute flight deals from Florida Keys to Buffalo. Data last updated July 2, 2025 and is based on user searches.

Thu 7/312:20 pmMIA - BUF

2 stops11h 18mUnited Airlines

Sat 7/56:00 amBUF - MIA

1 stop8h 11mUnited Airlines

Deal found 7/1

$232

Wed 7/96:15 amMIA - BUF

1 stop5h 40mSouthwest

Wed 8/612:00 pmBUF - MIA

1 stop4h 40mSouthwest

Deal found 7/1

$206

Wed 7/96:15 pmMIA - BUF

1 stop5h 29mDelta

Wed 7/167:45 pmBUF - MIA

1 stop5h 02mDelta

Deal found 7/1

$236

Wed 7/912:20 pmMIA - BUF

1 stop8h 41mUnited Airlines

Wed 7/166:00 amBUF - MIA

2 stops8h 11mUnited Airlines

Deal found 7/1

$321

Wed 7/94:48 pmEYW - BUF

1 stop7h 44mAmerican Airlines

Tue 7/156:08 amBUF - EYW

1 stop7h 43mAmerican Airlines

Deal found 7/2

$349

Thu 7/106:00 amMIA - BUF

1 stop6h 11mFrontier

Sun 7/139:51 amBUF - MIA

1 stop7h 54mFrontier

Deal found 7/1

$211

Thu 7/107:00 amMIA - BUF

2 stops27h 32mMultiple Airlines

Sun 7/1311:23 amBUF - MIA

3 stops23h 26mMultiple Airlines

Deal found 7/1

$747

Fri 7/116:42 amMIA - BUF

1 stop7h 40mAmerican Airlines

Sun 7/136:28 amBUF - MIA

1 stop4h 30mAmerican Airlines

Deal found 7/1

$406

Tue 7/2212:00 pmMIA - BUF

1 stop6h 40mSouthwest

Sat 7/265:25 pmBUF - MIA

1 stop4h 55mSouthwest

Deal found 7/1

$158

Wed 7/2310:33 amMIA - BUF

1 stop8h 07mDelta

Wed 7/306:00 amBUF - MIA

1 stop4h 52mDelta

Deal found 6/30

$217

Fri 7/258:43 amMIA - BUF

1 stop6h 50mAmerican Airlines

Fri 8/16:28 amBUF - MIA

1 stop4h 30mAmerican Airlines

Deal found 6/30

$159

Wed 8/66:00 amMIA - BUF

1 stop10h 17mFrontier

Sun 8/109:51 amBUF - MIA

1 stop7h 42mFrontier

Deal found 6/30

$184

One-way flights from Florida Keys to Buffalo
Search for one-way flight options from Florida Keys to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 2, 2025.

Fri 8/16:45 amMIA - BUF

1 stop6h 55mSouthwest

Deal found 6/30

$79

Fri 7/185:18 amMIA - BUF

1 stop5h 22mAmerican Airlines

Deal found 6/29

$84

Sat 7/56:00 amMIA - BUF

1 stop6h 11mFrontier

Deal found 6/30

$91

Wed 8/65:58 pmMIA - BUF

1 stop6h 01mDelta

Deal found 6/30

$109

Wed 7/912:20 pmMIA - BUF

2 stops11h 18mUnited Airlines

Deal found 7/1

$133

Thu 8/711:10 amMIA - BUF

2 stops23h 28mMultiple Airlines

Deal found 7/1

$178

Tue 7/86:27 pmEYW - BUF

1 stop5h 32mDelta

Deal found 7/2

$210

Wed 7/92:12 pmEYW - BUF

2 stops9h 32mUnited Airlines

Deal found 7/2

$236

Tue 7/812:01 pmEYW - BUF

2 stops10h 03mAmerican Airlines

Deal found 7/2

$342

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Tue 7/22

12:00 pm-6:40 pm

1 stop6h 40m

Buffalo

Sat 7/26

5:25 pm-10:20 pm

1 stop4h 55m

$158

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fri 7/25

8:43 am-3:33 pm

1 stop6h 50m

Buffalo

Fri 8/1

6:28 am-10:58 am

1 stop4h 30m

$159

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Wed 8/6

6:00 am-4:17 pm

1 stop10h 17m

Buffalo

Sun 8/10

9:51 am-5:33 pm

1 stop7h 42m

$184

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Wed 7/23

10:33 am-6:40 pm

1 stop8h 07m

Buffalo

Wed 7/30

6:00 am-10:52 am

1 stop4h 52m

$217

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Tue 7/15

12:20 pm-11:38 pm

2 stops11h 18m

Buffalo

Fri 7/18

6:00 am-11:49 am

1 stop5h 49m

$246

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Mon 8/25

6:20 pm-11:57 pm

1 stop5h 37m

Buffalo

Tue 9/2

6:00 am-1:05 pm

1 stop7h 05m

$269

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Thu 9/4

3:45 pm-9:53 pm

1 stop6h 08m

Buffalo

Mon 9/8

8:00 am-2:00 pm

1 stop6h 00m

$294

Key WestBuffalo

EYW - BUF

EYWBUF

Key West

Sun 12/21

1:00 pm-6:21 pm

1 stop5h 21m

Buffalo

Tue 1/6

6:00 am-12:46 pm

1 stop6h 46m

$409

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fri 8/1

6:45 am-1:40 pm

1 stop6h 55m

$79

MiamiBuffalo

MIA - BUF

MIABUF

Miami

Fri 7/18

5:18 am-10:40 am

1 stop5h 22m

$84

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 17 results

Best time to book a flight from Florida Keys to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Florida Keys with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Buffalo

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Buffalo

See what other customers who have flown with Southwest, Delta, and United Airlines from Florida Keys to Buffalo have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,272 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,975 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,858 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Frontier

5.9

Fair

3,291 reviews

Southwest

8.0

Very good

4,272 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

What airport do you fly into for flights to Buffalo from Florida Keys?
Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Buffalo.
What are the cheapest airlines to fly from Florida Keys to Buffalo one-way?
The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $79. However, be on the lookout for offers from American Airlines and Frontier, as they are both options that can get you from Florida Keys to Buffalo for a low price.
Can I find deals for flights from Florida Keys to Buffalo that include hotel bookings?
Yes. In addition to deals on Florida Keys to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florida Keys to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Buffalo.
Can I find deals for business class flights from Florida Keys to Buffalo?
Yes. Cheapflights offers flight deals from Florida Keys to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florida Keys to Buffalo?
Currently, January is the cheapest month in which you can book a flight from Florida Keys to Buffalo (average of $256). Flying from Florida Keys to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Williamsville

Orchard Park

Batavia

Eden

Amherst

West Seneca

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Florida Keys to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$208	Average$383	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$259	Average$359	FlexibilityNo cancel fee	On-timeN/A

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$79+ Cheap flights from Florida Keys to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florida Keys to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florida Keys to Buffalo

Keep the following information in mind while searching for Florida Keys to Buffalo flight deals. Data was last updated July 2, 2025.

Round-trip from

One-way from

Find flight deals from Florida Keys to Buffalo

Cheapest flights from Florida Keys to BuffaloExplore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to Buffalo that are best for you.

Best time to book a flight from Florida Keys to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Florida Keys with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Buffalo

Reviews of airlines servicing Buffalo

See what other customers who have flown with Southwest, Delta, and United Airlines from Florida Keys to Buffalo have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Florida Keys?

What are the cheapest airlines to fly from Florida Keys to Buffalo one-way?

Can I find deals for flights from Florida Keys to Buffalo that include hotel bookings?

How can I find direct flights from Florida Keys to Buffalo?

Can I find deals for business class flights from Florida Keys to Buffalo?

What is the cheapest month to book a flight from Florida Keys to Buffalo?

Traveling to a place near Florida Keys?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florida Keys to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Florida Keys to Buffalo

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Book with Flexibility

Travel Smart

Cheapest flights from Florida Keys to Buffalo
Explore the most affordable flight options available from Florida Keys to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.