$124+ Cheap flights from Myrtle Beach to Buffalo (MYR - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BUF
Mar 5 — Mar 121
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Myrtle Beach to BuffaloExplore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:09 am
MYR
- BUF
2 stops27h 45m
Multiple Airlines
Mon 3/211:37 am
BUF
- MYR
1 stop24h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:54 pm
MYR
- BUF
2 stops14h 50m
Multiple Airlines
Mon 3/211:37 am
BUF
- MYR
1 stop24h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:39 pm
MYR
- BUF
1 stop21h 18m
Multiple Airlines
Thu 3/51:39 pm
BUF
- MYR
2 stops18h 34m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:18 pm
MYR
- BUF
1 stop23h 27m
Multiple Airlines
Thu 3/51:39 pm
BUF
- MYR
2 stops18h 34m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:59 pm
MYR
- BUF
2 stops20h 55m
Multiple Airlines
Sat 2/286:40 pm
BUF
- MYR
1 stop17h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:54 pm
MYR
- BUF
2 stops14h 50m
Multiple Airlines
Sat 2/286:40 pm
BUF
- MYR
1 stop17h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2811:54 am
MYR
- BUF
1 stop21h 58m
Multiple Airlines
Mon 3/211:37 am
BUF
- MYR
1 stop24h 07m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:31 am
MYR
- BUF
1 stop7h 00m
Delta
Wed 3/46:35 pm
BUF
- MYR
1 stop5h 22m
Delta
Deal found 2/1![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
MYR
- BUF
2 stops8h 08m
Delta
Tue 3/36:01 am
BUF
- MYR
1 stop5h 34m
Delta
Deal found 2/1![Delta logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:09 am
MYR
- BUF
2 stops27h 45m
Multiple Airlines
Thu 3/512:24 pm
BUF
- MYR
1 stop21h 36m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$305
Best flights from Myrtle Beach to BuffaloDiscover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/251:08 pm
MYR
- BUF
1 stop3h 51m
Delta
Tue 3/36:45 pm
BUF
- MYR
1 stop5h 12m
Delta
Deal found 2/1![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:00 am
MYR
- BUF
1 stop6h 10m
United Airlines
Sun 5/37:00 am
BUF
- MYR
1 stop7h 18m
United Airlines
Deal found 2/1![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:31 am
MYR
- BUF
1 stop7h 00m
Delta
Wed 3/46:35 pm
BUF
- MYR
1 stop5h 22m
Delta
Deal found 2/1![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
MYR
- BUF
2 stops8h 08m
Delta
Tue 3/36:01 am
BUF
- MYR
1 stop5h 34m
Delta
Deal found 2/1![Delta logo]()
$302
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:15 pm
MYR
- BUF
1 stop4h 43m
Delta
Wed 3/46:35 pm
BUF
- MYR
1 stop5h 22m
Delta
Deal found 2/1![Delta logo]()
$328
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
MYR
- BUF
2 stops10h 58m
Delta
Sat 2/286:01 am
BUF
- MYR
1 stop5h 36m
Delta
Deal found 2/1![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:08 pm
MYR
- BUF
1 stop3h 51m
Delta
Wed 3/46:35 pm
BUF
- MYR
1 stop5h 22m
Delta
Deal found 2/1![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:55 pm
MYR
- BUF
1 stop4h 32m
Delta
Wed 3/46:01 am
BUF
- MYR
1 stop5h 34m
Delta
Deal found 2/1![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:15 pm
MYR
- BUF
1 stop4h 43m
Delta
Tue 3/36:45 pm
BUF
- MYR
1 stop5h 12m
Delta
Deal found 2/1![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:31 am
MYR
- BUF
1 stop7h 00m
Delta
Mon 3/26:01 am
BUF
- MYR
1 stop5h 32m
Delta
Deal found 2/1![Delta logo]()
$342
Last-minute flights from Myrtle Beach to BuffaloDiscover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated February 3, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
MYR
- BUF
2 stops8h 08m
Delta
Tue 3/36:01 am
BUF
- MYR
1 stop5h 34m
Delta
Deal found 2/1![Delta logo]()
$302
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
MYR
- BUF
2 stops10h 58m
Delta
Wed 3/42:58 pm
BUF
- MYR
2 stops8h 59m
Delta
Deal found 2/1![Delta logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:09 am
MYR
- BUF
2 stops27h 45m
Multiple Airlines
Mon 3/211:37 am
BUF
- MYR
1 stop24h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:59 pm
MYR
- BUF
2 stops20h 55m
Multiple Airlines
Sat 2/286:40 pm
BUF
- MYR
1 stop17h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:31 am
MYR
- BUF
1 stop7h 00m
Delta
Wed 3/46:35 pm
BUF
- MYR
1 stop5h 22m
Delta
Deal found 2/1![Delta logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:09 am
MYR
- BUF
2 stops27h 45m
Multiple Airlines
Thu 3/512:24 pm
BUF
- MYR
1 stop21h 36m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:54 pm
MYR
- BUF
2 stops14h 50m
Multiple Airlines
Mon 3/211:37 am
BUF
- MYR
1 stop24h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:39 pm
MYR
- BUF
1 stop21h 18m
Multiple Airlines
Thu 3/51:39 pm
BUF
- MYR
2 stops18h 34m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:54 pm
MYR
- BUF
2 stops14h 50m
Multiple Airlines
Sat 2/286:40 pm
BUF
- MYR
1 stop17h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:18 pm
MYR
- BUF
1 stop23h 27m
Multiple Airlines
Thu 3/51:39 pm
BUF
- MYR
2 stops18h 34m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2811:54 am
MYR
- BUF
1 stop21h 58m
Multiple Airlines
Mon 3/211:37 am
BUF
- MYR
1 stop24h 07m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$294
One-way flights from Myrtle Beach to BuffaloSearch for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:54 pm
MYR
- BUF
2 stops38h 11m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$124
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/183:29 pm
MYR
- BUF
1 stop27h 44m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$149
This Trip.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:15 am
MYR
- BUF
1 stop14h 19m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:28 pm
MYR
- BUF
2 stops16h 36m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:09 am
MYR
- BUF
2 stops27h 45m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$167
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:05 pm
MYR
- BUF
1 stop5h 51m
United Airlines
Deal found 2/3![United Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/179:09 am
MYR
- BUF
2 stops9h 12m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$185
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
MYR
- BUF
2 stops8h 07m
Delta
Deal found 2/1![Delta logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/169:09 am
MYR
- BUF
2 stops33h 12m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$191
Find flight deals from Myrtle Beach to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $124 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $441 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.
Fly from
Myrtle Beach
Fly to
Buffalo
Route
Depart
Return
Price
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 2/25
1:08 pm-4:59 pm
1 stop3h 51m
Buffalo
Tue 3/3
6:45 pm-11:57 pm
1 stop5h 12m
$297
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 2/25
10:31 am-5:31 pm
1 stop7h 00m
Buffalo
Wed 3/4
6:35 pm-11:57 pm
1 stop5h 22m
$297
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Tue 2/24
6:00 am-2:08 pm
2 stops8h 08m
Buffalo
Tue 3/3
6:01 am-11:35 am
1 stop5h 34m
$302
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Tue 2/24
12:15 pm-4:58 pm
1 stop4h 43m
Buffalo
Wed 3/4
6:35 pm-11:57 pm
1 stop5h 22m
$328
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Tue 2/24
6:00 am-4:58 pm
2 stops10h 58m
Buffalo
Sat 2/28
6:01 am-11:37 am
1 stop5h 36m
$333
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 2/26
1:08 pm-4:59 pm
1 stop3h 51m
Buffalo
Wed 3/4
6:35 pm-11:57 pm
1 stop5h 22m
$342
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Mon 2/23
6:55 pm-11:27 pm
1 stop4h 32m
Buffalo
Wed 3/4
6:01 am-11:35 am
1 stop5h 34m
$342
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 2/26
12:15 pm-4:58 pm
1 stop4h 43m
Buffalo
Tue 3/3
6:45 pm-11:57 pm
1 stop5h 12m
$342
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 2/25
10:31 am-5:31 pm
1 stop7h 00m
Buffalo
Mon 3/2
6:01 am-11:33 am
1 stop5h 32m
$342
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 4/29
11:00 am-5:10 pm
1 stop6h 10m
Buffalo
Sun 5/3
7:00 am-2:18 pm
1 stop7h 18m
$346
Showing 1-10 of 18 results
Compare providers for flights from Myrtle Beach to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Buffalo in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Myrtle Beach with our price prediction graph.
MYR-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated February 3, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Myrtle Beach to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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Alternative routes for Myrtle Beach to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Myrtle Beach to Buffalo
Discover the top 2 airlines that operate flights from Myrtle Beach to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$346 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$402 | FlexibilityNo cancel fee | On-time63% |