$152+ Cheap flights from Myrtle Beach to Buffalo (MYR - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BUF
Jul 28 — Aug 41
Round-trip
1 adult, Economy
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Cheapest flights from Myrtle Beach to BuffaloExplore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 28, 2026.
Explore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 28, 2026.
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:45 pm
MYR
- BUF
1 stop5h 08m
American Airlines
Sat 7/257:36 pm
BUF
- MYR
1 stop4h 15m
American Airlines
Deal found 6/25![American Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:08 am
MYR
- BUF
1 stop3h 58m
American Airlines
Mon 8/106:50 am
BUF
- MYR
1 stop4h 34m
American Airlines
Deal found 6/28![American Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:15 am
MYR
- BUF
2 stops7h 00m
Southwest
Wed 8/1212:00 pm
BUF
- MYR
1 stop7h 10m
Southwest
Deal found 6/27![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
MYR
- BUF
1 stop5h 12m
Delta
Mon 9/146:05 am
BUF
- MYR
1 stop4h 04m
Delta
Deal found 6/25![Delta logo]()
$320
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:55 am
MYR
- BUF
2 stops9h 10m
Southwest
Mon 9/149:40 am
BUF
- MYR
1 stop4h 10m
Southwest
Deal found 6/25![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
MYR
- BUF
1 stop6h 30m
Southwest
Mon 8/316:00 am
BUF
- MYR
2 stops8h 45m
Southwest
Deal found 6/27![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:10 pm
MYR
- BUF
1 stop4h 41m
American Airlines
Wed 8/56:50 am
BUF
- MYR
1 stop4h 34m
American Airlines
Deal found 6/25![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:14 pm
MYR
- BUF
1 stop3h 45m
American Airlines
Sun 8/306:00 am
BUF
- MYR
1 stop4h 32m
American Airlines
Deal found 6/27![American Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:20 pm
MYR
- BUF
1 stop6h 30m
Southwest
Tue 9/2912:35 pm
BUF
- MYR
2 stops6h 45m
Southwest
Deal found 6/25![Southwest logo]()
$333
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:10 am
MYR
- BUF
1 stop7h 05m
Southwest
Sun 8/309:40 am
BUF
- MYR
2 stops8h 25m
Southwest
Deal found 6/27![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:23 am
MYR
- BUF
1 stop3h 29m
American Airlines
Mon 9/286:30 am
BUF
- MYR
1 stop4h 50m
American Airlines
Deal found 6/25![American Airlines logo]()
$337
Best flights from Myrtle Beach to BuffaloDiscover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 28, 2026.
Discover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 28, 2026.
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
MYR
- BUF
1 stop5h 12m
Delta
Mon 9/146:05 am
BUF
- MYR
1 stop4h 04m
Delta
Deal found 6/25![Delta logo]()
$320
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:55 am
MYR
- BUF
2 stops9h 10m
Southwest
Mon 9/149:40 am
BUF
- MYR
1 stop4h 10m
Southwest
Deal found 6/25![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:23 am
MYR
- BUF
1 stop4h 00m
United Airlines
Wed 10/77:00 am
BUF
- MYR
1 stop8h 16m
United Airlines
Deal found 6/27![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:55 pm
MYR
- BUF
2 stops7h 55m
Southwest
Mon 8/316:00 am
BUF
- MYR
2 stops8h 45m
Southwest
Deal found 6/27![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:55 pm
MYR
- BUF
2 stops7h 55m
Southwest
Sun 9/1311:30 am
BUF
- MYR
1 stop9h 10m
Southwest
Deal found 6/23![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:15 pm
MYR
- BUF
1 stop5h 52m
United Airlines
Thu 10/17:00 am
BUF
- MYR
1 stop8h 16m
United Airlines
Deal found 6/27![United Airlines logo]()
$483
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/272:00 pm
MYR
- BUF
2 stops10h 15m
Southwest
Mon 8/37:35 am
BUF
- MYR
2 stops11h 55m
Southwest
Deal found 6/27![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:30 pm
MYR
- BUF
2 stops8h 10m
Southwest
Sun 9/136:20 am
BUF
- MYR
2 stops7h 45m
Southwest
Deal found 6/23![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:34 am
MYR
- BUF
1 stop3h 51m
United Airlines
Mon 7/206:15 am
BUF
- MYR
1 stop3h 44m
United Airlines
Deal found 6/25![United Airlines logo]()
$523
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:25 am
MYR
- BUF
2 stops9h 35m
Southwest
Wed 8/58:55 am
BUF
- MYR
2 stops10h 25m
Southwest
Deal found 6/25![Southwest logo]()
$421
Last-minute flights from Myrtle Beach to BuffaloDiscover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated June 28, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated June 28, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:45 pm
MYR
- BUF
1 stop5h 08m
American Airlines
Sat 7/257:36 pm
BUF
- MYR
1 stop4h 15m
American Airlines
Deal found 6/25![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:25 am
MYR
- BUF
2 stops9h 35m
Southwest
Sat 7/254:30 pm
BUF
- MYR
1 stop4h 15m
Southwest
Deal found 6/25![Southwest logo]()
$361
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:05 pm
MYR
- BUF
1 stop3h 40m
Southwest
Sat 7/2512:35 pm
BUF
- MYR
2 stops8h 10m
Southwest
Deal found 6/28![Southwest logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/283:53 pm
MYR
- BUF
2 stops22h 00m
Multiple Airlines
Tue 8/49:09 pm
BUF
- MYR
1 stop11h 56m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:30 am
MYR
- BUF
1 stop3h 40m
Southwest
Fri 7/314:10 pm
BUF
- MYR
1 stop6h 40m
Southwest
Deal found 6/28![Southwest logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:17 pm
MYR
- BUF
2 stops19h 12m
Multiple Airlines
Wed 8/57:57 pm
BUF
- MYR
1 stop12h 58m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:42 pm
MYR
- BUF
1 stop25h 50m
Multiple Airlines
Tue 8/49:09 pm
BUF
- MYR
1 stop11h 56m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:10 pm
MYR
- BUF
1 stop4h 41m
American Airlines
Sun 8/25:24 am
BUF
- MYR
1 stop6h 11m
American Airlines
Deal found 6/24![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:10 pm
MYR
- BUF
1 stop4h 41m
American Airlines
Wed 8/56:50 am
BUF
- MYR
1 stop4h 34m
American Airlines
Deal found 6/25![American Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:00 pm
MYR
- BUF
2 stops10h 40m
Southwest
Wed 8/58:55 am
BUF
- MYR
1 stop4h 55m
Southwest
Deal found 6/25![Southwest logo]()
$358
One-way flights from Myrtle Beach to BuffaloSearch for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated June 28, 2026.
Search for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated June 28, 2026.
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:50 am
MYR
- BUF
1 stop7h 25m
Southwest
Deal found 6/26![Southwest logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:21 pm
MYR
- BUF
2 stops18h 08m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$165
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:15 pm
MYR
- BUF
1 stop4h 20m
American Airlines
Deal found 6/24![American Airlines logo]()
$177
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:45 am
MYR
- BUF
1 stop9h 20m
Southwest
Deal found 6/28![Southwest logo]()
$182
This deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:34 am
MYR
- BUF
1 stop3h 51m
United Airlines
Deal found 6/28![United Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:53 pm
MYR
- BUF
2 stops40h 00m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:59 am
MYR
- BUF
2 stops24h 22m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:44 pm
MYR
- BUF
3 stops41h 09m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/109:30 pm
MYR
- BUF
2 stops36h 59m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:17 pm
MYR
- BUF
2 stops29h 27m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$224
Find flight deals from Myrtle Beach to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $303 (American Airlines) |
One-way from | $152 (Southwest) |
Popular in | March |
Cheapest in | September |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Sat 9/12
6:00 am-11:12 am
1 stop5h 12m
Buffalo
Mon 9/14
6:05 am-10:09 am
1 stop4h 04m
$320
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Sat 9/12
11:55 am-9:05 pm
2 stops9h 10m
Buffalo
Mon 9/14
9:40 am-1:50 pm
1 stop4h 10m
$325
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 8/27
1:55 pm-9:50 pm
2 stops7h 55m
Buffalo
Mon 8/31
6:00 am-2:45 pm
2 stops8h 45m
$347
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Fri 9/11
1:55 pm-9:50 pm
2 stops7h 55m
Buffalo
Sun 9/13
11:30 am-8:40 pm
1 stop9h 10m
$364
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Mon 7/27
2:00 pm-12:15 am
2 stops10h 15m
Buffalo
Mon 8/3
7:35 am-7:30 pm
2 stops11h 55m
$406
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 9/10
2:30 pm-10:40 pm
2 stops8h 10m
Buffalo
Sun 9/13
6:20 am-2:05 pm
2 stops7h 45m
$412
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 7/29
10:25 am-8:00 pm
2 stops9h 35m
Buffalo
Wed 8/5
8:55 am-7:20 pm
2 stops10h 25m
$421
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Tue 10/6
10:23 am-2:23 pm
1 stop4h 00m
Buffalo
Wed 10/7
7:00 am-3:16 pm
1 stop8h 16m
$459
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 9/23
3:15 pm-9:07 pm
1 stop5h 52m
Buffalo
Thu 10/1
7:00 am-3:16 pm
1 stop8h 16m
$483
Quickest round-trip
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 7/16
10:34 am-2:25 pm
1 stop3h 51m
Buffalo
Mon 7/20
6:15 am-9:59 am
1 stop3h 44m
$523
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Buffalo in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Myrtle Beach with our price prediction graph.
MYR-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated June 28, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Myrtle Beach to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Batavia
Williamsville
Orchard Park
Eden
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Myrtle Beach and Buffalo flights
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Buffalo
Discover the top 2 airlines that operate flights from Myrtle Beach to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$372 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$380 | FlexibilityNo cancel fee | On-time63% |