$145+ Cheap flights from Myrtle Beach to Buffalo (MYR - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BUF
Sep 5 — Sep 121
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Buffalo
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Best
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Cheapest flights from Myrtle Beach to BuffaloExplore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
Explore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:41 pm -
2 stops37h 48m
Wed 9/26:54 pm -
1 stop14h 01m
Deal found 8/2![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:07 pm -
2 stops37h 22m
Tue 9/19:29 pm -
1 stop15h 18m
Deal found 8/2![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:13 pm -
1 stop25h 56m
Fri 9/46:54 pm -
1 stop14h 11m
Deal found 8/2![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:10 pm -
1 stop4h 30m
Fri 9/1111:48 am -
1 stop7h 01m
Deal found 8/3![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:55 am -
2 stops8h 50m
Fri 9/113:55 pm -
1 stop3h 50m
Deal found 8/5![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:14 pm -
1 stop3h 45m
Thu 9/104:31 pm -
1 stop4h 37m
Deal found 8/6![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:08 am -
2 stops8h 52m
Tue 9/87:00 am -
1 stop7h 17m
Deal found 8/5![United Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 pm -
1 stop4h 02m
Sun 9/275:37 am -
1 stop6h 00m
Deal found 8/5![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:00 am -
2 stops10h 10m
Sat 10/33:40 pm -
1 stop3h 50m
Deal found 8/5![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:55 pm -
2 stops8h 55m
Tue 12/112:45 pm -
1 stop5h 40m
Deal found 8/5![Southwest logo]()
$334
Best flights from Myrtle Beach to BuffaloDiscover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
Discover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:55 am -
2 stops8h 50m
Fri 9/113:55 pm -
1 stop3h 50m
Deal found 8/3![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:56 pm -
1 stop4h 56m
Sun 10/46:59 pm -
1 stop4h 29m
Deal found 8/5![Delta logo]()
$344
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:25 am -
1 stop5h 22m
Sun 1/107:00 am -
1 stop7h 33m
Deal found 8/4![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 pm -
1 stop3h 50m
Mon 10/55:45 pm -
1 stop3h 40m
Deal found 8/4![Southwest logo]()
$343
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:25 pm -
1 stop6h 30m
Sun 12/65:20 am -
2 stops7h 40m
Deal found 8/2![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:40 am -
1 stop4h 30m
Thu 9/106:00 am -
2 stops8h 45m
Deal found 8/6![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:55 pm -
1 stop3h 50m
Wed 12/306:00 am -
1 stop4h 00m
Deal found 8/5![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:30 pm -
2 stops8h 15m
Mon 9/76:00 am -
2 stops8h 45m
Deal found 8/3![Southwest logo]()
$417
Last-minute flights from Myrtle Beach to BuffaloDiscover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated August 6, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated August 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:07 pm -
2 stops37h 22m
Tue 9/19:29 pm -
1 stop15h 18m
Deal found 8/2![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:41 pm -
2 stops37h 48m
Wed 9/26:54 pm -
1 stop14h 01m
Deal found 8/2![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:13 pm -
1 stop25h 56m
Fri 9/46:54 pm -
1 stop14h 11m
Deal found 8/2![Multiple Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:08 am -
2 stops8h 52m
Tue 9/87:00 am -
1 stop7h 17m
Deal found 8/5![United Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:14 pm -
1 stop3h 45m
Thu 9/104:31 pm -
1 stop4h 37m
Deal found 8/6![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:14 pm -
1 stop5h 48m
Sat 9/53:40 pm -
1 stop5h 46m
Deal found 8/3![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:10 pm -
1 stop4h 30m
Fri 9/1111:48 am -
1 stop7h 01m
Deal found 8/3![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:55 am -
2 stops8h 50m
Fri 9/113:55 pm -
1 stop3h 50m
Deal found 8/5![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 pm -
1 stop4h 02m
Sun 9/275:37 am -
1 stop6h 00m
Deal found 8/5![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:00 am -
2 stops10h 10m
Sat 10/33:40 pm -
1 stop3h 50m
Deal found 8/5![Southwest logo]()
$330
One-way flights from Myrtle Beach to BuffaloSearch for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
Search for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:45 am -
1 stop7h 04m
Deal found 8/3![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:41 pm -
2 stops37h 48m
Deal found 8/6![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:41 pm -
2 stops37h 48m
Deal found 8/2![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops42h 06m
Deal found 8/4![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:07 pm -
2 stops37h 22m
Deal found 8/2![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:30 pm -
2 stops37h 59m
Deal found 8/6![Frontier logo]()
$155
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:20 pm -
1 stop4h 36m
Deal found 8/3![American Airlines logo]()
$160
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:40 am -
1 stop4h 30m
Deal found 8/6![Southwest logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:13 pm -
2 stops18h 16m
Deal found 8/3![Multiple Airlines logo]()
$164
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am -
2 stops7h 00m
Deal found 8/3![Southwest logo]()
$165
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:10 am -
1 stop7h 05m
Deal found 8/2![Southwest logo]()
$181
Find flight deals from Myrtle Beach to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (Kiwi.com) |
One-way from | $145 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $379 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Sat 9/5
7:55 am-4:45 pm
2 stops8h 50m
Buffalo
Fri 9/11
3:55 pm-7:45 pm
1 stop3h 50m
$322
Quickest round-trip
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Fri 10/2
7:50 pm-11:40 pm
1 stop3h 50m
Buffalo
Mon 10/5
5:45 pm-9:25 pm
1 stop3h 40m
$343
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Thu 10/1
6:56 pm-11:52 pm
1 stop4h 56m
Buffalo
Sun 10/4
6:59 pm-11:28 pm
1 stop4h 29m
$344
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Thu 12/3
3:25 pm-9:55 pm
1 stop6h 30m
Buffalo
Sun 12/6
5:20 am-1:00 pm
2 stops7h 40m
$349
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Thu 9/3
6:40 am-11:10 am
1 stop4h 30m
Buffalo
Thu 9/10
6:00 am-2:45 pm
2 stops8h 45m
$358
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Wed 12/23
2:55 pm-6:45 pm
1 stop3h 50m
Buffalo
Wed 12/30
6:00 am-10:00 am
1 stop4h 00m
$399
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Fri 9/4
2:30 pm-10:45 pm
2 stops8h 15m
Buffalo
Mon 9/7
6:00 am-2:45 pm
2 stops8h 45m
$417
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Thu 1/7
11:25 am-4:47 pm
1 stop5h 22m
Buffalo
Sun 1/10
7:00 am-2:33 pm
1 stop7h 33m
$424
Cheapest one-way
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Tue 9/15
10:45 am-5:49 pm
1 stop7h 04m
$145
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Fri 9/4
8:41 pm-10:29 am
2 stops37h 48m
$147
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Buffalo in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Myrtle Beach with our price prediction graph.
MYR-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated August 6, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Myrtle Beach to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 6, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Myrtle Beach to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and Buffalo flights
Browse other Myrtle Beach and Buffalo flight options. Last updated on August 6, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on August 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Buffalo
Discover the top 2 airlines that operate flights from Myrtle Beach to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$375 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$380 | FlexibilityNo cancel fee | On-time63% |