$141+ Cheap flights from Myrtle Beach to Buffalo (MYR - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BUF
Jun 30 — Jul 71
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Myrtle Beach to BuffaloExplore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
Explore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:00 am
MYR
- BUF
1 stop6h 30m
Delta
Mon 8/316:40 am
BUF
- MYR
1 stop3h 58m
Delta
Deal found 5/29![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:02 am
MYR
- BUF
1 stop5h 52m
American Airlines
Mon 8/315:00 am
BUF
- MYR
2 stops6h 24m
American Airlines
Deal found 5/29![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:33 am
MYR
- BUF
1 stop3h 40m
Delta
Wed 7/157:24 pm
BUF
- MYR
1 stop4h 31m
Delta
Deal found 5/27![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:16 pm
MYR
- BUF
2 stops7h 43m
American Airlines
Wed 7/1512:45 pm
BUF
- MYR
1 stop5h 52m
American Airlines
Deal found 5/28![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:45 pm
MYR
- BUF
1 stop5h 13m
Delta
Sun 9/136:00 am
BUF
- MYR
1 stop4h 09m
Delta
Deal found 5/29![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:20 pm
MYR
- BUF
1 stop4h 36m
American Airlines
Mon 8/314:49 pm
BUF
- MYR
1 stop5h 49m
American Airlines
Deal found 5/30![American Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/254:13 pm
MYR
- BUF
1 stop26h 54m
Multiple Airlines
Sun 8/308:57 pm
BUF
- MYR
1 stop10h 53m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:20 am
MYR
- BUF
1 stop6h 30m
Southwest
Mon 10/1212:25 pm
BUF
- MYR
1 stop7h 05m
Southwest
Deal found 5/29![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:50 am
MYR
- BUF
2 stops7h 35m
Southwest
Sun 9/139:40 am
BUF
- MYR
1 stop4h 30m
Southwest
Deal found 5/29![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:05 pm
MYR
- BUF
1 stop3h 40m
Southwest
Fri 7/172:50 pm
BUF
- MYR
1 stop3h 45m
Southwest
Deal found 5/27![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:15 am
MYR
- BUF
1 stop4h 15m
Southwest
Sun 8/309:40 am
BUF
- MYR
2 stops8h 25m
Southwest
Deal found 5/26![Southwest logo]()
$358
Best flights from Myrtle Beach to BuffaloDiscover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
Discover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:16 pm
MYR
- BUF
2 stops7h 43m
American Airlines
Wed 7/1512:45 pm
BUF
- MYR
1 stop5h 52m
American Airlines
Deal found 5/28![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:20 am
MYR
- BUF
1 stop6h 30m
Southwest
Mon 10/1212:25 pm
BUF
- MYR
1 stop7h 05m
Southwest
Deal found 5/29![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:51 pm
MYR
- BUF
1 stop4h 50m
Delta
Sun 8/26:29 am
BUF
- MYR
1 stop4h 10m
Delta
Deal found 5/30![Delta logo]()
$387
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:25 pm
MYR
- BUF
1 stop5h 12m
United Airlines
Thu 10/297:00 am
BUF
- MYR
1 stop7h 33m
United Airlines
Deal found 5/27![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:20 am
MYR
- BUF
1 stop4h 20m
Southwest
Fri 10/235:05 am
BUF
- MYR
2 stops7h 35m
Southwest
Deal found 5/28![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:15 am
MYR
- BUF
1 stop4h 15m
Southwest
Sun 8/309:40 am
BUF
- MYR
2 stops8h 25m
Southwest
Deal found 5/26![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:30 pm
MYR
- BUF
2 stops8h 10m
Southwest
Mon 8/316:00 am
BUF
- MYR
2 stops8h 45m
Southwest
Deal found 5/30![Southwest logo]()
$383
Last-minute flights from Myrtle Beach to BuffaloDiscover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated May 31, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated May 31, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/134:21 pm
MYR
- BUF
2 stops18h 19m
Multiple Airlines
Tue 6/169:02 pm
BUF
- MYR
1 stop12h 03m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:17 pm
MYR
- BUF
1 stop6h 33m
American Airlines
Sun 6/215:33 am
BUF
- MYR
1 stop6h 04m
American Airlines
Deal found 5/27![American Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:10 pm
MYR
- BUF
1 stop4h 00m
Southwest
Fri 6/264:10 pm
BUF
- MYR
1 stop6h 35m
Southwest
Deal found 5/28![Southwest logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:28 pm
MYR
- BUF
1 stop28h 44m
Multiple Airlines
Wed 7/12:50 pm
BUF
- MYR
2 stops24h 24m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:28 pm
MYR
- BUF
1 stop28h 44m
Multiple Airlines
Thu 7/211:35 am
BUF
- MYR
2 stops44h 26m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:54 pm
MYR
- BUF
1 stop4h 56m
Delta
Tue 6/306:29 am
BUF
- MYR
1 stop4h 08m
Delta
Deal found 5/27![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:32 am
MYR
- BUF
1 stop3h 49m
Delta
Thu 7/210:20 am
BUF
- MYR
1 stop6h 46m
Delta
Deal found 5/27![Delta logo]()
$393
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:45 pm
MYR
- BUF
1 stop5h 09m
American Airlines
Tue 6/3012:49 pm
BUF
- MYR
1 stop4h 50m
American Airlines
Deal found 5/27![American Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:42 pm
MYR
- BUF
1 stop28h 30m
Multiple Airlines
Wed 7/12:50 pm
BUF
- MYR
2 stops24h 24m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:42 pm
MYR
- BUF
1 stop28h 30m
Multiple Airlines
Thu 7/211:35 am
BUF
- MYR
2 stops44h 26m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:00 pm
MYR
- BUF
2 stops10h 10m
Southwest
Sun 6/281:20 pm
BUF
- MYR
1 stop9h 25m
Southwest
Deal found 5/27![Southwest logo]()
$418
One-way flights from Myrtle Beach to BuffaloSearch for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
Search for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:10 pm
MYR
- BUF
1 stop4h 30m
American Airlines
Deal found 5/29![American Airlines logo]()
$141
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:30 pm
MYR
- BUF
2 stops7h 20m
Southwest
Deal found 5/29![Southwest logo]()
$157
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:15 pm
MYR
- BUF
1 stop4h 20m
American Airlines
Deal found 5/26![American Airlines logo]()
$169
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:00 am
MYR
- BUF
1 stop6h 23m
Delta
Deal found 5/29![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:20 pm
MYR
- BUF
1 stop5h 05m
Southwest
Deal found 5/29![Southwest logo]()
$180
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:30 pm
MYR
- BUF
2 stops8h 10m
Southwest
Deal found 5/29![Southwest logo]()
$182
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:07 pm
MYR
- BUF
1 stop4h 52m
American Airlines
Deal found 5/30![American Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:30 am
MYR
- BUF
2 stops8h 05m
Southwest
Deal found 5/29![Southwest logo]()
$199
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:15 am
MYR
- BUF
2 stops13h 10m
Southwest
Deal found 5/26![Southwest logo]()
$205
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:45 pm
MYR
- BUF
1 stop4h 10m
Southwest
Deal found 5/28![Southwest logo]()
$214
Find flight deals from Myrtle Beach to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Delta) |
One-way from | $141 (Delta) |
Popular in | March |
Cheapest in | January |
Average price | $380 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 7/8
4:16 pm-11:59 pm
2 stops7h 43m
Buffalo
Wed 7/15
12:45 pm-6:37 pm
1 stop5h 52m
$324
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 10/7
8:20 am-2:50 pm
1 stop6h 30m
Buffalo
Mon 10/12
12:25 pm-7:30 pm
1 stop7h 05m
$349
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Tue 10/20
8:20 am-12:40 pm
1 stop4h 20m
Buffalo
Fri 10/23
5:05 am-12:40 pm
2 stops7h 35m
$358
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Tue 8/25
8:15 am-12:30 pm
1 stop4h 15m
Buffalo
Sun 8/30
9:40 am-6:05 pm
2 stops8h 25m
$358
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Fri 8/14
2:30 pm-10:40 pm
2 stops8h 10m
Buffalo
Mon 8/31
6:00 am-2:45 pm
2 stops8h 45m
$383
Quickest round-trip
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 7/30
1:51 pm-6:41 pm
1 stop4h 50m
Buffalo
Sun 8/2
6:29 am-10:39 am
1 stop4h 10m
$387
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Wed 10/28
5:25 pm-10:37 pm
1 stop5h 12m
Buffalo
Thu 10/29
7:00 am-2:33 pm
1 stop7h 33m
$408
Cheapest one-way
Quickest one-way
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Thu 9/10
6:15 pm-10:35 pm
1 stop4h 20m
$169
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Fri 9/11
11:00 am-5:23 pm
1 stop6h 23m
$177
Myrtle BeachBuffalo
MYR - BUF
MYRBUF
Myrtle Beach Intl
Sun 6/28
6:30 am-2:35 pm
2 stops8h 05m
$199
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Buffalo in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Myrtle Beach with our price prediction graph.
MYR-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Buffalo
What is the cheapest month to book a flight from Myrtle Beach to Buffalo?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Buffalo (average of $290). Flying from Myrtle Beach to Buffalo in March is currently the most expensive (average of $584). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to Buffalo?
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated May 31, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Myrtle Beach to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
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Williamsville
Orchard Park
Eden
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Top 2 airlines flying from Myrtle Beach to Buffalo
Discover the top 2 airlines that operate flights from Myrtle Beach to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$354 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$376 | FlexibilityNo cancel fee | On-time63% |