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$525+ Cheap flights from South Carolina to Brussels

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
nov. 13 — nov. 201
jue. 11/13
jue. 11/20
1 adult, Economy
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Cheap flight deals from South Carolina to Brussels

Keep the following information in mind while searching for South Carolina to Brussels flight deals. Data was last updated octubre 14, 2025.

Round-trip from

$525
(FlightHub)
From South Carolina to Brussels
Search Deals

Find flight deals from South Carolina to Brussels

Cheapest flights from South Carolina to Brussels
Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 14, 2025.

This FlightHub deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/36:00 amCLT - BRU
2 stops21h 40mScandinavian Airlines
vie. 11/2110:20 amBRU - CLT
2 stops17h 06mScandinavian Airlines
Deal found 10/13$525
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/282:52 pmCHS - BRU
2 stops16h 23mUnited Airlines
vie. 12/510:00 amBRU - CHS
2 stops39h 45mUnited Airlines
Deal found 10/14$530
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2810:20 amCAE - BRU
2 stops20h 55mUnited Airlines
vie. 12/510:00 amBRU - CAE
2 stops36h 43mUnited Airlines
Deal found 10/14$530
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/126:15 amCHS - BRU
1 stop20h 40mUnited Airlines
mié. 11/1910:00 amBRU - CHS
2 stops41h 08mUnited Airlines
Deal found 10/13$533
This Scandinavian Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/276:00 amCLT - BRU
2 stops26h 30mScandinavian Airlines
jue. 12/410:20 amBRU - CLT
2 stops18h 26mScandinavian Airlines
Deal found 10/13$540
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/102:52 pmCHS - BRU
2 stops16h 23mUnited Airlines
dom. 11/1611:55 amBRU - CHS
1 stop33h 14mUnited Airlines
Deal found 10/13$546
This Scandinavian Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:00 amCLT - BRU
2 stops21h 40mScandinavian Airlines
lun. 11/1710:20 amBRU - CLT
2 stops17h 06mScandinavian Airlines
Deal found 10/13$547
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/16:50 pmCLT - BRU
1 stop12h 20mLufthansa
mar. 12/169:35 amBRU - CLT
1 stop13h 20mLufthansa
Deal found 10/12$561
This Air Canada deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/126:00 amCHS - BRU
3 stops19h 50mMultiple Airlines
mié. 11/1910:00 amBRU - CHS
2 stops19h 42mMultiple Airlines
Deal found 10/13$563
This Gotogate deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/15:05 pmCLT - BRU
2 stops33h 50mAir Canada
mar. 12/1610:00 amBRU - CLT
2 stops36h 17mAir Canada
Deal found 10/12$568
This Gotogate deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/16:50 pmCLT - BRU
1 stop12h 20mMultiple Airlines
mar. 12/1610:00 amBRU - CLT
2 stops16h 57mMultiple Airlines
Deal found 10/12$576
This Scandinavian Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1910:02 amCLT - BRU
2 stops17h 38mScandinavian Airlines
lun. 11/2410:20 amBRU - CLT
2 stops19h 30mScandinavian Airlines
Deal found 10/13$577

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels that are best for you.

Fly from

South Carolina

Fly to

Brussels

Route

Depart

Return

Price

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

vie. 11/28

2:52 pm-1:15 pm

2 stops16h 23m

Brussels Bruxelles-National

vie. 12/5

10:00 am-7:45 pm

2 stops39h 45m

$530

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

vie. 11/28

10:20 am-1:15 pm

2 stops20h 55m

Brussels Bruxelles-National

vie. 12/5

10:00 am-4:43 pm

2 stops36h 43m

$530

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

lun. 1/12

1:25 pm-7:50 am

2 stops36h 25m

Brussels Bruxelles-National

sáb. 1/24

10:00 am-12:41 pm

2 stops32h 41m

$533

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

mié. 11/12

6:00 am-7:50 am

2 stops19h 50m

Brussels Bruxelles-National

mié. 11/19

10:00 am-5:54 pm

2 stops37h 54m

$533

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

mié. 11/12

6:15 am-8:55 am

1 stop20h 40m

Brussels Bruxelles-National

mié. 11/19

10:00 am-9:08 pm

2 stops41h 08m

$533

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

jue. 11/27

6:00 am-2:30 pm

2 stops26h 30m

Brussels Bruxelles-National

jue. 12/4

10:20 am-10:46 pm

2 stops18h 26m

$540

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

lun. 11/10

2:52 pm-1:15 pm

2 stops16h 23m

Brussels Bruxelles-National

dom. 11/16

10:00 am-8:56 am

2 stops28h 56m

$546

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

jue. 3/12

10:00 am-7:50 pm

2 stops28h 50m

Brussels Bruxelles-National

lun. 3/23

10:20 am-10:23 pm

2 stops17h 03m

$547

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

lun. 11/10

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

lun. 11/17

10:20 am-9:26 pm

2 stops17h 06m

$547

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

mar. 3/10

1:15 pm-2:30 pm

2 stops20h 15m

Brussels Bruxelles-National

mié. 3/18

7:15 pm-11:54 pm

2 stops33h 39m

$555

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 26 results
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Best time to book a flight from South Carolina to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels

What is the cheapest time of day to fly from SC to BRU?

Find hourly flight availability from South Carolina to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 14, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Brussels in the morning. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Brussels?

    There are many flights that can get you from South Carolina to Brussels in 16h 23m. Fly via United Airlines, Air Canada, or Scandinavian Airlines to get the fastest option. South Carolina and Brussels are separated by a distance of 4269 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Brussels?

    While some choose either Charleston - Brussels Bruxelles-National or Myrtle Beach Intl - Brussels Bruxelles-National, Charlotte Douglas - Brussels Bruxelles-National is the most popular route from South Carolina to Brussels.

  • Can I find deals for flights from South Carolina to Brussels that include hotel bookings?

    Yes. In addition to deals on South Carolina to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Brussels.

  • Can I find deals for business class flights from South Carolina to Brussels?

    Yes. Cheapflights offers flight deals from South Carolina to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Brussels

Discover the top airline that operate flights from South Carolina to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$606Average$1,043FlexibilityNo cancel feeOn-time69%

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