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$293+ Cheap flights from South Carolina to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from South Carolina to Brussels

Keep the following information in mind while searching for South Carolina to Brussels flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$521
(Gotogate)

One-way from

$293
(Kiwi.com)
From South Carolina to Brussels
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One-way flight from South Carolina to Brussels
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Find flight deals from South Carolina to Brussels

Cheapest flights from South Carolina to Brussels
Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Gotogate deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/193:15 pmCLT - BRU
1 stop10h 35mAir Canada
mar. 11/410:00 amBRU - CLT
2 stops16h 57mAir Canada
Deal found 9/11$521
This Rumbo deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/196:00 amCLT - BRU
2 stops21h 40mScandinavian Airlines
mar. 11/410:20 amBRU - CLT
2 stops17h 27mScandinavian Airlines
Deal found 9/10$522
This Booking.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/208:30 amCLT - BRU
1 stop17h 20mAir Canada
mar. 11/410:00 amBRU - CLT
2 stops16h 57mAir Canada
Deal found 9/9$530
This Flighttix deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/1910:34 amCLT - BRU
1 stop14h 41mLufthansa
mar. 11/411:55 amBRU - CLT
1 stop12h 56mLufthansa
Deal found 9/11$534
This oojo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/192:52 pmCAE - BRU
1 stop10h 23mBrussels Airlines
vie. 10/1012:00 pmBRU - CAE
1 stop13h 01mBrussels Airlines
Deal found 9/11$921
This Brussels Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/182:52 pmCAE - BRU
1 stop10h 23mBrussels Airlines
vie. 10/1012:00 pmBRU - CAE
1 stop13h 01mBrussels Airlines
Deal found 9/11$927
This Brussels Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/202:52 pmCAE - BRU
1 stop10h 33mBrussels Airlines
vie. 10/108:00 amBRU - CAE
2 stops17h 01mBrussels Airlines
Deal found 9/11$957
This Brussels Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/182:52 pmCAE - BRU
1 stop10h 23mBrussels Airlines
jue. 10/912:00 pmBRU - CAE
1 stop13h 01mBrussels Airlines
Deal found 9/11$1,102
This Brussels Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/182:52 pmCAE - BRU
1 stop10h 33mBrussels Airlines
sáb. 10/118:00 amBRU - CAE
2 stops17h 01mBrussels Airlines
Deal found 9/11$1,117
This Brussels Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/202:52 pmCAE - BRU
2 stops14h 08mBrussels Airlines
jue. 10/96:25 amBRU - CAE
2 stops18h 36mBrussels Airlines
Deal found 9/11$1,451
This Brussels Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/202:52 pmCAE - BRU
2 stops14h 08mBrussels Airlines
sáb. 10/116:25 amBRU - CAE
2 stops18h 36mBrussels Airlines
Deal found 9/11$1,611
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/262:52 pmCHS - BRU
2 stops34h 58mMultiple Airlines
lun. 12/17:10 pmBRU - CHS
2 stops34h 32mMultiple Airlines
Deal found 9/10$3,228

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels that are best for you.

Fly from

South Carolina

Fly to

Brussels

Route

Depart

Return

Price

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

mar. 3/10

2:50 pm-7:15 am

1 stop11h 25m

Brussels Bruxelles-National

mié. 3/18

10:00 am-12:48 pm

2 stops31h 48m

$534

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

dom. 10/19

10:34 am-7:15 am

1 stop14h 41m

Brussels Bruxelles-National

mar. 11/4

11:55 am-6:51 pm

1 stop12h 56m

$534

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

lun. 10/20

3:15 pm-1:15 pm

2 stops16h 00m

Brussels Bruxelles-National

mar. 11/4

10:00 am-8:57 pm

2 stops16h 57m

$534

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

dom. 10/19

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

mar. 11/4

10:20 am-9:47 pm

2 stops17h 27m

$540

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

mar. 3/10

10:40 am-7:50 am

2 stops16h 10m

Brussels Bruxelles-National

mié. 3/18

10:00 am-11:29 pm

2 stops18h 29m

$547

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

mar. 3/10

10:00 am-7:50 pm

2 stops28h 50m

Brussels Bruxelles-National

mié. 3/18

10:20 am-10:23 pm

2 stops17h 03m

$547

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

vie. 10/24

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

jue. 10/30

10:20 am-9:47 pm

2 stops16h 27m

$548

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

mié. 11/26

2:52 pm-7:50 am

2 stops34h 58m

Brussels Bruxelles-National

lun. 12/1

7:10 pm-11:42 pm

2 stops34h 32m

$3,228

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

mié. 11/26

6:35 pm-8:05 am

1 stop31h 30m

Brussels Bruxelles-National

lun. 12/1

7:10 pm-5:57 pm

2 stops28h 47m

$3,247

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

mar. 12/2

2:15 pm-10:10 pm

2 stops25h 55m

Brussels Bruxelles-National

sáb. 12/6

3:15 pm-10:23 pm

2 stops37h 08m

$3,325

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 22 results
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Best time to book a flight from South Carolina to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels

What is the cheapest time of day to fly from SC to BRU?

Find hourly flight availability from South Carolina to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Brussels as you normally would.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Brussels?

    There are many flights that can get you from South Carolina to Brussels in 11h 25m. Fly via United Airlines, Lufthansa, or Turkish Airlines to get the fastest option. South Carolina and Brussels are separated by a distance of 4194 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Brussels?

    While some choose either Charleston - Brussels Bruxelles-National or Myrtle Beach Intl - Brussels Bruxelles-National, Charlotte Douglas - Brussels Bruxelles-National is the most popular route from South Carolina to Brussels.

  • Can I find deals for flights from South Carolina to Brussels that include hotel bookings?

    Yes. In addition to deals on South Carolina to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Brussels.

  • Can I find deals for business class flights from South Carolina to Brussels?

    Yes. Cheapflights offers flight deals from South Carolina to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Brussels?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Brussels (average of $614). Flying from South Carolina to Brussels in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Brussels

Discover the top airline that operate flights from South Carolina to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$551Average$998FlexibilityNo cancel feeOn-time69%

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