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$317+ Cheap flights from South Carolina to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from South Carolina to Brussels

Keep the following information in mind while searching for South Carolina to Brussels flight deals. Data was last updated May 1, 2025.

Round-trip from

$554
(Delta)

One-way from

$317
(Kiwi.com)
From South Carolina to Brussels
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One-way flight from South Carolina to Brussels
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Find flight deals from South Carolina to Brussels

Cheapest flights from South Carolina to Brussels
Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/192:20 pmCLT - BRU
1 stop12h 20mDelta
Tue 8/2610:45 amBRU - CLT
1 stop18h 12mDelta
Deal found 4/29$554
This oojo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/116:00 pmCLT - BRU
2 stops14h 20mBritish Airways
Mon 8/189:15 pmBRU - CLT
2 stops24h 35mBritish Airways
Deal found 4/30$568
This Air Canada deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 amCHS - BRU
2 stops19h 55mAir Canada
Tue 12/210:00 amBRU - CHS
2 stops43h 19mAir Canada
Deal found 4/30$581
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/232:30 pmCHS - BRU
1 stop10h 45mUnited Airlines
Tue 12/210:00 amBRU - CHS
2 stops17h 04mUnited Airlines
Deal found 4/30$604
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1911:22 amCLT - BRU
2 stops14h 38mUnited Airlines
Tue 8/2610:00 amBRU - CLT
2 stops34h 09mUnited Airlines
Deal found 4/29$611
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amCLT - BRU
2 stops19h 55mMultiple Airlines
Mon 12/14:30 pmBRU - CLT
1 stop30h 25mMultiple Airlines
Deal found 4/30$612
This FlightHub deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/86:00 amCLT - BRU
2 stops21h 40mScandinavian Airlines
Wed 9/174:00 pmBRU - CLT
2 stops35h 02mScandinavian Airlines
Deal found 4/30$627
This United deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:40 pmCHS - BRU
1 stop29h 35mMultiple Airlines
Mon 12/12:50 pmBRU - CHS
2 stops34h 04mMultiple Airlines
Deal found 4/30$632
This Lufthansa deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:00 pmCHS - BRU
2 stops16h 10mLufthansa
Mon 12/17:40 pmBRU - CHS
2 stops33h 39mLufthansa
Deal found 4/30$662
This Virgin Atlantic deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/185:17 pmCLT - BRU
1 stop33h 23mVirgin Atlantic
Tue 6/310:45 amBRU - CLT
1 stop29h 10mVirgin Atlantic
Deal found 4/30$706
This Gotogate deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/183:15 pmCLT - BRU
2 stops12h 30mAir Canada
Tue 6/310:00 amBRU - CLT
2 stops17h 21mAir Canada
Deal found 4/30$776
This United deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:15 pmMYR - BRU
1 stop11h 45mMultiple Airlines
Tue 5/2010:00 amBRU - MYR
2 stops36h 11mMultiple Airlines
Deal found 4/30$866

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels that are best for you.

Fly from

South Carolina

Fly to

Brussels

Route

Depart

Return

Price

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 8/19

2:20 pm-8:40 am

1 stop12h 20m

Brussels Bruxelles-National

Tue 8/26

10:45 am-10:57 pm

1 stop18h 12m

$554

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 8/11

6:00 pm-2:20 pm

2 stops14h 20m

Brussels Bruxelles-National

Mon 8/18

9:15 pm-3:50 pm

2 stops24h 35m

$568

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 8/19

11:22 am-8:00 am

2 stops14h 38m

Brussels Bruxelles-National

Tue 8/26

10:00 am-2:09 pm

2 stops34h 09m

$611

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 9/8

8:10 pm-7:35 pm

1 stop17h 25m

Brussels Bruxelles-National

Wed 9/17

7:05 am-4:05 pm

1 stop15h 00m

$616

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 9/8

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

Wed 9/17

4:00 pm-9:02 pm

2 stops35h 02m

$627

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 5/18

5:17 pm-8:40 am

1 stop33h 23m

Brussels Bruxelles-National

Tue 6/3

10:45 am-9:55 am

1 stop29h 10m

$706

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 5/18

3:15 pm-9:45 am

2 stops12h 30m

Brussels Bruxelles-National

Tue 6/3

10:00 am-9:21 pm

2 stops17h 21m

$776

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 7/23

6:15 am-8:00 am

2 stops19h 45m

Brussels Bruxelles-National

Tue 7/29

10:00 am-2:25 pm

2 stops34h 25m

$856

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Fri 5/16

3:15 pm-9:00 am

1 stop11h 45m

Brussels Bruxelles-National

Tue 5/20

10:00 am-4:11 pm

2 stops36h 11m

$866

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Fri 5/16

11:08 am-9:45 am

2 stops16h 37m

Brussels Bruxelles-National

Tue 5/20

10:00 am-4:11 pm

2 stops36h 11m

$870

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels

What is the cheapest time of day to fly from SC to BRU?

Find hourly flight availability from South Carolina to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Brussels as you normally would.

Rainfall in Brussels by month

Plan your trip to Brussels by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Brussels ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels when rainfall is around 1.6 in.

Temperature in Brussels by month

Plan your trip to Brussels by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Brussels, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated May 1, 2025.
Read through reviews of airlines operating flights from South Carolina to Brussels, such as Delta, KLM and Austrian Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Austrian Airlines
7.6
Good
781 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
SWISS
7.5
Good
1,588 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Brussels one-way?

    To fly one-way, consider booking your trip with British Airways, which is currently one of the cheapest options available, starting at $418. KLM flights start at $723 while deals on Brussels Airlines start at $824 one-way.

  • What are the most popular routes from South Carolina to Brussels?

    While some choose either Charleston - Brussels Bruxelles-National or Columbia Metropolitan - Brussels Bruxelles-National, Charlotte Douglas - Brussels Bruxelles-National is the most popular route from South Carolina to Brussels.

  • Can I find deals for flights from South Carolina to Brussels that include hotel bookings?

    Yes. In addition to deals on South Carolina to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Brussels.

  • Can I find deals for business class flights from South Carolina to Brussels?

    Yes. Cheapflights offers flight deals from South Carolina to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Brussels?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Brussels (average of $614). Flying from South Carolina to Brussels in June is currently the most expensive (average of $1,127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Brussels

Discover the top airline that operate flights from South Carolina to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$551Average$1,051FlexibilityNo cancel feeOn-time69%

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