How long is the flight from South Carolina to Brussels?

There are many flights that can get you from South Carolina to Brussels in 10h 17m. Fly via Lufthansa, United Airlines, or Air Canada to get the fastest option. South Carolina and Brussels are separated by a distance of 4269 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Brussels ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels when rainfall is around 1.6 in.

If weather is an important factor for your trip to Brussels, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What are the most popular routes from South Carolina to Brussels?

While some choose either Charleston - Brussels Bruxelles-National or Myrtle Beach Intl - Brussels Bruxelles-National, Charlotte Douglas - Brussels Bruxelles-National is the most popular route from South Carolina to Brussels.

Can I find deals for flights from South Carolina to Brussels that include hotel bookings?

Yes. In addition to deals on South Carolina to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Brussels?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Brussels.

Can I find deals for business class flights from South Carolina to Brussels?

Yes. Cheapflights offers flight deals from South Carolina to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$416+ Flights from South Carolina to Brussels

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Cheap flight deals from South Carolina to Brussels

Cheapest flights from South Carolina to Brussels
Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Tue 12/234:59 pmCHS - BRU

1 stop33h 56mUnited Airlines

Wed 12/3110:10 amBRU - CHS

1 stop15h 08mUnited Airlines

Deal found 12/8

$956

Tue 12/234:59 pmCHS - BRU

2 stops44h 56mLufthansa

Wed 12/3110:10 amBRU - CHS

1 stop15h 08mLufthansa

Deal found 12/8

$967

Tue 12/234:59 pmCHS - BRU

1 stop33h 56mLufthansa

Tue 12/307:30 pmBRU - CHS

2 stops29h 48mLufthansa

Deal found 12/8

$986

Mon 12/86:00 amCHS - BRU

2 stops21h 40mScandinavian Airlines

Mon 12/1510:20 amBRU - CHS

2 stops16h 41mScandinavian Airlines

Deal found 12/7

$1,003

Tue 12/234:59 pmCHS - BRU

1 stop33h 56mUnited Airlines

Mon 12/2911:55 amBRU - CHS

1 stop13h 09mUnited Airlines

Deal found 12/8

$1,026

Tue 12/234:59 pmCHS - BRU

2 stops42h 16mLufthansa

Mon 12/2911:55 amBRU - CHS

1 stop13h 09mLufthansa

Deal found 12/8

$1,037

Thu 12/252:50 pmCHS - BRU

2 stops13h 20mUnited Airlines

Mon 12/2910:00 amBRU - CHS

2 stops58h 09mUnited Airlines

Deal found 12/8

$1,051

Tue 12/234:59 pmCHS - BRU

1 stop33h 56mUnited Airlines

Sun 12/289:40 amBRU - CHS

2 stops30h 55mUnited Airlines

Deal found 12/8

$1,055

Tue 12/234:59 pmCHS - BRU

2 stops44h 56mLufthansa

Sun 12/289:30 amBRU - CHS

2 stops39h 48mLufthansa

Deal found 12/8

$1,062

Thu 12/252:50 pmCHS - BRU

2 stops13h 20mLufthansa

Mon 12/2911:55 amBRU - CHS

1 stop13h 09mLufthansa

Deal found 12/8

$1,064

Wed 12/2411:02 amCLT - BRU

1 stop15h 53mLufthansa

Wed 12/317:00 amBRU - CLT

2 stops22h 59mLufthansa

Deal found 12/6

$1,255

Wed 12/1010:40 amCLT - BRU

2 stops16h 55mAer Lingus

Mon 12/226:55 pmBRU - CLT

2 stops34h 51mAer Lingus

Deal found 12/6

$1,265

Best flights from South Carolina to Brussels
Discover carefully curated flight deals from South Carolina to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 8, 2025.

Thu 1/222:58 pmCHS - BRU

1 stop10h 17mLufthansa

Wed 1/2811:15 amBRU - CHS

1 stop12h 44mLufthansa

Deal found 12/6

$451

Wed 1/281:25 pmMYR - BRU

2 stops17h 50mUnited Airlines

Sun 2/110:00 amBRU - MYR

2 stops32h 41mUnited Airlines

Deal found 12/5

$484

Wed 1/146:00 amCHS - BRU

2 stops19h 50mAir Canada

Sun 1/1810:00 amBRU - CHS

2 stops37h 59mAir Canada

Deal found 12/5

$491

Thu 1/2211:00 amCHS - BRU

2 stops14h 50mMultiple Airlines

Wed 1/2810:10 amBRU - CHS

1 stop15h 52mMultiple Airlines

Deal found 12/6

$502

Wed 1/212:49 pmCAE - BRU

1 stop10h 26mBrussels Airlines

Wed 1/2811:55 amBRU - CAE

1 stop13h 00mBrussels Airlines

Deal found 12/7

$507

Mon 1/264:54 pmCLT - BRU

2 stops15h 36mScandinavian Airlines

Tue 2/1010:20 amBRU - CLT

2 stops17h 52mScandinavian Airlines

Deal found 12/7

$538

Fri 1/302:49 pmCAE - BRU

2 stops16h 26mUnited Airlines

Tue 2/310:00 amBRU - CAE

2 stops34h 14mUnited Airlines

Deal found 12/6

$484

Fri 1/98:00 amCAE - BRU

2 stops23h 15mUnited Airlines

Tue 1/1310:00 amBRU - CAE

2 stops34h 14mUnited Airlines

Deal found 12/5

$484

Wed 1/2110:00 amCLT - BRU

2 stops27h 50mScandinavian Airlines

Fri 1/3010:20 amBRU - CLT

2 stops19h 34mScandinavian Airlines

Deal found 12/5

$548

Tue 1/202:54 pmCLT - BRU

1 stop10h 21mLufthansa

Tue 1/2710:30 amBRU - CLT

2 stops14h 29mLufthansa

Deal found 12/6

$566

Tue 3/102:52 pmCLT - BRU

1 stop11h 23mBrussels Airlines

Wed 3/1811:55 amBRU - CLT

1 stop12h 00mBrussels Airlines

Deal found 12/6

$579

Tue 1/201:25 pmMYR - BRU

1 stop12h 40mUnited Airlines

Tue 1/2710:00 amBRU - MYR

2 stops32h 41mUnited Airlines

Deal found 12/6

$488

Tue 1/2010:00 amCLT - BRU

2 stops27h 50mScandinavian Airlines

Tue 1/2710:20 amBRU - CLT

2 stops18h 46mScandinavian Airlines

Deal found 12/6

$548

Tue 3/312:22 pmHHH - BRU

2 stops19h 13mAmerican Airlines

Thu 5/282:50 pmBRU - HHH

2 stops30h 54mAmerican Airlines

Deal found 12/6

$1,224

Mon 1/262:20 pmCLT - BRU

1 stop11h 45mBrussels Airlines

Tue 2/1011:55 amBRU - CLT

1 stop13h 04mBrussels Airlines

Deal found 12/6

$580

Thu 1/221:13 pmCHS - BRU

1 stop13h 42mUnited Airlines

Thu 1/2910:00 amBRU - CHS

2 stops40h 02mUnited Airlines

Deal found 12/8

$488

Tue 3/1010:15 amCLT - BRU

2 stops23h 15mScandinavian Airlines

Wed 3/1810:20 amBRU - CLT

2 stops17h 23mScandinavian Airlines

Deal found 12/7

$548

Fri 1/236:05 amCHS - BRU

1 stop20h 50mUnited Airlines

Tue 1/2710:00 amBRU - CHS

2 stops34h 48mUnited Airlines

Deal found 12/8

$488

Wed 1/2110:00 amCLT - BRU

3 stops27h 50mScandinavian Airlines

Wed 1/2810:20 amBRU - CLT

2 stops18h 46mScandinavian Airlines

Deal found 12/7

$552

Wed 1/211:13 pmCHS - BRU

1 stop13h 42mUnited Airlines

Tue 1/2710:00 amBRU - CHS

2 stops34h 48mUnited Airlines

Deal found 12/8

$488

Sun 3/294:52 pmCLT - BRU

2 stops34h 48mScandinavian Airlines

Thu 4/23:15 pmBRU - CLT

2 stops37h 14mScandinavian Airlines

Deal found 12/7

$556

Tue 1/207:30 pmCAE - BRU

1 stop29h 45mUnited Airlines

Tue 1/2710:00 amBRU - CAE

2 stops34h 14mUnited Airlines

Deal found 12/6

$488

Tue 1/1310:00 amCLT - BRU

2 stops17h 40mScandinavian Airlines

Tue 1/2710:20 amBRU - CLT

2 stops17h 52mScandinavian Airlines

Deal found 12/6

$578

Thu 1/227:30 pmCAE - BRU

1 stop29h 45mUnited Airlines

Thu 1/2910:00 amBRU - CAE

2 stops54h 17mUnited Airlines

Deal found 12/8

$488

Fri 1/236:30 amCHS - BRU

2 stops24h 45mUnited Airlines

Thu 1/2911:55 amBRU - CHS

1 stop32h 53mUnited Airlines

Deal found 12/8

$504

Wed 1/211:13 pmCHS - BRU

2 stops18h 02mUnited Airlines

Fri 1/3011:15 amBRU - CHS

1 stop12h 44mUnited Airlines

Deal found 12/8

$504

Wed 1/216:00 amCHS - BRU

2 stops20h 55mUnited Airlines

Wed 1/2811:55 amBRU - CHS

1 stop13h 09mUnited Airlines

Deal found 12/8

$504

Fri 1/231:13 pmCHS - BRU

2 stops18h 02mUnited Airlines

Mon 1/2611:55 amBRU - CHS

1 stop13h 09mUnited Airlines

Deal found 12/8

$504

Wed 1/212:37 pmCAE - BRU

2 stops16h 38mUnited Airlines

Wed 1/2811:55 amBRU - CAE

1 stop13h 00mUnited Airlines

Deal found 12/7

$504

Thu 1/221:13 pmCHS - BRU

1 stop13h 42mUnited Airlines

Fri 1/3011:15 amBRU - CHS

1 stop12h 44mUnited Airlines

Deal found 12/8

$507

Last-minute flights from South Carolina to Brussels
Discover last-minute flight deals from South Carolina to Brussels. Data last updated December 8, 2025 and is based on user searches.

Tue 1/201:25 pmMYR - BRU

2 stops17h 50mUnited Airlines

Tue 1/2710:00 amBRU - MYR

2 stops32h 41mUnited Airlines

Deal found 12/6

$484

Wed 1/216:00 amCHS - BRU

2 stops20h 55mUnited Airlines

Wed 1/2811:55 amBRU - CHS

1 stop13h 09mUnited Airlines

Deal found 12/8

$504

Wed 1/212:37 pmCAE - BRU

2 stops16h 38mUnited Airlines

Wed 1/2811:55 amBRU - CAE

1 stop13h 00mUnited Airlines

Deal found 12/7

$504

Thu 1/222:58 pmCHS - BRU

1 stop10h 17mLufthansa

Wed 1/2811:15 amBRU - CHS

1 stop12h 44mLufthansa

Deal found 12/6

$451

Thu 1/222:58 pmCHS - BRU

1 stop10h 17mMultiple Airlines

Thu 1/297:00 amBRU - CHS

2 stops16h 59mMultiple Airlines

Deal found 12/8

$455

Thu 1/222:58 pmCHS - BRU

1 stop10h 17mUnited Airlines

Tue 1/2710:00 amBRU - CHS

2 stops34h 48mUnited Airlines

Deal found 12/8

$488

Thu 1/227:45 pmCHS - BRU

2 stops30h 05mUnited Airlines

Thu 1/2910:00 amBRU - CHS

2 stops40h 02mUnited Airlines

Deal found 12/8

$491

Thu 1/2211:00 amCHS - BRU

2 stops14h 50mMultiple Airlines

Wed 1/2810:10 amBRU - CHS

1 stop15h 52mMultiple Airlines

Deal found 12/6

$502

Thu 1/227:30 pmCAE - BRU

2 stops31h 25mUnited Airlines

Thu 1/2910:00 amBRU - CAE

2 stops54h 17mUnited Airlines

Deal found 12/8

$503

Fri 1/232:58 pmCHS - BRU

1 stop10h 17mLufthansa

Fri 1/306:45 amBRU - CHS

2 stops17h 14mLufthansa

Deal found 12/8

$438

Fri 1/231:13 pmCHS - BRU

1 stop13h 42mLufthansa

Wed 1/287:00 amBRU - CHS

2 stops22h 44mLufthansa

Deal found 12/8

$493

Fri 1/302:49 pmCAE - BRU

2 stops16h 26mUnited Airlines

Tue 2/310:00 amBRU - CAE

2 stops34h 14mUnited Airlines

Deal found 12/6

$484

One-way flights from South Carolina to Brussels
Search for one-way flight options from South Carolina to Brussels. Find affordable one-way fares based on user searches. Data last updated December 8, 2025.

Tue 1/62:58 pmCHS - BRU

2 stops16h 17mUnited Airlines

Deal found 12/6

$416

Tue 1/62:59 pmCHS - BRU

3 stops38h 01mMultiple Airlines

Deal found 12/6

$443

Mon 1/56:20 amCLT - BRU

2 stops24h 55mUnited Airlines

Deal found 12/7

$445

Mon 1/510:38 pmCLT - BRU

3 stops27h 12mMultiple Airlines

Deal found 12/7

$672

Thu 5/72:28 pmMYR - BRU

2 stops16h 32mMultiple Airlines

Deal found 12/7

$2,652

Thu 5/73:25 pmMYR - BRU

1 stop11h 35mUnited Airlines

Deal found 12/7

$3,271

Thu 5/711:25 amMYR - BRU

3 stops19h 50mAir Canada

Deal found 12/7

$3,293

Find flight deals from South Carolina to Brussels

Round-trip from	$451 (Kiwi.com)
One-way from	$416 (United Airlines)

From South Carolina to Brussels

Search Deals

One-way flight from South Carolina to Brussels

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Brussels that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Thu 1/22

2:58 pm-7:15 am

1 stop10h 17m

Brussels Bruxelles-National

Wed 1/28

11:15 am-5:59 pm

1 stop12h 44m

$451

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Wed 1/28

1:25 pm-1:15 pm

2 stops17h 50m

Brussels Bruxelles-National

Sun 2/1

10:00 am-12:41 pm

2 stops32h 41m

$484

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Fri 1/30

2:49 pm-1:15 pm

2 stops16h 26m

Brussels Bruxelles-National

Tue 2/3

10:00 am-2:14 pm

2 stops34h 14m

$484

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Fri 1/9

8:00 am-1:15 pm

2 stops23h 15m

Brussels Bruxelles-National

Tue 1/13

10:00 am-2:14 pm

2 stops34h 14m

$484

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Tue 1/20

1:25 pm-8:05 am

1 stop12h 40m

Brussels Bruxelles-National

Tue 1/27

10:00 am-12:41 pm

2 stops32h 41m

$488

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Thu 1/22

1:13 pm-8:55 am

1 stop13h 42m

Brussels Bruxelles-National

Thu 1/29

10:00 am-8:02 pm

2 stops40h 02m

$488

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 1/23

6:05 am-8:55 am

1 stop20h 50m

Brussels Bruxelles-National

Tue 1/27

10:00 am-2:48 pm

2 stops34h 48m

$488

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 1/21

1:13 pm-8:55 am

1 stop13h 42m

Brussels Bruxelles-National

Tue 1/27

10:00 am-2:48 pm

2 stops34h 48m

$488

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Tue 1/20

7:30 pm-7:15 am

1 stop29h 45m

Brussels Bruxelles-National

Tue 1/27

10:00 am-2:14 pm

2 stops34h 14m

$488

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Thu 1/22

7:30 pm-7:15 am

1 stop29h 45m

Brussels Bruxelles-National

Thu 1/29

10:00 am-10:17 am

2 stops54h 17m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 37 results

Best time to book a flight from South Carolina to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels

What is the cheapest time of day to fly from SC to BRU?

A simple way to save on the total cost of your ticket is to fly from South Carolina to Brussels in the morning. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the evening.

Related info for your journey

How long is the flight from South Carolina to Brussels?
There are many flights that can get you from South Carolina to Brussels in 10h 17m. Fly via Lufthansa, United Airlines, or Air Canada to get the fastest option. South Carolina and Brussels are separated by a distance of 4269 mi. This flight may include one or multiple stops.
What are the most popular routes from South Carolina to Brussels?
While some choose either Charleston - Brussels Bruxelles-National or Myrtle Beach Intl - Brussels Bruxelles-National, Charlotte Douglas - Brussels Bruxelles-National is the most popular route from South Carolina to Brussels.
Can I find deals for flights from South Carolina to Brussels that include hotel bookings?
Yes. In addition to deals on South Carolina to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Brussels?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Brussels.
Can I find deals for business class flights from South Carolina to Brussels?
Yes. Cheapflights offers flight deals from South Carolina to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Carolina to Brussels

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John F Kennedy Intl to Charleroi Brussels flights

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Midway to Bruxelles-National flights

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Boston to Charleroi Brussels flights

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Santa Ana to Bruxelles-National flights

Tampa to Bruxelles-National flights

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Detroit to Bruxelles-National flights

O'Hare Intl to Charleroi Brussels flights

San Jose to Bruxelles-National flights

Love Field to Bruxelles-National flights

Cleveland to Bruxelles-National flights

Dulles Intl to Charleroi Brussels flights

Columbus to Bruxelles-National flights

Indianapolis to Bruxelles-National flights

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Los Angeles to Charleroi Brussels flights

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San Francisco to Charleroi Brussels flights

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Miami to Charleroi Brussels flights

Nashville to Bruxelles-National flights

Complete your trip

Brussels car rentals

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Ostende-Bruges Airport car rentals

Liège Bierset Airport car rentals

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Schaerbeek car rentals

Ixelles car rentals

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Anderlecht car rentals

European Quarter car rentals

Top airline flying from South Carolina to Brussels

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$591	Average$1,043	FlexibilityNo cancel fee	On-time69%

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$416+ Cheap flights from South Carolina to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from South Carolina to Brussels

Cheapest flights from South Carolina to BrusselsExplore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Find flight deals from South Carolina to Brussels

Keep the following information in mind while searching for South Carolina to Brussels flight deals. Data was last updated December 8, 2025.

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Brussels that are best for you.

Best time to book a flight from South Carolina to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels

What is the cheapest time of day to fly from SC to BRU?

Find hourly flight availability from South Carolina to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from South Carolina to Brussels?

What are the most popular routes from South Carolina to Brussels?

Can I find deals for flights from South Carolina to Brussels that include hotel bookings?

How can I find direct flights from South Carolina to Brussels?

Can I find deals for business class flights from South Carolina to Brussels?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Brussels

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from South Carolina to Brussels

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Cheapest flights from South Carolina to Brussels
Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.