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$656+ Cheap flights from Knoxville (TYS) to Brussels

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — BRU
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Knoxville to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$656
(United Airlines)

Popular in

February

Cheapest in

April

Average price

$973
From Knoxville McGhee Tyson to Brussels
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Highest demand for flights based on searches. 17% potential increase in price ($255 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Brussels

Cheapest flights from Knoxville to Brussels
Explore the most affordable flight options available from Knoxville to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:50 amTYS - BRU
1 stop15h 25mUnited Airlines
Sun 11/1610:10 amBRU - TYS
1 stop16h 23mUnited Airlines
Deal found 8/17$656
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:13 pmTYS - BRU
2 stops17h 07mScandinavian Airlines
Wed 10/14:00 pmBRU - TYS
2 stops37h 44mScandinavian Airlines
Deal found 8/18$660
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/44:19 pmTYS - BRU
2 stops17h 01mScandinavian Airlines
Sun 10/58:30 pmBRU - TYS
2 stops33h 16mScandinavian Airlines
Deal found 8/17$690
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:45 amTYS - BRU
1 stop19h 30mUnited Airlines
Wed 10/110:00 amBRU - TYS
2 stops42h 50mUnited Airlines
Deal found 8/18$743
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:45 amTYS - BRU
2 stops20h 55mDelta
Sun 9/2110:45 amBRU - TYS
1 stop16h 41mDelta
Deal found 8/17$756
This KLM deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2310:24 amTYS - BRU
1 stop16h 16mKLM
Wed 10/110:45 amBRU - TYS
1 stop18h 59mKLM
Deal found 8/18$766
This Ovago deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/148:36 pmTYS - BRU
2 stops15h 24mBritish Airways
Sun 9/218:35 pmBRU - TYS
2 stops30h 39mBritish Airways
Deal found 8/17$774
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:45 amTYS - BRU
1 stop19h 30mUnited Airlines
Sun 9/2112:00 pmBRU - TYS
1 stop14h 56mUnited Airlines
Deal found 8/17$796
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/42:30 pmTYS - BRU
1 stop10h 45mUnited Airlines
Sun 10/510:00 amBRU - TYS
2 stops40h 42mUnited Airlines
Deal found 8/18$823
This KLM deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/411:54 amTYS - BRU
1 stop14h 46mKLM
Sun 10/510:45 amBRU - TYS
1 stop15h 17mKLM
Deal found 8/18$846
This Air Canada deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/42:30 pmTYS - BRU
3 stops16h 45mMultiple Airlines
Sun 10/510:00 amBRU - TYS
2 stops18h 50mMultiple Airlines
Deal found 8/17$991

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Knoxville to Brussels that are best for you.

Fly from

Knoxville

Fly to

Brussels

Route

Depart

Return

Price

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 11/12

9:50 am-7:50 am

2 stops16h 00m

Brussels Bruxelles-National

Sun 11/16

10:10 am-8:33 pm

1 stop16h 23m

$656

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 11/12

9:50 am-7:50 am

2 stops16h 00m

Brussels Bruxelles-National

Sun 11/16

10:00 am-11:59 pm

2 stops19h 59m

$656

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 9/23

4:13 pm-3:20 pm

2 stops17h 07m

Brussels Bruxelles-National

Wed 10/1

4:00 pm-11:44 pm

2 stops37h 44m

$660

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 9/4

1:53 pm-7:50 pm

2 stops23h 57m

Brussels Bruxelles-National

Sun 10/5

8:30 pm-11:46 pm

2 stops33h 16m

$690

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Best time to book a flight from Knoxville to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Brussels

What is the cheapest time of day to fly from TYS to BRU?

Find hourly flight availability from Knoxville to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Brussels in the afternoon. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated August 18, 2025.
Peruse reviews from past customers who have flown with United Airlines from Knoxville to Brussels to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,925 reviews

Crew

8.1

Entertainment

7.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,925 reviews
United Airlines
7.4
Good
8,925 reviews

Crew

8.1

Entertainment

7.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Brussels?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Brussels. On average, McGhee Tyson has 0 outbound flights to Brussels per day from 1 airline. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Brussels?

    A quick flight from Knoxville to Brussels can take about 16h. United Airlines provides one of the quickest options available for as low as $656. Knoxville and Brussels are separated by a distance of 4289 mi.

  • What is the cheapest airline to fly from Knoxville to Brussels round-trip?

    Flying on United Airlines is currently your cheapest option to Brussels, with prices starting at $676. This flight start at 43% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Brussels that include hotel bookings?

    Yes. In addition to deals on Knoxville to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Brussels.

  • Can I find deals for business class flights from Knoxville to Brussels?

    Yes. Cheapflights offers flight deals from Knoxville to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Brussels (average of $614). Flying from Knoxville to Brussels in June is currently the most expensive (average of $1,079). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
Knoxville to Bruxelles-National flights
Nashville to Bruxelles-National flights
Blountville to Bruxelles-National flights
Memphis to Bruxelles-National flights

Top airline flying from Knoxville to Brussels

Discover the top airline that operate flights from Knoxville to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$676Average$1,206FlexibilityNo cancel feeOn-time69%

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