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$282+ Cheap flights from Knoxville (TYS) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — BRU
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Knoxville to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$630
(lastminute.com)

One-way from

$282
(Kiwi.com)

Popular in

February

Cheapest in

April

Average price

$1,314
From Knoxville McGhee Tyson to Brussels
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One-way flight from Knoxville McGhee Tyson to Brussels
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Highest demand for flights based on searches. 18% potential increase in price ($267 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($51 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Brussels

Cheapest flights from Knoxville to Brussels
Explore the most affordable flight options available from Knoxville to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This lastminute.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:14 pmTYS - BRU
2 stops32h 26mVirgin Atlantic
Wed 8/2010:45 amBRU - TYS
1 stop12h 34mVirgin Atlantic
Deal found 7/1$630
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:00 amTYS - BRU
1 stop19h 55mUnited Airlines
Sun 11/1611:55 amBRU - TYS
1 stop14h 25mUnited Airlines
Deal found 7/2$655
This Gotogate deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/145:27 pmTYS - BRU
2 stops19h 23mBritish Airways
Wed 8/209:10 pmBRU - TYS
2 stops29h 45mBritish Airways
Deal found 7/1$683
This KLM deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2711:54 amTYS - BRU
2 stops14h 46mKLM
Wed 10/1510:45 amBRU - TYS
1 stop13h 28mKLM
Deal found 7/1$690
This FlightHub deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:53 pmTYS - BRU
2 stops22h 37mScandinavian Airlines
Sun 10/52:55 pmBRU - TYS
2 stops38h 51mScandinavian Airlines
Deal found 7/2$709
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/315:30 amTYS - BRU
1 stop21h 10mDelta
Thu 8/710:45 amBRU - TYS
2 stops19h 14mDelta
Deal found 7/2$855
This Air Canada deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:00 amTYS - BRU
3 stops19h 05mMultiple Airlines
Sun 10/510:00 amBRU - TYS
2 stops18h 50mMultiple Airlines
Deal found 7/3$1,015
This Air Canada deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:55 amTYS - BRU
3 stops16h 10mAir Canada
Sun 10/57:00 amBRU - TYS
3 stops20h 11mAir Canada
Deal found 7/1$1,271
This oojo deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:45 amTYS - BRU
3 stops43h 45mEthiopian Air
Sun 10/59:25 pmBRU - TYS
3 stops47h 20mEthiopian Air
Deal found 7/2$2,638

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Knoxville to Brussels that are best for you.

Fly from

Knoxville

Fly to

Brussels

Route

Depart

Return

Price

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 8/14

6:14 pm-8:40 am

2 stops32h 26m

Brussels Bruxelles-National

Wed 8/20

10:45 am-5:19 pm

1 stop12h 34m

$630

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 11/12

7:00 am-8:55 am

1 stop19h 55m

Brussels Bruxelles-National

Sun 11/16

11:55 am-8:20 pm

1 stop14h 25m

$655

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 8/14

5:27 pm-6:50 pm

2 stops19h 23m

Brussels Bruxelles-National

Wed 8/20

9:10 pm-8:55 pm

2 stops29h 45m

$683

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 8/27

11:54 am-8:40 am

2 stops14h 46m

Brussels Bruxelles-National

Wed 10/15

10:45 am-6:13 pm

1 stop13h 28m

$690

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 9/4

1:53 pm-7:50 pm

2 stops23h 57m

Brussels Bruxelles-National

Sun 10/5

2:55 pm-11:46 pm

2 stops38h 51m

$709

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 7/31

5:30 am-8:40 am

1 stop21h 10m

Brussels Bruxelles-National

Thu 8/7

10:45 am-11:59 pm

2 stops19h 14m

$855

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 9/4

7:00 am-8:05 am

3 stops19h 05m

Brussels Bruxelles-National

Sun 10/5

10:00 am-10:50 pm

2 stops18h 50m

$1,015

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 9/4

9:55 am-8:05 am

3 stops16h 10m

Brussels Bruxelles-National

Sun 10/5

7:00 am-9:11 pm

3 stops20h 11m

$1,271

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Thu 9/4

5:45 am-7:30 am

3 stops43h 45m

Brussels Bruxelles-National

Sun 10/5

9:25 pm-2:45 pm

3 stops47h 20m

$2,638

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 7/27

7:44 pm-9:00 am

3 stops55h 16m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 12 results
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Best time to book a flight from Knoxville to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Brussels

What is the cheapest time of day to fly from TYS to BRU?

Find hourly flight availability from Knoxville to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Brussels in the afternoon. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Delta, KLM, and United Airlines from Knoxville to Brussels to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,367 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Virgin Atlantic
7.4
Good
654 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Scandinavian Airlines
7.3
Good
1,416 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Brussels?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Brussels. On average, McGhee Tyson has 0 outbound flights to Brussels per day from 1 airline. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines flying from Knoxville to Brussels round-trip?

    Flying on Virgin Atlantic is currently your cheapest option to Brussels, with prices starting at $630. Additional round-trip tickets that might be worth considering are offered by United Airlines and British Airways, with the lowest prices starting at $655 and $683, respectively. These flights start at 46% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Brussels that include hotel bookings?

    Yes. In addition to deals on Knoxville to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Brussels.

  • Can I find deals for business class flights from Knoxville to Brussels?

    Yes. Cheapflights offers flight deals from Knoxville to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Brussels (average of $614). Flying from Knoxville to Brussels in June is currently the most expensive (average of $1,079). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Knoxville to Bruxelles-National flights
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Memphis to Bruxelles-National flights

Top airline flying from Knoxville to Brussels

Discover the top airline that operate flights from Knoxville to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$676Average$1,091FlexibilityNo cancel feeOn-time69%

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