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Biloxi

$90+ Cheap flights from Spartanburg, SC to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — MSY
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Spartanburg to Biloxi

Cheapest flights from Spartanburg to Biloxi
Explore the most affordable flight options available from Spartanburg to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:04 pmCLT - GPT
Nonstop2h 04mAmerican Airlines
Sun 12/287:05 amGPT - CLT
Nonstop2h 08mAmerican Airlines
Deal found 12/25$439
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:04 pmCLT - GPT
Nonstop2h 10mAmerican Airlines
Sat 1/37:05 amGPT - CLT
Nonstop2h 08mAmerican Airlines
Deal found 12/27$458
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:53 pmCLT - GPT
1 stop3h 47mDelta
Sun 12/286:00 amGPT - CLT
1 stop3h 53mDelta
Deal found 12/25$459
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:51 pmCLT - GPT
1 stop5h 49mDelta
Sat 1/36:00 amGPT - CLT
1 stop3h 53mDelta
Deal found 12/26$470
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:04 pmCLT - GPT
Nonstop2h 10mAmerican Airlines
Fri 1/27:05 amGPT - CLT
Nonstop2h 08mAmerican Airlines
Deal found 12/25$479
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/282:22 pmCLT - GPT
1 stop5h 48mMultiple Airlines
Tue 12/3010:05 amGPT - CLT
1 stop9h 24mMultiple Airlines
Deal found 12/27$495
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:51 pmCLT - GPT
1 stop5h 49mDelta
Fri 1/26:00 amGPT - CLT
1 stop3h 53mDelta
Deal found 12/25$580
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2710:47 amCLT - GPT
Nonstop2h 14mAmerican Airlines
Sat 12/274:48 pmGPT - CLT
Nonstop2h 02mAmerican Airlines
Deal found 12/26$767
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/264:45 pmCLT - GPT
1 stop5h 52mUnited Airlines
Sun 12/281:57 pmGPT - CLT
2 stops26h 41mUnited Airlines
Deal found 12/25$768

Find flight deals from Spartanburg to Biloxi

Keep the following information in mind while searching for Spartanburg to Biloxi flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$221
(Kiwi.com)

One-way from

$90
(Kiwi.com)

Popular in

September

Cheapest in

May

Average price

$459
Provider with most accurate pricing for Charlotte Douglas-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Gulfport Biloxi Regional flights.
Search Deals
From Spartanburg to Biloxi
Search Deals
One-way flight from Spartanburg to Biloxi
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($83 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Spartanburg to Biloxi that are best for you.

Fly from

Spartanburg

Fly to

Biloxi

Route

Depart

Return

Price

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Sun 2/8

11:12 am-6:40 pm

1 stop8h 28m

Gulfport Biloxi Regional

Sun 2/22

7:20 pm-11:56 pm

2 stops27h 36m

$242

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Wed 3/4

10:31 pm-11:51 pm

Nonstop2h 20m

Gulfport Biloxi Regional

Sat 3/7

4:36 pm-7:35 pm

Nonstop1h 59m

$341

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Sat 2/14

2:51 pm-4:05 pm

Nonstop2h 14m

Gulfport Biloxi Regional

Sat 2/21

4:36 pm-7:35 pm

Nonstop1h 59m

$341

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 2/12

1:17 pm-6:40 pm

1 stop6h 23m

Gulfport Biloxi Regional

Mon 2/16

6:54 pm-11:56 pm

2 stops28h 02m

$360

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Mon 3/2

4:57 pm-9:54 pm

1 stop5h 57m

Gulfport Biloxi Regional

Sat 3/7

3:00 pm-8:38 pm

1 stop4h 38m

$380

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Sat 1/24

6:00 am-9:33 am

1 stop4h 33m

Gulfport Biloxi Regional

Sat 1/31

10:21 am-4:02 pm

1 stop4h 41m

$389

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Fri 2/13

6:59 pm-9:54 pm

1 stop3h 55m

Gulfport Biloxi Regional

Tue 2/17

10:11 am-4:04 pm

1 stop4h 53m

$399

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Fri 5/1

6:56 am-9:18 am

1 stop3h 22m

Gulfport Biloxi Regional

Sun 5/3

2:42 pm-9:42 pm

1 stop6h 00m

$429

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Tue 3/3

10:31 pm-11:51 pm

Nonstop2h 20m

Gulfport Biloxi Regional

Fri 3/6

6:07 am-9:15 am

Nonstop2h 08m

$438

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Fri 1/16

3:43 pm-4:55 pm

Nonstop2h 12m

Gulfport Biloxi Regional

Mon 1/19

6:32 am-9:35 am

Nonstop2h 03m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 19 results
1
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Best time to book a flight from Spartanburg to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Biloxi

What is the cheapest month to book a flight from Spartanburg to Biloxi?

Currently, March is the cheapest month in which you can book a flight from Spartanburg to Biloxi (average of $85). Flying from Spartanburg to Biloxi in December is currently the most expensive (average of $146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to B1L?

Find hourly flight availability from Spartanburg to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 21% on flights from Spartanburg to Biloxi by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Spartanburg to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Biloxi. Price data was last updated on December 27, 2025.

Travelers seeking maximum savings on their Spartanburg to Biloxi flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Spartanburg to Biloxi

Explore weekly flight availability from Spartanburg to Biloxi. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 28, 2025.

The most flights from SB1 to B1L are scheduled on a Monday (7 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (3 on average).

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated December 28, 2025.
Read reviews from past customers who have flown American Airlines from Spartanburg to Biloxi. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Food

6.5

Comfort

7.2

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,072 reviews
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Food

6.5

Comfort

7.2

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Spartanburg to Biloxi flight route?

    The Spartanburg to Biloxi flight path was viewed by 52 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to Biloxi?

    American Airlines and Delta can get you from Spartanburg to Biloxi in just under 2h 20m. Your travel time can differ by up to 3h 37m. Airlines will cover a distance of 577 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Spartanburg to Biloxi?

    Consider Spirit Airlines (90%), British Airways (89%) or American Airlines (83%) when booking your flight. These represent the most reliable airlines when flying from Spartanburg to Biloxi.

  • What are the cheapest flights from Spartanburg to Biloxi?

    While on average a flight from Spartanburg to Biloxi is generally $428, our data shows the cheapest flight currently is $185. When looking at the most popular route, (Charlotte Douglas - Gulfport Biloxi Regional), you can expect to pay $221 for that flight.

  • Can I find deals for flights from Spartanburg to Biloxi that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Biloxi.

  • Can I find deals for business class flights from Spartanburg to Biloxi?

    Yes. Cheapflights offers flight deals from Spartanburg to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Biloxi?

    Currently, March is the cheapest month in which you can book a flight from Spartanburg to Biloxi (average of $85). Flying from Spartanburg to Biloxi in December is currently the most expensive (average of $146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 5 airlines flying from Spartanburg to Biloxi

Discover the top 5 airlines that operate flights from Spartanburg to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$58Average$117FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$94Average$201FlexibilityNo cancel feeOn-time65%
DeltaCheapest$163Average$400FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$182Average$407FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$235Average$367FlexibilityNo cancel feeOn-time63%

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