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Biloxi

$106+ Cheap flights from Spartanburg, SC to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — MSY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Spartanburg to Biloxi

Keep the following information in mind while searching for Spartanburg to Biloxi flight deals. Data was last updated September 16, 2025.

Round-trip from

$241
(Kiwi.com)

One-way from

$106
(Kiwi.com)

Popular in

September

Cheapest in

May

Average price

$523
From Spartanburg to Biloxi
Search Deals
One-way flight from Spartanburg to Biloxi
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Highest demand for flights based on searches. 6% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Spartanburg to Biloxi

Cheapest flights from Spartanburg to Biloxi
Explore the most affordable flight options available from Spartanburg to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:45 amCLT - GPT
2 stops28h 14mMultiple Airlines
Sun 10/267:55 pmGPT - CLT
1 stop10h 52mMultiple Airlines
Deal found 9/15$241
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:30 amCLT - GPT
1 stop4h 49mDelta
Fri 10/106:05 pmGPT - CLT
1 stop4h 45mDelta
Deal found 9/15$297
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:57 amCLT - GPT
1 stop10h 18mMultiple Airlines
Mon 11/106:51 pmGPT - CLT
2 stops20h 20mMultiple Airlines
Deal found 9/16$325
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:30 amCLT - GPT
1 stop4h 49mDelta
Sat 10/43:45 pmGPT - CLT
1 stop3h 40mDelta
Deal found 9/15$357
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:20 pmCLT - GPT
Nonstop2h 10mAmerican Airlines
Sat 10/1812:42 pmGPT - CLT
Nonstop2h 00mAmerican Airlines
Deal found 9/15$361
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:30 amCLT - GPT
1 stop4h 49mDelta
Sun 10/56:08 amGPT - CLT
1 stop5h 54mDelta
Deal found 9/15$377
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:14 pmCLT - GPT
Nonstop2h 01mAmerican Airlines
Mon 11/31:45 pmGPT - CLT
Nonstop2h 00mAmerican Airlines
Deal found 9/14$381
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:05 pmCLT - GPT
1 stop8h 10mMultiple Airlines
Mon 10/136:51 pmGPT - CLT
2 stops27h 37mMultiple Airlines
Deal found 9/16$395
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:40 pmCLT - GPT
1 stop3h 59mDelta
Wed 10/16:08 amGPT - CLT
1 stop5h 54mDelta
Deal found 9/15$396
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:49 pmCLT - GPT
Nonstop2h 10mAmerican Airlines
Sun 10/266:14 amGPT - CLT
Nonstop2h 06mAmerican Airlines
Deal found 9/14$401

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Spartanburg to Biloxi that are best for you.

Fly from

Spartanburg

Fly to

Biloxi

Route

Depart

Return

Price

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 10/23

5:45 am-8:59 am

2 stops28h 14m

Gulfport Biloxi Regional

Sun 10/26

7:55 pm-7:47 am

1 stop10h 52m

$241

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Tue 9/30

5:30 am-9:19 am

1 stop4h 49m

Gulfport Biloxi Regional

Sat 10/4

3:45 pm-8:25 pm

1 stop3h 40m

$357

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Wed 3/4

8:20 pm-9:36 pm

Nonstop2h 16m

Gulfport Biloxi Regional

Sat 3/7

6:52 pm-9:50 pm

Nonstop1h 58m

$361

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Fri 10/3

5:30 am-9:19 am

1 stop4h 49m

Gulfport Biloxi Regional

Sun 10/5

6:08 am-1:02 pm

1 stop5h 54m

$377

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Fri 10/31

4:14 pm-5:15 pm

Nonstop2h 01m

Gulfport Biloxi Regional

Mon 11/3

1:45 pm-4:45 pm

Nonstop2h 00m

$381

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Sat 9/27

6:40 pm-9:39 pm

1 stop3h 59m

Gulfport Biloxi Regional

Wed 10/1

6:08 am-1:02 pm

1 stop5h 54m

$396

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Wed 3/4

10:07 am-1:37 pm

1 stop4h 30m

Gulfport Biloxi Regional

Sat 3/7

10:30 am-4:03 pm

1 stop4h 33m

$401

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 10/23

4:40 pm-5:48 pm

Nonstop2h 08m

Gulfport Biloxi Regional

Sun 10/26

6:14 am-9:20 am

Nonstop2h 06m

$403

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 10/23

6:45 am-9:16 am

1 stop3h 31m

Gulfport Biloxi Regional

Sun 10/26

6:00 am-11:00 am

1 stop4h 00m

$421

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Sun 12/14

2:16 pm-8:59 am

1 stop19h 43m

$106

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 17 results
1
2

Best time to book a flight from Spartanburg to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Biloxi

What is the cheapest month to book a flight from Spartanburg to Biloxi?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to Biloxi (average of $256). Flying from Spartanburg to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to B1L?

Find hourly flight availability from Spartanburg to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Spartanburg to Biloxi as you normally would.

What is the cheapest day to fly from Spartanburg to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Biloxi. Price data was last updated on October 20, 2024.

Travelers seeking maximum savings on their Spartanburg to Biloxi flight should consider departing on Friday afternoons when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Spartanburg to Biloxi

Explore weekly flight availability from Spartanburg to Biloxi. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from SB1 to B1L are scheduled on a Thursday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (5 on average).

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown American Airlines from Spartanburg to Biloxi. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Entertainment

6.9

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Entertainment

6.9

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Spartanburg to Biloxi flight route?

    The Spartanburg to Biloxi flight path was viewed by 56 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Spartanburg to Biloxi?

    Delta and American Airlines can get you from Spartanburg to Biloxi in just under 2h 16m. Your travel time can differ by up to 2h 33m. Airlines will cover a distance of 577 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Spartanburg to Biloxi?

    Consider PSA Airlines (100%), American Airlines (77%) or Spirit Airlines (70%) when booking your flight. These represent the most reliable airlines when flying from Spartanburg to Biloxi.

  • What are the cheapest flights from Spartanburg to Biloxi?

    While on average a flight from Spartanburg to Biloxi is generally $408, our data shows the cheapest flight currently is $56. When looking at the most popular route, (Charlotte Douglas - Gulfport Biloxi Regional), you can expect to pay $297 for that flight.

  • Can I find deals for flights from Spartanburg to Biloxi that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Biloxi.

  • Can I find deals for business class flights from Spartanburg to Biloxi?

    Yes. Cheapflights offers flight deals from Spartanburg to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to Biloxi (average of $256). Flying from Spartanburg to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Spartanburg to Biloxi

Discover the top 5 airlines that operate flights from Spartanburg to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$87Average$190FlexibilityNo cancel feeOn-time65%
FrontierCheapest$95Average$162FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$188Average$436FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$395FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$239Average$381FlexibilityNo cancel feeOn-time63%

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