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Biloxi

$90+ Cheap flights from South Carolina to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MSY
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from South Carolina to Biloxi

Cheapest flights from South Carolina to Biloxi
Explore the most affordable flight options available from South Carolina to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:12 am
CLT
-
GPT
1 stop8h 28m
Multiple Airlines
Sun 3/17:20 pm
GPT
-
CLT
1 stop10h 29m
Multiple Airlines
Deal found 1/26$217
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:12 am
CLT
-
GPT
1 stop8h 28m
Multiple Airlines
Thu 3/57:20 pm
GPT
-
CLT
1 stop11h 43m
Multiple Airlines
Deal found 1/27$233
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:12 am
CLT
-
GPT
1 stop8h 28m
Multiple Airlines
Sun 3/87:20 pm
GPT
-
CLT
1 stop11h 38m
Multiple Airlines
Deal found 1/26$234
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:12 am
CLT
-
GPT
1 stop8h 28m
Multiple Airlines
Sun 5/37:20 pm
GPT
-
CLT
1 stop13h 57m
Multiple Airlines
Deal found 1/27$239
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/58:59 pm
CHS
-
GPT
1 stop13h 01m
Breeze Airways
Sun 2/87:20 pm
GPT
-
CHS
1 stop12h 23m
Breeze Airways
Deal found 1/26$257
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:03 pm
CHS
-
GPT
1 stop5h 54m
American Airlines
Mon 3/94:29 pm
GPT
-
CHS
1 stop5h 32m
American Airlines
Deal found 1/27$269
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:19 pm
MYR
-
GPT
1 stop4h 22m
American Airlines
Sat 2/144:29 pm
GPT
-
MYR
1 stop6h 26m
American Airlines
Deal found 1/26$279
This Breeze Airways deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:59 pm
CHS
-
GPT
1 stop13h 01m
Breeze Airways
Fri 2/206:54 pm
GPT
-
CHS
1 stop15h 41m
Breeze Airways
Deal found 1/27$292
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/51:46 pm
CLT
-
GPT
1 stop5h 54m
Multiple Airlines
Thu 4/97:20 pm
GPT
-
CLT
1 stop13h 17m
Multiple Airlines
Deal found 1/26$309
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/78:16 am
GSP
-
GPT
1 stop6h 03m
American Airlines
Wed 2/116:32 am
GPT
-
GSP
1 stop3h 47m
American Airlines
Deal found 1/27$309
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/58:59 pm
CHS
-
GPT
1 stop13h 01m
Multiple Airlines
Sun 2/87:20 pm
GPT
-
CHS
2 stops21h 19m
Multiple Airlines
Deal found 1/26$310
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:30 am
CHS
-
GPT
1 stop3h 54m
Delta
Thu 3/265:57 pm
GPT
-
CHS
1 stop5h 19m
Delta
Deal found 1/26$311

Find flight deals from South Carolina to Biloxi

Keep the following information in mind while searching for South Carolina to Biloxi flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(Kiwi.com)

One-way from

$90
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$406
Provider with most accurate pricing for Myrtle Beach Intl-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Gulfport Biloxi Regional flights.
Search Deals
From South Carolina to Biloxi
Search Deals
One-way flight from South Carolina to Biloxi
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from South Carolina to Biloxi that are best for you.

Fly from

South Carolina

Fly to

Biloxi

Route

Depart

Return

Price

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Mon 3/2

7:03 pm-11:57 pm

1 stop5h 54m

Gulfport Biloxi Regional

Mon 3/9

4:29 pm-11:01 pm

1 stop5h 32m

$269

Myrtle BeachGulfport

MYR - GPT

MYRGPT

Myrtle Beach Intl

Tue 2/10

7:19 pm-10:41 pm

1 stop4h 22m

Gulfport Biloxi Regional

Sat 2/14

4:29 pm-11:55 pm

1 stop6h 26m

$279

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 4/30

7:49 pm-9:00 am

2 stops14h 11m

Gulfport Biloxi Regional

Sun 5/3

7:20 pm-10:30 am

1 stop14h 10m

$288

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Thu 2/19

8:59 pm-9:00 am

1 stop13h 01m

Gulfport Biloxi Regional

Fri 2/20

6:54 pm-11:35 am

1 stop15h 41m

$292

GreenvilleGulfport

GSP - GPT

GSPGPT

Greenville

Sat 2/7

8:16 am-1:19 pm

1 stop6h 03m

Gulfport Biloxi Regional

Wed 2/11

6:32 am-11:19 am

1 stop3h 47m

$309

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Tue 2/17

6:30 am-9:24 am

1 stop3h 54m

Gulfport Biloxi Regional

Thu 3/26

5:57 pm-12:16 am

1 stop5h 19m

$311

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Fri 4/24

5:20 am-9:24 am

1 stop5h 04m

Gulfport Biloxi Regional

Tue 5/26

6:00 pm-11:56 pm

1 stop4h 56m

$319

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Tue 2/24

6:30 am-9:24 am

1 stop3h 54m

Gulfport Biloxi Regional

Tue 3/3

6:00 am-11:56 am

1 stop4h 56m

$319

ColumbiaGulfport

CAE - GPT

CAEGPT

Columbia Metropolitan

Sat 2/7

6:50 am-9:33 am

1 stop3h 43m

Gulfport Biloxi Regional

Tue 2/10

6:05 am-11:58 am

1 stop4h 53m

$348

ColumbiaGulfport

CAE - GPT

CAEGPT

Columbia Metropolitan

Thu 3/5

5:35 am-9:24 am

1 stop4h 49m

Gulfport Biloxi Regional

Sun 3/8

5:57 pm-11:48 pm

1 stop4h 51m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 44 results
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Best time to book a flight from South Carolina to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Biloxi

What is the cheapest month to book a flight from South Carolina to Biloxi?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Biloxi (average of $76). Flying from South Carolina to Biloxi in April is currently the most expensive (average of $162). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to B1L?

Find hourly flight availability from South Carolina to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 51% on flights from South Carolina to Biloxi by exploring options for tickets in the morning.

What is the cheapest day to fly from South Carolina to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Biloxi. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their South Carolina to Biloxi flight should consider departing on Tuesday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Biloxi flight route?

    This flight path from South Carolina to Biloxi was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Biloxi?

    Departing from South Carolina to Biloxi will take you 3h 54m. The distance from South Carolina to Biloxi is about 558 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Biloxi?

    While some choose either Charleston - Gulfport Biloxi Regional or Columbia Metropolitan - Gulfport Biloxi Regional, Charlotte Douglas - Gulfport Biloxi Regional is the most popular route from South Carolina to Biloxi.

  • What are the cheapest flights from South Carolina to Biloxi?

    While on average a flight from South Carolina to Biloxi is generally $166, our data shows the cheapest flight currently is $69. When looking at the most popular route, (Charlotte Douglas - Gulfport Biloxi Regional), you can expect to pay $233 for that flight.

  • Can I find deals for flights from South Carolina to Biloxi that include hotel bookings?

    Yes. In addition to deals on South Carolina to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Biloxi.

  • Can I find deals for business class flights from South Carolina to Biloxi?

    Yes. Cheapflights offers flight deals from South Carolina to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Biloxi?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Biloxi (average of $76). Flying from South Carolina to Biloxi in April is currently the most expensive (average of $162). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Biloxi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Biloxi

Discover the top 5 airlines that operate flights from South Carolina to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$98Average$177FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$119Average$202FlexibilityNo cancel feeOn-time65%
DeltaCheapest$158Average$424FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$230Average$381FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$232Average$456FlexibilityNo cancel feeOn-time63%

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