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Biloxi

$119+ Cheap flights from South Carolina to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MSY
Oct 22 — Oct 291
Wed 10/22
Wed 10/29
1 adult, Economy
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Cheap flight deals from South Carolina to Biloxi

Keep the following information in mind while searching for South Carolina to Biloxi flight deals. Data was last updated September 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$162
(Kiwi.com)

One-way from

$119
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$401
Provider with most accurate pricing for Myrtle Beach Intl-Gulfport Biloxi Regional flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Gulfport Biloxi Regional flights.
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From South Carolina to Biloxi
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One-way flight from South Carolina to Biloxi
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Highest demand for flights based on searches. 18% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from South Carolina to Biloxi

Cheapest flights from South Carolina to Biloxi
Explore the most affordable flight options available from South Carolina to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:59 pmCHS - GPT
1 stop5h 16mBreeze Airways
Mon 10/276:51 pmGPT - CHS
1 stop13h 37mBreeze Airways
Deal found 9/22$158
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:45 amSAV - GPT
1 stop6h 38mAmerican Airlines
Mon 11/245:26 pmGPT - SAV
1 stop4h 53mAmerican Airlines
Deal found 9/21$229
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:11 amCHS - GPT
2 stops23h 48mMultiple Airlines
Mon 10/276:51 pmGPT - CHS
1 stop13h 37mMultiple Airlines
Deal found 9/22$239
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2610:05 pmCLT - GPT
1 stop11h 54mMultiple Airlines
Thu 10/307:55 pmGPT - CLT
1 stop10h 52mMultiple Airlines
Deal found 9/22$244
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1910:05 pmCLT - GPT
1 stop11h 54mMultiple Airlines
Sun 10/267:55 pmGPT - CLT
1 stop10h 52mMultiple Airlines
Deal found 9/21$255
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/79:30 amCHS - GPT
1 stop5h 16mDelta
Sat 10/113:45 pmGPT - CHS
1 stop4h 06mDelta
Deal found 9/22$259
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:09 pmCLT - GPT
2 stops18h 50mMultiple Airlines
Sun 10/127:55 pmGPT - CLT
1 stop10h 52mMultiple Airlines
Deal found 9/21$268
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/55:45 amCLT - GPT
2 stops28h 14mMultiple Airlines
Thu 10/97:55 pmGPT - CLT
1 stop11h 05mMultiple Airlines
Deal found 9/20$269
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/55:45 amCLT - GPT
2 stops28h 14mMultiple Airlines
Sun 10/127:55 pmGPT - CLT
1 stop10h 52mMultiple Airlines
Deal found 9/21$273
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:34 pmCHS - GPT
1 stop6h 12mAmerican Airlines
Sun 10/196:18 pmGPT - CHS
1 stop4h 47mAmerican Airlines
Deal found 9/20$279
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:41 pmCHS - GPT
1 stop4h 05mAmerican Airlines
Tue 10/286:15 amGPT - CHS
1 stop4h 20mAmerican Airlines
Deal found 9/21$294
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/84:00 pmCLT - GPT
1 stop28h 15mMultiple Airlines
Sun 10/127:55 pmGPT - CLT
1 stop10h 52mMultiple Airlines
Deal found 9/21$300

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from South Carolina to Biloxi that are best for you.

Fly from

South Carolina

Fly to

Biloxi

Route

Depart

Return

Price

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Thu 10/23

2:59 pm-7:15 pm

1 stop5h 16m

Gulfport Biloxi Regional

Mon 10/27

6:51 pm-9:28 am

1 stop13h 37m

$158

SavannahGulfport

SAV - GPT

SAVGPT

Savannah/Hilton Head

Thu 11/20

6:45 am-12:23 pm

1 stop6h 38m

Gulfport Biloxi Regional

Mon 11/24

5:26 pm-11:19 pm

1 stop4h 53m

$229

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Thu 10/23

10:11 am-8:59 am

2 stops23h 48m

Gulfport Biloxi Regional

Mon 10/27

6:51 pm-9:28 am

1 stop13h 37m

$239

ColumbiaGulfport

CAE - GPT

CAEGPT

Columbia Metropolitan

Sat 2/21

10:10 am-1:37 pm

1 stop4h 27m

Gulfport Biloxi Regional

Wed 2/25

6:00 am-12:29 pm

1 stop5h 29m

$249

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Tue 10/7

9:30 am-1:46 pm

1 stop5h 16m

Gulfport Biloxi Regional

Sat 10/11

3:45 pm-8:51 pm

1 stop4h 06m

$259

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 10/9

3:09 pm-8:59 am

2 stops18h 50m

Gulfport Biloxi Regional

Sun 10/12

7:55 pm-7:47 am

1 stop10h 52m

$268

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Sun 10/5

5:45 am-8:59 am

2 stops28h 14m

Gulfport Biloxi Regional

Sun 10/12

7:55 pm-7:47 am

1 stop10h 52m

$273

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Tue 10/14

5:34 pm-10:46 pm

1 stop6h 12m

Gulfport Biloxi Regional

Sun 10/19

6:18 pm-12:05 am

1 stop4h 47m

$279

CharlestonGulfport

CHS - GPT

CHSGPT

Charleston

Fri 10/24

7:41 pm-10:46 pm

1 stop4h 05m

Gulfport Biloxi Regional

Tue 10/28

6:15 am-11:35 am

1 stop4h 20m

$294

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Wed 10/8

4:00 pm-7:15 pm

1 stop28h 15m

Gulfport Biloxi Regional

Sun 10/12

7:55 pm-7:47 am

1 stop10h 52m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/20

Showing 1-10 of 49 results
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Best time to book a flight from South Carolina to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Biloxi

What is the cheapest month to book a flight from South Carolina to Biloxi?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Biloxi (average of $256). Flying from South Carolina to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to B1L?

Find hourly flight availability from South Carolina to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2025.

When flying from South Carolina to Biloxi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Biloxi flight route?

    This flight path from South Carolina to Biloxi was viewed by 4 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Biloxi?

    Departing from South Carolina to Biloxi will take you 4h 27m. The distance from South Carolina to Biloxi is about 524 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Biloxi one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $149. Breeze Airways flights start at $190 while deals on Delta start at $194 one-way.

  • What are the most popular routes from South Carolina to Biloxi?

    While some choose either Columbia Metropolitan - Gulfport Biloxi Regional or Charleston - Gulfport Biloxi Regional, Charlotte Douglas - Gulfport Biloxi Regional is the most popular route from South Carolina to Biloxi.

  • What are the cheapest flights from South Carolina to Biloxi?

    While on average a flight from South Carolina to Biloxi is generally $184, our data shows the cheapest flight currently is $59. When looking at the most popular route, (Charlotte Douglas - Gulfport Biloxi Regional), you can expect to pay $255 for that flight.

  • Can I find deals for flights from South Carolina to Biloxi that include hotel bookings?

    Yes. In addition to deals on South Carolina to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Biloxi.

  • Can I find deals for business class flights from South Carolina to Biloxi?

    Yes. Cheapflights offers flight deals from South Carolina to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Biloxi (average of $256). Flying from South Carolina to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Biloxi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Biloxi

Discover the top 5 airlines that operate flights from South Carolina to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$98Average$177FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$141Average$296FlexibilityNo cancel feeOn-time65%
DeltaCheapest$188Average$416FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$231Average$439FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$232Average$426FlexibilityNo cancel feeOn-time71%

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