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Biloxi

$90+ Cheap flights from South Carolina to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MSY
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from South Carolina to Biloxi

Cheapest flights from South Carolina to Biloxi
Explore the most affordable flight options available from South Carolina to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:33 amGSP - GPT
1 stop8h 37mBreeze Airways
Mon 12/296:51 pmGPT - GSP
1 stop24h 49mBreeze Airways
Deal found 12/12$272
This Breeze Airways deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:17 pmGSP - GPT
1 stop16h 42mBreeze Airways
Mon 12/296:51 pmGPT - GSP
1 stop24h 49mBreeze Airways
Deal found 12/14$288
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 pmGSP - GPT
1 stop4h 55mDelta
Wed 1/710:21 amGPT - GSP
1 stop5h 02mDelta
Deal found 12/14$319
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:04 pmCLT - GPT
Nonstop2h 10mAmerican Airlines
Sat 1/34:48 pmGPT - CLT
Nonstop2h 02mAmerican Airlines
Deal found 12/15$369
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:47 amCLT - GPT
Nonstop2h 14mAmerican Airlines
Sat 1/105:34 pmGPT - CLT
Nonstop2h 10mAmerican Airlines
Deal found 12/15$371
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:15 pmCLT - GPT
1 stop4h 30mDelta
Sat 1/106:05 amGPT - CLT
1 stop5h 55mDelta
Deal found 12/15$389
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:44 amSAV - GPT
1 stop6h 17mAmerican Airlines
Thu 1/14:48 pmGPT - SAV
1 stop6h 25mAmerican Airlines
Deal found 12/13$408
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:12 amGSP - GPT
1 stop6h 02mAmerican Airlines
Wed 1/71:45 pmGPT - GSP
2 stops9h 12mAmerican Airlines
Deal found 12/14$408
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/282:22 pmCLT - GPT
1 stop5h 48mMultiple Airlines
Thu 1/17:50 pmGPT - CLT
1 stop23h 49mMultiple Airlines
Deal found 12/12$416
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:55 pmCLT - GPT
Nonstop2h 17mAmerican Airlines
Thu 1/14:48 pmGPT - CLT
Nonstop2h 02mAmerican Airlines
Deal found 12/13$418
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:59 pmCHS - GPT
1 stop5h 16mBreeze Airways
Fri 12/196:51 pmGPT - CHS
1 stop19h 37mBreeze Airways
Deal found 12/14$426
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:33 pmCHS - GPT
1 stop18h 52mBreeze Airways
Fri 1/26:51 pmGPT - CHS
1 stop19h 37mBreeze Airways
Deal found 12/14$443

Find flight deals from South Carolina to Biloxi

Keep the following information in mind while searching for South Carolina to Biloxi flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$215
(United Airlines)

One-way from

$90
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$716
Provider with most accurate pricing for Myrtle Beach Intl-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Gulfport Biloxi Regional flights.
Search Deals
From South Carolina to Biloxi
Search Deals
One-way flight from South Carolina to Biloxi
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($76 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from South Carolina to Biloxi that are best for you.

Fly from

South Carolina

Fly to

Biloxi

Route

Depart

Return

Price

SavannahGulfport

SAV - GPT

SAVGPT

Savannah/Hilton Head

Thu 1/8

11:43 am-3:58 pm

1 stop5h 15m

Gulfport Biloxi Regional

Mon 1/12

1:57 pm-9:45 pm

1 stop6h 48m

$215

SavannahGulfport

SAV - GPT

SAVGPT

Savannah/Hilton Head

Thu 1/8

5:21 pm-10:41 pm

1 stop6h 20m

Gulfport Biloxi Regional

Wed 1/14

6:32 am-12:07 pm

1 stop4h 35m

$216

SavannahGulfport

SAV - GPT

SAVGPT

Savannah/Hilton Head

Thu 1/8

7:10 pm-10:41 pm

1 stop4h 31m

Gulfport Biloxi Regional

Mon 1/12

6:32 am-7:40 pm

2 stops12h 08m

$220

ColumbiaGulfport

CAE - GPT

CAEGPT

Columbia Metropolitan

Sat 3/21

5:30 am-9:19 am

1 stop4h 49m

Gulfport Biloxi Regional

Tue 3/24

2:44 pm-8:45 pm

1 stop5h 01m

$269

GreenvilleGulfport

GSP - GPT

GSPGPT

Greenville

Fri 1/23

5:40 am-9:33 am

1 stop4h 53m

Gulfport Biloxi Regional

Tue 1/27

6:05 am-11:03 am

1 stop3h 58m

$269

GreenvilleGulfport

GSP - GPT

GSPGPT

Greenville

Thu 12/25

11:33 am-7:10 pm

1 stop8h 37m

Gulfport Biloxi Regional

Mon 12/29

6:51 pm-8:40 pm

1 stop24h 49m

$272

GreenvilleGulfport

GSP - GPT

GSPGPT

Greenville

Fri 1/23

12:09 pm-4:55 pm

1 stop5h 46m

Gulfport Biloxi Regional

Tue 1/27

6:32 am-6:26 pm

2 stops10h 54m

$274

SavannahGulfport

SAV - GPT

SAVGPT

Savannah/Hilton Head

Sat 1/10

3:28 pm-7:48 pm

1 stop5h 20m

Gulfport Biloxi Regional

Wed 1/14

1:57 pm-9:45 pm

1 stop6h 48m

$275

GreenvilleGulfport

GSP - GPT

GSPGPT

Greenville

Wed 3/11

5:40 am-9:19 am

1 stop4h 39m

Gulfport Biloxi Regional

Wed 3/18

6:02 pm-11:52 pm

1 stop4h 50m

$289

GreenvilleGulfport

GSP - GPT

GSPGPT

Greenville

Mon 3/9

7:59 pm-10:19 pm

1 stop3h 20m

Gulfport Biloxi Regional

Mon 3/16

6:02 pm-11:52 pm

1 stop4h 50m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 43 results
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Best time to book a flight from South Carolina to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Biloxi

What is the cheapest month to book a flight from South Carolina to Biloxi?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Biloxi (average of $75). Flying from South Carolina to Biloxi in April is currently the most expensive (average of $157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to B1L?

Find hourly flight availability from South Carolina to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 29% on flights from South Carolina to Biloxi by exploring options for tickets in the afternoon.

What is the cheapest day to fly from South Carolina to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Biloxi flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Biloxi flight route?

    This flight path from South Carolina to Biloxi was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Biloxi?

    Departing from South Carolina to Biloxi will take you 4h 49m. The distance from South Carolina to Biloxi is about 524 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Biloxi?

    While some choose either Greenville - Gulfport Biloxi Regional or Charleston - Gulfport Biloxi Regional, Charlotte Douglas - Gulfport Biloxi Regional is the most popular route from South Carolina to Biloxi.

  • What are the cheapest flights from South Carolina to Biloxi?

    While on average a flight from South Carolina to Biloxi is generally $232, our data shows the cheapest flight currently is $89. When looking at the most popular route, (Charlotte Douglas - Gulfport Biloxi Regional), you can expect to pay $265 for that flight.

  • Can I find deals for flights from South Carolina to Biloxi that include hotel bookings?

    Yes. In addition to deals on South Carolina to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Biloxi.

  • Can I find deals for business class flights from South Carolina to Biloxi?

    Yes. Cheapflights offers flight deals from South Carolina to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Biloxi?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Biloxi (average of $75). Flying from South Carolina to Biloxi in April is currently the most expensive (average of $157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Biloxi

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Top 5 airlines flying from South Carolina to Biloxi

Discover the top 5 airlines that operate flights from South Carolina to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$98Average$181FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$141Average$176FlexibilityNo cancel feeOn-time65%
DeltaCheapest$196Average$427FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$230Average$395FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$232Average$448FlexibilityNo cancel feeOn-time63%

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