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Biloxi

$274+ Cheap flights from Louisville (SDF) to Biloxi, MS

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — MSY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Louisville to Biloxi

Cheapest flights from Louisville to Biloxi
Explore the most affordable flight options available from Louisville to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:51 pmSDF - GPT
1 stop3h 49mDelta
Mon 12/296:00 amGPT - SDF
1 stop6h 35mDelta
Deal found 10/28$274
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:35 amSDF - GPT
1 stop6h 33mDelta
Tue 11/182:53 pmGPT - SDF
1 stop5h 38mDelta
Deal found 10/29$279
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:26 pmSDF - GPT
1 stop8h 10mAmerican Airlines
Tue 11/181:45 pmGPT - SDF
2 stops8h 10mAmerican Airlines
Deal found 10/29$284
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:10 amSDF - GPT
1 stop7h 10mUnited Airlines
Sun 11/21:57 pmGPT - SDF
1 stop7h 00mUnited Airlines
Deal found 10/27$349
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:24 pmSDF - GPT
1 stop5h 48mAmerican Airlines
Mon 12/297:05 amGPT - SDF
2 stops9h 14mAmerican Airlines
Deal found 10/28$474
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:37 amSDF - GPT
1 stop4h 31mDelta
Sun 11/306:03 pmGPT - SDF
1 stop5h 03mDelta
Deal found 10/28$514
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:13 amSDF - GPT
1 stop6h 24mAmerican Airlines
Wed 11/51:45 pmGPT - SDF
1 stop6h 54mAmerican Airlines
Deal found 10/29$667
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:41 amSDF - GPT
1 stop5h 17mDelta
Thu 11/63:45 pmGPT - SDF
1 stop5h 49mDelta
Deal found 10/29$673

Cheap flight deals from Louisville to Biloxi

Keep the following information in mind while searching for Louisville to Biloxi flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(Delta)

Popular in

March

Cheapest in

January

Average price

$418
Provider with most accurate pricing for Louisville Intl-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Gulfport Biloxi Regional flights.
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From Louisville Intl to Biloxi
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Louisville to Biloxi that are best for you.

Fly from

Louisville

Fly to

Biloxi

Route

Depart

Return

Price

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 12/22

6:51 pm-9:40 pm

1 stop3h 49m

Gulfport Biloxi Regional

Mon 12/29

6:00 am-1:35 pm

1 stop6h 35m

$274

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 11/14

8:35 am-2:08 pm

1 stop6h 33m

Gulfport Biloxi Regional

Tue 11/18

2:53 pm-9:31 pm

1 stop5h 38m

$279

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 11/14

4:26 pm-11:36 pm

1 stop8h 10m

Gulfport Biloxi Regional

Tue 11/18

1:45 pm-10:55 pm

2 stops8h 10m

$284

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 1/30

5:35 am-3:58 pm

2 stops11h 23m

Gulfport Biloxi Regional

Sun 2/8

1:57 pm-9:59 pm

1 stop7h 02m

$369

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 12/22

7:24 pm-12:12 am

1 stop5h 48m

Gulfport Biloxi Regional

Mon 12/29

7:05 am-5:19 pm

2 stops9h 14m

$474

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Tue 11/25

10:37 am-2:08 pm

1 stop4h 31m

Gulfport Biloxi Regional

Sun 11/30

6:03 pm-12:06 am

1 stop5h 03m

$514

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Tue 11/25

6:00 am-12:23 pm

2 stops7h 23m

Gulfport Biloxi Regional

Sun 11/30

4:54 pm-12:22 am

1 stop6h 28m

$694

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Best time to book a flight from Louisville to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Biloxi

What is the cheapest month to book a flight from Louisville to Biloxi?

Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $82). Flying from Louisville to Biloxi in February is currently the most expensive (average of $144). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to B1L?

Find hourly flight availability from Louisville to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from Louisville to Biloxi in the morning. Doing so could potentially save you 26% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Louisville to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Louisville to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Louisville to Biloxi flight should consider departing on Monday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Louisville to Biloxi?

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Louisville to Biloxi by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Biloxi?

    For a flight from Louisville to Biloxi, you will be flying from Louisville Intl. Louisville Intl (SDF) is just 5.3 mi from the center of the city. Louisville Intl is the only Louisville airport and it handles 0 outbound flights to Biloxi per day. 6 airlines have flights to Biloxi from Louisville Intl on a regular basis.

  • How popular is this Louisville to Biloxi flight route?

    This flight path from Louisville Intl to Biloxi was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to Biloxi?

    For as low as $274, Delta can have you in Biloxi from Louisville in 3h 49m. Airlines will cover a distance of 569 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Louisville to Biloxi that include hotel bookings?

    Yes. In addition to deals on Louisville to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Biloxi.

  • Can I find deals for business class flights from Louisville to Biloxi?

    Yes. Cheapflights offers flight deals from Louisville to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Biloxi?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $82). Flying from Louisville to Biloxi in February is currently the most expensive (average of $144). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Louisville to Biloxi

Discover the top 6 airlines that operate flights from Louisville to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$109Average$176FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$138Average$230FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$183Average$366FlexibilityNo cancel feeOn-time69%
DeltaCheapest$198Average$379FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$217Average$336FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$248Average$402FlexibilityNo cancel feeOn-time63%

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