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Biloxi

$160+ Cheap flights from Louisville (SDF) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — MSY
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Louisville to Biloxi

Cheapest flights from Louisville to Biloxi
Explore the most affordable flight options available from Louisville to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:48 amSDF - GPT
1 stop7h 40mAmerican Airlines
Sat 12/204:38 pmGPT - SDF
1 stop6h 43mAmerican Airlines
Deal found 12/16$746
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:03 amSDF - GPT
2 stops7h 13mAmerican Airlines
Sat 12/207:36 pmGPT - SDF
1 stop13h 32mAmerican Airlines
Deal found 12/16$809
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:05 amSDF - GPT
2 stops7h 58mUnited Airlines
Sat 12/205:15 pmGPT - SDF
2 stops24h 56mUnited Airlines
Deal found 12/16$873

Find flight deals from Louisville to Biloxi

Keep the following information in mind while searching for Louisville to Biloxi flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$319
(American Airlines)

One-way from

$160
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$508
Provider with most accurate pricing for Louisville Intl-Gulfport Biloxi Regional flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Gulfport Biloxi Regional flights.
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From Louisville Intl to Biloxi
Search Deals
One-way flight from Louisville Intl to Biloxi
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Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Louisville to Biloxi that are best for you.

Fly from

Louisville

Fly to

Biloxi

Route

Depart

Return

Price

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Sun 3/1

6:20 pm-10:57 pm

1 stop5h 37m

Gulfport Biloxi Regional

Wed 3/11

4:28 pm-10:40 pm

1 stop5h 12m

$319

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Sat 1/24

3:30 pm-7:48 pm

1 stop5h 18m

Gulfport Biloxi Regional

Wed 1/28

1:57 pm-9:59 pm

1 stop7h 02m

$339

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Sun 3/15

10:06 am-9:00 am

1 stop23h 54m

Gulfport Biloxi Regional

Sun 3/22

7:20 pm-11:37 am

1 stop15h 17m

$343

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Sun 3/1

5:35 am-4:01 pm

2 stops11h 26m

Gulfport Biloxi Regional

Wed 3/11

2:00 pm-9:59 pm

1 stop6h 59m

$425

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Thu 12/25

9:05 am-4:03 pm

1 stop7h 58m

$160

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Wed 12/24

3:25 pm-9:37 pm

1 stop7h 12m

$205

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Thu 12/25

6:03 am-4:14 pm

2 stops11h 11m

$235

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Thu 12/25

5:05 am-7:10 pm

2 stops15h 05m

$253

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 12/29

6:51 pm-9:40 pm

1 stop3h 49m

$274

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Tue 12/30

6:51 pm-9:40 pm

1 stop3h 49m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 15 results
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Best time to book a flight from Louisville to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Biloxi

What is the cheapest month to book a flight from Louisville to Biloxi?

Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $79). Flying from Louisville to Biloxi in February is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to B1L?

Find hourly flight availability from Louisville to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s typically best to fly out from Louisville to Biloxi in the morning. Doing so could potentially save you 19% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Louisville to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Louisville to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Louisville to Biloxi flight should consider departing on Monday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated December 16, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Louisville to Biloxi by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Biloxi?

    For a flight from Louisville to Biloxi, you will be flying from Louisville Intl. Louisville Intl (SDF) is just 5.3 mi from the center of the city. Louisville Intl is the only Louisville airport and it handles 0 outbound flights to Biloxi per day. 6 airlines have flights to Biloxi from Louisville Intl on a regular basis.

  • How popular is this Louisville to Biloxi flight route?

    This flight path from Louisville Intl to Biloxi was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to Biloxi?

    For as low as $339, American Airlines can have you in Biloxi from Louisville in 5h 18m. Airlines will cover a distance of 569 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Louisville to Biloxi that include hotel bookings?

    Yes. In addition to deals on Louisville to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Biloxi.

  • Can I find deals for business class flights from Louisville to Biloxi?

    Yes. Cheapflights offers flight deals from Louisville to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Biloxi?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $79). Flying from Louisville to Biloxi in February is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Louisville to Biloxi

Discover the top 6 airlines that operate flights from Louisville to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$109Average$182FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$127Average$230FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$162Average$323FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$183Average$369FlexibilityNo cancel feeOn-time69%
DeltaCheapest$198Average$381FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$248Average$397FlexibilityNo cancel feeOn-time63%

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