HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$120+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — MSY
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Biloxi

Cheapest flights from Detroit to Biloxi
Explore the most affordable flight options available from Detroit to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:22 pmDTW - GPT
1 stop24h 48mMultiple Airlines
Sun 1/47:50 pmGPT - DTW
2 stops14h 03mMultiple Airlines
Deal found 12/15$351
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:13 pmDTW - GPT
1 stop4h 27mDelta
Thu 1/16:00 amGPT - DTW
1 stop5h 36mDelta
Deal found 12/16$389
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:11 pmDTW - GPT
1 stop8h 01mAmerican Airlines
Thu 1/14:48 pmGPT - DTW
1 stop4h 46mAmerican Airlines
Deal found 12/15$399
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:15 amDTW - GPT
2 stops9h 48mUnited Airlines
Thu 1/15:15 pmGPT - DTW
1 stop5h 28mUnited Airlines
Deal found 12/16$422
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amDTW - GPT
1 stop7h 16mAmerican Airlines
Fri 12/264:48 pmGPT - DTW
1 stop6h 56mAmerican Airlines
Deal found 12/15$429
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amDTW - GPT
2 stops11h 14mAmerican Airlines
Thu 1/17:05 amGPT - DTW
2 stops11h 25mAmerican Airlines
Deal found 12/16$495
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:58 pmDTW - GPT
1 stop16h 01mMultiple Airlines
Tue 12/3010:05 amGPT - DTW
2 stops31h 06mMultiple Airlines
Deal found 12/16$586
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:15 amDTW - GPT
1 stop7h 11mDelta
Thu 12/255:21 pmGPT - DTW
1 stop6h 36mDelta
Deal found 12/16$593

Find flight deals from Detroit to Biloxi

Keep the following information in mind while searching for Detroit to Biloxi flight deals. Data was last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$212
(Kiwi.com)

One-way from

$120
(Delta)

Popular in

February

Cheapest in

August

Average price

$403
Provider with most accurate pricing for Detroit (DTT)-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Gulfport Biloxi Regional flights.
Search Deals
From Detroit Metropolitan Wayne County to Biloxi
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Biloxi
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($140 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Biloxi that are best for you.

Fly from

Detroit

Fly to

Biloxi

Route

Depart

Return

Price

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Tue 1/27

5:15 am-9:33 am

1 stop5h 18m

Gulfport Biloxi Regional

Wed 1/28

10:21 am-3:14 pm

1 stop3h 53m

$239

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sun 1/18

12:59 pm-9:00 am

1 stop21h 01m

Gulfport Biloxi Regional

Fri 1/23

6:54 pm-10:57 pm

2 stops27h 03m

$245

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Thu 1/15

12:56 pm-9:00 am

1 stop21h 04m

Gulfport Biloxi Regional

Mon 1/19

6:54 pm-1:06 pm

1 stop17h 12m

$250

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sat 2/21

7:45 pm-11:59 pm

1 stop5h 14m

Gulfport Biloxi Regional

Wed 2/25

6:30 am-12:14 pm

1 stop4h 44m

$254

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sun 1/18

8:15 am-1:22 pm

1 stop6h 07m

Gulfport Biloxi Regional

Fri 1/23

5:13 pm-11:59 pm

1 stop5h 46m

$279

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Mon 1/26

8:15 am-1:22 pm

1 stop6h 07m

Gulfport Biloxi Regional

Wed 1/28

1:57 pm-10:04 pm

1 stop7h 07m

$279

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Mon 1/26

4:16 pm-9:53 pm

1 stop6h 37m

Gulfport Biloxi Regional

Tue 1/27

10:21 am-5:15 pm

1 stop5h 54m

$279

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Tue 1/27

6:15 am-9:33 am

1 stop4h 18m

Gulfport Biloxi Regional

Thu 1/29

6:08 pm-12:44 am

1 stop5h 36m

$279

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sun 1/25

8:15 am-1:51 pm

1 stop6h 36m

Gulfport Biloxi Regional

Wed 1/28

10:21 am-3:14 pm

1 stop3h 53m

$279

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sun 1/25

6:04 pm-9:53 pm

1 stop4h 49m

Gulfport Biloxi Regional

Tue 1/27

10:21 am-5:15 pm

1 stop5h 54m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 14 results
1
2

Best time to book a flight from Detroit to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Biloxi

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Biloxi?

Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Biloxi (average of $91). Flying from Detroit Metropolitan Wayne County Airport to Biloxi in June is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to B1L?

Find hourly flight availability from Detroit to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

One of the essential ways to save on airfare from Detroit Metropolitan Wayne County Airport to Biloxi is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Biloxi flight should consider departing on Sunday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Biloxi?

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated December 17, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Biloxi to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Biloxi?

    Most people fly from Detroit Metropolitan Wayne County (DTW) if they book a flight from Detroit to Biloxi. On average, Detroit Metropolitan Wayne County has 0 outbound flights to Biloxi per day from 6 airlines. Detroit Metropolitan Wayne County is conveniently located just 17.3 mi from Detroit’s city center.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Biloxi?

    For as low as $254, Delta can have you in Biloxi from Detroit Metropolitan Wayne County Airport in 5h 14m. Detroit Metropolitan Wayne County Airport and Biloxi are separated by a distance of 875 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Biloxi?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Biloxi on time: Spirit Airlines (93%), Air France (90%), WestJet (89%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Biloxi?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Biloxi is $70. On average you can expect to pay $244. The most popular route, (Detroit Metropolitan Wayne County - Gulfport Biloxi Regional), can usually be booked for $212.

  • Can I find deals for flights from Detroit to Biloxi that include hotel bookings?

    Yes. In addition to deals on Detroit to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Biloxi.

  • Can I find deals for business class flights from Detroit to Biloxi?

    Yes. Cheapflights offers flight deals from Detroit to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Biloxi?

    Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Biloxi (average of $91). Flying from Detroit Metropolitan Wayne County Airport to Biloxi in June is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 6 airlines flying from Detroit to Biloxi

Discover the top 6 airlines that operate flights from Detroit to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$98Average$214FlexibilityNo cancel feeOn-time65%
FrontierCheapest$140Average$245FlexibilityNo cancel feeOn-time62%
DeltaCheapest$199Average$393FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$211Average$368FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$216Average$385FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$288Average$388FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.