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Biloxi

$174+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — MSY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Detroit to Biloxi

Keep the following information in mind while searching for Detroit to Biloxi flight deals. Data was last updated September 16, 2025.

Round-trip from

$247
(Kiwi.com)

One-way from

$174
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$311
From Detroit Metropolitan Wayne County to Biloxi
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One-way flight from Detroit Metropolitan Wayne County to Biloxi
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Highest demand for flights based on searches. 24% potential increase in price ($120 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Detroit to Biloxi

Cheapest flights from Detroit to Biloxi
Explore the most affordable flight options available from Detroit to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:12 pmDTW - GPT
1 stop15h 47mMultiple Airlines
Sun 10/267:55 pmGPT - DTW
1 stop11h 43mMultiple Airlines
Deal found 9/14$247
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:45 amDTW - GPT
1 stop4h 31mDelta
Tue 10/212:31 pmGPT - DTW
1 stop6h 11mDelta
Deal found 9/16$249
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/141:42 pmDTW - GPT
2 stops10h 04mAmerican Airlines
Tue 10/216:15 amGPT - DTW
1 stop4h 52mAmerican Airlines
Deal found 9/16$254
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:12 pmDTW - GPT
1 stop15h 47mMultiple Airlines
Sun 10/197:55 pmGPT - DTW
2 stops35h 21mMultiple Airlines
Deal found 9/14$272
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 pmDTW - GPT
1 stop5h 07mDelta
Mon 12/225:15 pmGPT - DTW
1 stop6h 30mDelta
Deal found 9/15$274
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:05 pmDTW - GPT
1 stop8h 27mAmerican Airlines
Tue 9/305:30 amGPT - DTW
1 stop7h 50mAmerican Airlines
Deal found 9/15$284
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:40 pmDTW - GPT
1 stop5h 06mAmerican Airlines
Mon 10/276:18 pmGPT - DTW
1 stop5h 31mAmerican Airlines
Deal found 9/14$294
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:51 pmDTW - GPT
1 stop4h 51mAmerican Airlines
Sun 10/56:34 pmGPT - DTW
1 stop5h 09mAmerican Airlines
Deal found 9/15$299
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:21 amDTW - GPT
1 stop9h 50mMultiple Airlines
Sun 10/267:55 pmGPT - DTW
1 stop11h 43mMultiple Airlines
Deal found 9/14$317

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Biloxi that are best for you.

Fly from

Detroit

Fly to

Biloxi

Route

Depart

Return

Price

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Thu 10/23

6:12 pm-8:59 am

1 stop15h 47m

Gulfport Biloxi Regional

Sun 10/26

7:55 pm-8:38 am

1 stop11h 43m

$247

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Tue 10/14

5:45 am-9:16 am

1 stop4h 31m

Gulfport Biloxi Regional

Tue 10/21

2:31 pm-9:42 pm

1 stop6h 11m

$249

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sun 2/15

5:04 am-9:44 am

1 stop5h 40m

Gulfport Biloxi Regional

Sat 2/21

12:46 pm-11:44 pm

2 stops9h 58m

$254

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sun 10/12

6:12 pm-8:59 am

1 stop15h 47m

Gulfport Biloxi Regional

Sun 10/19

7:55 pm-8:16 am

2 stops35h 21m

$272

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Thu 12/18

6:00 pm-10:07 pm

1 stop5h 07m

Gulfport Biloxi Regional

Mon 12/22

5:15 pm-12:45 am

1 stop6h 30m

$274

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Wed 10/1

6:51 pm-10:42 pm

1 stop4h 51m

Gulfport Biloxi Regional

Sun 10/5

6:34 pm-12:43 am

1 stop5h 09m

$299

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Tue 10/14

1:42 pm-10:46 pm

2 stops10h 04m

Gulfport Biloxi Regional

Tue 10/21

6:15 am-5:34 pm

2 stops10h 19m

$304

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Fri 10/24

9:21 am-6:11 pm

1 stop9h 50m

Gulfport Biloxi Regional

Sun 10/26

7:55 pm-8:38 am

1 stop11h 43m

$317

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sat 10/11

10:25 pm-8:59 am

2 stops35h 34m

$174

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Fri 11/21

6:00 am-12:23 pm

1 stop7h 23m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 15 results
1
2

Best time to book a flight from Detroit to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Biloxi

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Biloxi?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Biloxi (average of $256). Flying from Detroit Metropolitan Wayne County Airport to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to B1L?

Find hourly flight availability from Detroit to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit Metropolitan Wayne County Airport to Biloxi as you normally would.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Biloxi. Price data was last updated on September 22, 2024.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Biloxi flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to Biloxi

Explore weekly flight availability from Detroit to Biloxi. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from DTW to B1L are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 16, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Biloxi to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Biloxi?

    Most people fly from Detroit Metropolitan Wayne County (DTW) if they book a flight from Detroit to Biloxi. On average, Detroit Metropolitan Wayne County has 0 outbound flights to Biloxi per day from 5 airlines. Detroit Metropolitan Wayne County is conveniently located just 17.3 mi from Detroit’s city center.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Biloxi?

    For as low as $249, Delta can have you in Biloxi from Detroit Metropolitan Wayne County Airport in 4h 31m. Detroit Metropolitan Wayne County Airport and Biloxi are separated by a distance of 875 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Biloxi?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Biloxi on time: WestJet (83%), Spirit Airlines (78%), KLM (77%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Biloxi?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Biloxi is $48. On average you can expect to pay $233. The most popular route, (Detroit Metropolitan Wayne County - Gulfport Biloxi Regional), can usually be booked for $247.

  • Can I find deals for flights from Detroit to Biloxi that include hotel bookings?

    Yes. In addition to deals on Detroit to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Biloxi.

  • Can I find deals for business class flights from Detroit to Biloxi?

    Yes. Cheapflights offers flight deals from Detroit to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Biloxi (average of $256). Flying from Detroit Metropolitan Wayne County Airport to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Detroit to Biloxi

Discover the top 5 airlines that operate flights from Detroit to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$99Average$226FlexibilityNo cancel feeOn-time65%
DeltaCheapest$199Average$409FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$417FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$221Average$395FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$482FlexibilityNo cancel feeOn-time69%

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