HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$106+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — MSY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Biloxi

Keep the following information in mind while searching for Detroit to Biloxi flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(American Airlines)

One-way from

$106
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$303
Provider with most accurate pricing for Detroit (DTT)-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Gulfport Biloxi Regional flights.
Search Deals
From Detroit Metropolitan Wayne County to Biloxi
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Biloxi
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($123 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Detroit to Biloxi

Cheapest flights from Detroit to Biloxi
Explore the most affordable flight options available from Detroit to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:22 pmDTW - GPT
1 stop7h 35mAmerican Airlines
Thu 11/207:15 amGPT - DTW
1 stop6h 37mAmerican Airlines
Deal found 10/28$299
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:45 amDTW - GPT
1 stop4h 31mDelta
Wed 11/126:03 pmGPT - DTW
1 stop5h 35mDelta
Deal found 10/28$309
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/114:47 pmDTW - GPT
1 stop5h 49mUnited Airlines
Sat 11/157:00 amGPT - DTW
2 stops8h 57mUnited Airlines
Deal found 10/29$314
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:17 pmDTW - GPT
2 stops24h 58mMultiple Airlines
Sun 11/167:55 pmGPT - DTW
1 stop21h 25mMultiple Airlines
Deal found 10/28$332
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:23 amDTW - GPT
1 stop6h 14mAmerican Airlines
Wed 11/126:43 amGPT - DTW
2 stops10h 36mAmerican Airlines
Deal found 10/29$344
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:48 amDTW - GPT
1 stop7h 06mAmerican Airlines
Mon 11/33:31 pmGPT - DTW
1 stop6h 24mAmerican Airlines
Deal found 10/28$369
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:15 amDTW - GPT
1 stop6h 05mUnited Airlines
Mon 11/311:52 amGPT - DTW
2 stops10h 43mUnited Airlines
Deal found 10/28$374

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Biloxi that are best for you.

Fly from

Detroit

Fly to

Biloxi

Route

Depart

Return

Price

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Thu 11/13

5:22 pm-11:57 pm

1 stop7h 35m

Gulfport Biloxi Regional

Thu 11/20

7:15 am-2:52 pm

1 stop6h 37m

$299

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Tue 11/11

4:47 pm-9:36 pm

1 stop5h 49m

Gulfport Biloxi Regional

Sat 11/15

7:00 am-3:59 pm

1 stop7h 59m

$309

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Wed 11/5

5:45 am-9:16 am

1 stop4h 31m

Gulfport Biloxi Regional

Wed 11/12

6:03 pm-12:38 am

1 stop5h 35m

$309

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Wed 11/12

7:17 pm-7:15 pm

2 stops24h 58m

Gulfport Biloxi Regional

Sun 11/16

7:55 pm-6:20 pm

1 stop21h 25m

$332

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Wed 11/5

7:23 am-12:37 pm

1 stop6h 14m

Gulfport Biloxi Regional

Wed 11/12

6:43 am-6:19 pm

2 stops10h 36m

$344

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Wed 11/5

6:00 am-4:02 pm

2 stops11h 02m

Gulfport Biloxi Regional

Wed 11/12

7:00 am-7:06 pm

2 stops11h 06m

$389

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sat 12/13

7:42 pm-7:15 pm

1 stop24h 33m

$106

DetroitGulfport

DTW - GPT

DTWGPT

Detroit Metropolitan Wayne County

Sat 12/20

10:10 am-4:08 pm

1 stop6h 58m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Best time to book a flight from Detroit to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Biloxi

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Biloxi?

Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Biloxi (average of $91). Flying from Detroit Metropolitan Wayne County Airport to Biloxi in June is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to B1L?

Find hourly flight availability from Detroit to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Detroit Metropolitan Wayne County Airport to Biloxi is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Biloxi flight should consider departing on Sunday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Biloxi to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Biloxi?

    Most people fly from Detroit Metropolitan Wayne County (DTW) if they book a flight from Detroit to Biloxi. On average, Detroit Metropolitan Wayne County has 0 outbound flights to Biloxi per day from 5 airlines. Detroit Metropolitan Wayne County is conveniently located just 17.3 mi from Detroit’s city center.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Biloxi?

    For as low as $309, American Airlines can have you in Biloxi from Detroit Metropolitan Wayne County Airport in 4h 31m. Detroit Metropolitan Wayne County Airport and Biloxi are separated by a distance of 875 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Biloxi?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Biloxi on time: Spirit Airlines (90%), Delta (79%), WestJet (79%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Biloxi?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Biloxi is $68. On average you can expect to pay $231. The most popular route, (Detroit Metropolitan Wayne County - Gulfport Biloxi Regional), can usually be booked for $249.

  • Can I find deals for flights from Detroit to Biloxi that include hotel bookings?

    Yes. In addition to deals on Detroit to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Biloxi.

  • Can I find deals for business class flights from Detroit to Biloxi?

    Yes. Cheapflights offers flight deals from Detroit to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Biloxi?

    Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Biloxi (average of $91). Flying from Detroit Metropolitan Wayne County Airport to Biloxi in June is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Detroit to Biloxi

Discover the top 5 airlines that operate flights from Detroit to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$98Average$220FlexibilityNo cancel feeOn-time65%
DeltaCheapest$199Average$420FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$418FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$221Average$395FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$318Average$443FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.