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Antigua

$760+ Cheap flights from Knoxville (TYS) to Antigua

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ANU
May 10 — May 171
Sun 5/10
Sun 5/17
1 adult, Economy
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Cheap flight deals from Knoxville to Antigua

Cheapest flights from Knoxville to Antigua
Explore the most affordable flight options available from Knoxville to Antigua. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:30 am
TYS
-
ANU
1 stop9h 49m
American Airlines
Fri 5/82:35 pm
ANU
-
TYS
1 stop9h 24m
American Airlines
Deal found 4/7$760
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:30 am
TYS
-
ANU
1 stop9h 49m
American Airlines
Sat 4/183:25 pm
ANU
-
TYS
1 stop17h 07m
American Airlines
Deal found 4/6$953
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
TYS
-
ANU
1 stop7h 33m
American Airlines
Sun 7/51:25 pm
ANU
-
TYS
2 stops21h 33m
American Airlines
Deal found 4/9$1,077

Find flight deals from Knoxville to Antigua

Keep the following information in mind while searching for Knoxville to Antigua flight deals. Data was last updated April 10, 2026.

Round-trip from

$760
(American Airlines)
From Knoxville McGhee Tyson to Antigua
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Antigua that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Knoxville to Antigua that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Sun 5/3

6:30 am-4:19 pm

1 stop9h 49m

St. John's V.C. Bird Intl

Fri 5/8

2:35 pm-11:59 pm

1 stop9h 24m

$760

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Tue 6/30

6:00 am-1:33 pm

1 stop7h 33m

St. John's V.C. Bird Intl

Sun 7/5

1:25 pm-10:58 am

2 stops21h 33m

$1,077

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/7

Sorted by cheapest first

Best time to book a flight from Knoxville to Antigua

Have a flexible travel schedule? Discover the best time to fly to Antigua from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Antigua
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Antigua

Get insights into the airlines that provide service to Antigua. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Antigua. Reviews last updated April 10, 2026.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Antigua to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,564 reviews

Overall

7.1

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,564 reviews
American Airlines
7.1
Good
11,564 reviews

Overall

7.1

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Antigua. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Antigua?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Antigua.

  • How long is the flight from Knoxville to Antigua?

    American Airlines can get you from Knoxville to Antigua in just under 9h 49m. Your travel time can differ by up to . The distance between Knoxville and Antigua is about 1874 mi.

  • Can I find deals for flights from Knoxville to Antigua that include hotel bookings?

    Yes. In addition to deals on Knoxville to Antigua flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Antigua?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Antigua.

  • Can I find deals for business class flights from Knoxville to Antigua?

    Yes. Cheapflights offers flight deals from Knoxville to Antigua by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Complete your trip

Complete your trip to Antigua by adding a car rental and/or hotel reservation to your travel itinerary.
St. John's V.C. Bird Intl Airport car rentals

Top airline flying from Knoxville to Antigua

Discover the top airline that operate flights from Knoxville to Antigua. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$593Average$814FlexibilityNo cancel feeOn-time71%

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