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Antigua

$397+ Cheap flights from Knoxville (TYS) to Antigua

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ANU
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Knoxville to Antigua

Keep the following information in mind while searching for Knoxville to Antigua flight deals. Data was last updated September 15, 2025.

Round-trip from

$678
(American Airlines)

One-way from

$397
(Kiwi.com)
From Knoxville McGhee Tyson to Antigua
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One-way flight from Knoxville McGhee Tyson to Antigua
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Find flight deals from Knoxville to Antigua

Cheapest flights from Knoxville to Antigua
Explore the most affordable flight options available from Knoxville to Antigua. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:11 pmTYS - ANU
2 stops19h 40mAmerican Airlines
Tue 10/142:55 pmANU - TYS
2 stops18h 57mAmerican Airlines
Deal found 9/13$678
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:58 amTYS - ANU
2 stops23h 27mMultiple Airlines
Thu 11/64:15 pmANU - TYS
2 stops31h 11mMultiple Airlines
Deal found 9/15$685
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:20 pmTYS - ANU
2 stops20h 26mAmerican Airlines
Thu 11/132:15 pmANU - TYS
2 stops20h 35mAmerican Airlines
Deal found 9/13$809
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:15 amTYS - ANU
1 stop9h 22mAmerican Airlines
Thu 11/62:15 pmANU - TYS
2 stops21h 37mAmerican Airlines
Deal found 9/15$1,016
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:53 pmTYS - ANU
1 stop20h 45mAmerican Airlines
Sat 1/34:04 pmANU - TYS
1 stop9h 34mAmerican Airlines
Deal found 9/15$2,527

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Antigua that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Knoxville to Antigua that are best for you.

Fly from

Knoxville

Fly to

Antigua

Route

Depart

Return

Price

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Thu 10/9

6:11 pm-1:51 pm

2 stops19h 40m

St. John's V.C. Bird Intl

Tue 10/14

2:55 pm-9:52 am

2 stops18h 57m

$678

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Thu 10/30

9:58 am-9:25 am

2 stops23h 27m

St. John's V.C. Bird Intl

Thu 11/6

4:15 pm-10:26 pm

2 stops31h 11m

$685

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Mon 11/10

7:20 pm-4:46 pm

2 stops20h 26m

St. John's V.C. Bird Intl

Thu 11/13

2:15 pm-9:50 am

2 stops20h 35m

$809

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Sat 12/27

6:53 pm-4:38 pm

1 stop20h 45m

St. John's V.C. Bird Intl

Sat 1/3

4:04 pm-12:38 am

1 stop9h 34m

$2,527

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Sat 9/27

4:31 pm-2:10 pm

2 stops21h 39m

$397

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Tue 9/30

8:00 am-11:00 am

3 stops51h 00m

$443

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Fri 9/26

1:22 pm-9:10 am

3 stops43h 48m

$444

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Thu 9/25

12:08 pm-9:45 am

3 stops45h 37m

$513

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Sun 9/28

5:20 pm-3:09 pm

2 stops21h 49m

$538

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Sun 9/28

12:08 pm-5:15 pm

3 stops29h 07m

$538

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 13 results
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Best time to book a flight from Knoxville to Antigua

Have a flexible travel schedule? Discover the best time to fly to Antigua from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Antigua
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Antigua

Get insights into the airlines that provide service to Antigua. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Antigua. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Antigua to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Antigua. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Antigua?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Antigua.

  • How long is the flight from Knoxville to Antigua?

    American Airlines can get you from Knoxville to Antigua in just under 19h 40m. Your travel time can differ by up to . The distance between Knoxville and Antigua is about 1874 mi.

  • Can I find deals for flights from Knoxville to Antigua that include hotel bookings?

    Yes. In addition to deals on Knoxville to Antigua flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Antigua?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Antigua.

  • Can I find deals for business class flights from Knoxville to Antigua?

    Yes. Cheapflights offers flight deals from Knoxville to Antigua by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Antigua?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Antigua (average of $500). Flying from Knoxville to Antigua in June is currently the most expensive (average of $651). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Antigua

See prices for flight routes from nearby airports that may be better suited for you.
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Memphis to St. John's flights
Knoxville to St. John's flights

Top airline flying from Knoxville to Antigua

Discover the top airline that operate flights from Knoxville to Antigua. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$593Average$865FlexibilityNo cancel feeOn-time71%

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