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Antigua

$720+ Cheap flights from Knoxville (TYS) to Antigua

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ANU
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Knoxville to Antigua

Best flights from Knoxville to Antigua
Discover carefully curated flight deals from Knoxville to Antigua that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 21, 2025.

This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 amTYS - ANU
1 stop7h 43mAmerican Airlines
Sat 4/113:50 pmANU - TYS
1 stop7h 24mAmerican Airlines
Deal found 12/19$720

Find flight deals from Knoxville to Antigua

Keep the following information in mind while searching for Knoxville to Antigua flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$720
(American Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-St. John's V.C. Bird Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-St. John's V.C. Bird Intl flights.
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From Knoxville McGhee Tyson to Antigua
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Antigua that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Knoxville to Antigua that are best for you.

Fly from

Knoxville

Fly to

Antigua

Route

Depart

Return

Price

KnoxvilleSt. John's

TYS - ANU

TYSANU

Knoxville McGhee Tyson

Sun 4/5

6:00 am-1:43 pm

1 stop7h 43m

St. John's V.C. Bird Intl

Sat 4/11

3:50 pm-11:14 pm

1 stop7h 24m

$720

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Best time to book a flight from Knoxville to Antigua

Have a flexible travel schedule? Discover the best time to fly to Antigua from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Antigua
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Antigua

Get insights into the airlines that provide service to Antigua. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Antigua. Reviews last updated December 21, 2025.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Antigua to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.5

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.5

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Antigua. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Antigua?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Antigua.

  • How long is the flight from Knoxville to Antigua?

    American Airlines can get you from Knoxville to Antigua in just under 7h 43m. Your travel time can differ by up to . The distance between Knoxville and Antigua is about 1874 mi.

  • Can I find deals for flights from Knoxville to Antigua that include hotel bookings?

    Yes. In addition to deals on Knoxville to Antigua flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Antigua?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Antigua.

  • Can I find deals for business class flights from Knoxville to Antigua?

    Yes. Cheapflights offers flight deals from Knoxville to Antigua by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Alternative routes for Knoxville to Antigua

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Knoxville to Antigua

Discover the top airline that operate flights from Knoxville to Antigua. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$593Average$814FlexibilityNo cancel feeOn-time71%

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