HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$203+ Cheap flights from Louisville (SDF) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — MSY
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Louisville to Biloxi

Cheapest flights from Louisville to Biloxi
Explore the most affordable flight options available from Louisville to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:00 pm
SDF
-
GPT
1 stop4h 57m
American Airlines
Tue 2/2410:43 am
GPT
-
SDF
1 stop5h 54m
American Airlines
Deal found 1/20$269
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/97:40 am
SDF
-
GPT
1 stop5h 49m
American Airlines
Sat 2/144:29 pm
GPT
-
SDF
1 stop5h 14m
American Airlines
Deal found 1/20$274
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:40 am
SDF
-
GPT
1 stop5h 51m
American Airlines
Sat 2/71:03 pm
GPT
-
SDF
1 stop6h 44m
American Airlines
Deal found 1/20$279
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/11:15 pm
SDF
-
GPT
1 stop4h 40m
American Airlines
Sun 2/224:29 pm
GPT
-
SDF
1 stop6h 58m
American Airlines
Deal found 1/19$376
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
SDF
-
GPT
1 stop5h 13m
American Airlines
Fri 2/2710:43 am
GPT
-
SDF
1 stop7h 59m
American Airlines
Deal found 1/20$396
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:57 pm
SDF
-
GPT
1 stop5h 00m
American Airlines
Sat 3/141:04 pm
GPT
-
SDF
1 stop4h 59m
American Airlines
Deal found 1/21$405

Find flight deals from Louisville to Biloxi

Keep the following information in mind while searching for Louisville to Biloxi flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$203
(Delta)

Popular in

December

Cheapest in

July
Provider with most accurate pricing for Louisville Intl-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Gulfport Biloxi Regional flights.
Search Deals
From Louisville Intl to Biloxi
Search Deals
One-way flight from Louisville Intl to Biloxi
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Louisville to Biloxi that are best for you.

Fly from

Louisville

Fly to

Biloxi

Route

Depart

Return

Price

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Sat 2/21

8:00 pm-11:57 pm

1 stop4h 57m

Gulfport Biloxi Regional

Tue 2/24

10:43 am-5:37 pm

1 stop5h 54m

$269

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 2/9

7:40 am-12:29 pm

1 stop5h 49m

Gulfport Biloxi Regional

Sat 2/14

4:29 pm-10:43 pm

1 stop5h 14m

$274

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Tue 2/3

11:16 am-10:41 pm

2 stops12h 25m

Gulfport Biloxi Regional

Sat 2/7

6:32 am-12:25 pm

1 stop4h 53m

$284

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Sun 2/1

1:15 pm-4:55 pm

1 stop4h 40m

Gulfport Biloxi Regional

Sun 2/22

4:29 pm-12:27 am

1 stop6h 58m

$376

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 2/9

6:32 pm-11:33 pm

1 stop6h 01m

Gulfport Biloxi Regional

Fri 2/13

1:02 pm-7:12 pm

1 stop5h 10m

$406

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 3/23

6:00 am-8:50 am

1 stop3h 50m

Gulfport Biloxi Regional

Fri 3/27

5:57 pm-11:57 pm

1 stop5h 00m

$411

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Wed 4/15

8:15 am-1:57 pm

1 stop6h 42m

$203

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Wed 4/15

7:20 am-4:13 pm

2 stops9h 53m

$208

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Wed 4/15

12:33 pm-9:00 am

3 stops45h 27m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Best time to book a flight from Louisville to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Biloxi

What is the cheapest month to book a flight from Louisville to Biloxi?

Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $80). Flying from Louisville to Biloxi in March is currently the most expensive (average of $112). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to B1L?

Find hourly flight availability from Louisville to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2026.

It’s typically best to fly out from Louisville to Biloxi in the evening. Doing so could potentially save you 59% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated January 21, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Louisville to Biloxi by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,088 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,088 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Biloxi?

    For a flight from Louisville to Biloxi, you will be flying from Louisville Intl. Louisville Intl (SDF) is just 5.3 mi from the center of the city. Louisville Intl is the only Louisville airport and it handles 0 outbound flights to Biloxi per day. 6 airlines have flights to Biloxi from Louisville Intl on a regular basis.

  • How popular is this Louisville to Biloxi flight route?

    This flight path from Louisville Intl to Biloxi was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to Biloxi?

    For as low as $269, American Airlines can have you in Biloxi from Louisville in 4h 57m. Airlines will cover a distance of 569 mi.

  • Can I find deals for flights from Louisville to Biloxi that include hotel bookings?

    Yes. In addition to deals on Louisville to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Biloxi.

  • Can I find deals for business class flights from Louisville to Biloxi?

    Yes. Cheapflights offers flight deals from Louisville to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Biloxi?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $80). Flying from Louisville to Biloxi in March is currently the most expensive (average of $112). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to Biloxi

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Mobile flights
Cincinnati to Gulfport flights
Knoxville to Memphis flights
Nashville to Memphis flights
Louisville to Baton Rouge flights
Cincinnati to Jackson flights
Nashville to Gulfport flights
Nashville to Mobile flights
Cincinnati to Memphis flights
Lexington to Mobile flights
Nashville to Baton Rouge flights
Knoxville to Jackson flights
Cincinnati to Baton Rouge flights
Knoxville to Mobile flights
Knoxville to Gulfport flights
Nashville to Jackson flights
Louisville to Gulfport flights
Louisville to Mobile flights
Lexington to Gulfport flights
Lexington to Baton Rouge flights
Lexington to Memphis flights
Louisville to Memphis flights
Knoxville to Baton Rouge flights
Nashville to Alexandria flights
Lexington to Jackson flights
Lexington to Columbus flights
Cincinnati to Alexandria flights
Louisville to Alexandria flights
Owensboro to Baton Rouge flights
Blountville to Mobile flights
Huntington to Baton Rouge flights
Huntington to Gulfport flights
Blountville to Memphis flights
Knoxville to Alexandria flights
Evansville to Baton Rouge flights
Huntington to Mobile flights
Huntington to Jackson flights

Top 6 airlines flying from Louisville to Biloxi

Discover the top 6 airlines that operate flights from Louisville to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$74Average$173FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$125Average$230FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$162Average$349FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$183Average$366FlexibilityNo cancel feeOn-time69%
DeltaCheapest$198Average$384FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$248Average$390FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.