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Biloxi

$154+ Cheap flights from Louisville (SDF) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — MSY
May 12 — May 191
Tue 5/12
Tue 5/19
1 adult, Economy
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Cheap flight deals from Louisville to Biloxi

Cheapest flights from Louisville to Biloxi
Explore the most affordable flight options available from Louisville to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.

This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:08 pm
SDF
-
GPT
1 stop4h 53m
American Airlines
Tue 6/96:38 pm
GPT
-
SDF
1 stop4h 50m
American Airlines
Deal found 4/10$276
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:00 am
SDF
-
GPT
1 stop4h 05m
Delta
Mon 8/31:50 pm
GPT
-
SDF
1 stop6h 28m
Delta
Deal found 4/9$291
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:41 pm
SDF
-
GPT
1 stop6h 10m
American Airlines
Sat 5/95:03 pm
GPT
-
SDF
1 stop5h 08m
American Airlines
Deal found 4/9$304
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:41 pm
SDF
-
GPT
1 stop6h 10m
American Airlines
Tue 5/125:49 pm
GPT
-
SDF
1 stop4h 41m
American Airlines
Deal found 4/9$305
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
SDF
-
GPT
1 stop4h 21m
Delta
Thu 6/186:01 pm
GPT
-
SDF
1 stop5h 31m
Delta
Deal found 4/9$325
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:52 pm
SDF
-
GPT
1 stop5h 06m
American Airlines
Tue 4/215:00 am
GPT
-
SDF
1 stop6h 48m
American Airlines
Deal found 4/9$347
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:52 pm
SDF
-
GPT
1 stop5h 06m
American Airlines
Wed 5/66:09 pm
GPT
-
SDF
1 stop5h 16m
American Airlines
Deal found 4/8$348

Find flight deals from Louisville to Biloxi

Keep the following information in mind while searching for Louisville to Biloxi flight deals. Data was last updated April 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$276
(American Airlines)

One-way from

$154
(Kiwi.com)

Popular in

April

Cheapest in

July

Average price

$534
Provider with most accurate pricing for Louisville Intl-Gulfport Biloxi Regional flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Gulfport Biloxi Regional flights.
Search Deals
From Louisville Intl to Biloxi
Search Deals
One-way flight from Louisville Intl to Biloxi
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Louisville to Biloxi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 5/11

7:52 pm-11:58 pm

1 stop5h 06m

Gulfport Biloxi Regional

Mon 5/18

6:09 pm-12:25 am

1 stop5h 16m

$397
Quickest round-trip

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 5/22

6:00 am-9:21 am

1 stop4h 21m

Gulfport Biloxi Regional

Sun 5/24

6:32 am-11:53 am

1 stop4h 21m

$425

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 6/8

8:08 pm-12:01 am

1 stop4h 53m

Gulfport Biloxi Regional

Fri 6/12

6:38 pm-12:28 am

1 stop4h 50m

$439

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Mon 7/20

6:00 am-9:19 am

1 stop4h 19m

Gulfport Biloxi Regional

Thu 7/23

1:50 pm-9:18 pm

1 stop6h 28m

$439

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Tue 5/12

3:30 pm-7:53 pm

1 stop5h 23m

Gulfport Biloxi Regional

Sat 5/16

2:00 pm-8:00 pm

1 stop5h 00m

$483
Cheapest one-way

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Thu 8/13

11:12 am-7:41 am

1 stop21h 29m

$154

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 5/1

7:48 pm-6:40 pm

3 stops47h 52m

$209
Quickest one-way

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 5/1

6:00 am-9:24 am

1 stop4h 24m

$254

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Thu 8/13

6:08 am-12:13 pm

2 stops7h 05m

$259

LouisvilleGulfport

SDF - GPT

SDFGPT

Louisville Intl

Fri 5/1

3:30 pm-11:58 pm

2 stops9h 28m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/7

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Louisville to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Biloxi

What is the cheapest month to book a flight from Louisville to Biloxi?

Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $74). Flying from Louisville to Biloxi in June is currently the most expensive (average of $114). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to B1L?

Find hourly flight availability from Louisville to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 12, 2026.

It’s typically best to fly out from Louisville to Biloxi in the afternoon. Doing so could potentially save you 62% on the flight price compared to flying at noon, which is usually more expensive.

How much does it cost to fly round-trip from Louisville to Biloxi?

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated April 12, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Louisville to Biloxi by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,411 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,411 reviews
Delta
7.9
Good
8,411 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,572 reviews
Delta
7.9
Good
8,411 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Biloxi?

    For a flight from Louisville to Biloxi, you will be flying from Louisville Intl. Louisville Intl (SDF) is just 5.3 mi from the center of the city. Louisville Intl is the only Louisville airport and it handles 0 outbound flights to Biloxi per day. 7 airlines have flights to Biloxi from Louisville Intl on a regular basis.

  • How popular is this Louisville to Biloxi flight route?

    This flight path from Louisville Intl to Biloxi was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to Biloxi?

    For as low as $425, American Airlines can have you in Biloxi from Louisville in 4h 21m. Airlines will cover a distance of 569 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Louisville to Biloxi that include hotel bookings?

    Yes. In addition to deals on Louisville to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Biloxi.

  • Can I find deals for business class flights from Louisville to Biloxi?

    Yes. Cheapflights offers flight deals from Louisville to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Biloxi?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Biloxi (average of $74). Flying from Louisville to Biloxi in June is currently the most expensive (average of $114). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 7 airlines flying from Louisville to Biloxi

Discover the top 7 airlines that operate flights from Louisville to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$74Average$178FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$95Average$220FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$106Average$175FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$162Average$326FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$183Average$366FlexibilityNo cancel feeOn-time69%
DeltaCheapest$226Average$382FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$248Average$387FlexibilityNo cancel feeOn-time63%

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