Currently, May is the cheapest month in which you can book a flight from Des Moines to South America (average of $359). Flying from Des Moines to South America in July is currently the most expensive (average of $498). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How recently were the Des Moines to South America flight deals updated?

The Des Moines to South America flight deals you see on this page were last updated on 5/3.

What are the most popular routes from Des Moines to South America?

The most popular flight routes from Des Moines to South America are Des Moines - Sao Paulo Guarulhos Intl, Des Moines - Quito Mariscal Sucr and Des Moines - Belo Horizonte Tancredo Neves Intl.

Can I find flights from Des Moines to South America for under $500 on Cheapflights?

Yes, there are multiple flights from Des Moines to South America for under $500. The cheapest flight booked recently is on Delta for just $412, but on average you can expect to pay $667.

Are there last-minute flights available from Des Moines to South America for under $600?

There are currently 2+ open flights from Des Moines to South America within the next 7 days for less than $600.

What airport do you fly from for flights from Des Moines to South America?

Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South America.

What does DSM to BOG mean?

These are just IATA (International Air Transport Association) codes. They are used in aviation to identify and differentiate airports. That’s why a Des Moines Airport to Bogotá El Dorado Airport flight would often be abbreviated as a DSM to BOG flight. Sao Paulo Guarulhos Intl Airport (GRU), Lima J Chavez Intl Airport (LIM), Santiago Arturo Merino Benitez Airport (SCL), Medellín Jose Maria Cordova Intl Airport (MDE), Brasilia Airport (BSB) are other airports near this flight route and their unique identifiers/IATA codes.

Can I find deals for flights from Des Moines to South America that include extra baggage allowance?

The amount of baggage you can bring on your Des Moines to South America flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

Can I find deals on flights from Des Moines to South America with specific airlines?

Yes, Cheapflights allows you to browse and filter Des Moines to South America flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

Can I find deals for flights from Des Moines to South America that include hotel bookings?

Yes. In addition to deals on Des Moines to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South America.

Can I find deals for business class flights from Des Moines to South America?

Yes. Cheapflights offers flight deals from Des Moines to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Can I find deals for flights from Des Moines to South America that allow pets onboard?

Many airlines flying from Des Moines to South America offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

Can I find deals on last-minute flights from Des Moines to South America?

Yes, you can often find last-minute deals on Des Moines to South America flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

Flights from Des Moines, IA to South America from $412

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

When is the cheapest time to fly from Des Moines to South America (DSM - SA)?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to South America as you normally would.

Cheap Air Canada flights from Des Moines to South America

Wed 5/226:00 amDSM - EZE

3 stops30h 50mAir Canada

Wed 6/54:25 pmEZE - DSM

3 stops30h 26mAir Canada

Deal found 5/4$1,344

Wed 8/2111:30 amDSM - GRU

2 stops20h 40mAir Canada

Thu 8/228:50 pmGRU - DSM

2 stops19h 32mAir Canada

Deal found 5/3$1,365

Tue 9/178:00 amDSM - EZE

3 stops28h 50mAir Canada

Mon 9/304:25 pmEZE - DSM

3 stops25h 49mAir Canada

Deal found 5/4$1,430

Thu 10/108:00 amDSM - GRU

2 stops24h 10mAir Canada

Thu 10/249:00 pmGRU - DSM

2 stops19h 26mAir Canada

Deal found 5/4$1,646

Cheap United Airlines flights from Des Moines to South America

Thu 5/168:00 amDSM - UIO

2 stops15h 30mUnited Airlines

Wed 8/1412:40 amUIO - DSM

2 stops45h 09mUnited Airlines

Deal found 5/3$680

Mon 9/166:00 amDSM - LIM

2 stops17h 00mUnited Airlines

Tue 9/2412:55 amLIM - DSM

2 stops18h 35mUnited Airlines

Deal found 5/3$736

Thu 5/162:56 pmDSM - UIO

1 stop8h 34mUnited Airlines

Wed 8/1412:40 amUIO - DSM

1 stop21h 55mUnited Airlines

Deal found 5/3$745

Tue 9/176:00 amDSM - EZE

2 stops24h 00mUnited Airlines

Thu 10/39:00 pmEZE - DSM

2 stops19h 26mUnited Airlines

Deal found 5/4$1,024

Thu 10/36:00 amDSM - LIM

1 stop17h 00mUnited Airlines

Wed 10/2312:55 amLIM - DSM

1 stop21h 35mUnited Airlines

Deal found 5/3$1,026

Tue 9/1711:30 amDSM - EZE

2 stops18h 30mUnited Airlines

Sun 9/299:00 pmEZE - DSM

2 stops39h 28mUnited Airlines

Deal found 5/4$1,081

Thu 8/226:05 amDSM - CNF

2 stops32h 25mUnited Airlines

Mon 8/261:15 pmCNF - DSM

2 stops23h 18mUnited Airlines

Deal found 5/2$1,130

Mon 5/202:56 pmDSM - EZE

1 stop15h 04mUnited Airlines

Thu 6/69:00 pmEZE - DSM

1 stop19h 13mUnited Airlines

Deal found 5/4$1,444

Wed 8/216:45 pmDSM - GRU

1 stop12h 45mUnited Airlines

Thu 8/229:00 pmGRU - DSM

2 stops25h 05mUnited Airlines

Deal found 5/3$1,522

Cheap Des Moines to South America flights in May & June 2024

Thu 5/911:55 amDSM - UIO

1 stop9h 20mDelta

Fri 5/1011:15 pmUIO - DSM

1 stop18h 09mDelta

Deal found 5/3$595

Thu 5/96:30 amDSM - UIO

2 stops14h 45mDelta

Fri 5/1011:15 pmUIO - DSM

2 stops17h 45mDelta

Deal found 5/3$600

Thu 5/165:48 pmDSM - UIO

2 stops19h 11mAmerican Airlines

Thu 8/156:30 amUIO - DSM

2 stops16h 26mAmerican Airlines

Deal found 5/3$651

Thu 5/168:00 amDSM - UIO

2 stops15h 30mUnited Airlines

Wed 8/1412:40 amUIO - DSM

2 stops45h 09mUnited Airlines

Deal found 5/3$680

Thu 5/162:56 pmDSM - UIO

1 stop8h 34mUnited Airlines

Wed 8/1412:40 amUIO - DSM

1 stop21h 55mUnited Airlines

Deal found 5/3$745

Thu 5/1611:55 amDSM - UIO

1 stop9h 20mDelta

Thu 8/159:11 amUIO - DSM

2 stops13h 08mDelta

Deal found 5/3$880

Fri 5/1711:37 amDSM - EZE

3 stops35h 18mMultiple Airlines

Wed 5/292:32 pmEZE - DSM

2 stops32h 01mMultiple Airlines

Deal found 5/3$920

Thu 5/1611:55 amDSM - UIO

1 stop9h 20mDelta

Thu 8/1511:20 pmUIO - DSM

1 stop22h 59mDelta

Deal found 5/3$1,017

Sat 6/226:54 amDSM - SCL

2 stops22h 51mAmerican Airlines

Sat 7/69:25 pmSCL - DSM

2 stops27h 12mAmerican Airlines

Deal found 5/3$1,187

Des Moines to South America 2024 flight deals

Sat 9/286:00 amDSM - BAQ

2 stops24h 31mDelta

Wed 10/24:44 amBAQ - DSM

2 stops17h 40mDelta

Deal found 5/3$412

Sat 9/286:00 amDSM - BAQ

2 stops14h 01mDelta

Wed 10/24:44 amBAQ - DSM

2 stops13h 07mDelta

Deal found 5/2$427

Mon 11/412:39 pmDSM - UIO

2 stops24h 37mAmerican Airlines

Fri 11/153:05 pmUIO - DSM

2 stops22h 43mAmerican Airlines

Deal found 5/3$449

Tue 11/512:39 pmDSM - UIO

2 stops24h 37mAmerican Airlines

Sat 11/163:05 pmUIO - DSM

1 stop9h 42mAmerican Airlines

Deal found 5/3$450

Tue 11/56:45 pmDSM - UIO

2 stops28h 45mUnited Airlines

Fri 11/151:35 amUIO - DSM

2 stops13h 21mUnited Airlines

Deal found 5/3$469

Mon 11/45:30 pmDSM - UIO

2 stops24h 35mDelta

Fri 11/1511:59 pmUIO - DSM

1 stop11h 20mDelta

Deal found 5/3$481

Mon 11/46:45 pmDSM - UIO

2 stops52h 45mUnited Airlines

Thu 11/141:35 amUIO - DSM

2 stops33h 45mUnited Airlines

Deal found 5/3$532

Mon 11/46:45 pmDSM - UIO

2 stops52h 45mUnited Airlines

Thu 11/141:35 amUIO - DSM

1 stop21h 55mUnited Airlines

Deal found 5/3$533

Tue 11/56:58 amDSM - UIO

1 stop30h 18mAmerican Airlines

Sat 11/163:05 pmUIO - DSM

1 stop9h 42mAmerican Airlines

Deal found 5/3$574

Des Moines to South America flights leaving soon

Thu 5/911:55 amDSM - UIO

1 stop9h 20mDelta

Fri 5/1011:15 pmUIO - DSM

1 stop18h 09mDelta

Deal found 5/3$595

Thu 5/96:30 amDSM - UIO

2 stops14h 45mDelta

Fri 5/1011:15 pmUIO - DSM

2 stops17h 45mDelta

Deal found 5/3$600

One-way flights to South America from Des Moines

Sat 6/11:07 pmDSM - LIM

2 stops15h 03mAmerican Airlines

Deal found 5/2$536

Sat 6/17:02 amDSM - LIM

1 stop15h 23mAmerican Airlines

Deal found 5/2$537

Wed 9/182:14 pmDSM - CNF

2 stops21h 51mDelta

Deal found 5/3$553

Sat 6/14:30 pmDSM - LIM

3 stops26h 45mMultiple Airlines

Deal found 5/2$573

Wed 9/187:10 amDSM - CNF

3 stops23h 55mAmerican Airlines

Deal found 5/3$652

Sat 5/116:40 amDSM - CNF

3 stops25h 35mAmerican Airlines

Deal found 5/3$866

Sat 5/1111:40 amDSM - CNF

2 stops25h 00mAmerican Airlines

Deal found 5/3$867

Find flights from Des Moines to South America within your budget

Fly from

Fly to

Budget

$412 - $1,344

Route

Depart

Return

Price

Des MoinesBarranquilla E Cortissoz

DSM - BAQ

DSMBAQ

Des Moines

Sat 9/28

2 stops24h 31m

Barranquilla E Cortissoz

Wed 10/2

2 stops17h 40m

$412

Des MoinesBarranquilla E Cortissoz

DSM - BAQ

DSMBAQ

Des Moines

Sat 9/28

2 stops14h 01m

Barranquilla E Cortissoz

Wed 10/2

2 stops13h 07m

$427

Des MoinesBarranquilla E Cortissoz

DSM - BAQ

DSMBAQ

Des Moines

Sat 9/28

1 stop29h 19m

Barranquilla E Cortissoz

Wed 10/2

2 stops19h 03m

$626

Des MoinesLima J Chavez Intl

DSM - LIM

DSMLIM

Des Moines

Tue 9/17

1 stop10h 01m

Lima J Chavez Intl

Tue 9/24

2 stops17h 46m

$641

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Thu 5/16

2 stops19h 11m

Quito Mariscal Sucr

Thu 8/15

2 stops16h 26m

$651

Des MoinesLima J Chavez Intl

DSM - LIM

DSMLIM

Des Moines

Sat 9/14

2 stops12h 20m

Lima J Chavez Intl

Mon 9/23

2 stops20h 04m

$660

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Thu 5/16

2 stops15h 30m

Quito Mariscal Sucr

Wed 8/14

2 stops45h 09m

$680

Des MoinesLima J Chavez Intl

DSM - LIM

DSMLIM

Des Moines

Mon 7/22

2 stops31h 57m

Lima J Chavez Intl

Sun 7/28

1 stop14h 50m

$903

Des MoinesBuenos Aires Ministro Pistarini

DSM - EZE

DSMEZE

Des Moines

Wed 5/22

3 stops30h 50m

Buenos Aires Ministro Pistarini

Wed 6/5

3 stops30h 26m

$1,344

Flights are sorted by cheapest first

Deals found on 5/3

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Delta

8.1

Very good

10,838 reviews

Check prices

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Delta

8.1

Very good

10,838 reviews

Delta

8.1

Very good

10,838 reviews

Check prices

Reviews

1 / 10

Copa Airlines

8.0

Very good

2,806 reviews

Delta

8.1

Very good

10,838 reviews

Check prices

Reviews

1 / 10

United Airlines

7.4

Good

11,125 reviews

Delta

8.1

Very good

10,838 reviews

Check prices

Reviews

1 / 10

American Airlines

7.3

Good

14,728 reviews

Delta

8.1

Very good

10,838 reviews

Check prices

Reviews

1 / 10

Air Canada

7.0

Good

6,904 reviews

Delta

8.1

Very good

10,838 reviews

Check prices

Reviews

1 / 10

Related info for your journey

What airport do you fly from for flights from Des Moines to South America?
Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South America.
Can I find flights from Des Moines to South America for under $500 on Cheapflights?
Yes, there are multiple flights from Des Moines to South America for under $500. The cheapest flight booked recently is on Delta for just $412, but on average you can expect to pay $667.
Are there last-minute flights available from Des Moines to South America for under $600?
There are currently 2+ open flights from Des Moines to South America within the next 7 days for less than $600.
What are the most popular routes from Des Moines to South America?
The most popular flight routes from Des Moines to South America are Des Moines - Sao Paulo Guarulhos Intl, Des Moines - Quito Mariscal Sucr and Des Moines - Belo Horizonte Tancredo Neves Intl.
What does DSM to BOG mean?
These are just IATA (International Air Transport Association) codes. They are used in aviation to identify and differentiate airports. That’s why a Des Moines Airport to Bogotá El Dorado Airport flight would often be abbreviated as a DSM to BOG flight. Sao Paulo Guarulhos Intl Airport (GRU), Lima J Chavez Intl Airport (LIM), Santiago Arturo Merino Benitez Airport (SCL), Medellín Jose Maria Cordova Intl Airport (MDE), Brasilia Airport (BSB) are other airports near this flight route and their unique identifiers/IATA codes.
Can I find deals for flights from Des Moines to South America that include extra baggage allowance?
The amount of baggage you can bring on your Des Moines to South America flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.
Can I find deals on flights from Des Moines to South America with specific airlines?
Yes, Cheapflights allows you to browse and filter Des Moines to South America flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.
Can I find deals for flights from Des Moines to South America that include hotel bookings?
Yes. In addition to deals on Des Moines to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South America.
Can I find deals for business class flights from Des Moines to South America?
Yes. Cheapflights offers flight deals from Des Moines to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
Can I find deals for flights from Des Moines to South America that allow pets onboard?
Many airlines flying from Des Moines to South America offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.
Can I find deals on last-minute flights from Des Moines to South America?
Yes, you can often find last-minute deals on Des Moines to South America flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.
How recently were the Des Moines to South America flight deals updated?
The Des Moines to South America flight deals you see on this page were last updated on 5/3.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Des Moines to South America
See prices for flight routes from nearby airports that may be better suited for you.

Des Moines to Denver flights

Des Moines to Dallas/Fort Worth flights

Cedar Rapids to Denver flights

Des Moines to LaGuardia flights

Des Moines to Las Vegas flights

Des Moines to Sky Harbor Intl flights

Des Moines to O'Hare Intl flights

Cedar Rapids to Sky Harbor Intl flights

Cedar Rapids to Dallas/Fort Worth flights

Des Moines to John F Kennedy Intl flights

Des Moines to Seattle flights

Des Moines to Hobby flights

Cedar Rapids to Seattle flights

Des Moines to Reagan-National flights

Des Moines to Atlanta flights

Des Moines to Cancún flights

Des Moines to Boston flights

Cedar Rapids to Cancún flights

Cedar Rapids to Tampa flights

Cedar Rapids to Reagan-National flights

Des Moines to George Bush Intcntl flights

Cedar Rapids to John F Kennedy Intl flights

Cedar Rapids to Las Vegas flights

Cedar Rapids to Atlanta flights

Cedar Rapids to Orlando flights

Des Moines to Dulles Intl flights

Des Moines to Orlando flights

Cedar Rapids to Dulles Intl flights

Cedar Rapids to Los Angeles flights

Cedar Rapids to LaGuardia flights

Cedar Rapids to Boston flights

Des Moines to Nashville flights

Cedar Rapids to Newark flights

Des Moines to Miami flights

Des Moines to Midway flights

Des Moines to San Francisco flights

Des Moines to Baltimore flights

Cedar Rapids to Baltimore flights

Des Moines to Charles de Gaulle flights

Cedar Rapids to Haneda flights

Des Moines to Honolulu flights

Cedar Rapids to Charleston flights

Des Moines to Fort Lauderdale flights

Des Moines to Charlotte flights

Des Moines to Salt Lake City flights

Cedar Rapids to Ontario flights

Cedar Rapids to Salt Lake City flights

Des Moines to Austin flights

Des Moines to Panama City flights

Des Moines to San Diego flights

Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.

South America car rentals

Brazil car rentals

Colombia car rentals

Argentina car rentals

Venezuela car rentals

Bogotá El Dorado Airport car rentals

Sao Paulo Guarulhos Intl Airport car rentals

Lima J Chavez Intl Airport car rentals

Santiago Arturo Merino Benitez Airport car rentals

Medellín Jose Maria Cordova Intl Airport car rentals

Brasilia Airport car rentals

Fly to South America countries
Consider these flights traveling to countries located in South America.

Flights to Falkland Islands (Islas Malvinas)

Flights to French Guiana

Flights to Guyana

Flights to Peru

Flights to Paraguay

Flights to Saint Helena

Flights to Suriname

Flights to Uruguay

Flights to Venezuela

Des Moines to South America flights
Consider these flights traveling from Des Moines to South America.

Des Moines to Guarulhos Intl flights

Des Moines to Quito flights

Des Moines to Ministro Pistarini flights

Des Moines to Lima flights

Des Moines to Santiago flights

Des Moines to Guayaquil flights

Des Moines to Barranquilla flights

Des Moines to Fortaleza flights

Des Moines to Cartagena flights

Des Moines to La Paz flights

Des Moines to Punta Arenas flights

Top 3 airlines flying from Des Moines to South America

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$384	Average$835	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights
Delta	Cheapest$449	Average$929	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
American Airlines	Cheapest$459	Average$925	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights

San Francisco to Austin flights

Florida to New York flights

Kansas City to Los Angeles flights

Minneapolis to Seattle flights

Newark Airport to Paris flights

Sacramento to Hawaii flights

Portland to New York flights

Los Angeles to Charlotte flights

New York to Washington, D.C. flights

New York to Virginia flights

Denver to Orlando flights

Des Moines to South Pacific flights

Search flights from Des Moines to South America by cabin class

Book a flight to one of these trending destinations

Fly with Cheapflights

How does Cheapflights help users find flights from Des Moines to South America?

Cheapflights helps you search for flights from Des Moines to South America via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines to South America?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Des Moines to South America.

Can Cheapflights find flights from Des Moines to South America with no change fees?

Yes, we can. To see specific flights from Des Moines to South America with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Des Moines to South America become cheaper?

Of course! You can now track prices for flights from Des Moines to South America and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

View all available airlines

Cheap flights from Des Moines (DSM) to South America from $412

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.

When is the cheapest time to fly from Des Moines to South America (DSM - SA)?

Cheap Air Canada flights from Des Moines to South America

Cheap United Airlines flights from Des Moines to South America

Cheap Des Moines to South America flights in May & June 2024

Find cheap flight options from Des Moines to South America specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,864,334 searches. Prices were last updated on May 4, 2024.

Des Moines to South America 2024 flight deals

Discover exclusive flight deals for travel between Des Moines and South America in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,864,334 searches. Data last updated May 4, 2024.

Des Moines to South America flights leaving soon

One-way flights to South America from Des Moines

Find flights from Des Moines to South America within your budget

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Des Moines to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to South America?

Can I find flights from Des Moines to South America for under $500 on Cheapflights?

Are there last-minute flights available from Des Moines to South America for under $600?

What are the most popular routes from Des Moines to South America?

What does DSM to BOG mean?

Can I find deals for flights from Des Moines to South America that include extra baggage allowance?

Can I find deals on flights from Des Moines to South America with specific airlines?

Can I find deals for flights from Des Moines to South America that include hotel bookings?

How can I find direct flights from Des Moines to South America?

Can I find deals for business class flights from Des Moines to South America?

Can I find deals for flights from Des Moines to South America that allow pets onboard?

Can I find deals on last-minute flights from Des Moines to South America?

How recently were the Des Moines to South America flight deals updated?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to South AmericaSee prices for flight routes from nearby airports that may be better suited for you.

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Des Moines to South America

Popular flight searches

Check out other popular destinations found by fellow travelers in 2024

Search flights from Des Moines to South America by cabin class

Find flights from Des Moines to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Book a flight to one of these trending destinations

User searches for flights to these destinations increased 20% or more in the past 90 days compared to other destinations

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Des Moines to South America?

Why should you use Cheapflights to find cheap flight tickets from Des Moines to South America?

Can Cheapflights find flights from Des Moines to South America with no change fees?

Can Cheapflights notify me if prices for flights from Des Moines to South America become cheaper?

100% Free

Book with Flexibility

Travel Smart

Alternative routes for Des Moines to South America
See prices for flight routes from nearby airports that may be better suited for you.