$191+ Cheap flights from Portland, ME to Louisville (PWM - SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SDF
Jul 12 — Jul 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to LouisvilleExplore the most affordable flight options available from Portland to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Portland to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
PWM
- SDF
1 stop6h 56m
Delta
Tue 9/157:55 am
SDF
- PWM
1 stop4h 15m
Delta
Deal found 6/10![Delta logo]()
$283
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:15 am
PWM
- SDF
1 stop5h 03m
United Airlines
Tue 9/155:15 am
SDF
- PWM
2 stops9h 23m
United Airlines
Deal found 6/10![United Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:15 am
PWM
- SDF
1 stop5h 08m
United Airlines
Sat 8/151:50 pm
SDF
- PWM
1 stop7h 33m
United Airlines
Deal found 6/10![United Airlines logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:15 am
PWM
- SDF
1 stop5h 03m
United Airlines
Sat 9/191:55 pm
SDF
- PWM
1 stop4h 34m
United Airlines
Deal found 6/9![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
PWM
- SDF
1 stop4h 55m
Delta
Mon 9/1411:45 am
SDF
- PWM
1 stop5h 04m
Delta
Deal found 6/10![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:05 pm
PWM
- SDF
2 stops8h 50m
Southwest
Mon 9/142:15 pm
SDF
- PWM
1 stop7h 15m
Southwest
Deal found 6/10![Southwest logo]()
$323
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:28 am
PWM
- SDF
1 stop4h 39m
American Airlines
Sat 8/296:18 pm
SDF
- PWM
1 stop5h 19m
American Airlines
Deal found 6/10![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:15 am
PWM
- SDF
1 stop5h 03m
United Airlines
Sat 8/297:10 am
SDF
- PWM
2 stops7h 28m
United Airlines
Deal found 6/10![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:40 am
PWM
- SDF
1 stop7h 00m
Southwest
Sat 8/293:50 pm
SDF
- PWM
1 stop5h 10m
Southwest
Deal found 6/10![Southwest logo]()
$340
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:30 am
PWM
- SDF
2 stops10h 00m
Southwest
Sat 8/296:45 am
SDF
- PWM
2 stops8h 15m
Southwest
Deal found 6/10![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
PWM
- SDF
1 stop6h 22m
United Airlines
Wed 9/97:10 am
SDF
- PWM
1 stop7h 21m
United Airlines
Deal found 6/11![United Airlines logo]()
$353
Best flights from Portland to LouisvilleDiscover carefully curated flight deals from Portland to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Portland to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
PWM
- SDF
1 stop4h 55m
Delta
Mon 9/1411:45 am
SDF
- PWM
1 stop5h 04m
Delta
Deal found 6/10![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:05 pm
PWM
- SDF
2 stops8h 50m
Southwest
Mon 9/142:15 pm
SDF
- PWM
1 stop7h 15m
Southwest
Deal found 6/10![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
PWM
- SDF
1 stop6h 22m
United Airlines
Wed 9/97:10 am
SDF
- PWM
1 stop7h 21m
United Airlines
Deal found 6/11![United Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:55 am
PWM
- SDF
1 stop4h 05m
Southwest
Sat 9/196:45 am
SDF
- PWM
2 stops8h 15m
Southwest
Deal found 6/9![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:30 am
PWM
- SDF
1 stop6h 57m
Delta
Fri 8/215:59 pm
SDF
- PWM
1 stop5h 31m
Delta
Deal found 6/10![Delta logo]()
$371
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:30 am
PWM
- SDF
2 stops6h 35m
Southwest
Tue 7/144:15 pm
SDF
- PWM
1 stop5h 20m
Southwest
Deal found 6/9![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:55 am
PWM
- SDF
2 stops7h 10m
Southwest
Mon 9/142:15 pm
SDF
- PWM
1 stop7h 15m
Southwest
Deal found 6/9![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:35 am
PWM
- SDF
2 stops10h 20m
Southwest
Mon 7/63:35 pm
SDF
- PWM
2 stops8h 35m
Southwest
Deal found 6/7![Southwest logo]()
$416
Last-minute flights from Portland to LouisvilleDiscover last-minute flight deals from Portland to Louisville. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Louisville. Data last updated June 12, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:45 pm
PWM
- SDF
1 stop7h 25m
Southwest
Fri 7/105:05 pm
SDF
- PWM
1 stop7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:30 am
PWM
- SDF
2 stops6h 35m
Southwest
Tue 7/144:15 pm
SDF
- PWM
1 stop5h 20m
Southwest
Deal found 6/9![Southwest logo]()
$360
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:15 am
PWM
- SDF
1 stop5h 08m
United Airlines
Tue 7/1410:05 am
SDF
- PWM
1 stop4h 29m
United Airlines
Deal found 6/9![United Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:45 pm
PWM
- SDF
1 stop7h 30m
Southwest
Tue 7/284:15 pm
SDF
- PWM
1 stop6h 45m
Southwest
Deal found 6/8![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:45 pm
PWM
- SDF
1 stop7h 30m
Southwest
Sat 7/255:15 pm
SDF
- PWM
1 stop6h 30m
Southwest
Deal found 6/10![Southwest logo]()
$368
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:15 am
PWM
- SDF
1 stop5h 08m
United Airlines
Tue 8/41:48 pm
SDF
- PWM
1 stop5h 39m
United Airlines
Deal found 6/11![United Airlines logo]()
$374
One-way flights from Portland to LouisvilleSearch for one-way flight options from Portland to Louisville. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from Portland to Louisville. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:35 am
PWM
- SDF
1 stop6h 35m
Southwest
Deal found 6/10![Southwest logo]()
$191
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:12 pm
PWM
- SDF
1 stop7h 47m
Delta
Deal found 6/10![Delta logo]()
$204
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:20 pm
PWM
- SDF
2 stops7h 10m
Southwest
Deal found 6/10![Southwest logo]()
$209
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:35 am
PWM
- SDF
2 stops8h 50m
Southwest
Deal found 6/10![Southwest logo]()
$219
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
PWM
- SDF
1 stop6h 56m
Delta
Deal found 6/9![Delta logo]()
$240
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am
PWM
- SDF
2 stops9h 30m
Southwest
Deal found 6/8![Southwest logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:22 pm
PWM
- SDF
3 stops36h 14m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:00 am
PWM
- SDF
3 stops25h 36m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$285
Find flight deals from Portland to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $283 (Delta) |
One-way from | $191 (Southwest) |
Popular in | September |
Cheapest in | February |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Portland to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Thu 9/10
6:00 am-10:55 am
1 stop4h 55m
Louisville Intl
Mon 9/14
11:45 am-4:49 pm
1 stop5h 04m
$317
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Thu 9/10
1:05 pm-9:55 pm
2 stops8h 50m
Louisville Intl
Mon 9/14
2:15 pm-9:30 pm
1 stop7h 15m
$323
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Sat 9/5
6:00 am-12:22 pm
1 stop6h 22m
Louisville Intl
Wed 9/9
7:10 am-2:31 pm
1 stop7h 21m
$353
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Mon 9/14
5:55 am-10:00 am
1 stop4h 05m
Louisville Intl
Sat 9/19
6:45 am-3:00 pm
2 stops8h 15m
$358
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Tue 7/7
5:30 am-12:05 pm
2 stops6h 35m
Louisville Intl
Tue 7/14
4:15 pm-9:35 pm
1 stop5h 20m
$360
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Mon 9/14
5:55 am-1:05 pm
2 stops7h 10m
Louisville Intl
Mon 9/14
2:15 pm-9:30 pm
1 stop7h 15m
$368
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Fri 8/21
6:30 am-1:27 pm
1 stop6h 57m
Louisville Intl
Fri 8/21
5:59 pm-11:30 pm
1 stop5h 31m
$371
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Sat 7/4
10:35 am-8:55 pm
2 stops10h 20m
Louisville Intl
Mon 7/6
3:35 pm-12:10 am
2 stops8h 35m
$416
Cheapest one-way
Quickest one-way
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Fri 7/17
5:35 am-12:30 pm
1 stop6h 55m
$204
PortlandLouisville
PWM - SDF
PWMSDF
Portland
Thu 7/16
1:12 pm-8:59 pm
1 stop7h 47m
$204
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Portland to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Louisville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Portland with our price prediction graph.
PWM-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Louisville
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 12, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Portland to Louisville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Portland to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsCorydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Other flights from Portland
Popular flights
Alternative routes for Portland to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Louisville by cabin class
Find flights from Portland to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Portland and Louisville flights
Browse other Portland and Louisville flight options. Last updated on June 12, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Portland to Louisville
Discover the top 3 airlines that operate flights from Portland to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$267 | Average$389 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$296 | Average$499 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$317 | Average$406 | FlexibilityNo cancel fee | On-time69% |