$145+ Cheap flights from San Antonio to Knoxville (SAT - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Antonio to KnoxvilleExplore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:10 am
SAT
- TYS
1 stop4h 55m
Southwest
Tue 11/102:45 pm
TYS
- SAT
1 stop6h 45m
Southwest
Deal found 6/8![Southwest logo]()
$230
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:25 pm
SAT
- TYS
1 stop6h 21m
Delta
Tue 10/275:57 pm
TYS
- SAT
1 stop7h 31m
Delta
Deal found 6/9![Delta logo]()
$237
This Gotogate deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Wed 7/228:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/8![Frontier logo]()
$239
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Wed 7/158:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/9![Frontier logo]()
$251
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:50 am
SAT
- TYS
1 stop4h 15m
Southwest
Sat 9/53:35 pm
TYS
- SAT
1 stop4h 05m
Southwest
Deal found 6/8![Southwest logo]()
$255
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:00 am
SAT
- TYS
1 stop6h 56m
American Airlines
Sat 9/54:00 pm
TYS
- SAT
1 stop5h 57m
American Airlines
Deal found 6/8![American Airlines logo]()
$268
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Mon 7/138:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/7![Frontier logo]()
$278
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am
SAT
- TYS
1 stop5h 15m
Southwest
Tue 9/157:00 am
TYS
- SAT
1 stop4h 20m
Southwest
Deal found 6/8![Southwest logo]()
$283
Best flights from San Antonio to KnoxvilleDiscover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:50 am
SAT
- TYS
1 stop4h 15m
Southwest
Wed 11/114:10 pm
TYS
- SAT
1 stop6h 25m
Southwest
Deal found 6/8![Southwest logo]()
$230
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am
SAT
- TYS
1 stop6h 07m
Delta
Tue 9/155:45 am
TYS
- SAT
1 stop4h 59m
Delta
Deal found 6/8![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:40 am
SAT
- TYS
1 stop6h 35m
Southwest
Tue 9/85:30 pm
TYS
- SAT
1 stop6h 35m
Southwest
Deal found 6/8![Southwest logo]()
$260
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:10 am
SAT
- TYS
2 stops8h 10m
Southwest
Mon 11/97:05 am
TYS
- SAT
2 stops8h 05m
Southwest
Deal found 6/8![Southwest logo]()
$300
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:10 am
SAT
- TYS
1 stop5h 15m
Southwest
Mon 8/312:05 pm
TYS
- SAT
1 stop5h 55m
Southwest
Deal found 6/4![Southwest logo]()
$329
Last-minute flights from San Antonio to KnoxvilleDiscover last-minute flight deals from San Antonio to Knoxville. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Knoxville. Data last updated June 9, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Fri 6/268:32 pm
TYS
- SAT
1 stop23h 24m
Frontier
Deal found 6/8![Frontier logo]()
$300
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:25 am
SAT
- TYS
1 stop6h 54m
Delta
Wed 7/85:40 am
TYS
- SAT
1 stop5h 03m
Delta
Deal found 6/8![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:30 am
SAT
- TYS
2 stops10h 30m
Southwest
Fri 7/106:40 am
TYS
- SAT
1 stop4h 40m
Southwest
Deal found 6/4![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:20 am
SAT
- TYS
1 stop9h 00m
Southwest
Tue 7/146:55 pm
TYS
- SAT
1 stop6h 00m
Southwest
Deal found 6/4![Southwest logo]()
$297
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Wed 7/158:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/9![Frontier logo]()
$251
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Mon 7/138:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/7![Frontier logo]()
$278
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:45 pm
SAT
- TYS
1 stop5h 50m
Southwest
Wed 7/157:10 am
TYS
- SAT
2 stops11h 25m
Southwest
Deal found 6/9![Southwest logo]()
$338
This Gotogate deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Wed 7/228:19 pm
TYS
- SAT
1 stop23h 25m
Frontier
Deal found 6/8![Frontier logo]()
$239
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:15 am
SAT
- TYS
1 stop5h 50m
Southwest
Wed 7/227:10 am
TYS
- SAT
2 stops11h 25m
Southwest
Deal found 6/8![Southwest logo]()
$302
One-way flights from San Antonio to KnoxvilleSearch for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 pm
SAT
- TYS
1 stop22h 45m
Frontier
Deal found 6/7![Frontier logo]()
$145
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:05 am
SAT
- TYS
1 stop7h 35m
Southwest
Deal found 6/4![Southwest logo]()
$165
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:15 pm
SAT
- TYS
1 stop7h 27m
Delta
Deal found 6/8![Delta logo]()
$175
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:16 pm
SAT
- TYS
1 stop4h 36m
Delta
Deal found 6/4![Delta logo]()
$187
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:00 am
SAT
- TYS
2 stops6h 25m
Southwest
Deal found 6/8![Southwest logo]()
$190
This Mytrip deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:51 pm
SAT
- TYS
1 stop22h 46m
Frontier
Deal found 6/7![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:25 am
SAT
- TYS
2 stops34h 14m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 pm
SAT
- TYS
2 stops26h 54m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$212
Find flight deals from San Antonio to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Southwest) |
One-way from | $145 (CheapOair) |
Popular in | April |
Cheapest in | January |
Average price | $397 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Wed 10/28
6:50 am-12:05 pm
1 stop4h 15m
Knoxville McGhee Tyson
Wed 11/11
4:10 pm-9:35 pm
1 stop6h 25m
$230
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sat 9/5
5:40 am-1:15 pm
1 stop6h 35m
Knoxville McGhee Tyson
Tue 9/8
5:30 pm-11:05 pm
1 stop6h 35m
$260
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 9/11
8:00 am-3:07 pm
1 stop6h 07m
Knoxville McGhee Tyson
Tue 9/15
5:45 am-9:44 am
1 stop4h 59m
$293
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 10/26
6:10 am-3:20 pm
2 stops8h 10m
Knoxville McGhee Tyson
Mon 11/9
7:05 am-2:10 pm
2 stops8h 05m
$300
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Thu 8/27
7:10 am-1:25 pm
1 stop5h 15m
Knoxville McGhee Tyson
Mon 8/31
2:05 pm-7:00 pm
1 stop5h 55m
$329
Cheapest one-way
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 9/21
11:50 am-7:55 pm
1 stop7h 05m
$145
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Thu 7/9
7:39 pm-7:24 pm
1 stop22h 45m
$145
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Thu 10/29
10:05 am-6:40 pm
1 stop7h 35m
$165
Quickest one-way
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 7/10
6:16 pm-11:52 pm
1 stop4h 36m
$187
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 7/13
4:15 pm-11:52 pm
1 stop6h 37m
$192
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
SAT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Knoxville
How far ahead should I book a flight from San Antonio to Knoxville?
Booking 72 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Antonio to Knoxville?
Currently, January is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $283). Flying from San Antonio to Knoxville in April is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 9, 2026.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
San Antonio and Knoxville flights
Browse other San Antonio and Knoxville flight options. Last updated on June 9, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Antonio to Knoxville
Discover the top 4 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$345 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$168 | Average$334 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$216 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$242 | Average$355 | FlexibilityNo cancel fee | On-time63% |