$395+ Cheap flights from La Crosse (LSE) to Florida Keys
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — EYW
Jul 15 — Jul 221
Round-trip
1 adult, Economy
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Find cheap flights from La Crosse to Florida Keys with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to Florida Keys
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Best
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One-way
Cheapest flights from La Crosse to Florida KeysExplore the most affordable flight options available from La Crosse to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
Explore the most affordable flight options available from La Crosse to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:01 pm
LSE
- MIA
1 stop5h 37m
American Airlines
Fri 7/107:21 pm
MIA
- LSE
1 stop5h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:50 am
LSE
- EYW
2 stops10h 57m
American Airlines
Sat 12/512:50 pm
EYW
- LSE
2 stops12h 02m
American Airlines
Deal found 6/10![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:37 am
LSE
- MIA
1 stop7h 41m
American Airlines
Wed 7/18:40 am
MIA
- LSE
2 stops9h 00m
American Airlines
Deal found 6/12![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:52 am
LSE
- MIA
1 stop5h 47m
American Airlines
Mon 6/227:31 pm
MIA
- LSE
1 stop5h 48m
American Airlines
Deal found 6/10![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:01 pm
LSE
- MIA
1 stop5h 47m
American Airlines
Sun 7/197:21 pm
MIA
- LSE
1 stop5h 38m
American Airlines
Deal found 6/14![American Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/512:01 pm
LSE
- EYW
1 stop26h 42m
American Airlines
Sat 7/1111:59 am
EYW
- LSE
2 stops13h 23m
American Airlines
Deal found 6/10![American Airlines logo]()
$842
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:42 am
LSE
- EYW
1 stop28h 24m
United Airlines
Sat 12/54:05 pm
EYW
- LSE
1 stop17h 51m
United Airlines
Deal found 6/10![United Airlines logo]()
$865
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:28 pm
LSE
- EYW
1 stop20h 56m
American Airlines
Wed 6/174:17 pm
EYW
- LSE
1 stop9h 02m
American Airlines
Deal found 6/14![American Airlines logo]()
$1,360
Best flights from La Crosse to Florida KeysDiscover carefully curated flight deals from La Crosse to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
Discover carefully curated flight deals from La Crosse to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:01 pm
LSE
- MIA
1 stop5h 37m
American Airlines
Fri 7/107:21 pm
MIA
- LSE
1 stop5h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:42 am
LSE
- EYW
1 stop28h 24m
United Airlines
Sat 12/54:05 pm
EYW
- LSE
1 stop17h 51m
United Airlines
Deal found 6/10![United Airlines logo]()
$865
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:37 am
LSE
- MIA
1 stop7h 41m
American Airlines
Wed 7/18:40 am
MIA
- LSE
2 stops9h 00m
American Airlines
Deal found 6/12![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1911:52 am
LSE
- MIA
1 stop5h 47m
American Airlines
Mon 6/227:31 pm
MIA
- LSE
1 stop5h 48m
American Airlines
Deal found 6/12![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:01 pm
LSE
- MIA
1 stop5h 47m
American Airlines
Sun 7/197:21 pm
MIA
- LSE
1 stop5h 38m
American Airlines
Deal found 6/14![American Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am
LSE
- EYW
2 stops14h 47m
American Airlines
Sat 12/51:17 pm
EYW
- LSE
1 stop11h 35m
American Airlines
Deal found 6/10![American Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/512:01 pm
LSE
- EYW
1 stop26h 42m
American Airlines
Sat 7/1111:59 am
EYW
- LSE
2 stops13h 23m
American Airlines
Deal found 6/11![American Airlines logo]()
$842
Last-minute flights from La Crosse to Florida KeysDiscover last-minute flight deals from La Crosse to Florida Keys. Data last updated June 15, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to Florida Keys. Data last updated June 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:28 pm
LSE
- EYW
1 stop20h 56m
American Airlines
Wed 6/174:17 pm
EYW
- LSE
1 stop9h 02m
American Airlines
Deal found 6/14![American Airlines logo]()
$1,360
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:52 am
LSE
- MIA
1 stop5h 47m
American Airlines
Mon 6/227:31 pm
MIA
- LSE
1 stop5h 48m
American Airlines
Deal found 6/10![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:37 am
LSE
- MIA
1 stop7h 41m
American Airlines
Wed 7/18:40 am
MIA
- LSE
2 stops9h 00m
American Airlines
Deal found 6/12![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:01 pm
LSE
- MIA
1 stop5h 37m
American Airlines
Fri 7/107:21 pm
MIA
- LSE
1 stop5h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/512:01 pm
LSE
- EYW
1 stop26h 42m
American Airlines
Sat 7/1111:59 am
EYW
- LSE
2 stops13h 23m
American Airlines
Deal found 6/10![American Airlines logo]()
$842
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:01 pm
LSE
- MIA
1 stop5h 47m
American Airlines
Sun 7/197:21 pm
MIA
- LSE
1 stop5h 38m
American Airlines
Deal found 6/14![American Airlines logo]()
$657
One-way flights from La Crosse to Florida KeysSearch for one-way flight options from La Crosse to Florida Keys. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
Search for one-way flight options from La Crosse to Florida Keys. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
LSE
- MIA
1 stop7h 08m
American Airlines
Deal found 6/13![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
LSE
- MIA
1 stop5h 43m
American Airlines
Deal found 6/14![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:57 am
LSE
- MIA
2 stops8h 54m
American Airlines
Deal found 6/13![American Airlines logo]()
$546
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:26 pm
LSE
- MIA
3 stops37h 58m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$581
Find flight deals from La Crosse to Florida Keys
Keep the following information in mind while searching for La Crosse to Florida Keys flight deals. Data was last updated June 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $395 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from La Crosse to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Sat 7/4
12:01 pm-6:38 pm
1 stop5h 37m
Miami
Fri 7/10
7:21 pm-11:59 pm
1 stop5h 38m
$395
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Sat 6/27
11:37 am-8:18 pm
1 stop7h 41m
Miami
Wed 7/1
8:40 am-4:40 pm
2 stops9h 00m
$501
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Fri 6/19
11:52 am-6:39 pm
1 stop5h 47m
Miami
Mon 6/22
7:31 pm-12:19 am
1 stop5h 48m
$550
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Mon 7/13
12:01 pm-6:48 pm
1 stop5h 47m
Miami
Sun 7/19
7:21 pm-11:59 pm
1 stop5h 38m
$657
La CrosseKey West
LSE - EYW
LSEEYW
La Crosse
Fri 11/27
6:00 am-9:47 pm
2 stops14h 47m
Key West
Sat 12/5
1:17 pm-11:52 pm
1 stop11h 35m
$775
La CrosseKey West
LSE - EYW
LSEEYW
La Crosse
Sun 7/5
12:01 pm-3:43 pm
1 stop26h 42m
Key West
Sat 7/11
11:59 am-12:22 am
2 stops13h 23m
$842
La CrosseKey West
LSE - EYW
LSEEYW
La Crosse
Fri 11/27
9:42 am-3:06 pm
1 stop28h 24m
Key West
Sat 12/5
4:05 pm-8:56 am
1 stop17h 51m
$865
Cheapest one-way
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Wed 8/5
6:00 am-2:08 pm
1 stop7h 08m
$460
Quickest one-way
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Thu 6/18
6:00 am-12:43 pm
1 stop5h 43m
$540
La CrosseMiami
LSE - MIA
LSEMIA
La Crosse
Thu 8/6
11:57 am-9:51 pm
2 stops8h 54m
$546
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from La Crosse to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from La Crosse with our price prediction graph.
LSE-MIA
LSE-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to Florida Keys
LSE-zzEOA
LSE-MIA
LSE-EYW
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated June 15, 2026.
See what other customers who have flown with American Airlines from La Crosse to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Boarding
7.5
Food
6.4
Crew
7.9
Entertainment
6.8
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Comfort
7.2
Boarding
7.5
Food
6.4
Crew
7.9
Entertainment
6.8
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for La Crosse to Florida Keys
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Complete your trip
Complete your trip to Florida Keys by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from La Crosse to Florida Keys, based on your preferred cabin class, be it economy, premium economy, business, or first class.
La Crosse and Florida Keys flights
Browse other La Crosse and Florida Keys flight options. Last updated on June 15, 2026.
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La Crosse to Florida Keys flights
Consider these flights traveling from La Crosse to Florida Keys.
Top airline flying from La Crosse to Florida Keys
Discover the top airline that operate flights from La Crosse to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$481 | Average$585 | FlexibilityNo cancel fee | On-time71% |