$502+ Cheap flights from Des Moines (DSM) to Saint Croix
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STX
Oct 28 — Nov 41
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Saint Croix with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Saint Croix
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One-way
Cheapest flights from Des Moines to Saint CroixExplore the most affordable flight options available from Des Moines to Saint Croix. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
Explore the most affordable flight options available from Des Moines to Saint Croix. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:23 am -
2 stops12h 57m
Mon 11/169:00 am -
2 stops17h 26m
Deal found 9/25![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:31 pm -
2 stops19h 31m
Wed 10/142:38 pm -
2 stops19h 18m
Deal found 9/25![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:12 pm -
2 stops20h 36m
Sat 10/172:38 pm -
1 stop9h 58m
Deal found 9/27![American Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:05 am -
2 stops11h 33m
Mon 11/169:59 am -
3 stops15h 00m
Deal found 9/25![United Airlines logo]()
$1,190
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
2 stops29h 30m
Fri 10/93:14 pm -
2 stops54h 47m
Deal found 9/25![United Airlines logo]()
$3,242
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
2 stops12h 38m
Sat 10/179:59 am -
3 stops14h 36m
Deal found 9/27![United Airlines logo]()
$11,705
Best flights from Des Moines to Saint CroixDiscover carefully curated flight deals from Des Moines to Saint Croix that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
Discover carefully curated flight deals from Des Moines to Saint Croix that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/275:12 am -
1 stop15h 39m
Sun 2/75:43 pm -
1 stop7h 57m
Deal found 9/23![American Airlines logo]()
$503
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/175:45 am -
1 stop6h 35m
Thu 3/252:25 pm -
1 stop9h 04m
Deal found 9/25![Delta logo]()
$706
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/187:00 am -
1 stop6h 48m
Mon 3/225:12 pm -
2 stops21h 18m
Deal found 9/25![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:30 am -
1 stop8h 28m
Wed 10/145:08 pm -
2 stops16h 48m
Deal found 9/25![American Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:14 pm -
2 stops23h 34m
Sat 10/175:08 pm -
2 stops20h 27m
Deal found 9/27![American Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/142:02 pm -
2 stops22h 15m
Thu 3/253:38 pm -
2 stops18h 38m
Deal found 9/25![American Airlines logo]()
$720
Last-minute flights from Des Moines to Saint CroixDiscover last-minute flight deals from Des Moines to Saint Croix. Data last updated September 28, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Saint Croix. Data last updated September 28, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
2 stops29h 30m
Fri 10/93:14 pm -
2 stops54h 47m
Deal found 9/25![United Airlines logo]()
$3,242
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:31 pm -
2 stops19h 31m
Wed 10/142:38 pm -
2 stops19h 18m
Deal found 9/25![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:12 pm -
2 stops20h 36m
Sat 10/172:38 pm -
1 stop9h 58m
Deal found 9/27![American Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
2 stops12h 38m
Sat 10/179:59 am -
3 stops14h 36m
Deal found 9/27![United Airlines logo]()
$11,705
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:31 pm -
2 stops19h 31m
Sun 2/144:31 pm -
2 stops22h 59m
Deal found 9/28![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:31 pm -
3 stops17h 17m
Thu 11/59:00 am -
2 stops16h 05m
Deal found 9/28![American Airlines logo]()
$782
One-way flights from Des Moines to Saint CroixSearch for one-way flight options from Des Moines to Saint Croix. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
Search for one-way flight options from Des Moines to Saint Croix. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:18 pm -
2 stops18h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![American Airlines logo]()
$515
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:00 am -
3 stops34h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$636
Find flight deals from Des Moines to Saint Croix
Keep the following information in mind while searching for Des Moines to Saint Croix flight deals. Data was last updated September 28, 2026.
Round-trip from | $502 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Saint Croix that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
Use the filters below to find and compare flights from Des Moines to Saint Croix that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Wed 1/27
5:12 am-10:51 pm
1 stop15h 39m
Christiansted Henry Rohlsen
Sun 2/7
5:43 pm-11:40 pm
1 stop7h 57m
$503
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Sun 12/20
8:18 pm-4:29 pm
2 stops18h 11m
Christiansted Henry Rohlsen
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$515
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Sun 12/20
7:00 am-7:38 pm
3 stops34h 38m
Christiansted Henry Rohlsen
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$636
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Thu 3/18
7:00 am-2:48 pm
1 stop6h 48m
Christiansted Henry Rohlsen
Mon 3/22
5:12 pm-1:30 pm
2 stops21h 18m
$642
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Sat 10/10
6:30 am-3:58 pm
1 stop8h 28m
Christiansted Henry Rohlsen
Wed 10/14
5:08 pm-8:56 am
2 stops16h 48m
$644
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Tue 10/13
1:14 pm-1:48 pm
2 stops23h 34m
Christiansted Henry Rohlsen
Sat 10/17
5:08 pm-12:35 pm
2 stops20h 27m
$644
Quickest round-trip
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Wed 3/17
5:45 am-1:20 pm
1 stop6h 35m
Christiansted Henry Rohlsen
Thu 3/25
2:25 pm-10:29 pm
1 stop9h 04m
$706
Des MoinesChristiansted
DSM Des Moines - STX Christiansted Henry Rohlsen
DSMSTX
Des Moines
Sun 3/14
2:02 pm-1:17 pm
2 stops22h 15m
Christiansted Henry Rohlsen
Thu 3/25
3:38 pm-9:16 am
2 stops18h 38m
$720
Sorted by cheapest first
Best time to book a flight from Des Moines to Saint Croix
Have a flexible travel schedule? Discover the best time to fly to Saint Croix from Des Moines with our price prediction graph.
DSM-STX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Saint Croix
DSM-VISC
DSM-STX
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Saint Croix
Get insights into the airlines that provide service to Saint Croix. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Saint Croix. Reviews last updated September 28, 2026.
Read through reviews of airlines operating flights from Des Moines to Saint Croix, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Crew
7.9
Comfort
7.2
Food
6.4
Overall
7.0
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Boarding
7.4
Crew
7.9
Comfort
7.2
Food
6.4
Overall
7.0
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Saint Croix. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Des Moines and Saint Croix flights
Browse other Des Moines and Saint Croix flight options. Last updated on September 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Des Moines to Saint Croix
Discover the top airline that operate flights from Des Moines to Saint Croix. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$462 | Average$634 | FlexibilityNo cancel fee | On-time71% |