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$310+ Cheap flights from St. Louis (STL) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheap flight deals from St. Louis to Spain

Keep the following information in mind while searching for St. Louis to Spain flight deals. Data was last updated November 5, 2025.

Round-trip from

$429
(Delta)

One-way from

$310
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$669
From Lambert-St Louis to Spain
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One-way flight from Lambert-St Louis to Spain
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Highest demand for flights based on searches. 24% potential increase in price ($295 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Spain

Cheapest flights from St. Louis to Spain
Explore the most affordable flight options available from St. Louis to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This KLM deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:30 pmSTL - MAD
1 stop32h 30mKLM
Wed 12/1711:15 amMAD - STL
1 stop14h 18mKLM
Deal found 11/4$429
This KLM deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:39 amSTL - MAD
1 stop14h 36mKLM
Tue 12/1610:00 amMAD - STL
1 stop13h 35mKLM
Deal found 11/3$438
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1012:31 pmSTL - BCN
2 stops16h 29mLufthansa
Wed 11/266:50 amBCN - STL
1 stop14h 05mLufthansa
Deal found 11/3$439
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:02 pmSTL - MAD
2 stops15h 38mDelta
Wed 12/1710:00 amMAD - STL
2 stops17h 47mDelta
Deal found 11/4$448
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:02 pmSTL - MAD
2 stops17h 08mDelta
Tue 12/1610:00 amMAD - STL
1 stop13h 35mDelta
Deal found 11/3$457
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:35 pmSTL - BCN
2 stops37h 00mUnited Airlines
Thu 12/111:35 pmBCN - STL
2 stops34h 28mUnited Airlines
Deal found 11/5$461
This KLM deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:12 pmSTL - BCN
1 stop32h 28mKLM
Thu 12/1110:55 amBCN - STL
1 stop17h 07mKLM
Deal found 11/4$464
This United deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:31 pmSTL - BCN
1 stop32h 29mMultiple Airlines
Tue 11/111:35 pmBCN - STL
2 stops31h 49mMultiple Airlines
Deal found 11/4$466
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/43:14 pmSTL - BCN
2 stops16h 01mUnited Airlines
Tue 11/111:35 pmBCN - STL
2 stops31h 49mUnited Airlines
Deal found 11/4$469
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1012:31 pmSTL - BCN
2 stops13h 29mUnited Airlines
Wed 11/2610:30 amBCN - STL
2 stops18h 10mUnited Airlines
Deal found 11/3$473
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:24 pmSTL - BCN
1 stop12h 46mUnited Airlines
Wed 11/196:50 amBCN - STL
1 stop14h 05mUnited Airlines
Deal found 11/3$476
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:42 pmSTL - MAD
2 stops30h 18mUnited Airlines
Mon 12/86:00 amMAD - STL
2 stops23h 45mUnited Airlines
Deal found 11/5$478

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from St. Louis to Spain that are best for you.

Fly from

St. Louis

Fly to

Spain

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 12/1

11:39 am-9:15 am

1 stop14h 36m

Madrid Barajas

Tue 12/16

10:00 am-4:35 pm

1 stop13h 35m

$438

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Mon 11/10

12:31 pm-12:00 pm

2 stops16h 29m

Barcelona-El Prat

Wed 11/26

6:50 am-1:55 pm

1 stop14h 05m

$439

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 12/1

7:02 pm-5:40 pm

2 stops15h 38m

Madrid Barajas

Wed 12/17

10:00 am-8:47 pm

2 stops17h 47m

$448

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Thu 12/4

8:30 am-8:20 am

1 stop16h 50m

Barcelona-El Prat

Thu 12/11

1:35 pm-10:45 pm

2 stops40h 10m

$461

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Mon 2/2

8:45 am-9:35 am

2 stops17h 50m

Barcelona-El Prat

Mon 2/16

1:35 pm-10:00 pm

2 stops39h 25m

$461

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Thu 12/4

5:12 pm-8:40 am

1 stop32h 28m

Barcelona-El Prat

Thu 12/11

10:55 am-9:02 pm

1 stop17h 07m

$464

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Sat 1/24

8:30 am-9:00 am

2 stops17h 30m

Barcelona-El Prat

Sat 1/31

1:35 pm-2:30 pm

2 stops31h 55m

$465

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Mon 11/10

12:31 pm-9:00 am

2 stops13h 29m

Barcelona-El Prat

Wed 11/26

10:30 am-9:40 pm

2 stops18h 10m

$473

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 12/3

6:42 pm-9:15 am

2 stops31h 33m

Madrid Barajas

Mon 12/8

6:00 am-10:45 pm

2 stops23h 45m

$478

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 12/3

5:28 pm-9:15 am

1 stop32h 47m

Madrid Barajas

Mon 12/8

10:00 am-4:35 pm

1 stop13h 35m

$479

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 57 results
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Best time to book a flight from St. Louis to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Spain

What is the cheapest month to book a flight from St. Louis to Spain?

Currently, November is the cheapest month in which you can book a flight from St. Louis to Spain (average of $534). Flying from St. Louis to Spain in June is currently the most expensive (average of $907). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to ES?

Find hourly flight availability from St. Louis to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 8% on flights from St. Louis to Spain by exploring options for tickets at noon.

What is the cheapest day to fly from St. Louis to Spain?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their St. Louis to Spain flight should consider departing on Wednesday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated November 5, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Air Canada from St. Louis to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,004 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,004 reviews
United Airlines
7.4
Good
9,004 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,042 reviews
United Airlines
7.4
Good
9,004 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
Air Canada
7.1
Good
10,410 reviews
United Airlines
7.4
Good
9,004 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
Iberia
7.0
Good
3,007 reviews
United Airlines
7.4
Good
9,004 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
British Airways
6.7
Okay
7,496 reviews
United Airlines
7.4
Good
9,004 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Spain?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Spain. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How long is the flight from St. Louis to Spain?

    For as low as $438, KLM can have you in Spain from St. Louis in 14h 36m. St. Louis and Spain are separated by a distance of 4414 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from St. Louis to Spain one-way?

    One-way options have recently been found by users for as low as $371 on Lufthansa. Other airlines that offer cheap prices include Air Canada from $399 and Delta from $452 one-way.

  • What are the most popular routes from St. Louis to Spain?

    Most travelers choose Lambert-St Louis - Barcelona-El Prat, Lambert-St Louis - Madrid Barajas or Lambert-St Louis - Sevilla when deciding on the best route from St. Louis to Spain.

  • Can I find deals for flights from St. Louis to Spain that include hotel bookings?

    Yes. In addition to deals on St. Louis to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Spain.

  • Can I find deals for business class flights from St. Louis to Spain?

    Yes. Cheapflights offers flight deals from St. Louis to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Spain?

    Currently, November is the cheapest month in which you can book a flight from St. Louis to Spain (average of $534). Flying from St. Louis to Spain in June is currently the most expensive (average of $907). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from St. Louis to Spain

Discover the top 8 airlines that operate flights from St. Louis to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$524Average$1,155FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$546Average$833FlexibilityNo cancel feeOn-time70%
DeltaCheapest$552Average$899FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$578Average$976FlexibilityNo cancel feeOn-time69%
IberiaCheapest$586Average$931FlexibilityNo cancel feeOn-time77%
KLMCheapest$590Average$745FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$624Average$1,093FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$636Average$1,080FlexibilityNo cancel feeOn-time71%

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