HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spain

$650+ Cheap flights from Columbia, MO (COU) to Spain

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MAD
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to Spain with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to Spain

Cheapest flights from Columbia to Spain
Explore the most affordable flight options available from Columbia to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:10 pm
COU
-
MAD
2 stops32h 40m
United Airlines
Thu 5/146:05 am
MAD
-
COU
2 stops22h 53m
United Airlines
Deal found 2/2$650
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:00 am
COU
-
MAD
2 stops18h 15m
United Airlines
Sun 3/15:55 am
MAD
-
COU
2 stops22h 38m
United Airlines
Deal found 2/3$682
This Finnair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
COU
-
MAD
1 stop18h 55m
Multiple Airlines
Thu 5/1411:35 am
MAD
-
COU
1 stop16h 55m
Multiple Airlines
Deal found 2/2$714
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:28 pm
COU
-
MAD
2 stops14h 02m
American Airlines
Thu 5/1411:35 am
MAD
-
COU
1 stop16h 55m
American Airlines
Deal found 2/2$718

Find flight deals from Columbia to Spain

Keep the following information in mind while searching for Columbia to Spain flight deals. Data was last updated February 4, 2026.

Round-trip from

$650
(United Airlines)
From Columbia Regional to Spain
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Columbia to Spain that are best for you.

Fly from

Columbia

Fly to

Spain

Route

Depart

Return

Price

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Thu 5/7

3:10 pm-6:50 am

2 stops32h 40m

Madrid Barajas

Thu 5/14

6:05 am-9:58 pm

2 stops22h 53m

$650

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Wed 2/25

8:00 am-9:15 am

2 stops18h 15m

Madrid Barajas

Sun 3/1

5:55 am-9:33 pm

2 stops22h 38m

$682

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Thu 5/7

6:00 am-7:55 am

1 stop18h 55m

Madrid Barajas

Thu 5/14

11:35 am-9:30 pm

1 stop16h 55m

$714

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Thu 5/7

4:28 pm-1:30 pm

2 stops14h 02m

Madrid Barajas

Thu 5/14

11:35 am-9:30 pm

1 stop16h 55m

$718

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Best time to book a flight from Columbia to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Spain
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated February 4, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to Spain have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,236 reviews

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,236 reviews
United Airlines
7.4
Good
9,236 reviews

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,222 reviews
United Airlines
7.4
Good
9,236 reviews

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Columbia to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Spain?

    Columbia Regional (COU) is the airport you will fly out of if you book a flight from Columbia to Spain. It is only a 11.1 mi journey to Columbia Regional (COU) from Columbia’s city center.

  • How long is the flight from Columbia, Missouri to Spain?

    Airlines like United Airlines fly from Columbia, Missouri to Spain in about 32h 40m. The time it takes to get you to your destination can typically vary by up to . The distance between Columbia, Missouri and Spain is about 4495 mi.

  • Can I find deals for flights from Columbia to Spain that include hotel bookings?

    Yes. In addition to deals on Columbia to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Spain.

  • Can I find deals for business class flights from Columbia to Spain?

    Yes. Cheapflights offers flight deals from Columbia to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to Spain

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Heathrow flights
Kansas City to Heathrow flights
Kansas City to Dublin flights
St. Louis to Gatwick flights
St. Louis to Frankfurt flights
St. Louis to London City flights
St. Louis to Leonardo da Vinci/Fiumicino flights
St. Louis to Dublin flights
St. Louis to Stansted flights
St. Louis to Athens flights
Kansas City to Gatwick flights
St. Louis to Charles de Gaulle flights
Kansas City to Leonardo da Vinci/Fiumicino flights
St. Louis to Orly flights
Kansas City to Athens flights
Kansas City to Charles de Gaulle flights
St. Louis to Malpensa flights
St. Louis to Lisbon flights
St. Louis to Madrid flights
St. Louis to Barcelona-El Prat flights
St. Louis to Edinburgh flights
St. Louis to Linate flights
Kansas City to Vicenza flights
St. Louis to Zurich flights
Kansas City to London City flights
Kansas City to Amsterdam flights
St. Louis to Istanbul flights
Kansas City to Edinburgh flights
Kansas City to Stansted flights
Kansas City to Frankfurt flights
Springfield to Heathrow flights
Kansas City to Barcelona-El Prat flights
Kansas City to Lisbon flights
St. Louis to Keflavik Intl flights
Kansas City to Madrid flights
Springfield to Istanbul flights
Kansas City to Frederic Chopin flights
St. Louis to Amsterdam flights
St. Louis to Florence flights
St. Louis to Sabiha Gokcen flights
Kansas City to Zurich flights
Kansas City to Orly flights
Kansas City to Malpensa flights
St. Louis to Sarajevo flights
Kansas City to Geneva flights
St. Louis to Oslo Gardermoen flights
Springfield to Edinburgh flights
St. Louis to Glasgow Intl flights
St. Louis to Munich flights
Kansas City to Keflavik Intl flights

Top 2 airlines flying from Columbia to Spain

Discover the top 2 airlines that operate flights from Columbia to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$490Average$653FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$677Average$1,126FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights