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$573+ Cheap flights from Columbia, MO (COU) to Spain

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MAD
Mar 24 — Mar 311
Tue 3/24
Tue 3/31
1 adult, Economy
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Cheap flight deals from Columbia to Spain

Cheapest flights from Columbia to Spain
Explore the most affordable flight options available from Columbia to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.

This British Airways deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:28 pm
COU
-
MAD
2 stops16h 22m
Multiple Airlines
Tue 4/2811:45 am
MAD
-
COU
1 stop16h 45m
Multiple Airlines
Deal found 2/22$573
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:00 am
COU
-
MAD
2 stops18h 50m
United Airlines
Tue 4/285:55 am
MAD
-
COU
2 stops23h 01m
United Airlines
Deal found 2/22$580
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:00 am
COU
-
MAD
2 stops19h 15m
United Airlines
Mon 3/1611:15 am
MAD
-
COU
2 stops39h 05m
United Airlines
Deal found 2/19$690
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:00 am
COU
-
MAD
2 stops39h 50m
United Airlines
Wed 5/61:30 pm
MAD
-
COU
2 stops39h 28m
United Airlines
Deal found 2/22$702
This British Airways deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:28 pm
COU
-
MAD
2 stops16h 22m
Multiple Airlines
Wed 5/611:45 am
MAD
-
COU
1 stop16h 45m
Multiple Airlines
Deal found 2/22$711
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
-
MAD
2 stops15h 00m
United Airlines
Sun 3/111:15 am
MAD
-
COU
2 stops17h 18m
United Airlines
Deal found 2/18$717
This Finnair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:08 am
COU
-
MAD
1 stop16h 42m
Multiple Airlines
Mon 3/1612:00 pm
MAD
-
COU
1 stop14h 19m
Multiple Airlines
Deal found 2/19$765
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:08 am
COU
-
MAD
2 stops15h 47m
American Airlines
Mon 3/1611:25 am
MAD
-
COU
1 stop17h 11m
American Airlines
Deal found 2/19$885
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:00 am
COU
-
MAD
2 stops18h 50m
United Airlines
Wed 7/15:55 am
MAD
-
COU
2 stops24h 11m
United Airlines
Deal found 2/21$995

Find flight deals from Columbia to Spain

Keep the following information in mind while searching for Columbia to Spain flight deals. Data was last updated February 22, 2026.

Round-trip from

$645
(United Airlines)
From Columbia Regional to Spain
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Columbia to Spain that are best for you.

Fly from

Columbia

Fly to

Spain

Route

Depart

Return

Price

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Mon 3/9

8:00 am-9:15 am

2 stops19h 15m

Madrid Barajas

Mon 3/16

11:15 am-8:20 pm

2 stops39h 05m

$690

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Fri 4/24

4:28 pm-3:50 pm

2 stops16h 22m

Madrid Barajas

Wed 5/6

11:45 am-9:30 pm

1 stop16h 45m

$711

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Mon 3/9

10:08 am-8:50 am

1 stop16h 42m

Madrid Barajas

Mon 3/16

12:00 pm-8:19 pm

1 stop14h 19m

$765

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Mon 3/9

10:08 am-7:55 am

2 stops15h 47m

Madrid Barajas

Mon 3/16

11:25 am-10:36 pm

1 stop17h 11m

$885

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Wed 5/27

5:00 am-6:50 am

2 stops18h 50m

Madrid Barajas

Wed 7/1

5:55 am-11:06 pm

2 stops24h 11m

$995

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Wed 5/27

6:27 pm-1:30 pm

1 stop12h 03m

Madrid Barajas

Wed 7/1

1:00 pm-10:46 pm

1 stop16h 46m

$1,117

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Wed 3/18

11:15 am-9:15 am

2 stops16h 00m

Madrid Barajas

Sat 3/21

8:25 am-9:33 pm

2 stops43h 08m

$1,666

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Mon 4/6

6:00 am-8:20 am

1 stop19h 20m

Madrid Barajas

Tue 4/7

11:45 am-9:30 pm

1 stop16h 45m

$5,520

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Best time to book a flight from Columbia to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Spain
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated February 22, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to Spain have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,341 reviews

Food

6.6

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,341 reviews
United Airlines
7.4
Good
9,341 reviews

Food

6.6

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,338 reviews
United Airlines
7.4
Good
9,341 reviews

Food

6.6

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Columbia to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Spain?

    Columbia Regional (COU) is the airport you will fly out of if you book a flight from Columbia to Spain. It is only a 11.1 mi journey to Columbia Regional (COU) from Columbia’s city center.

  • How long is the flight from Columbia, Missouri to Spain?

    Airlines like United Airlines and American Airlines fly from Columbia, Missouri to Spain in about 15h 47m. The time it takes to get you to your destination can typically vary by up to 3h 28m. The distance between Columbia, Missouri and Spain is about 4495 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Columbia to Spain that include hotel bookings?

    Yes. In addition to deals on Columbia to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Spain.

  • Can I find deals for business class flights from Columbia to Spain?

    Yes. Cheapflights offers flight deals from Columbia to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Columbia to Spain

Discover the top 2 airlines that operate flights from Columbia to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$490Average$653FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$677Average$1,096FlexibilityNo cancel feeOn-time71%

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