$720+ Cheap flights from Columbia, MO (COU) to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MAD
Oct 19 — Oct 261
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to Spain
Keep the following information in mind while searching for Columbia to Spain flight deals. Data was last updated September 19, 2025.
Round-trip from | $720 (American Airlines) |
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Find flight deals from Columbia to Spain
Cheapest flights from Columbia to SpainExplore the most affordable flight options available from Columbia to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.
Explore the most affordable flight options available from Columbia to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:41 amCOU - MAD
2 stops23h 54mAmerican Airlines
Tue 11/188:50 pmMAD - COU
2 stops32h 05mAmerican Airlines
Deal found 9/17![American Airlines logo]()
$720
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Columbia to Spain that are best for you.
Fly from
Columbia
Fly to
Spain
Route
Depart
Return
Price
ColumbiaMadrid
COU - MAD
COUMAD
Columbia Regional
Fri 11/14
11:41 am-6:35 pm
2 stops23h 54m
Madrid Barajas
Tue 11/18
8:50 pm-9:55 pm
2 stops32h 05m
$720
Best time to book a flight from Columbia to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbia to Spain
What is the cheapest time of day to fly from COU to ES?
Find hourly flight availability from Columbia to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2025.
When flying from Columbia, Missouri to Spain, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.