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South Padre Island

$339+ Cheap flights from Missouri to South Padre Island, TX

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MFE
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Missouri to South Padre Island

Cheapest flights from Missouri to South Padre Island
Explore the most affordable flight options available from Missouri to South Padre Island. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am
STL
-
BRO
1 stop4h 25m
American Airlines
Mon 9/146:43 pm
BRO
-
STL
1 stop4h 58m
American Airlines
Deal found 4/28$339
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:39 am
MCI
-
BRO
1 stop4h 41m
American Airlines
Wed 5/135:40 am
BRO
-
MCI
1 stop4h 33m
American Airlines
Deal found 4/24$369
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:27 pm
STL
-
BRO
1 stop6h 44m
American Airlines
Wed 5/1310:44 am
BRO
-
STL
1 stop6h 37m
American Airlines
Deal found 4/24$369
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:19 pm
STL
-
BRO
1 stop15h 36m
Multiple Airlines
Fri 6/128:35 am
BRO
-
STL
1 stop15h 34m
Multiple Airlines
Deal found 4/26$379
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:27 pm
STL
-
BRO
2 stops38h 28m
Multiple Airlines
Fri 6/128:35 am
BRO
-
STL
1 stop15h 34m
Multiple Airlines
Deal found 4/26$392
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:19 pm
STL
-
BRO
1 stop15h 36m
Multiple Airlines
Mon 6/88:35 am
BRO
-
STL
1 stop15h 22m
Multiple Airlines
Deal found 4/27$395
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:29 am
STL
-
BRO
1 stop4h 45m
American Airlines
Sun 6/76:42 pm
BRO
-
STL
1 stop5h 17m
American Airlines
Deal found 4/27$399
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:35 am
STL
-
BRO
2 stops11h 37m
American Airlines
Sun 6/76:42 pm
BRO
-
STL
1 stop5h 17m
American Airlines
Deal found 4/27$404
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:24 pm
STL
-
BRO
1 stop4h 59m
American Airlines
Mon 6/86:42 pm
BRO
-
STL
1 stop5h 17m
American Airlines
Deal found 4/27$417
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:24 pm
STL
-
BRO
1 stop4h 59m
American Airlines
Tue 6/96:42 pm
BRO
-
STL
1 stop5h 17m
American Airlines
Deal found 4/26$419
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:50 pm
MCI
-
BRO
2 stops8h 09m
United Airlines
Wed 5/137:20 am
BRO
-
MCI
2 stops8h 55m
United Airlines
Deal found 4/24$424
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:15 pm
MCI
-
BRO
1 stop5h 44m
United Airlines
Fri 5/155:17 pm
BRO
-
MCI
1 stop5h 12m
United Airlines
Deal found 4/26$509

Find flight deals from Missouri to South Padre Island

Keep the following information in mind while searching for Missouri to South Padre Island flight deals. Data was last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(American Airlines)

Popular in

December

Cheapest in

February

Average price

$428
Provider with most accurate pricing for Lambert-St Louis-Brownsville South Padre Is. Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Brownsville South Padre Is. Intl flights.
Search Deals
From Missouri to South Padre Island
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to South Padre Island that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Missouri to South Padre Island that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Thu 9/10

7:44 am-6:13 pm

2 stops10h 29m

Brownsville South Padre Is. Intl

Mon 9/14

6:43 pm-11:41 pm

1 stop4h 58m

$344
Quickest round-trip

Kansas CityBrownsville

MCI - BRO

MCIBRO

Kansas City

Sat 5/9

9:39 am-2:20 pm

1 stop4h 41m

Brownsville South Padre Is. Intl

Wed 5/13

5:40 am-10:13 am

1 stop4h 33m

$369

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Sat 5/9

12:27 pm-7:11 pm

1 stop6h 44m

Brownsville South Padre Is. Intl

Wed 5/13

10:44 am-5:21 pm

1 stop6h 37m

$369

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Wed 6/10

8:35 am-3:57 pm

1 stop7h 22m

Brownsville South Padre Is. Intl

Sat 6/13

4:44 pm-10:45 pm

1 stop6h 01m

$419

Kansas CityBrownsville

MCI - BRO

MCIBRO

Kansas City

Sat 5/9

1:50 pm-9:59 pm

2 stops8h 09m

Brownsville South Padre Is. Intl

Wed 5/13

7:20 am-4:15 pm

2 stops8h 55m

$424

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Wed 6/3

6:00 am-6:37 pm

2 stops12h 37m

Brownsville South Padre Is. Intl

Sat 6/6

4:44 pm-10:45 pm

1 stop6h 01m

$424

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Wed 5/13

8:55 am-7:11 pm

2 stops10h 16m

Brownsville South Padre Is. Intl

Sun 5/17

5:40 am-11:27 am

1 stop5h 47m

$439

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Wed 6/3

6:35 am-6:12 pm

2 stops11h 37m

Brownsville South Padre Is. Intl

Sat 6/6

5:30 am-1:56 pm

2 stops8h 26m

$445

St. LouisBrownsville

STL - BRO

STLBRO

Lambert-St Louis

Thu 6/11

8:35 am-3:57 pm

1 stop7h 22m

Brownsville South Padre Is. Intl

Sat 6/13

4:44 pm-10:45 pm

1 stop6h 01m

$479

Kansas CityBrownsville

MCI - BRO

MCIBRO

Kansas City

Mon 5/11

4:15 pm-9:59 pm

1 stop5h 44m

Brownsville South Padre Is. Intl

Fri 5/15

5:17 pm-10:29 pm

1 stop5h 12m

$509

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 12 resultsSorted by cheapest first
1
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Best time to book a flight from Missouri to South Padre Island

Have a flexible travel schedule? Discover the best time to fly to South Padre Island from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to South Padre Island

How much does it cost to fly round-trip from Missouri to South Padre Island?

Related info for your journey

Find useful and relevant information for your journey from Missouri to South Padre Island. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to South Padre Island?

    Airlines like American Airlines and United Airlines fly from Missouri to South Padre Island in about 8h 09m. The time it takes to get you to your destination can typically vary by up to 2h 20m. The distance between Missouri and South Padre Island is about 938 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missouri to South Padre Island that include hotel bookings?

    Yes. In addition to deals on Missouri to South Padre Island flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to South Padre Island?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to South Padre Island.

  • Can I find deals for business class flights from Missouri to South Padre Island?

    Yes. Cheapflights offers flight deals from Missouri to South Padre Island by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to South Padre Island

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to South Padre Island

Discover the top 3 airlines that operate flights from Missouri to South Padre Island. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$412FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$199Average$355FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$216Average$341FlexibilityNo cancel feeOn-time69%

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