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South Carolina

$165+ Cheap flights from Missoula (MSO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Missoula to South Carolina

Cheapest flights from Missoula to South Carolina
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/102:37 pm
MSO
-
CLT
1 stop6h 22m
United Airlines
Sat 2/1410:42 am
CLT
-
MSO
2 stops13h 15m
United Airlines
Deal found 1/26$364
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:00 am
MSO
-
CLT
1 stop9h 00m
Delta
Sat 2/145:05 pm
CLT
-
MSO
1 stop8h 25m
Delta
Deal found 1/26$369
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:34 pm
MSO
-
CLT
1 stop6h 14m
United Airlines
Tue 3/38:11 am
CLT
-
MSO
1 stop7h 21m
United Airlines
Deal found 1/25$399
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/112:35 pm
MSO
-
CLT
1 stop6h 03m
United Airlines
Mon 3/168:07 am
CLT
-
MSO
1 stop7h 26m
United Airlines
Deal found 1/25$424
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:32 am
MSO
-
CLT
2 stops11h 25m
Delta
Mon 3/1612:45 pm
CLT
-
MSO
2 stops13h 39m
Delta
Deal found 1/25$471
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:00 am
MSO
-
CLT
1 stop7h 16m
United Airlines
Fri 1/307:44 pm
CLT
-
MSO
2 stops28h 07m
United Airlines
Deal found 1/24$874
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/312:46 pm
MSO
-
MYR
2 stops19h 55m
United Airlines
Tue 2/31:25 pm
MYR
-
MSO
2 stops28h 32m
United Airlines
Deal found 1/24$1,077

Find flight deals from Missoula to South Carolina

Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$364
(United Airlines)

One-way from

$165
(Kiwi.com)
Provider with most accurate pricing for Missoula Johnson-Bell Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Missoula Johnson-Bell Field-Myrtle Beach Intl flights.
Search Deals
From Missoula Johnson-Bell Field to South Carolina
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One-way flight from Missoula Johnson-Bell Field to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.

Fly from

Missoula

Fly to

South Carolina

Route

Depart

Return

Price

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Tue 2/10

6:00 am-9:37 pm

2 stops13h 37m

Charlotte Douglas

Sat 2/14

10:42 am-9:57 pm

2 stops13h 15m

$370

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Sat 2/28

2:34 pm-10:48 pm

1 stop6h 14m

Charlotte Douglas

Tue 3/3

8:11 am-4:09 pm

1 stop9h 58m

$399

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 3/11

2:35 pm-10:38 pm

1 stop6h 03m

Charlotte Douglas

Mon 3/16

8:07 am-4:08 pm

1 stop10h 01m

$424

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 3/11

8:32 am-9:57 pm

2 stops11h 25m

Charlotte Douglas

Mon 3/16

12:45 pm-12:24 am

2 stops13h 39m

$471

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Fri 2/27

4:04 pm-5:48 pm

2 stops23h 44m

$165

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Fri 2/27

7:30 am-5:57 pm

1 stop8h 27m

$241

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Thu 2/19

7:30 am-5:57 pm

1 stop8h 27m

$241

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Tue 2/10

7:55 am-4:28 pm

1 stop6h 33m

$271

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Tue 2/10

2:03 pm-9:39 pm

3 stops29h 36m

$632

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Best time to book a flight from Missoula to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to South Carolina

What is the cheapest month to book a flight from Missoula to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Missoula to South Carolina (average of $308). Flying from Missoula to South Carolina in November is currently the most expensive (average of $678). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSO to SC?

Find hourly flight availability from Missoula to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 26, 2026.

When flying from Missoula to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 66% versus a flight in the morning.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 26, 2026.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,199 reviews

Food

6.6

Entertainment

7.1

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,199 reviews
United Airlines
7.4
Good
9,199 reviews

Food

6.6

Entertainment

7.1

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,189 reviews
United Airlines
7.4
Good
9,199 reviews

Food

6.6

Entertainment

7.1

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Missoula to South Carolina?

    Missoula Johnson-Bell Field (MSO), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Missoula to South Carolina.

  • How long is the flight from Missoula to South Carolina?

    Airlines like United Airlines fly from Missoula to South Carolina in about 13h 37m. The time it takes to get you to your destination can typically vary by up to . Missoula and South Carolina are separated by a distance of 1887 mi.

  • Can I find deals for flights from Missoula to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missoula to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to South Carolina.

  • Can I find deals for business class flights from Missoula to South Carolina?

    Yes. Cheapflights offers flight deals from Missoula to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missoula to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Missoula to South Carolina (average of $308). Flying from Missoula to South Carolina in November is currently the most expensive (average of $678). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missoula to South Carolina

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Top 2 airlines flying from Missoula to South Carolina

Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$473FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$312Average$541FlexibilityNo cancel feeOn-time69%

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