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South Carolina

$231+ Cheap flights from Missoula (MSO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
ago. 23 — ago. 301
sáb. 8/23
sáb. 8/30
1 adult, Economy
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Cheap flight deals from Missoula to South Carolina

Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated agosto 18, 2025.

Round-trip from

$289
(Delta)

One-way from

$231
(Delta)
From Missoula Johnson-Bell Field to South Carolina
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One-way flight from Missoula Johnson-Bell Field to South Carolina
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Find flight deals from Missoula to South Carolina

Cheapest flights from Missoula to South Carolina
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/125:35 amMSO - CLT
1 stop9h 04mDelta
mar. 11/185:20 pmCLT - MSO
1 stop9h 12mDelta
Deal found 8/18$289
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/306:20 pmMSO - CLT
2 stops12h 32mDelta
sáb. 10/45:20 pmCLT - MSO
2 stops8h 26mDelta
Deal found 8/17$299
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:30 amMSO - CLT
1 stop8h 49mDelta
vie. 10/37:04 pmCLT - MSO
1 stop6h 42mDelta
Deal found 8/17$314
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:30 amMSO - CLT
1 stop8h 49mDelta
sáb. 10/45:20 pmCLT - MSO
2 stops8h 26mDelta
Deal found 8/17$319
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/265:45 amMSO - CLT
1 stop8h 35mDelta
sáb. 10/45:30 pmCLT - MSO
1 stop7h 43mDelta
Deal found 8/17$344
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/265:45 amMSO - CLT
1 stop8h 35mDelta
mar. 9/303:38 pmCLT - MSO
2 stops10h 40mDelta
Deal found 8/17$349
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:30 amMSO - CLT
1 stop8h 49mDelta
jue. 10/25:30 pmCLT - MSO
1 stop8h 48mDelta
Deal found 8/17$369
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:30 amMSO - CLT
1 stop8h 49mDelta
sáb. 10/45:30 pmCLT - MSO
1 stop7h 43mDelta
Deal found 8/17$374
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/175:45 amMSO - CLT
2 stops13h 50mDelta
mié. 9/2411:19 amCLT - MSO
2 stops14h 27mDelta
Deal found 8/16$378
This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/224:48 pmMSO - MYR
3 stops25h 18mMultiple Airlines
dom. 9/287:36 pmMYR - MSO
3 stops27h 44mMultiple Airlines
Deal found 8/16$492
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/221:51 pmMSO - MYR
1 stop7h 00mAmerican Airlines
dom. 9/285:15 amMYR - MSO
2 stops9h 45mAmerican Airlines
Deal found 8/16$579
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/56:25 amMSO - MYR
2 stops32h 31mUnited Airlines
sáb. 10/114:14 pmMYR - MSO
1 stop7h 12mUnited Airlines
Deal found 8/16$684

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.

Fly from

Missoula

Fly to

South Carolina

Route

Depart

Return

Price

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mié. 11/12

5:35 am-4:39 pm

1 stop9h 04m

Charlotte Douglas

mar. 11/18

5:20 pm-12:32 am

1 stop9h 12m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

vie. 1/16

2:27 pm-10:42 pm

1 stop6h 15m

Charlotte Douglas

lun. 1/19

8:15 am-1:27 pm

1 stop7h 12m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mié. 9/17

1:51 pm-12:28 am

1 stop8h 37m

Charlotte Douglas

mié. 9/24

5:50 pm-11:18 pm

1 stop7h 28m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mié. 11/12

5:35 am-4:39 pm

1 stop9h 04m

Charlotte Douglas

lun. 11/17

5:20 pm-12:32 am

1 stop9h 12m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mar. 9/30

6:20 pm-8:52 am

2 stops12h 32m

Charlotte Douglas

sáb. 10/4

5:30 pm-11:13 pm

1 stop7h 43m

$294

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

lun. 9/22

4:48 pm-8:06 pm

3 stops25h 18m

Myrtle Beach Intl

dom. 9/28

7:36 pm-9:20 pm

3 stops27h 44m

$492

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

lun. 9/22

1:51 pm-10:51 pm

1 stop7h 00m

Myrtle Beach Intl

dom. 9/28

5:15 am-1:00 pm

2 stops9h 45m

$579

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

dom. 10/5

6:25 am-4:56 pm

2 stops32h 31m

Myrtle Beach Intl

sáb. 10/11

4:14 pm-9:26 pm

1 stop7h 12m

$684

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

dom. 10/5

6:20 pm-9:51 am

2 stops13h 31m

Myrtle Beach Intl

sáb. 10/11

12:20 pm-9:40 pm

2 stops11h 20m

$709

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

lun. 9/22

4:17 pm-10:39 am

2 stops16h 22m

Myrtle Beach Intl

dom. 9/28

4:33 pm-9:57 am

2 stops19h 24m

$741

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Showing 1-10 of 14 results
1
2

Best time to book a flight from Missoula to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to South Carolina

What is the cheapest month to book a flight from Missoula to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Missoula to South Carolina (average of $217). Flying from Missoula to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSO to SC?

Find hourly flight availability from Missoula to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

When flying from Missoula to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated agosto 18, 2025.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,925 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Food

6.6

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,925 reviews
United Airlines
7.4
Good
8,925 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Food

6.6

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,925 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Food

6.6

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Missoula to South Carolina?

    Missoula Johnson-Bell Field (MSO), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Missoula to South Carolina.

  • How long is the flight from Missoula to South Carolina?

    Airlines like Delta, United Airlines, and American Airlines fly from Missoula to South Carolina in about 6h 15m. The time it takes to get you to your destination can typically vary by up to 2h 49m. Missoula and South Carolina are separated by a distance of 1887 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missoula to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missoula to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to South Carolina.

  • Can I find deals for business class flights from Missoula to South Carolina?

    Yes. Cheapflights offers flight deals from Missoula to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missoula to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Missoula to South Carolina (average of $217). Flying from Missoula to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missoula to South Carolina

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Top 2 airlines flying from Missoula to South Carolina

Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$410FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$348Average$588FlexibilityNo cancel feeOn-time69%

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