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$241+ Cheap flights from Missoula (MSO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheap flight deals from Missoula to South Carolina

Cheapest flights from Missoula to South Carolina
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:38 pmMSO - CLT
1 stop6h 00mUnited Airlines
Sat 1/36:00 amCLT - MSO
2 stops12h 20mUnited Airlines
Deal found 12/9$544
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amMSO - CLT
1 stop14h 38mUnited Airlines
Sat 1/36:00 amCLT - MSO
2 stops9h 36mUnited Airlines
Deal found 12/7$826
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amMSO - CLT
2 stops26h 03mUnited Airlines
Sun 12/286:00 amCLT - MSO
2 stops17h 41mUnited Airlines
Deal found 12/7$1,049
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:15 pmMSO - CLT
1 stop27h 23mUnited Airlines
Sun 12/286:00 amCLT - MSO
2 stops17h 41mUnited Airlines
Deal found 12/8$1,108

Find flight deals from Missoula to South Carolina

Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(Delta)

One-way from

$241
(Delta)
Provider with most accurate pricing for Missoula Johnson-Bell Field-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Missoula Johnson-Bell Field-Myrtle Beach Intl flights.
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From Missoula Johnson-Bell Field to South Carolina
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One-way flight from Missoula Johnson-Bell Field to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.

Fly from

Missoula

Fly to

South Carolina

Route

Depart

Return

Price

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Thu 1/22

5:00 am-4:00 pm

1 stop9h 00m

Charlotte Douglas

Sun 1/25

5:10 pm-12:28 am

1 stop9h 18m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 1/21

7:00 am-4:19 pm

1 stop7h 19m

Charlotte Douglas

Sat 1/24

7:50 am-12:50 pm

1 stop7h 00m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 1/21

5:00 am-4:00 pm

1 stop9h 00m

Charlotte Douglas

Tue 1/27

5:10 pm-12:28 am

1 stop9h 18m

$289

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 1/21

7:55 am-9:43 pm

2 stops11h 48m

Charlotte Douglas

Sat 1/24

5:10 pm-11:34 pm

1 stop8h 24m

$294

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Thu 1/22

6:00 am-9:16 pm

2 stops13h 16m

Charlotte Douglas

Sun 1/25

6:10 am-1:35 pm

2 stops9h 25m

$299

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 1/21

6:00 am-9:59 pm

2 stops13h 59m

Charlotte Douglas

Sat 1/24

11:15 am-9:51 pm

2 stops12h 36m

$299

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Sat 1/17

2:37 pm-10:59 pm

1 stop6h 22m

Charlotte Douglas

Wed 1/21

8:00 am-4:05 pm

1 stop10h 05m

$379

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Sat 1/24

2:37 pm-10:59 pm

1 stop6h 22m

Charlotte Douglas

Wed 1/28

4:19 pm-9:51 pm

1 stop7h 32m

$379

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Sat 1/24

2:46 pm-12:41 pm

2 stops19h 55m

Myrtle Beach Intl

Wed 1/28

1:25 pm-4:05 pm

2 stops28h 40m

$762

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 1/14

7:55 am-4:28 pm

1 stop6h 33m

$241

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 11 results
1
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Best time to book a flight from Missoula to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to South Carolina

What is the cheapest time of day to fly from MSO to SC?

Find hourly flight availability from Missoula to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 9, 2025.

When flying from Missoula to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 35% versus a flight in the morning.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 9, 2025.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,089 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,089 reviews
United Airlines
7.4
Good
9,089 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
American Airlines
7.2
Good
11,045 reviews
United Airlines
7.4
Good
9,089 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Missoula to South Carolina?

    Missoula Johnson-Bell Field (MSO), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Missoula to South Carolina.

  • How long is the flight from Missoula to South Carolina?

    Airlines like Delta, American Airlines, and United Airlines fly from Missoula to South Carolina in about 7h 19m. The time it takes to get you to your destination can typically vary by up to 12h 36m. Missoula and South Carolina are separated by a distance of 1887 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missoula to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missoula to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to South Carolina.

  • Can I find deals for business class flights from Missoula to South Carolina?

    Yes. Cheapflights offers flight deals from Missoula to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Missoula to South Carolina

Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$448FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$299Average$538FlexibilityNo cancel feeOn-time69%

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