$277+ Cheap flights from Missoula (MSO) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/21. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missoula to South Carolina
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Cheapest flights from Missoula to South CarolinaExplore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:08 pm
MSO
- CLT
1 stop6h 47m
American Airlines
Sun 5/107:06 am
CLT
- MSO
1 stop7h 32m
American Airlines
Deal found 3/9![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
MSO
- CLT
2 stops14h 43m
United Airlines
Sat 8/86:15 am
CLT
- MSO
1 stop7h 17m
United Airlines
Deal found 3/7![United Airlines logo]()
$390
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
MSO
- CLT
1 stop6h 21m
Delta
Tue 6/235:25 pm
CLT
- MSO
1 stop8h 59m
Delta
Deal found 3/5![Delta logo]()
$414
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:38 pm
MSO
- CLT
1 stop6h 21m
United Airlines
Tue 4/218:06 am
CLT
- MSO
1 stop7h 26m
United Airlines
Deal found 3/8![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
MSO
- CLT
1 stop6h 21m
Delta
Mon 6/225:25 pm
CLT
- MSO
1 stop8h 59m
Delta
Deal found 3/5![Delta logo]()
$445
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:38 pm
MSO
- CLT
1 stop6h 20m
United Airlines
Sun 4/194:17 pm
CLT
- MSO
1 stop7h 13m
United Airlines
Deal found 3/6![United Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
MSO
- MYR
1 stop8h 44m
Delta
Wed 6/245:35 pm
MYR
- MSO
1 stop8h 12m
Delta
Deal found 3/5![Delta logo]()
$449
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
MSO
- CLT
1 stop6h 21m
Delta
Tue 6/233:00 pm
CLT
- MSO
2 stops11h 24m
Delta
Deal found 3/5![Delta logo]()
$450
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:40 pm
MSO
- CLT
1 stop11h 27m
American Airlines
Sat 8/84:24 pm
CLT
- MSO
1 stop9h 04m
American Airlines
Deal found 3/7![American Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:32 am
MSO
- CLT
1 stop7h 37m
Delta
Sun 5/106:05 am
CLT
- MSO
2 stops10h 35m
Delta
Deal found 3/9![Delta logo]()
$474
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
MSO
- MYR
1 stop8h 44m
Delta
Tue 6/235:35 pm
MYR
- MSO
1 stop8h 12m
Delta
Deal found 3/5![Delta logo]()
$529
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:15 pm
MSO
- MYR
2 stops19h 02m
United Airlines
Wed 4/2211:00 am
MYR
- MSO
2 stops12h 30m
United Airlines
Deal found 3/8![United Airlines logo]()
$553
Best flights from Missoula to South CarolinaDiscover carefully curated flight deals from Missoula to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from Missoula to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
MSO
- CLT
1 stop6h 21m
Delta
Tue 6/235:25 pm
CLT
- MSO
1 stop8h 59m
Delta
Deal found 3/5![Delta logo]()
$414
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:38 pm
MSO
- CLT
1 stop6h 21m
United Airlines
Tue 4/218:06 am
CLT
- MSO
1 stop7h 26m
United Airlines
Deal found 3/7![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/132:08 pm
MSO
- MYR
1 stop8h 02m
American Airlines
Mon 6/224:38 pm
MYR
- MSO
1 stop8h 00m
American Airlines
Deal found 3/5![American Airlines logo]()
$681
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
MSO
- CLT
1 stop6h 21m
Delta
Tue 6/235:25 pm
CLT
- MSO
1 stop8h 59m
Delta
Deal found 3/5![Delta logo]()
$414
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
MSO
- CLT
1 stop6h 21m
Delta
Mon 6/225:25 pm
CLT
- MSO
1 stop8h 59m
Delta
Deal found 3/5![Delta logo]()
$445
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:15 pm
MSO
- MYR
2 stops19h 02m
United Airlines
Wed 4/2211:00 am
MYR
- MSO
2 stops12h 30m
United Airlines
Deal found 3/8![United Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:20 am
MSO
- CLT
1 stop8h 44m
Delta
Sun 5/106:05 am
CLT
- MSO
2 stops10h 35m
Delta
Deal found 3/6![Delta logo]()
$474
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:20 am
MSO
- CLT
1 stop8h 53m
Delta
Wed 4/155:15 pm
CLT
- MSO
1 stop9h 01m
Delta
Deal found 3/9![Delta logo]()
$480
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
MSO
- MYR
1 stop8h 44m
Delta
Mon 6/225:35 pm
MYR
- MSO
1 stop8h 12m
Delta
Deal found 3/5![Delta logo]()
$529
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/133:27 pm
MSO
- MYR
2 stops16h 42m
Delta
Mon 6/225:35 pm
MYR
- MSO
1 stop8h 12m
Delta
Deal found 3/5![Delta logo]()
$666
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:45 am
MSO
- MYR
1 stop8h 44m
Delta
Tue 6/235:35 pm
MYR
- MSO
1 stop8h 12m
Delta
Deal found 3/5![Delta logo]()
$670
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:45 am
MSO
- MYR
1 stop8h 44m
Delta
Mon 6/225:35 pm
MYR
- MSO
1 stop8h 12m
Delta
Deal found 3/5![Delta logo]()
$729
Last-minute flights from Missoula to South CarolinaDiscover last-minute flight deals from Missoula to South Carolina. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to South Carolina. Data last updated March 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:20 am
MSO
- CLT
1 stop8h 53m
Delta
Mon 3/165:24 pm
CLT
- MSO
1 stop9h 00m
Delta
Deal found 3/9![Delta logo]()
$504
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/282:35 pm
MSO
- CLT
1 stop6h 00m
United Airlines
Wed 4/16:45 am
CLT
- MSO
2 stops11h 21m
United Airlines
Deal found 3/5![United Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:04 pm
MSO
- CLT
2 stops12h 36m
Delta
Mon 4/135:15 pm
CLT
- MSO
1 stop9h 01m
Delta
Deal found 3/7![Delta logo]()
$474
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:20 am
MSO
- CLT
1 stop8h 53m
Delta
Wed 4/155:15 pm
CLT
- MSO
1 stop9h 01m
Delta
Deal found 3/9![Delta logo]()
$480
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:38 pm
MSO
- CLT
1 stop6h 20m
United Airlines
Sun 4/194:17 pm
CLT
- MSO
1 stop7h 13m
United Airlines
Deal found 3/6![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:38 pm
MSO
- CLT
1 stop6h 21m
United Airlines
Tue 4/218:06 am
CLT
- MSO
1 stop7h 26m
United Airlines
Deal found 3/8![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:15 pm
MSO
- MYR
2 stops19h 02m
United Airlines
Wed 4/2211:00 am
MYR
- MSO
2 stops12h 30m
United Airlines
Deal found 3/8![United Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:08 pm
MSO
- CLT
1 stop8h 43m
American Airlines
Sun 4/267:06 am
CLT
- MSO
1 stop7h 32m
American Airlines
Deal found 3/6![American Airlines logo]()
$489
One-way flights from Missoula to South CarolinaSearch for one-way flight options from Missoula to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from Missoula to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2110:25 am
MSO
- CLT
3 stops52h 20m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:45 am
MSO
- CLT
1 stop6h 21m
Delta
Deal found 3/9![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:45 am
MSO
- CLT
1 stop6h 21m
Delta
Deal found 3/7![Delta logo]()
$403
This Alaska Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:59 pm
MSO
- CLT
2 stops12h 46m
Alaska Airlines
Deal found 3/8![Alaska Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/212:08 pm
MSO
- CLT
1 stop8h 45m
American Airlines
Deal found 3/7![American Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/201:51 pm
MSO
- CLT
3 stops47h 03m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:15 am
MSO
- CLT
3 stops16h 30m
United Airlines
Deal found 3/7![United Airlines logo]()
$1,261
Find flight deals from Missoula to South Carolina
Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated March 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $369 (American Airlines) |
One-way from | $277 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaCharlotte
MSO - CLT
MSOCLT
Missoula Johnson-Bell Field
Fri 6/12
5:45 am-2:06 pm
1 stop6h 21m
Charlotte Douglas
Tue 6/23
5:25 pm-12:24 am
1 stop8h 59m
$414
MissoulaCharlotte
MSO - CLT
MSOCLT
Missoula Johnson-Bell Field
Thu 6/11
5:45 am-2:06 pm
1 stop6h 21m
Charlotte Douglas
Tue 6/23
5:25 pm-12:24 am
1 stop8h 59m
$414
Quickest round-trip
MissoulaCharlotte
MSO - CLT
MSOCLT
Missoula Johnson-Bell Field
Sat 4/18
2:38 pm-10:59 pm
1 stop6h 21m
Charlotte Douglas
Tue 4/21
8:06 am-1:32 pm
1 stop7h 26m
$419
MissoulaCharlotte
MSO - CLT
MSOCLT
Missoula Johnson-Bell Field
Thu 6/11
5:45 am-2:06 pm
1 stop6h 21m
Charlotte Douglas
Mon 6/22
5:25 pm-12:24 am
1 stop8h 59m
$445
MissoulaCharlotte
MSO - CLT
MSOCLT
Missoula Johnson-Bell Field
Wed 5/6
5:20 am-4:04 pm
1 stop8h 44m
Charlotte Douglas
Sun 5/10
6:05 am-2:40 pm
2 stops10h 35m
$474
MissoulaCharlotte
MSO - CLT
MSOCLT
Missoula Johnson-Bell Field
Wed 4/8
5:20 am-4:13 pm
1 stop8h 53m
Charlotte Douglas
Wed 4/15
5:15 pm-12:16 am
1 stop9h 01m
$480
MissoulaMyrtle Beach
MSO - MYR
MSOMYR
Missoula Johnson-Bell Field
Fri 6/12
5:45 am-4:29 pm
1 stop8h 44m
Myrtle Beach Intl
Mon 6/22
5:35 pm-11:47 pm
1 stop8h 12m
$529
MissoulaMyrtle Beach
MSO - MYR
MSOMYR
Missoula Johnson-Bell Field
Sat 4/18
5:15 pm-2:17 pm
2 stops19h 02m
Myrtle Beach Intl
Wed 4/22
11:00 am-9:30 pm
2 stops12h 30m
$553
MissoulaMyrtle Beach
MSO - MYR
MSOMYR
Missoula Johnson-Bell Field
Sat 6/13
3:27 pm-10:09 am
2 stops16h 42m
Myrtle Beach Intl
Mon 6/22
5:35 pm-11:47 pm
1 stop8h 12m
$666
MissoulaMyrtle Beach
MSO - MYR
MSOMYR
Missoula Johnson-Bell Field
Thu 6/11
5:45 am-4:29 pm
1 stop8h 44m
Myrtle Beach Intl
Tue 6/23
5:35 pm-11:47 pm
1 stop8h 12m
$670
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Missoula to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
MSO-CLT
MSO-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missoula to South Carolina
MSO-USSC
MSO-CLT
MSO-MYR
What is the cheapest time of day to fly from MSO to SC?
Find hourly flight availability from Missoula to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 11, 2026.
When flying from Missoula to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 66% versus a flight in the morning.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 11, 2026.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Crew
8.1
Comfort
7.3
Overall
7.4
Food
6.6
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Boarding
7.7
Crew
8.1
Comfort
7.3
Overall
7.4
Food
6.6
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Boarding
7.7
Crew
8.1
Comfort
7.3
Overall
7.4
Food
6.6
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missoula to South Carolina
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Missoula and South Carolina flights
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Missoula to South Carolina flights
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Top 2 airlines flying from Missoula to South Carolina
Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$534 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$597 | FlexibilityNo cancel fee | On-time69% |