HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$609+ Cheap flights from Lyon (LYS) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Lyon to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Lyon to South Carolina

Cheapest flights from Lyon to South Carolina
Explore the most affordable flight options available from Lyon to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:40 amLYS - CLT
2 stops18h 28mMultiple Airlines
Mon 11/175:45 amCLT - LYS
2 stops22h 20mMultiple Airlines
Deal found 10/29$621
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:55 pmLYS - CHS
2 stops24h 01mMultiple Airlines
Mon 11/179:02 amCHS - LYS
3 stops23h 08mMultiple Airlines
Deal found 10/29$639
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:25 amLYS - CLT
2 stops21h 14mUnited Airlines
Fri 12/196:00 amCLT - LYS
2 stops29h 40mUnited Airlines
Deal found 10/28$709
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:00 pmLYS - CLT
1 stop25h 05mBritish Airways
Sun 11/3010:55 pmCLT - LYS
1 stop13h 15mBritish Airways
Deal found 10/28$779
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:10 amLYS - CLT
2 stops20h 33mMultiple Airlines
Sun 11/3010:55 pmCLT - LYS
1 stop13h 15mMultiple Airlines
Deal found 10/28$791
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:10 amLYS - CLT
1 stop16h 20mAmerican Airlines
Mon 11/178:20 pmCLT - LYS
1 stop10h 55mAmerican Airlines
Deal found 10/29$803
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:55 amLYS - CLT
1 stop14h 00mLufthansa
Mon 11/176:50 pmCLT - LYS
2 stops17h 15mLufthansa
Deal found 10/29$807
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:10 amLYS - CHS
2 stops19h 02mAmerican Airlines
Mon 11/175:39 pmCHS - LYS
2 stops13h 36mAmerican Airlines
Deal found 10/29$867
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:10 amLYS - CLT
1 stop16h 10mAmerican Airlines
Sat 11/293:40 pmCLT - LYS
1 stop14h 15mAmerican Airlines
Deal found 10/28$880
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:20 amLYS - GSP
2 stops18h 50mUnited Airlines
Sat 11/225:28 pmGSP - LYS
2 stops42h 32mUnited Airlines
Deal found 10/30$897
This Air Canada deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:55 pmLYS - GSP
3 stops27h 24mMultiple Airlines
Sat 11/2210:00 amGSP - LYS
2 stops19h 05mMultiple Airlines
Deal found 10/30$1,253
This Air Canada deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:55 pmLYS - GSP
3 stops27h 24mAir Canada
Sat 11/229:10 amGSP - LYS
3 stops19h 55mAir Canada
Deal found 10/30$1,575

Cheap flight deals from Lyon to South Carolina

Keep the following information in mind while searching for Lyon to South Carolina flight deals. Data was last updated October 30, 2025.

Round-trip from

$621
(Mytrip)

One-way from

$609
(Mytrip)
From Lyon-Saint Exupéry to South Carolina
Search Deals
One-way flight from Lyon-Saint Exupéry to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Lyon to South Carolina that are best for you.

Fly from

Lyon

Fly to

South Carolina

Route

Depart

Return

Price

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 11/13

10:40 am-11:08 pm

2 stops18h 28m

Charlotte Douglas

Mon 11/17

5:45 am-10:05 am

2 stops22h 20m

$621

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Thu 11/13

1:55 pm-7:56 am

2 stops24h 01m

Charleston

Mon 11/17

9:02 am-2:10 pm

3 stops23h 08m

$639

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 2/14

8:55 am-4:55 pm

1 stop14h 00m

Charlotte Douglas

Sat 3/7

6:50 pm-5:40 pm

1 stop16h 50m

$693

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 3/7

9:45 pm-2:20 pm

1 stop22h 35m

Charlotte Douglas

Sat 3/21

11:50 pm-7:50 pm

1 stop15h 00m

$695

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 3/7

6:20 am-3:17 pm

2 stops38h 57m

Charlotte Douglas

Sat 3/21

5:05 pm-2:20 pm

2 stops40h 15m

$698

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 4/2

2:35 pm-11:29 pm

2 stops14h 54m

Charlotte Douglas

Mon 4/6

6:30 am-10:35 am

2 stops22h 05m

$706

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 12/12

6:25 am-9:39 pm

2 stops21h 14m

Charlotte Douglas

Fri 12/19

6:00 am-5:40 pm

2 stops29h 40m

$709

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Wed 4/1

6:45 am-9:49 am

2 stops33h 04m

Greenville

Sun 4/5

10:44 am-10:35 am

2 stops17h 51m

$797

LyonColumbia

LYS - CAE

LYSCAE

Lyon-Saint Exupéry

Wed 4/1

2:05 pm-11:20 am

2 stops27h 15m

Columbia Metropolitan

Sun 4/5

2:59 pm-1:45 pm

2 stops16h 46m

$830

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Wed 4/1

9:55 am-8:52 pm

2 stops16h 57m

Charleston

Sun 4/5

11:45 am-1:45 pm

2 stops20h 00m

$830

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 14 results
1
2

Best time to book a flight from Lyon to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lyon to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Lyon to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lyon to South Carolina?

    Lyon-Saint Exupéry (LYS) is the airport you will fly out of if you book a flight from Lyon to South Carolina. It is only a 12.5 mi journey to Lyon-Saint Exupéry (LYS) from Lyon’s city center.

  • How long is the flight from Lyon to South Carolina?

    For as low as $693, Lufthansa can have you in South Carolina from Lyon in 14h. Airlines will cover a distance of 4357 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Lyon to South Carolina?

    The most popular flight routes from Lyon to South Carolina are Lyon-Saint Exupéry - Charlotte Douglas, Lyon-Saint Exupéry - Columbia Metropolitan and Lyon-Saint Exupéry - Greenville.

  • Can I find deals for flights from Lyon to South Carolina that include hotel bookings?

    Yes. In addition to deals on Lyon to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to South Carolina.

  • Can I find deals for business class flights from Lyon to South Carolina?

    Yes. Cheapflights offers flight deals from Lyon to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Lyon to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Lyon to Newark flights
Lyon to John F Kennedy Intl flights
Lyon to LaGuardia flights
Lyon to Miami flights
Lyon to Fort Lauderdale flights
Lyon to Los Angeles flights
Lyon to Las Vegas flights
Clermont-Ferrand to John F Kennedy Intl flights
Lyon to West Palm Beach flights
Clermont-Ferrand to Newark flights
Lyon to San Francisco flights
Lyon to Dallas/Fort Worth flights
Lyon to Boston flights
Lyon to Orlando flights
Lyon to O'Hare Intl flights
Lyon to New Orleans flights
Lyon to Atlanta flights
Lyon to Dulles Intl flights
Lyon to Baltimore flights
Lyon to Honolulu flights
Lyon to Seattle flights
Lyon to Charlotte flights
Lyon to Philadelphia flights
Lyon to San Diego flights
Lyon to Denver flights
Lyon to Minneapolis flights
Lyon to Hobby flights
Lyon to George Bush Intcntl flights
Lyon to Kansas City flights
Lyon to Detroit flights
Lyon to Tampa flights
Lyon to Portland flights
Lyon to Raleigh flights
Lyon to Austin flights
Lyon to Oakland flights
Lyon to Sky Harbor Intl flights
Lyon to Jacksonville flights
Lyon to Cincinnati flights
Clermont-Ferrand to Fort Lauderdale flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.