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South Carolina

$387+ Cheap flights from Lyon (LYS) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — CHS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Lyon to South Carolina

Keep the following information in mind while searching for Lyon to South Carolina flight deals. Data was last updated July 31, 2025.

Round-trip from

$622
(American Airlines)

One-way from

$387
(Kiwi.com)
From Lyon-Saint Exupéry to South Carolina
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One-way flight from Lyon-Saint Exupéry to South Carolina
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Find flight deals from Lyon to South Carolina

Cheapest flights from Lyon to South Carolina
Explore the most affordable flight options available from Lyon to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:35 amLYS - CLT
1 stop12h 30mAmerican Airlines
Thu 11/278:15 pmCLT - LYS
1 stop18h 05mAmerican Airlines
Deal found 7/30$622
This British Airways deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:00 pmLYS - CLT
1 stop27h 05mBritish Airways
Thu 11/271:02 pmCLT - LYS
2 stops17h 23mBritish Airways
Deal found 7/30$625
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2510:20 amLYS - CLT
2 stops15h 00mDelta
Tue 11/116:59 pmCLT - LYS
2 stops16h 36mDelta
Deal found 7/30$671
This Gotogate deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:50 amLYS - CLT
2 stops39h 27mAir Canada
Wed 11/126:00 amCLT - LYS
2 stops23h 05mAir Canada
Deal found 7/29$672
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:15 amLYS - CLT
2 stops23h 43mUnited Airlines
Thu 11/2710:00 amCLT - LYS
3 stops18h 10mUnited Airlines
Deal found 7/30$688
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:40 amLYS - CHS
2 stops18h 25mAmerican Airlines
Mon 10/204:41 pmCHS - LYS
2 stops17h 49mAmerican Airlines
Deal found 7/29$720
This Lufthansa deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:50 pmLYS - CLT
1 stop28h 55mLufthansa
Sun 11/26:50 pmCLT - LYS
1 stop16h 55mLufthansa
Deal found 7/30$768
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 amLYS - CHS
3 stops32h 55mMultiple Airlines
Mon 10/206:08 pmCHS - LYS
3 stops38h 22mMultiple Airlines
Deal found 7/29$770
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/186:10 amLYS - GSP
2 stops19h 06mAmerican Airlines
Thu 9/45:20 pmGSP - LYS
2 stops21h 35mAmerican Airlines
Deal found 7/29$834
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/186:50 amLYS - GSP
2 stops20h 10mUnited Airlines
Thu 9/48:00 amGSP - LYS
2 stops20h 35mUnited Airlines
Deal found 7/31$920
This Flighttix deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/128:20 pmLYS - CHS
2 stops31h 04mScandinavian Airlines
Mon 8/255:35 pmCHS - LYS
2 stops20h 05mScandinavian Airlines
Deal found 7/30$1,140
This Expedia deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/149:25 amLYS - CLT
1 stop13h 20mMultiple Airlines
Mon 8/183:15 pmCLT - LYS
2 stops15h 10mMultiple Airlines
Deal found 7/30$1,169

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Lyon to South Carolina that are best for you.

Fly from

Lyon

Fly to

South Carolina

Route

Depart

Return

Price

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 11/6

9:35 am-4:05 pm

1 stop12h 30m

Charlotte Douglas

Thu 11/27

8:15 pm-8:20 pm

1 stop18h 05m

$622

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 11/6

7:00 pm-4:05 pm

1 stop27h 05m

Charlotte Douglas

Thu 11/27

1:02 pm-12:25 pm

2 stops17h 23m

$625

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 10/25

10:20 am-7:20 pm

2 stops15h 00m

Charlotte Douglas

Tue 11/11

6:59 pm-5:35 pm

2 stops16h 36m

$671

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 10/25

6:50 am-4:17 pm

2 stops39h 27m

Charlotte Douglas

Wed 11/12

6:00 am-11:05 am

2 stops23h 05m

$672

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 11/6

6:15 am-11:58 pm

2 stops23h 43m

Charlotte Douglas

Thu 11/27

10:00 am-10:10 am

3 stops18h 10m

$688

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Thu 10/2

11:40 am-12:05 am

2 stops18h 25m

Charleston

Mon 10/20

4:41 pm-4:30 pm

2 stops17h 49m

$720

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Mon 10/20

5:50 pm-4:45 pm

1 stop28h 55m

Charlotte Douglas

Sun 11/2

6:50 pm-5:45 pm

1 stop16h 55m

$768

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Thu 10/2

5:20 am-8:15 am

3 stops32h 55m

Charleston

Mon 10/20

6:08 pm-2:30 pm

3 stops38h 22m

$770

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Mon 8/18

6:10 am-7:16 pm

2 stops19h 06m

Greenville

Thu 9/4

5:20 pm-8:55 pm

2 stops21h 35m

$834

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Mon 8/18

6:50 am-9:00 pm

2 stops20h 10m

Greenville

Thu 9/4

8:00 am-10:35 am

2 stops20h 35m

$920

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 22 results
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Best time to book a flight from Lyon to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lyon to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Lyon to South Carolina, such as Delta, United Airlines, and Scandinavian Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Scandinavian Airlines
7.4
Good
1,457 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Brussels Airlines
7.3
Good
350 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Lyon to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lyon to South Carolina?

    Lyon-Saint Exupéry (LYS) is the airport you will fly out of if you book a flight from Lyon to South Carolina. It is only a 12.5 mi journey to Lyon-Saint Exupéry (LYS) from Lyon’s city center.

  • What are the cheapest airlines to fly from Lyon to South Carolina one-way?

    The cheapest airlines for a one-way flight from Lyon to South Carolina are Aer Lingus ($643), Lufthansa ($756), and American Airlines ($818).

  • What are the most popular routes from Lyon to South Carolina?

    The most popular flight routes from Lyon to South Carolina are Lyon-Saint Exupéry - Charlotte Douglas, Lyon-Saint Exupéry - Greenville and Lyon-Saint Exupéry - Columbia Metropolitan.

  • Can I find deals for flights from Lyon to South Carolina that include hotel bookings?

    Yes. In addition to deals on Lyon to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to South Carolina.

  • Can I find deals for business class flights from Lyon to South Carolina?

    Yes. Cheapflights offers flight deals from Lyon to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lyon to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Lyon to South Carolina (average of $217). Flying from Lyon to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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