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South Carolina

$538+ Cheap flights from Lyon (LYS) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — CHS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Lyon to South Carolina

Cheapest flights from Lyon to South Carolina
Explore the most affordable flight options available from Lyon to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:00 amLYS - CHS
2 stops18h 48mUnited Airlines
Thu 1/12:50 pmCHS - LYS
2 stops14h 20mUnited Airlines
Deal found 12/15$1,405
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:00 amLYS - CLT
3 stops30h 03mMultiple Airlines
Wed 12/249:30 amCLT - LYS
2 stops26h 30mMultiple Airlines
Deal found 12/16$1,490
This Mytrip deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:25 amLYS - CHS
3 stops43h 58mMultiple Airlines
Thu 1/12:15 pmCHS - LYS
3 stops26h 15mMultiple Airlines
Deal found 12/15$1,733
This Expedia deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:10 amLYS - CHS
2 stops35h 21mMultiple Airlines
Thu 12/252:50 pmCHS - LYS
2 stops21h 30mMultiple Airlines
Deal found 12/17$1,813
This Gotogate deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:25 amLYS - CLT
2 stops39h 52mAir Canada
Wed 12/249:30 amCLT - LYS
2 stops19h 35mAir Canada
Deal found 12/16$1,820

Find flight deals from Lyon to South Carolina

Keep the following information in mind while searching for Lyon to South Carolina flight deals. Data was last updated December 18, 2025.

Round-trip from

$741
(United Airlines)

One-way from

$538
(Expedia)
From Lyon-Saint Exupéry to South Carolina
Search Deals
One-way flight from Lyon-Saint Exupéry to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Lyon to South Carolina that are best for you.

Fly from

Lyon

Fly to

South Carolina

Route

Depart

Return

Price

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 1/31

10:50 am-8:57 pm

2 stops16h 07m

Charlotte Douglas

Sat 2/14

6:50 pm-12:25 pm

1 stop11h 35m

$727

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Sat 1/31

8:55 am-4:55 pm

1 stop14h 00m

Charlotte Douglas

Sat 2/14

6:50 pm-12:25 pm

1 stop11h 35m

$731

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 1/29

10:40 am-2:13 pm

2 stops33h 33m

Charlotte Douglas

Mon 2/2

7:01 am-11:05 am

2 stops22h 04m

$741

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 1/29

12:25 pm-8:40 am

2 stops26h 15m

Charlotte Douglas

Mon 2/2

8:25 pm-1:15 pm

1 stop10h 50m

$743

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 5/14

6:35 am-2:57 pm

2 stops38h 22m

Charlotte Douglas

Sun 5/24

3:35 pm-11:40 am

2 stops38h 05m

$780

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Wed 4/15

6:45 am-6:58 pm

2 stops18h 13m

Charlotte Douglas

Sat 5/2

11:05 am-11:40 am

2 stops18h 35m

$799

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Thu 5/14

6:35 am-11:29 pm

2 stops22h 54m

Charlotte Douglas

Sun 5/24

6:40 pm-12:20 pm

1 stop11h 40m

$800

LyonColumbia

LYS - CAE

LYSCAE

Lyon-Saint Exupéry

Thu 2/19

6:10 am-7:46 pm

2 stops19h 36m

Columbia Metropolitan

Mon 2/23

7:00 am-1:15 pm

2 stops24h 15m

$813

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Thu 2/19

6:10 am-8:44 pm

2 stops20h 34m

Greenville

Mon 2/23

3:56 pm-5:30 pm

2 stops19h 34m

$814

LyonCharleston

LYS - CHS

LYSCHS

Lyon-Saint Exupéry

Thu 2/19

6:10 am-7:14 pm

2 stops19h 04m

Charleston

Mon 2/23

4:30 pm-5:30 pm

2 stops19h 00m

$814

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 19 results
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Best time to book a flight from Lyon to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lyon to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Lyon to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lyon to South Carolina?

    Lyon-Saint Exupéry (LYS) is the airport you will fly out of if you book a flight from Lyon to South Carolina. It is only a 12.5 mi journey to Lyon-Saint Exupéry (LYS) from Lyon’s city center.

  • How long is the flight from Lyon to South Carolina?

    For as low as $731, Lufthansa can have you in South Carolina from Lyon in 14h. Airlines will cover a distance of 4357 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Lyon to South Carolina?

    The most popular flight routes from Lyon to South Carolina are Lyon-Saint Exupéry - Charlotte Douglas, Lyon-Saint Exupéry - Charleston and Lyon-Saint Exupéry - Greenville.

  • Can I find deals for flights from Lyon to South Carolina that include hotel bookings?

    Yes. In addition to deals on Lyon to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to South Carolina.

  • Can I find deals for business class flights from Lyon to South Carolina?

    Yes. Cheapflights offers flight deals from Lyon to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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