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South Carolina

$640+ Cheap flights from Lyon (LYS) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Lyon to South Carolina

Keep the following information in mind while searching for Lyon to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$645
(Flighttix)
From Lyon-Saint Exupéry to South Carolina
Search Deals

Find flight deals from Lyon to South Carolina

Cheapest flights from Lyon to South Carolina
Explore the most affordable flight options available from Lyon to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2211:10 amLYS - CLT
1 stop33h 50mAmerican Airlines
Mon 9/297:55 pmCLT - LYS
1 stop14h 35mAmerican Airlines
Deal found 9/14$640
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:25 amLYS - CLT
3 stops21h 36mMultiple Airlines
Wed 11/51:39 pmCLT - LYS
2 stops15h 26mMultiple Airlines
Deal found 9/14$647
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:40 pmLYS - CLT
1 stop30h 15mBritish Airways
Sat 11/1510:40 pmCLT - LYS
2 stops32h 20mBritish Airways
Deal found 9/15$657
This British Airways deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:00 pmLYS - CLT
1 stop26h 50mBritish Airways
Wed 11/56:33 pmCLT - LYS
2 stops13h 37mBritish Airways
Deal found 9/14$673
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:10 pmLYS - CLT
1 stop22h 50mBritish Airways
Sun 11/210:55 pmCLT - LYS
1 stop32h 20mBritish Airways
Deal found 9/15$678
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:25 amLYS - CLT
2 stops17h 26mUnited Airlines
Sun 11/27:44 pmCLT - LYS
2 stops33h 26mUnited Airlines
Deal found 9/15$724
This Flighttix deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1010:50 amLYS - CLT
2 stops41h 52mScandinavian Airlines
Sat 11/157:30 amCLT - LYS
2 stops29h 55mScandinavian Airlines
Deal found 9/15$740
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/201:00 pmLYS - CLT
1 stop33h 45mUnited Airlines
Sun 11/27:44 pmCLT - LYS
2 stops33h 26mUnited Airlines
Deal found 9/15$802
This Air France deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/202:05 pmLYS - CLT
2 stops15h 45mAir France
Sun 11/25:25 pmCLT - LYS
2 stops14h 40mAir France
Deal found 9/13$804
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:40 amLYS - GSP
2 stops21h 01mDelta
Thu 1/110:03 amGSP - LYS
2 stops17h 27mDelta
Deal found 9/14$1,083
This Air Canada deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:55 pmLYS - GSP
3 stops27h 01mMultiple Airlines
Thu 1/16:23 amGSP - LYS
2 stops46h 42mMultiple Airlines
Deal found 9/14$2,547

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Lyon to South Carolina that are best for you.

Fly from

Lyon

Fly to

South Carolina

Route

Depart

Return

Price

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Wed 10/29

7:00 pm-4:50 pm

1 stop26h 50m

Charlotte Douglas

Wed 11/5

6:25 pm-6:05 pm

1 stop17h 40m

$673

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Fri 10/31

6:25 am-6:51 pm

2 stops17h 26m

Charlotte Douglas

Sun 11/2

7:44 pm-11:10 am

2 stops33h 26m

$724

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Tue 11/11

8:10 pm-10:42 pm

2 stops32h 32m

Charlotte Douglas

Sat 11/15

2:12 pm-7:25 pm

2 stops23h 13m

$740

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Mon 11/10

10:50 am-10:42 pm

2 stops41h 52m

Charlotte Douglas

Sat 11/15

7:30 am-7:25 pm

2 stops29h 55m

$740

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Mon 10/20

1:00 pm-4:45 pm

1 stop33h 45m

Charlotte Douglas

Sun 11/2

7:44 pm-11:10 am

2 stops33h 26m

$802

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Mon 10/20

2:05 pm-11:50 pm

2 stops15h 45m

Charlotte Douglas

Sun 11/2

5:25 pm-2:05 pm

2 stops14h 40m

$804

LyonCharlotte

LYS - CLT

LYSCLT

Lyon-Saint Exupéry

Mon 10/20

5:50 pm-4:45 pm

1 stop28h 55m

Charlotte Douglas

Sun 11/2

6:50 pm-8:15 am

1 stop31h 25m

$832

LyonColumbia

LYS - CAE

LYSCAE

Lyon-Saint Exupéry

Mon 1/5

10:40 am-2:00 pm

2 stops57h 20m

Columbia Metropolitan

Fri 1/23

8:00 am-2:15 pm

2 stops24h 15m

$1,012

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Thu 12/18

6:40 am-9:41 pm

2 stops21h 01m

Greenville

Thu 1/1

10:03 am-9:30 am

2 stops17h 27m

$1,083

LyonGreenville

LYS - GSP

LYSGSP

Lyon-Saint Exupéry

Thu 12/18

1:55 pm-10:56 am

3 stops27h 01m

Greenville

Thu 1/1

6:23 am-11:05 am

2 stops46h 42m

$2,547

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 11 results
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Best time to book a flight from Lyon to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lyon to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Lyon to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lyon to South Carolina?

    Lyon-Saint Exupéry (LYS) is the airport you will fly out of if you book a flight from Lyon to South Carolina. It is only a 12.5 mi journey to Lyon-Saint Exupéry (LYS) from Lyon’s city center.

  • How long is the flight from Lyon to South Carolina?

    For as low as $724, British Airways can have you in South Carolina from Lyon in 17h 26m. Airlines will cover a distance of 4357 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Lyon to South Carolina?

    The most popular flight routes from Lyon to South Carolina are Lyon-Saint Exupéry - Charlotte Douglas, Lyon-Saint Exupéry - Charleston and Lyon-Saint Exupéry - Columbia Metropolitan.

  • Can I find deals for flights from Lyon to South Carolina that include hotel bookings?

    Yes. In addition to deals on Lyon to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to South Carolina.

  • Can I find deals for business class flights from Lyon to South Carolina?

    Yes. Cheapflights offers flight deals from Lyon to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lyon to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Lyon to South Carolina (average of $217). Flying from Lyon to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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