$309+ Cheap flights from Harrisburg to Sioux Falls (MDT - FSD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — FSD
Oct 9 — Oct 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Harrisburg to Sioux Falls with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Sioux Falls
Cheapest
Best
Last-minute
One-way
Cheapest flights from Harrisburg to Sioux FallsExplore the most affordable flight options available from Harrisburg to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Harrisburg to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:29 am -
1 stop6h 47m
Wed 10/72:48 pm -
1 stop6h 31m
Deal found 9/5![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:54 pm -
1 stop6h 17m
Wed 10/147:50 am -
1 stop4h 37m
Deal found 9/7![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:30 am -
1 stop6h 43m
Mon 10/1912:53 pm -
1 stop9h 06m
Deal found 9/9![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:52 pm -
1 stop5h 37m
Mon 11/93:29 pm -
1 stop5h 46m
Deal found 9/5![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:39 am -
2 stops10h 27m
Tue 12/13:30 pm -
1 stop5h 47m
Deal found 9/8![American Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:54 pm -
1 stop6h 35m
Mon 10/512:53 pm -
2 stops9h 06m
Deal found 9/8![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:30 am -
1 stop6h 43m
Wed 10/1412:07 pm -
2 stops9h 35m
Deal found 9/7![American Airlines logo]()
$433
Best flights from Harrisburg to Sioux FallsDiscover carefully curated flight deals from Harrisburg to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Harrisburg to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:35 pm -
2 stops10h 54m
Wed 10/72:48 pm -
1 stop6h 31m
Deal found 9/7![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:54 pm -
1 stop6h 17m
Wed 10/147:50 am -
1 stop4h 37m
Deal found 9/7![United Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am -
2 stops9h 31m
Sat 1/93:06 pm -
1 stop4h 49m
Deal found 9/8![United Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:35 pm -
2 stops11h 06m
Sun 10/2512:53 pm -
1 stop9h 06m
Deal found 9/9![American Airlines logo]()
$468
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:30 am -
1 stop5h 10m
Wed 1/2710:00 am -
1 stop5h 58m
Deal found 9/4![United Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:36 am -
2 stops10h 12m
Mon 11/93:29 pm -
1 stop5h 46m
Deal found 9/6![American Airlines logo]()
$478
Last-minute flights from Harrisburg to Sioux FallsDiscover last-minute flight deals from Harrisburg to Sioux Falls. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Sioux Falls. Data last updated September 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:29 am -
1 stop6h 47m
Wed 10/72:48 pm -
1 stop6h 31m
Deal found 9/5![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:54 pm -
1 stop6h 35m
Mon 10/512:53 pm -
2 stops9h 06m
Deal found 9/8![American Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:54 pm -
1 stop6h 17m
Wed 10/147:50 am -
1 stop4h 37m
Deal found 9/7![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:30 am -
1 stop6h 43m
Wed 10/1412:07 pm -
2 stops9h 35m
Deal found 9/7![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:09 pm -
1 stop5h 39m
Mon 10/1912:53 pm -
1 stop9h 06m
Deal found 9/9![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:30 am -
1 stop6h 43m
Mon 10/1912:53 pm -
1 stop9h 06m
Deal found 9/9![American Airlines logo]()
$397
One-way flights from Harrisburg to Sioux FallsSearch for one-way flight options from Harrisburg to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Harrisburg to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:29 am -
1 stop6h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:53 pm -
2 stops23h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:29 am -
1 stop6h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$387
Find flight deals from Harrisburg to Sioux Falls
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $325 (American Airlines) |
One-way from | $309 (American Airlines) |
Popular in | June |
Cheapest in | September |
Average price | $326 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Harrisburg to Sioux Falls that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Sun 10/4
6:29 am-12:16 pm
1 stop6h 47m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$309
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Wed 9/30
2:35 pm-12:29 am
2 stops10h 54m
Sioux Falls Joe Foss Field
Wed 10/7
2:48 pm-10:19 pm
1 stop6h 31m
$330
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Wed 10/7
5:54 pm-11:11 pm
1 stop6h 17m
Sioux Falls Joe Foss Field
Wed 10/14
7:50 am-1:27 pm
1 stop4h 37m
$371
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Wed 9/16
6:29 am-12:16 pm
1 stop6h 47m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$387
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Wed 1/6
6:00 am-2:31 pm
2 stops9h 31m
Sioux Falls Joe Foss Field
Sat 1/9
3:06 pm-8:55 pm
1 stop4h 49m
$416
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Sun 10/4
8:53 pm-12:48 pm
3 stops40h 55m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$417
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Tue 10/20
2:35 pm-12:41 am
2 stops11h 06m
Sioux Falls Joe Foss Field
Sun 10/25
12:53 pm-10:59 pm
1 stop9h 06m
$468
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Sat 1/23
6:30 am-10:40 am
1 stop5h 10m
Sioux Falls Joe Foss Field
Wed 1/27
10:00 am-4:58 pm
1 stop5h 58m
$475
HarrisburgSioux Falls
MDT Harrisburg - FSD Sioux Falls Joe Foss Field
MDTFSD
Harrisburg
Fri 11/6
9:36 am-6:48 pm
2 stops10h 12m
Sioux Falls Joe Foss Field
Mon 11/9
3:29 pm-10:15 pm
1 stop5h 46m
$478
Sorted by cheapest first
Compare providers for flights from Harrisburg to Sioux Falls
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Sioux Falls in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Sioux Falls flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-Sioux Falls flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to Sioux Falls
Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Harrisburg with our price prediction graph.
MDT-FSD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to Sioux Falls
What is the cheapest month to book a flight from Harrisburg to Sioux Falls?
Currently, September is the cheapest month in which you can book a flight from Harrisburg to Sioux Falls (average of $326). Flying from Harrisburg to Sioux Falls in June is currently the most expensive (average of $978). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to Sioux Falls?
Airfare is below average for this route at the moment.
Harrisburg to Sioux Falls flights typically cost between $326 and $350 in September.The cheapest round-trip price found within the last 5 days was $325 on American Airlines (Sep 30-Oct 7).
Reviews of airlines servicing Sioux Falls
Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated September 9, 2026.
See what other customers who have flown with United Airlines and American Airlines from Harrisburg to Sioux Falls have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.6
Entertainment
7.1
Overall
7.4
Comfort
7.3
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.6
Entertainment
7.1
Overall
7.4
Comfort
7.3
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Food
6.6
Entertainment
7.1
Overall
7.4
Comfort
7.3
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Sioux Falls?
Book flights to Sioux Falls if you plan to visit one of these locationsYankton
Marshall
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Sioux Falls flight routes
Alternative routes for Harrisburg to Sioux Falls
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Sioux Falls by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Harrisburg to Sioux Falls by cabin class
Find flights from Harrisburg to Sioux Falls, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and Sioux Falls flights
Browse other Harrisburg and Sioux Falls flight options. Last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Sioux Falls
Explore flights to Sioux Falls departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Top 2 airlines flying from Harrisburg to Sioux Falls
Discover the top 2 airlines that operate flights from Harrisburg to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$450 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$359 | Average$414 | FlexibilityNo cancel fee | On-time69% |