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Santo Domingo

$243+ Cheap flights from Santiago (SCL) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SDQ
Nov 1 — Nov 81
Sat 11/1
Sat 11/8
1 adult, Economy
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Cheap flight deals from Santiago to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$474
(Priceline)

One-way from

$243
(Priceline)

Popular in

January

Cheapest in

November

Average price

$535

Good one-way deal

$261 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Santo Domingo Las Americas flights.
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From Santiago Arturo Merino Benitez to Santo Domingo Las Americas
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One-way flight from Santiago Arturo Merino Benitez to Santo Domingo Las Americas
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Highest demand for flights based on searches. 11% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Santo Domingo Las Americas.
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Find flight deals from Santiago to Santo Domingo

Cheapest flights from Santiago to Santo Domingo
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2025.

This Avianca deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:10 amSCL - SDQ
1 stop11h 05mAvianca
Thu 10/1611:45 amSDQ - SCL
1 stop16h 30mAvianca
Deal found 9/30$473
This Priceline deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:35 amSCL - SDQ
1 stop16h 15mAvianca
Fri 11/215:45 pmSDQ - SCL
1 stop10h 45mAvianca
Deal found 9/29$474
This Copa Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:35 amSCL - SDQ
1 stop19h 50mCopa Airlines
Mon 10/278:58 amSDQ - SCL
1 stop10h 22mCopa Airlines
Deal found 10/1$475
This Copa Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/263:35 amSCL - SDQ
1 stop19h 50mCopa Airlines
Tue 11/186:00 amSDQ - SCL
1 stop20h 43mCopa Airlines
Deal found 10/2$476
This Copa Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2012:20 pmSCL - SDQ
1 stop11h 05mCopa Airlines
Fri 11/2811:55 amSDQ - SCL
1 stop11h 11mCopa Airlines
Deal found 10/1$478
This Copa Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/301:08 amSCL - SDQ
1 stop11h 32mCopa Airlines
Fri 12/58:55 amSDQ - SCL
1 stop10h 26mCopa Airlines
Deal found 10/1$498
This Copa Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/283:23 amSCL - SDQ
1 stop13h 52mCopa Airlines
Sat 1/38:50 amSDQ - SCL
1 stop14h 42mCopa Airlines
Deal found 10/2$508
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/204:47 amSCL - SDQ
1 stop12h 28mCopa Airlines
Mon 10/2712:00 pmSDQ - SCL
1 stop11h 05mCopa Airlines
Deal found 9/29$510
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2112:29 pmSCL - SDQ
1 stop10h 56mCopa Airlines
Mon 10/2712:00 pmSDQ - SCL
1 stop11h 05mCopa Airlines
Deal found 9/29$512
This Copa Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:12 amSCL - SDQ
1 stop12h 03mCopa Airlines
Thu 12/186:00 amSDQ - SCL
1 stop17h 24mCopa Airlines
Deal found 10/2$528
This Copa Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/13:35 amSCL - SDQ
1 stop10h 32mCopa Airlines
Mon 10/611:57 amSDQ - SCL
1 stop14h 45mCopa Airlines
Deal found 9/30$536

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Santiago

Fly to

Santo Domingo

Route

Depart

Return

Price

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sun 10/19

3:35 am-10:25 pm

1 stop19h 50m

Santo Domingo Las Americas

Wed 10/29

12:00 pm-11:40 pm

1 stop10h 40m

$475

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 10/22

3:35 am-10:25 pm

1 stop19h 50m

Santo Domingo Las Americas

Mon 10/27

8:58 am-8:20 pm

1 stop10h 22m

$475

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sun 10/26

3:35 am-10:25 pm

1 stop19h 50m

Santo Domingo Las Americas

Sun 11/2

11:55 am-3:43 am

1 stop14h 48m

$476

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 10/29

5:11 am-4:15 pm

1 stop12h 04m

Santo Domingo Las Americas

Wed 11/5

11:55 am-11:41 pm

1 stop10h 46m

$476

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 10/28

12:20 pm-10:25 pm

1 stop11h 05m

Santo Domingo Las Americas

Sun 11/2

11:55 am-12:06 am

1 stop11h 11m

$476

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Fri 10/31

3:23 am-10:25 pm

1 stop20h 02m

Santo Domingo Las Americas

Sun 11/30

6:00 am-11:41 pm

1 stop16h 41m

$478

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sun 11/2

3:23 am-10:25 pm

1 stop20h 02m

Santo Domingo Las Americas

Sun 11/9

8:55 am-12:06 am

1 stop14h 11m

$478

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 10/15

7:10 am-5:15 pm

1 stop11h 05m

$243

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Fri 11/28

6:00 am-4:45 pm

1 stop11h 45m

$245

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Fri 12/5

6:00 am-4:45 pm

1 stop11h 45m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/1

Showing 1-10 of 14 results
1
2

Compare providers for flights from Santiago to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Santo Domingo in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santo Domingo

How far ahead should I book a flight from Santiago to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santo Domingo. Price data was last updated on September 26, 2025.

Booking 12 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $362). Flying from Santiago to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 2, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santiago to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,542 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Food

6.8

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,542 reviews
Copa Airlines
7.6
Good
1,542 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Food

6.8

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,443 reviews
Copa Airlines
7.6
Good
1,542 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Food

6.8

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Santo Domingo?

    Departing from Santiago to Santo Domingo will take you 19h 50m. There are 3579 mi between Santiago and Santo Domingo.

  • What are the cheapest airlines flying from Santiago to Santo Domingo round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $495. Another option worth looking into is Avianca, starting at $502 round trip. Copa Airlines is 12% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Santo Domingo?

    The cheapest flight price from Santiago to Santo Domingo is $261. On average you can expect to pay $261. The most popular route, (Santiago Arturo Merino Benitez - Santo Domingo Las Americas), can usually be booked for $498.

  • Can I find deals for flights from Santiago to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Santiago to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santo Domingo.

  • Can I find deals for business class flights from Santiago to Santo Domingo?

    Yes. Cheapflights offers flight deals from Santiago to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $362). Flying from Santiago to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Punta Cana flights

Top 2 airlines flying from Santiago to Santo Domingo

Discover the top 2 airlines that operate flights from Santiago to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$495Average$591FlexibilityNo cancel feeOn-time70%
AviancaCheapest$502Average$533FlexibilityNo cancel feeOn-time71%

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