What are the cheapest airlines flying from Madrid to Santiago de los Caballeros round-trip?

Flying on JetBlue is currently your cheapest option to Santiago de los Caballeros, with prices starting at $726. Additional round-trip tickets that might be worth considering are offered by Delta and Air Europa, with the lowest prices starting at $802 and $1,223, respectively. JetBlue is 21% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Madrid to Santiago de los Caballeros one-way?

To fly one-way, consider booking your trip with Air Europa, which is currently one of the cheapest options available, starting at $777. United Airlines flights start at $1,018 while deals on JetBlue start at $1,026 one-way.

What is the cheapest day to fly from Madrid to Santiago de los Caballeros?

Travelers seeking maximum savings on their Madrid to Santiago de los Caballeros flight should consider departing on Thursday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Madrid to Santiago de los Caballeros?

Users have found that flying from Madrid to Santiago de los Caballeros on a Friday typically leans towards higher prices. However, this doesn’t mean you still can’t find a deal. Flexibility with other aspects of your flight can still land a great price for your trip.

How far in advance should I book a flight from Madrid to Santiago de los Caballeros?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 39 days in advance, which can save you up to 43% on flights from Madrid to Santiago de los Caballeros compared to booking the week you need them. Waiting 39 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $800. For sooner than that we have options available in the next 3 days from $892.

What is the cheapest month to fly from Madrid to Santiago de los Caballeros?

The best pricing can be found in the month of September. Prices to Santiago de los Caballeros from Madrid average $928. You can even find prices in September for less than $928, as users have found deals to Santiago de los Caballeros from as low as $686. The month of December appears to be one of the more expensive times to travel to Santiago de los Caballeros from Madrid. Flying in the targeted month can save you up to 48%.

How can I find direct flights from Madrid to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago de los Caballeros.

Can I find deals for business class flights from Madrid to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Madrid to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$547+ Flights from Madrid, Spain to Santiago de los Caballeros

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Madrid Barajas to Santiago de los Caballeros are usually found in September or October, booked 38 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Madrid to Santiago de los Caballeros

Round-trip from	$726 (JetBlue)
One-way from	$547 (Kiwi.com)
Popular in	December
Cheapest in	September
Average price	$978
Good one-way deal	$730 or less

From Madrid Barajas to Santiago de los Caballeros

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One-way flight from Madrid Barajas to Santiago de los Caballeros

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Highest demand for flights based on searches. 11% potential increase in price ($124 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Price to beat on a one-way flight from Madrid Barajas to Santiago de los Caballeros.

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Find flight deals from Madrid to Santiago de los Caballeros

Cheapest flights from Madrid to Santiago de los Caballeros
Explore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

mié. 10/11:30 pmMAD - STI

1 stop16h 29mJetBlue

mié. 10/1512:06 pmSTI - MAD

1 stop17h 24mJetBlue

Deal found 6/10

$726

mié. 11/1210:00 amMAD - STI

1 stop20h 26mDelta

jue. 1/298:11 pmSTI - MAD

1 stop30h 49mDelta

Deal found 6/11

$802

sáb. 7/55:25 pmMAD - STI

Nonstop8h 40mAir Europa

sáb. 7/2610:05 pmSTI - MAD

Nonstop8h 15mAir Europa

Deal found 6/10

$1,223

mar. 8/510:00 amMAD - STI

1 stop17h 19mAmerican Airlines

mié. 8/137:00 amSTI - MAD

1 stop18h 45mAmerican Airlines

Deal found 6/10

$1,408

jue. 6/2610:50 amMAD - STI

1 stop34h 22mUnited Airlines

lun. 6/304:23 pmSTI - MAD

2 stops42h 22mUnited Airlines

Deal found 6/10

$1,526

sáb. 7/510:35 amMAD - STI

3 stops29h 54mMultiple Airlines

sáb. 7/2610:55 amSTI - MAD

2 stops21h 35mMultiple Airlines

Deal found 6/10

$1,907

Best flights from Madrid to Santiago de los Caballeros
Discover carefully curated flight deals from Madrid to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 12, 2025.

mié. 10/11:30 pmMAD - STI

1 stop16h 29mJetBlue

mié. 10/1512:06 pmSTI - MAD

1 stop17h 24mJetBlue

Deal found 6/10

$726

mié. 11/1210:00 amMAD - STI

1 stop20h 26mDelta

jue. 1/298:11 pmSTI - MAD

1 stop30h 49mDelta

Deal found 6/11

$802

sáb. 7/55:25 pmMAD - STI

Nonstop8h 40mAir Europa

sáb. 7/2610:05 pmSTI - MAD

Nonstop8h 15mAir Europa

Deal found 6/10

$1,223

mar. 8/510:00 amMAD - STI

1 stop17h 19mAmerican Airlines

mié. 8/137:00 amSTI - MAD

1 stop18h 45mAmerican Airlines

Deal found 6/10

$1,408

jue. 6/2610:50 amMAD - STI

1 stop34h 22mUnited Airlines

lun. 6/304:23 pmSTI - MAD

2 stops42h 22mUnited Airlines

Deal found 6/10

$1,526

sáb. 7/510:35 amMAD - STI

3 stops29h 54mMultiple Airlines

sáb. 7/2610:55 amSTI - MAD

2 stops21h 35mMultiple Airlines

Deal found 6/10

$1,907

Last-minute flights from Madrid to Santiago de los Caballeros
Discover last-minute flight deals from Madrid to Santiago de los Caballeros. Data last updated junio 12, 2025 and is based on user searches.

sáb. 6/1412:40 pmMAD - STI

1 stop29h 59mDelta

sáb. 6/288:53 pmSTI - MAD

1 stop28h 57mDelta

Deal found 6/12

$1,091

jue. 6/261:30 pmMAD - STI

1 stop19h 58mJetBlue

jue. 7/311:15 amSTI - MAD

1 stop18h 15mJetBlue

Deal found 6/11

$1,154

jue. 6/2610:50 amMAD - STI

1 stop34h 22mUnited Airlines

lun. 6/304:23 pmSTI - MAD

2 stops42h 22mUnited Airlines

Deal found 6/10

$1,526

sáb. 7/55:25 pmMAD - STI

Nonstop8h 40mAir Europa

sáb. 7/2610:05 pmSTI - MAD

Nonstop8h 15mAir Europa

Deal found 6/10

$1,223

sáb. 7/510:00 amMAD - STI

1 stop17h 19mAmerican Airlines

sáb. 7/267:04 amSTI - MAD

1 stop18h 41mAmerican Airlines

Deal found 6/10

$1,454

sáb. 7/510:35 amMAD - STI

3 stops29h 54mMultiple Airlines

sáb. 7/2610:55 amSTI - MAD

2 stops21h 35mMultiple Airlines

Deal found 6/10

$1,907

One-way flights from Madrid to Santiago de los Caballeros
Search for one-way flight options from Madrid to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated junio 12, 2025.

vie. 7/112:45 pmMAD - STI

2 stops49h 05mMultiple Airlines

Deal found 6/12

$547

jue. 7/245:25 pmMAD - STI

Nonstop8h 40mAir Europa

Deal found 6/10

$777

lun. 6/3011:15 amMAD - STI

2 stops33h 57mUnited Airlines

Deal found 6/11

$1,018

mié. 7/231:30 pmMAD - STI

1 stop18h 08mJetBlue

Deal found 6/11

$1,026

Cheapflights Fare Finder

Use the filters below to find and compare flights from Madrid to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

mié. 10/1

1:30 pm-11:59 pm

1 stop16h 29m

Santiago de los Caballeros

mié. 10/15

12:06 pm-11:30 am

1 stop17h 24m

$726

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

mié. 11/12

10:00 am-1:26 am

1 stop20h 26m

Santiago de los Caballeros

jue. 1/29

8:11 pm-8:00 am

1 stop30h 49m

$802

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

sáb. 7/5

5:25 pm-8:05 pm

Nonstop8h 40m

Santiago de los Caballeros

sáb. 7/26

10:05 pm-12:20 pm

Nonstop8h 15m

$1,223

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

mar. 8/5

10:00 am-9:19 pm

1 stop17h 19m

Santiago de los Caballeros

mié. 8/13

7:00 am-7:45 am

1 stop18h 45m

$1,408

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

jue. 6/26

10:50 am-3:12 pm

1 stop34h 22m

Santiago de los Caballeros

lun. 6/30

4:23 pm-4:45 pm

2 stops42h 22m

$1,526

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

sáb. 7/5

10:35 am-10:29 am

3 stops29h 54m

Santiago de los Caballeros

sáb. 7/26

10:55 am-2:30 pm

2 stops21h 35m

$1,907

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

vie. 7/11

2:45 pm-9:50 am

2 stops49h 05m

$547

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

jue. 7/24

5:25 pm-8:05 pm

Nonstop8h 40m

$777

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

lun. 6/30

11:15 am-3:12 pm

2 stops33h 57m

$1,018

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

mié. 7/23

1:30 pm-1:38 am

1 stop18h 08m

$1,026

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Madrid to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Madrid with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago de los Caballeros

How far ahead should I book a flight from Madrid to Santiago de los Caballeros?

The best time to book flights from Madrid to Santiago de los Caballeros is 38 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago de los Caballeros (average of $347). Flying from Madrid to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to STI?

It’s optimal to fly from Madrid to Santiago de los Caballeros at noon. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the morning.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

2.0

Mediocre

Jake,Jan 2024

CVG - ATL

Would have been great but the flight got significantly delayed after we boarded due to a mechanical failure

Delta

8.0

Very good

7,950 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

2.0

Mediocre

Jake,Jan 2024

CVG - ATL

Would have been great but the flight got significantly delayed after we boarded due to a mechanical failure

United Airlines

7.4

Good

8,790 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

2.0

Mediocre

Jake,Jan 2024

CVG - ATL

Would have been great but the flight got significantly delayed after we boarded due to a mechanical failure

JetBlue

7.3

Good

2,925 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

2.0

Mediocre

Jake,Jan 2024

CVG - ATL

Would have been great but the flight got significantly delayed after we boarded due to a mechanical failure

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

2.0

Mediocre

Jake,Jan 2024

CVG - ATL

Would have been great but the flight got significantly delayed after we boarded due to a mechanical failure

Air Europa

6.9

Okay

529 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

2.0

Mediocre

Jake,Jan 2024

CVG - ATL

Would have been great but the flight got significantly delayed after we boarded due to a mechanical failure

Related info for your journey

What are the cheapest airlines flying from Madrid to Santiago de los Caballeros round-trip?
Flying on JetBlue is currently your cheapest option to Santiago de los Caballeros, with prices starting at $726. Additional round-trip tickets that might be worth considering are offered by Delta and Air Europa, with the lowest prices starting at $802 and $1,223, respectively. JetBlue is 21% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Madrid to Santiago de los Caballeros one-way?
To fly one-way, consider booking your trip with Air Europa, which is currently one of the cheapest options available, starting at $777. United Airlines flights start at $1,018 while deals on JetBlue start at $1,026 one-way.
What are the cheapest flights from Madrid to Santiago de los Caballeros?
The cheapest flight price from Madrid to Santiago de los Caballeros is $574. On average you can expect to pay $730. The most popular route, (Madrid Barajas - Santiago de los Caballeros), can usually be booked for $1,562.
Can I find deals for flights from Madrid to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Madrid to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Madrid to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago de los Caballeros.
Can I find deals for business class flights from Madrid to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Madrid to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago de los Caballeros (average of $347). Flying from Madrid to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Madrid to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
Air Europa	Cheapest$703	Average$1,013	FlexibilityNo cancel fee	On-time83%

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$547+ Cheap flights from Madrid, Spain (MAD) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Madrid to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Madrid Barajas to Santiago de los Caballeros are usually found in September or October, booked 38 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Madrid to Santiago de los Caballeros

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good one-way deal

Find flight deals from Madrid to Santiago de los Caballeros

Cheapest flights from Madrid to Santiago de los CaballerosExplore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Explore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Madrid to Santiago de los Caballeros that are best for you.

Best time to book a flight from Madrid to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Madrid with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago de los Caballeros

How far ahead should I book a flight from Madrid to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago de los Caballeros. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?

What is the cheapest time of day to fly from MAD to STI?

Find hourly flight availability from Madrid to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Madrid to Santiago de los Caballeros round-trip?

What are the cheapest airlines to fly from Madrid to Santiago de los Caballeros one-way?

What are the cheapest flights from Madrid to Santiago de los Caballeros?

Can I find deals for flights from Madrid to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Madrid to Santiago de los Caballeros?

Can I find deals for business class flights from Madrid to Santiago de los Caballeros?

What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Madrid to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Madrid to Santiago de los Caballeros

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Travel Smart

Cheapest flights from Madrid to Santiago de los Caballeros
Explore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.