How long is the flight from Madrid to Santiago de los Caballeros?

There are many flights that can get you from Madrid to Santiago de los Caballeros in 29h 43m. Fly via Delta to get the fastest option. The distance between Madrid and Santiago de los Caballeros is about 4163 mi.

What is the cheapest day to fly from Madrid to Santiago de los Caballeros?

Travelers seeking maximum savings on their Madrid to Santiago de los Caballeros flight should consider departing on Saturday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

How far in advance should I book a flight from Madrid to Santiago de los Caballeros?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 39 days in advance, which can save you up to 38% on flights from Madrid to Santiago de los Caballeros compared to booking the week you need them. Waiting 39 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $800. For sooner than that we have options available in the next 3 days from $892.

What is the cheapest month to fly from Madrid to Santiago de los Caballeros?

The best pricing can be found in the month of October. Prices to Santiago de los Caballeros from Madrid average $975. You can even find prices in October for less than $975, as users have found deals to Santiago de los Caballeros from as low as $700. The month of December appears to be one of the more expensive times to travel to Santiago de los Caballeros from Madrid. Flying in the targeted month can save you up to 42%.

How can I find direct flights from Madrid to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago de los Caballeros.

Can I find deals for business class flights from Madrid to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Madrid to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$595+ Flights from Madrid, Spain to Santiago de los Caballeros

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Madrid to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Madrid to Santiago de los Caballeros

Round-trip from	$842 (Delta)
One-way from	$595 (Kiwi.com)
Popular in	December
Cheapest in	October
Average price	$840
Good one-way deal	$605 or less

From Madrid Barajas to Santiago de los Caballeros

Search Deals

One-way flight from Madrid Barajas to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($110 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($38 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Price to beat on a one-way flight from Madrid Barajas to Santiago de los Caballeros.

Search Deals

Find flight deals from Madrid to Santiago de los Caballeros

Cheapest flights from Madrid to Santiago de los Caballeros
Explore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Sat 9/1312:40 pmMAD - STI

1 stop17h 54mDelta

Sat 9/278:40 pmSTI - MAD

1 stop29h 10mDelta

Deal found 9/11

$818

Mon 10/612:20 pmMAD - STI

2 stops29h 43mDelta

Mon 10/206:00 amSTI - MAD

1 stop19h 50mDelta

Deal found 9/11

$842

Sat 9/136:00 amMAD - STI

2 stops24h 34mDelta

Wed 10/151:29 pmSTI - MAD

2 stops20h 06mDelta

Deal found 9/10

$864

Wed 10/86:00 amMAD - STI

2 stops19h 06mDelta

Wed 10/228:31 pmSTI - MAD

1 stop29h 19mDelta

Deal found 9/11

$888

Wed 10/86:00 amMAD - STI

2 stops19h 06mDelta

Wed 10/158:31 pmSTI - MAD

1 stop29h 19mDelta

Deal found 9/10

$891

Tue 9/3012:20 pmMAD - STI

2 stops30h 20mDelta

Tue 10/76:00 amSTI - MAD

1 stop19h 50mDelta

Deal found 9/11

$901

Best flights from Madrid to Santiago de los Caballeros
Discover carefully curated flight deals from Madrid to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Mon 10/612:20 pmMAD - STI

2 stops29h 43mDelta

Mon 10/206:00 amSTI - MAD

2 stops21h 10mDelta

Deal found 9/11

$861

Thu 11/66:00 amMAD - STI

2 stops22h 51mUnited Airlines

Sat 12/612:52 pmSTI - MAD

2 stops38h 13mUnited Airlines

Deal found 9/10

$978

Wed 10/86:00 amMAD - STI

2 stops19h 06mDelta

Wed 10/221:29 pmSTI - MAD

2 stops20h 06mDelta

Deal found 9/11

$861

Wed 10/86:00 amMAD - STI

2 stops19h 06mDelta

Wed 10/158:31 pmSTI - MAD

1 stop29h 19mDelta

Deal found 9/10

$891

Tue 9/3012:20 pmMAD - STI

2 stops30h 20mDelta

Tue 10/76:00 amSTI - MAD

1 stop19h 50mDelta

Deal found 9/11

$901

Sat 12/66:00 amMAD - STI

2 stops24h 08mDelta

Fri 12/263:30 amSTI - MAD

1 stop23h 30mDelta

Deal found 9/10

$952

Sat 11/2210:00 amMAD - STI

2 stops19h 59mDelta

Fri 12/263:30 amSTI - MAD

1 stop23h 30mDelta

Deal found 9/10

$952

Last-minute flights from Madrid to Santiago de los Caballeros
Discover last-minute flight deals from Madrid to Santiago de los Caballeros. Data last updated September 11, 2025 and is based on user searches.

Sat 9/1312:40 pmMAD - STI

1 stop17h 54mDelta

Sat 9/278:40 pmSTI - MAD

1 stop29h 10mDelta

Deal found 9/11

$818

Sat 9/136:00 amMAD - STI

2 stops24h 34mDelta

Wed 10/151:29 pmSTI - MAD

2 stops20h 06mDelta

Deal found 9/10

$864

Tue 9/3012:20 pmMAD - STI

2 stops30h 20mDelta

Tue 10/76:00 amSTI - MAD

1 stop19h 50mDelta

Deal found 9/11

$901

Mon 10/612:20 pmMAD - STI

2 stops29h 43mDelta

Mon 10/206:00 amSTI - MAD

1 stop19h 50mDelta

Deal found 9/11

$842

Wed 10/86:00 amMAD - STI

2 stops19h 06mDelta

Wed 10/228:31 pmSTI - MAD

1 stop29h 19mDelta

Deal found 9/11

$888

Wed 10/86:00 amMAD - STI

2 stops19h 06mDelta

Wed 10/158:31 pmSTI - MAD

1 stop29h 19mDelta

Deal found 9/10

$891

One-way flights from Madrid to Santiago de los Caballeros
Search for one-way flight options from Madrid to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Sat 11/298:10 pmMAD - STI

3 stops49h 56mMultiple Airlines

Deal found 9/11

$595

Sat 11/293:25 pmMAD - STI

Nonstop8h 40mAir Europa

Deal found 9/11

$617

Tue 10/1411:15 amMAD - STI

2 stops33h 57mUnited Airlines

Deal found 9/9

$633

Sat 11/2911:15 amMAD - STI

1 stop17h 36mUnited Airlines

Deal found 9/11

$1,454

Cheapflights Fare Finder

Use the filters below to find and compare flights from Madrid to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Mon 10/6

12:20 pm-12:03 pm

2 stops29h 43m

Santiago de los Caballeros

Mon 10/20

6:00 am-9:10 am

2 stops21h 10m

$861

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Wed 10/8

6:00 am-7:06 pm

2 stops19h 06m

Santiago de los Caballeros

Wed 10/22

1:29 pm-3:35 pm

2 stops20h 06m

$861

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Wed 10/8

6:00 am-7:06 pm

2 stops19h 06m

Santiago de los Caballeros

Wed 10/15

8:31 pm-7:50 am

1 stop29h 19m

$891

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Tue 9/30

12:20 pm-12:40 pm

2 stops30h 20m

Santiago de los Caballeros

Tue 10/7

6:00 am-7:50 am

1 stop19h 50m

$901

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Sat 12/6

6:00 am-1:08 am

2 stops24h 08m

Santiago de los Caballeros

Fri 12/26

3:30 am-8:00 am

1 stop23h 30m

$952

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Sat 11/22

10:00 am-12:59 am

2 stops19h 59m

Santiago de los Caballeros

Fri 12/26

3:30 am-8:00 am

1 stop23h 30m

$952

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Thu 11/6

6:00 am-11:51 pm

2 stops22h 51m

Santiago de los Caballeros

Sat 12/6

12:52 pm-8:05 am

2 stops38h 13m

$978

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Sat 11/29

8:10 pm-5:06 pm

3 stops49h 56m

$595

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Sat 11/29

3:25 pm-7:05 pm

Nonstop8h 40m

$617

MadridSantiago de los Caballeros

MAD - STI

MADSTI

Madrid Barajas

Tue 10/14

11:15 am-3:12 pm

2 stops33h 57m

$633

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results

Best time to book a flight from Madrid to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Madrid with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago de los Caballeros

How far ahead should I book a flight from Madrid to Santiago de los Caballeros?

The best time to book flights from Madrid to Santiago de los Caballeros is 38 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago de los Caballeros (average of $347). Flying from Madrid to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to STI?

It’s optimal to fly from Madrid to Santiago de los Caballeros in the morning. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight at noon.

Related info for your journey

How long is the flight from Madrid to Santiago de los Caballeros?
There are many flights that can get you from Madrid to Santiago de los Caballeros in 29h 43m. Fly via Delta to get the fastest option. The distance between Madrid and Santiago de los Caballeros is about 4163 mi.
What are the cheapest flights from Madrid to Santiago de los Caballeros?
The cheapest flight price from Madrid to Santiago de los Caballeros is $562. On average you can expect to pay $605. The most popular route, (Madrid Barajas - Santiago de los Caballeros), can usually be booked for $1,023.
Can I find deals for flights from Madrid to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Madrid to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Madrid to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago de los Caballeros.
Can I find deals for business class flights from Madrid to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Madrid to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago de los Caballeros (average of $347). Flying from Madrid to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$595+ Cheap flights from Madrid, Spain (MAD) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Madrid to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Madrid to Santiago de los Caballeros

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good one-way deal

Find flight deals from Madrid to Santiago de los Caballeros

Cheapest flights from Madrid to Santiago de los CaballerosExplore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Madrid to Santiago de los Caballeros that are best for you.

Best time to book a flight from Madrid to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Madrid with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago de los Caballeros

How far ahead should I book a flight from Madrid to Santiago de los Caballeros?

What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?

What is the cheapest time of day to fly from MAD to STI?

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Madrid to Santiago de los Caballeros?

What are the cheapest flights from Madrid to Santiago de los Caballeros?

Can I find deals for flights from Madrid to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Madrid to Santiago de los Caballeros?

Can I find deals for business class flights from Madrid to Santiago de los Caballeros?

What is the cheapest month to book a flight from Madrid to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Madrid to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Madrid to Santiago de los Caballeros
Explore the most affordable flight options available from Madrid to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.