$168+ Cheap flights from Houston to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
Apr 19 — Apr 261
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santiago de los Caballeros
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Cheapest flights from Houston to Santiago de los CaballerosExplore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Fri 4/243:07 pm
STI
- IAH
1 stop8h 40m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$360
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Mon 5/113:07 pm
STI
- IAH
1 stop21h 17m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Sat 5/93:07 pm
STI
- IAH
1 stop8h 40m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:16 pm
IAH
- STI
1 stop24h 46m
Multiple Airlines
Sun 5/103:07 pm
STI
- IAH
1 stop24h 56m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:42 am
IAH
- STI
1 stop13h 07m
Multiple Airlines
Mon 4/133:28 pm
STI
- IAH
1 stop18h 12m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:29 am
IAH
- STI
1 stop28h 33m
Multiple Airlines
Thu 5/143:07 pm
STI
- IAH
1 stop24h 56m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
IAH
- STI
1 stop7h 02m
Multiple Airlines
Sun 5/103:07 pm
STI
- IAH
1 stop24h 56m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$385
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:30 pm
IAH
- STI
2 stops8h 19m
Spirit Airlines
Mon 4/203:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:50 pm
IAH
- STI
2 stops16h 12m
Multiple Airlines
Mon 5/113:07 pm
STI
- IAH
1 stop21h 17m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:50 pm
IAH
- STI
2 stops16h 12m
Multiple Airlines
Mon 5/113:07 pm
STI
- IAH
1 stop21h 17m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
HOU
- STI
2 stops17h 22m
Delta
Wed 5/66:00 am
STI
- HOU
2 stops11h 28m
Delta
Deal found 3/15![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
HOU
- STI
2 stops17h 59m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/16![Delta logo]()
$633
Best flights from Houston to Santiago de los CaballerosDiscover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
Discover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:05 am
IAH
- STI
1 stop16h 17m
Delta
Tue 5/126:00 am
STI
- IAH
1 stop11h 54m
Delta
Deal found 3/17![Delta logo]()
$609
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:12 pm
IAH
- STI
2 stops17h 11m
American Airlines
Wed 5/201:32 pm
STI
- IAH
2 stops20h 04m
American Airlines
Deal found 3/15![American Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:14 pm
IAH
- STI
1 stop9h 38m
United Airlines
Tue 5/52:07 pm
STI
- IAH
1 stop10h 35m
United Airlines
Deal found 3/16![United Airlines logo]()
$629
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:20 am
IAH
- STI
2 stops18h 39m
Delta
Wed 7/156:15 am
STI
- IAH
2 stops16h 44m
Delta
Deal found 3/17![Delta logo]()
$613
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:32 am
IAH
- STI
1 stop6h 11m
American Airlines
Mon 8/101:31 pm
STI
- IAH
1 stop11h 57m
American Airlines
Deal found 3/19![American Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:14 pm
IAH
- STI
1 stop9h 38m
United Airlines
Tue 5/52:07 pm
STI
- IAH
1 stop10h 35m
United Airlines
Deal found 3/19![United Airlines logo]()
$629
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:48 am
IAH
- STI
2 stops13h 34m
Delta
Tue 5/126:00 am
STI
- IAH
2 stops12h 30m
Delta
Deal found 3/18![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
IAH
- STI
2 stops11h 33m
Delta
Thu 5/148:59 pm
STI
- IAH
2 stops14h 40m
Delta
Deal found 3/18![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:05 am
IAH
- STI
2 stops10h 28m
Delta
Wed 5/136:00 am
STI
- IAH
2 stops13h 27m
Delta
Deal found 3/17![Delta logo]()
$613
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/16![American Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
IAH
- STI
1 stop11h 28m
Delta
Wed 5/136:00 am
STI
- IAH
1 stop11h 54m
Delta
Deal found 3/17![Delta logo]()
$629
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
HOU
- STI
2 stops17h 59m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/16![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:53 am
HOU
- STI
2 stops12h 29m
Delta
Tue 4/216:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 3/18![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
HOU
- STI
2 stops12h 28m
Delta
Mon 5/118:59 pm
STI
- HOU
2 stops16h 12m
Delta
Deal found 3/18![Delta logo]()
$653
Last-minute flights from Houston to Santiago de los CaballerosDiscover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated March 20, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated March 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:14 am
HOU
- STI
2 stops9h 15m
American Airlines
Tue 3/247:00 am
STI
- HOU
2 stops13h 50m
American Airlines
Deal found 3/19![American Airlines logo]()
$1,193
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:42 am
IAH
- STI
1 stop13h 07m
Multiple Airlines
Mon 4/133:28 pm
STI
- IAH
1 stop18h 12m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:42 am
IAH
- STI
1 stop13h 07m
Multiple Airlines
Mon 4/63:28 pm
STI
- IAH
2 stops17h 01m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$396
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Sun 4/122:46 am
STI
- IAH
2 stops8h 32m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 am
HOU
- STI
2 stops13h 29m
American Airlines
Mon 4/61:30 pm
STI
- HOU
2 stops11h 28m
American Airlines
Deal found 3/19![American Airlines logo]()
$963
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:35 am
IAH
- STI
1 stop5h 48m
Spirit Airlines
Mon 4/133:28 pm
STI
- IAH
1 stop18h 12m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/16![American Airlines logo]()
$758
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Mon 4/203:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:53 am
HOU
- STI
2 stops12h 29m
Delta
Tue 4/216:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 3/18![Delta logo]()
$633
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Fri 4/243:07 pm
STI
- IAH
1 stop8h 40m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
HOU
- STI
2 stops17h 22m
Delta
Wed 5/66:00 am
STI
- HOU
2 stops11h 28m
Delta
Deal found 3/15![Delta logo]()
$613
One-way flights from Houston to Santiago de los CaballerosSearch for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
Search for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
This Trip.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$168
This Mytrip deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$176
This Trip.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:26 am
IAH
- STI
1 stop15h 23m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$212
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:00 am
IAH
- STI
1 stop6h 50m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$230
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:30 pm
IAH
- STI
2 stops8h 19m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$231
This Booking.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:45 am
IAH
- STI
1 stop7h 50m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:29 am
IAH
- STI
1 stop28h 33m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$237
This Super.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
HOU
- STI
2 stops17h 22m
Delta
Deal found 3/15![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Deal found 3/15![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Deal found 3/17![American Airlines logo]()
$425
Find flight deals from Houston to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 20, 2026.
Round-trip from | $360 (CheapOair) |
|---|---|
One-way from | $168 (Trip.com) |
Popular in | August |
Cheapest in | October |
Average price | $573 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Tue 5/5
7:05 am-12:22 am
1 stop16h 17m
Santiago de los Caballeros
Tue 5/12
6:00 am-4:54 pm
1 stop11h 54m
$609
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Thu 5/7
6:12 pm-12:23 pm
2 stops17h 11m
Santiago de los Caballeros
Wed 5/20
1:32 pm-8:36 am
2 stops20h 04m
$613
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Mon 6/1
5:20 am-12:59 am
2 stops18h 39m
Santiago de los Caballeros
Wed 7/15
6:15 am-9:59 pm
2 stops16h 44m
$613
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/6
9:48 am-12:22 am
2 stops13h 34m
Santiago de los Caballeros
Tue 5/12
6:00 am-5:30 pm
2 stops12h 30m
$613
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/6
7:00 am-7:33 pm
2 stops11h 33m
Santiago de los Caballeros
Thu 5/14
8:59 pm-10:39 am
2 stops14h 40m
$613
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/6
8:05 am-7:33 pm
2 stops10h 28m
Santiago de los Caballeros
Wed 5/13
6:00 am-6:27 pm
2 stops13h 27m
$613
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 5/2
12:14 pm-10:52 pm
1 stop9h 38m
Santiago de los Caballeros
Tue 5/5
2:07 pm-11:42 pm
1 stop10h 35m
$629
Quickest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 7/29
7:32 am-2:43 pm
1 stop6h 11m
Santiago de los Caballeros
Mon 8/10
1:31 pm-12:28 am
1 stop11h 57m
$629
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Fri 5/1
12:14 pm-10:52 pm
1 stop9h 38m
Santiago de los Caballeros
Tue 5/5
2:07 pm-11:42 pm
1 stop10h 35m
$629
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Thu 5/7
7:00 am-7:28 pm
1 stop11h 28m
Santiago de los Caballeros
Wed 5/13
6:00 am-4:54 pm
1 stop11h 54m
$629
Showing 1-10 of 28 resultsSorted by cheapest first
Best time to book a flight from Houston to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
HO1-STI
IAH-STI
HOU-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santiago de los Caballeros
HO1-STI
IAH-STI
HOU-STI
What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston to Santiago de los Caballeros?
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated March 20, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Crew
7.9
Food
6.4
Overall
7.1
Entertainment
6.9
Comfort
7.2
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Boarding
7.5
Crew
7.9
Food
6.4
Overall
7.1
Entertainment
6.9
Comfort
7.2
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Boarding
7.5
Crew
7.9
Food
6.4
Overall
7.1
Entertainment
6.9
Comfort
7.2
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Related info for your journey
Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago de los Caballeros flight routes
Alternative routes for Houston to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santiago de los Caballeros by cabin class
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Houston and Santiago de los Caballeros flights
Browse other Houston and Santiago de los Caballeros flight options. Last updated on March 20, 2026.
Popular flight searches
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Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 20, 2026.
Top 2 airlines flying from Houston to Santiago de los Caballeros
Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$265 | Average$424 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$514 | Average$751 | FlexibilityNo cancel fee | On-time71% |