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Santiago de los Caballeros

$154+ Cheap flights from Houston to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
Mar 16 — Mar 231
Mon 3/16
Mon 3/23
1 adult, Economy
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Cheap flight deals from Houston to Santiago de los Caballeros

Cheapest flights from Houston to Santiago de los Caballeros
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.

This Mytrip deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:27 pm
IAH
-
STI
1 stop6h 22m
Spirit Airlines
Mon 3/302:46 am
STI
-
IAH
1 stop6h 54m
Spirit Airlines
Deal found 2/10$315
This Cheapflightsfares deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:27 pm
IAH
-
STI
1 stop6h 22m
Spirit Airlines
Wed 4/153:40 pm
STI
-
IAH
1 stop18h 05m
Spirit Airlines
Deal found 2/14$316
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:46 am
IAH
-
STI
1 stop7h 49m
Spirit Airlines
Sat 2/214:40 pm
STI
-
IAH
1 stop17h 20m
Spirit Airlines
Deal found 2/11$337
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:41 pm
IAH
-
STI
1 stop22h 54m
Multiple Airlines
Mon 2/234:40 pm
STI
-
IAH
1 stop17h 20m
Multiple Airlines
Deal found 2/10$339
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:46 am
IAH
-
STI
1 stop7h 49m
Spirit Airlines
Thu 3/54:40 pm
STI
-
IAH
1 stop9h 38m
Spirit Airlines
Deal found 2/11$341
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:46 am
IAH
-
STI
1 stop7h 49m
Spirit Airlines
Tue 2/244:40 pm
STI
-
IAH
1 stop17h 20m
Spirit Airlines
Deal found 2/11$349
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/204:22 pm
IAH
-
STI
1 stop21h 13m
Spirit Airlines
Mon 2/234:40 pm
STI
-
IAH
1 stop17h 20m
Spirit Airlines
Deal found 2/11$360
This WAYA deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:45 am
IAH
-
STI
1 stop7h 50m
Spirit Airlines
Sat 4/43:28 pm
STI
-
IAH
1 stop9h 31m
Spirit Airlines
Deal found 2/10$368
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:22 pm
HOU
-
STI
2 stops17h 40m
Delta
Tue 3/246:33 am
STI
-
HOU
2 stops17h 09m
Delta
Deal found 2/13$553
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:19 pm
HOU
-
STI
2 stops19h 04m
American Airlines
Sun 5/171:32 pm
STI
-
HOU
2 stops20h 54m
American Airlines
Deal found 2/13$578
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am
HOU
-
STI
2 stops16h 55m
Delta
Mon 11/169:00 pm
STI
-
HOU
2 stops21h 30m
Delta
Deal found 2/11$593
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:21 pm
HOU
-
STI
2 stops17h 17m
American Airlines
Thu 5/287:03 am
STI
-
HOU
2 stops12h 06m
American Airlines
Deal found 2/10$598

Find flight deals from Houston to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 14, 2026.

Round-trip from

$315
(Mytrip)

One-way from

$154
(Trip.com)

Popular in

August

Cheapest in

October

Average price

$408
From Houston to Santiago de los Caballeros
Search Deals
One-way flight from Houston to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Houston

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 3/17

6:27 pm-1:49 am

1 stop6h 22m

Santiago de los Caballeros

Mon 3/30

2:46 am-8:40 am

1 stop6h 54m

$315

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 4/8

6:27 pm-1:49 am

1 stop6h 22m

Santiago de los Caballeros

Wed 4/15

3:40 pm-8:45 am

1 stop18h 05m

$316

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sun 3/1

5:46 am-3:35 pm

1 stop7h 49m

Santiago de los Caballeros

Thu 3/5

4:40 pm-12:18 am

1 stop9h 38m

$341

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Thu 4/23

7:35 am-2:35 pm

1 stop6h 00m

Santiago de los Caballeros

Sat 5/2

3:40 pm-11:59 pm

1 stop9h 19m

$364

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Mon 3/23

5:45 am-2:35 pm

1 stop7h 50m

Santiago de los Caballeros

Sat 4/4

3:28 pm-11:59 pm

1 stop9h 31m

$368

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 3/17

6:27 pm-1:49 am

1 stop6h 22m

Santiago de los Caballeros

Tue 3/24

3:43 pm-8:40 am

1 stop17h 57m

$381

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 5/6

6:00 am-12:22 am

2 stops17h 22m

Santiago de los Caballeros

Tue 5/12

8:59 pm-12:11 pm

2 stops16h 12m

$553

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Mon 5/11

4:19 pm-12:23 pm

2 stops19h 04m

Santiago de los Caballeros

Sun 5/17

1:32 pm-9:26 am

2 stops20h 54m

$578

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 5/20

8:21 pm-2:38 pm

2 stops17h 17m

Santiago de los Caballeros

Thu 5/28

7:03 am-6:09 pm

2 stops12h 06m

$598

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 4/8

4:18 pm-12:23 pm

2 stops19h 05m

Santiago de los Caballeros

Wed 4/15

1:32 pm-11:47 pm

2 stops11h 15m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 33 results
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Best time to book a flight from Houston to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago de los Caballeros

What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?

Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated February 14, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,288 reviews

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
11,288 reviews
American Airlines
7.2
Good
11,288 reviews

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
Spirit Airlines
6.3
Okay
8,451 reviews
American Airlines
7.2
Good
11,288 reviews

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from Houston?

    Santiago de los Caballeros (STI), located 6.8 mi from the city center, is the airport you fly into when you book flights from Houston to Santiago de los Caballeros. 2 airlines have flights to Santiago from Houston on a regular basis. Booking flights from Houston to Santiago de los Caballeros should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santiago de los Caballeros?

    Departing from Houston to Santiago de los Caballeros will take you 6h 22m. There are 1710 mi between Houston and Santiago de los Caballeros. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Houston to Santiago de los Caballeros round-trip?

    Currently priced at $265, Spirit Airlines will fly you from Houston to Santiago de los Caballeros and back. In addition to Spirit Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $514. You may be able to fly from Houston to Santiago de los Caballeros for 55% less than the average price by searching for these airlines.

  • Can I find deals for flights from Houston to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago de los Caballeros.

  • Can I find deals for business class flights from Houston to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Houston to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?

    Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Houston to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$265Average$423FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$514Average$768FlexibilityNo cancel feeOn-time71%

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