$212+ Cheap flights from Houston to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
Apr 23 — Apr 301
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santiago de los Caballeros
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Cheapest flights from Houston to Santiago de los CaballerosExplore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Mon 5/113:07 pm
STI
- IAH
1 stop8h 40m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Sun 4/263:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
IAH
- STI
1 stop7h 02m
Multiple Airlines
Mon 5/113:07 pm
STI
- IAH
2 stops24h 51m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:16 pm
IAH
- STI
1 stop24h 46m
Multiple Airlines
Sun 5/33:07 pm
STI
- IAH
2 stops32h 43m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$404
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Thu 5/283:07 pm
STI
- IAH
1 stop21h 17m
Spirit Airlines
Deal found 3/21![Spirit Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:42 am
IAH
- STI
1 stop13h 07m
Multiple Airlines
Sun 4/52:46 am
STI
- IAH
2 stops39h 12m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$426
This Trip.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:02 pm
IAH
- STI
1 stop12h 47m
Multiple Airlines
Sat 4/112:46 am
STI
- IAH
1 stop16h 07m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:29 am
IAH
- STI
1 stop28h 33m
Multiple Airlines
Mon 6/83:07 pm
STI
- IAH
1 stop24h 44m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Sun 5/33:07 pm
STI
- IAH
1 stop21h 17m
Spirit Airlines
Deal found 3/19![Spirit Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:27 am
HOU
- STI
2 stops13h 32m
Delta
Thu 5/146:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/23![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:15 pm
HOU
- STI
2 stops19h 05m
American Airlines
Sat 9/261:40 pm
STI
- HOU
2 stops20h 19m
American Airlines
Deal found 3/19![American Airlines logo]()
$653
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:06 pm
HOU
- STI
2 stops10h 53m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/20![Delta logo]()
$678
Best flights from Houston to Santiago de los CaballerosDiscover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
Discover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:27 pm
IAH
- STI
2 stops24h 35m
Multiple Airlines
Mon 6/13:07 pm
STI
- IAH
1 stop21h 17m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$516
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:46 pm
IAH
- STI
1 stop18h 16m
Spirit Airlines
Sun 5/313:07 pm
STI
- IAH
1 stop21h 17m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:39 pm
IAH
- STI
1 stop11h 20m
Delta
Thu 6/116:00 am
STI
- IAH
1 stop16h 45m
Delta
Deal found 3/22![Delta logo]()
$609
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:14 pm
IAH
- STI
1 stop19h 24m
American Airlines
Wed 7/159:00 am
STI
- IAH
1 stop15h 59m
American Airlines
Deal found 3/19![American Airlines logo]()
$623
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:30 pm
IAH
- STI
2 stops8h 19m
Spirit Airlines
Sat 4/112:46 am
STI
- IAH
3 stops32h 32m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:39 pm
IAH
- STI
1 stop11h 20m
Delta
Sat 6/66:00 am
STI
- IAH
1 stop10h 52m
Delta
Deal found 3/22![Delta logo]()
$629
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:00 am
IAH
- STI
2 stops15h 15m
American Airlines
Mon 8/107:00 am
STI
- IAH
1 stop14h 37m
American Airlines
Deal found 3/19![American Airlines logo]()
$633
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:06 pm
HOU
- STI
2 stops10h 53m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/19![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:08 pm
IAH
- STI
2 stops21h 12m
American Airlines
Sat 9/261:40 pm
STI
- IAH
2 stops20h 05m
American Airlines
Deal found 3/19![American Airlines logo]()
$653
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:27 am
HOU
- STI
2 stops13h 32m
Delta
Thu 5/146:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/23![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:12 pm
IAH
- STI
1 stop19h 32m
American Airlines
Mon 7/273:44 pm
STI
- IAH
1 stop20h 36m
American Airlines
Deal found 3/19![American Airlines logo]()
$657
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
IAH
- STI
2 stops16h 22m
Delta
Tue 5/56:00 am
STI
- IAH
2 stops12h 42m
Delta
Deal found 3/23![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:21 pm
HOU
- STI
2 stops15h 02m
American Airlines
Sun 5/101:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/19![American Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/20![American Airlines logo]()
$848
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
HOU
- STI
2 stops17h 47m
Delta
Mon 8/178:53 pm
STI
- HOU
2 stops20h 30m
Delta
Deal found 3/24![Delta logo]()
$967
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
HOU
- STI
2 stops17h 22m
Delta
Sun 4/268:59 pm
STI
- HOU
2 stops16h 41m
Delta
Deal found 3/24![Delta logo]()
$992
Last-minute flights from Houston to Santiago de los CaballerosDiscover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated March 24, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated March 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:42 am
IAH
- STI
1 stop13h 07m
Multiple Airlines
Sun 4/52:46 am
STI
- IAH
2 stops39h 12m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$426
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:30 pm
IAH
- STI
2 stops8h 19m
Spirit Airlines
Sun 4/52:46 am
STI
- IAH
2 stops8h 32m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$523
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:27 pm
HOU
- STI
2 stops17h 35m
Delta
Mon 4/66:00 am
STI
- HOU
2 stops17h 42m
Delta
Deal found 3/22![Delta logo]()
$1,191
This Trip.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:02 pm
IAH
- STI
1 stop12h 47m
Multiple Airlines
Sat 4/112:46 am
STI
- IAH
1 stop16h 07m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:14 am
HOU
- STI
2 stops9h 15m
American Airlines
Sun 4/121:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/23![American Airlines logo]()
$1,283
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/24![American Airlines logo]()
$848
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Sun 4/263:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
HOU
- STI
2 stops17h 22m
Delta
Sun 4/268:59 pm
STI
- HOU
2 stops16h 41m
Delta
Deal found 3/24![Delta logo]()
$992
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:16 pm
IAH
- STI
1 stop24h 46m
Multiple Airlines
Sun 5/33:07 pm
STI
- IAH
2 stops32h 43m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Sun 5/33:07 pm
STI
- IAH
1 stop21h 17m
Spirit Airlines
Deal found 3/19![Spirit Airlines logo]()
$439
One-way flights from Houston to Santiago de los CaballerosSearch for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
Search for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$212
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:00 am
IAH
- STI
1 stop6h 50m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:29 am
IAH
- STI
1 stop28h 33m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$237
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Deal found 3/19![Spirit Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:45 am
IAH
- STI
2 stops31h 17m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:12 pm
IAH
- STI
2 stops40h 50m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$260
This Super.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Deal found 3/19![Spirit Airlines logo]()
$265
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 am
IAH
- STI
1 stop6h 50m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$270
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$272
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Deal found 3/20![American Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Deal found 3/23![American Airlines logo]()
$452
Find flight deals from Houston to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 24, 2026.
Round-trip from | $360 (CheapOair) |
|---|---|
One-way from | $212 (CheapOair) |
Popular in | August |
Cheapest in | October |
Average price | $573 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Thu 5/21
12:27 pm-2:02 pm
2 stops24h 35m
Santiago de los Caballeros
Mon 6/1
3:07 pm-11:24 am
1 stop21h 17m
$516
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 5/23
6:46 pm-2:02 pm
1 stop18h 16m
Santiago de los Caballeros
Sun 5/31
3:07 pm-11:24 am
1 stop21h 17m
$517
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 4/4
4:30 pm-1:49 am
2 stops8h 19m
Santiago de los Caballeros
Sat 4/11
2:46 am-10:18 am
3 stops32h 32m
$581
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Tue 5/26
12:39 pm-12:59 am
1 stop11h 20m
Santiago de los Caballeros
Thu 6/11
6:00 am-9:45 pm
1 stop16h 45m
$609
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Mon 6/15
6:14 pm-2:38 pm
1 stop19h 24m
Santiago de los Caballeros
Wed 7/15
9:00 am-11:59 pm
1 stop15h 59m
$623
Quickest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Tue 5/26
12:39 pm-12:59 am
1 stop11h 20m
Santiago de los Caballeros
Sat 6/6
6:00 am-3:52 pm
1 stop10h 52m
$629
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 7/29
5:00 am-9:15 pm
2 stops15h 15m
Santiago de los Caballeros
Mon 8/10
7:00 am-8:37 pm
1 stop14h 37m
$633
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Thu 5/7
1:06 pm-12:59 am
2 stops10h 53m
Santiago de los Caballeros
Wed 5/20
6:00 am-10:26 pm
2 stops17h 26m
$633
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Thu 5/7
10:27 am-12:59 am
2 stops13h 32m
Santiago de los Caballeros
Thu 5/14
6:00 am-10:26 pm
2 stops17h 26m
$633
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 5/2
7:00 am-12:22 am
2 stops16h 22m
Santiago de los Caballeros
Tue 5/5
6:00 am-5:42 pm
2 stops12h 42m
$633
Showing 1-10 of 31 resultsSorted by cheapest first
Best time to book a flight from Houston to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
HO1-STI
IAH-STI
HOU-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santiago de los Caballeros
HO1-STI
IAH-STI
HOU-STI
What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated March 24, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Entertainment
6.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Crew
7.9
Entertainment
6.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Crew
7.9
Entertainment
6.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Related info for your journey
Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago de los Caballeros flight routes
Alternative routes for Houston to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santiago de los Caballeros by cabin class
Find flights from Houston to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Santiago de los Caballeros flights
Browse other Houston and Santiago de los Caballeros flight options. Last updated on March 24, 2026.
Popular flight searches
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Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 24, 2026.
Top 2 airlines flying from Houston to Santiago de los Caballeros
Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$265 | Average$424 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$514 | Average$751 | FlexibilityNo cancel fee | On-time71% |