Santiago de los Caballeros

$241+ Cheap flights from Houston to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
Dec 9 — Dec 161
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Houston to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Houston to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2025.

Round-trip from

$287
(Cheapflightsfares)

One-way from

$241
(Trip.com)

Popular in

August

Cheapest in

October

Average price

$590
From Houston to Santiago de los Caballeros
One-way flight from Houston to Santiago de los Caballeros
Highest demand for flights based on searches. 3% potential increase in price ($22 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
Average for round-trip flights in November 2025

Find flight deals from Houston to Santiago de los Caballeros

Cheapest flights from Houston to Santiago de los Caballeros
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:41 amIAH - STI
1 stop14h 01mSpirit Airlines
Sun 12/143:43 amSTI - IAH
1 stop7h 35mSpirit Airlines
Deal found 11/8$287
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:41 amIAH - STI
1 stop14h 01mSpirit Airlines
Mon 12/153:43 amSTI - IAH
1 stop16h 00mSpirit Airlines
Deal found 11/9$295
This Cheapflightsfares deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:09 pmIAH - STI
1 stop16h 13mSpirit Airlines
Mon 12/83:43 amSTI - IAH
1 stop16h 00mSpirit Airlines
Deal found 11/8$300
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:25 pmIAH - STI
1 stop14h 41mSpirit Airlines
Sun 12/143:43 amSTI - IAH
1 stop7h 35mSpirit Airlines
Deal found 11/9$325
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:42 pmHOU - STI
2 stops18h 50mAmerican Airlines
Wed 12/104:32 pmSTI - HOU
2 stops19h 09mAmerican Airlines
Deal found 11/7$567
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amHOU - STI
2 stops17h 08mDelta
Tue 12/168:57 pmSTI - HOU
2 stops18h 31mDelta
Deal found 11/9$717
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/169:05 amHOU - STI
2 stops9h 46mAmerican Airlines
Fri 11/286:20 amSTI - HOU
2 stops15h 30mAmerican Airlines
Deal found 11/8$767
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:36 pmHOU - STI
2 stops18h 56mAmerican Airlines
Mon 12/156:00 amSTI - HOU
2 stops16h 18mAmerican Airlines
Deal found 11/9$772
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amHOU - STI
2 stops12h 51mAmerican Airlines
Mon 11/177:00 amSTI - HOU
2 stops12h 54mAmerican Airlines
Deal found 11/7$812
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amHOU - STI
2 stops16h 59mDelta
Thu 11/276:40 amSTI - HOU
2 stops18h 27mDelta
Deal found 11/7$822
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:48 pmHOU - STI
2 stops16h 18mDelta
Mon 11/176:40 amSTI - HOU
2 stops18h 27mDelta
Deal found 11/8$832
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:00 amHOU - STI
2 stops16h 59mDelta
Thu 11/206:40 amSTI - HOU
2 stops19h 00mDelta
Deal found 11/9$912

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 9, 2025.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Houston

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Mon 12/8

10:41 am-2:42 am

1 stop14h 01m

Santiago de los Caballeros

Sun 12/14

3:43 am-9:18 am

1 stop7h 35m

$287

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sun 2/22

7:35 am-3:35 pm

1 stop6h 00m

Santiago de los Caballeros

Thu 2/26

4:40 pm-12:04 am

1 stop9h 24m

$329

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Fri 12/12

10:41 am-2:42 am

1 stop14h 01m

Santiago de los Caballeros

Sun 12/14

3:43 am-9:18 am

1 stop7h 35m

$346

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Mon 2/23

7:35 am-3:35 pm

1 stop6h 00m

Santiago de los Caballeros

Fri 2/27

4:40 pm-12:04 am

1 stop9h 24m

$349

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 12/9

5:20 am-2:42 am

2 stops19h 22m

Santiago de los Caballeros

Mon 12/15

3:43 am-7:04 am

3 stops29h 21m

$351

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 12/2

12:14 pm-12:22 pm

2 stops22h 08m

Santiago de los Caballeros

Mon 12/8

3:43 am-5:43 pm

1 stop16h 00m

$367

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sun 1/11

6:36 pm-3:32 pm

2 stops18h 56m

Santiago de los Caballeros

Sun 1/18

6:00 am-4:12 pm

2 stops12h 12m

$567

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Tue 12/9

6:00 am-1:08 am

2 stops17h 08m

Santiago de los Caballeros

Tue 12/16

8:57 pm-1:28 pm

2 stops18h 31m

$717

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sun 11/16

9:05 am-8:51 pm

2 stops9h 46m

Santiago de los Caballeros

Fri 11/28

6:20 am-7:50 pm

2 stops15h 30m

$767

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Fri 12/12

6:36 pm-3:32 pm

2 stops18h 56m

Santiago de los Caballeros

Mon 12/15

6:00 am-8:18 pm

2 stops16h 18m

$772

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/7

Showing 1-10 of 20 results
1
2

Best time to book a flight from Houston to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago de los Caballeros

What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?

Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in May is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to STI?

Find hourly flight availability from Houston to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 9, 2025.

One of the essential ways to save on airfare from Houston to Santiago de los Caballeros is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 56% on airfare.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated November 9, 2025.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santiago de los Caballeros from Houston?

    Santiago de los Caballeros (STI), located 6.8 mi from the city center, is the airport you fly into when you book flights from Houston to Santiago de los Caballeros. 2 airlines have flights to Santiago from Houston on a regular basis. Booking flights from Houston to Santiago de los Caballeros should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santiago de los Caballeros?

    Departing from Houston to Santiago de los Caballeros will take you 14h 01m. There are 1710 mi between Houston and Santiago de los Caballeros. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Houston to Santiago de los Caballeros round-trip?

    Currently priced at $298, Spirit Airlines will fly you from Houston to Santiago de los Caballeros and back. In addition to Spirit Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $514. You may be able to fly from Houston to Santiago de los Caballeros for 53% less than the average price by searching for these airlines.

  • Can I find deals for flights from Houston to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago de los Caballeros.

  • Can I find deals for business class flights from Houston to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Houston to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?

    Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in May is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Houston to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$298Average$423FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$514Average$785FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.