$169+ Cheap flights from Houston to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
May 8 — May 151
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santiago de los Caballeros
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Cheapest flights from Houston to Santiago de los CaballerosExplore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 4/5![Spirit Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Sat 5/23:07 pm
STI
- IAH
1 stop24h 56m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Sun 4/263:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 4/5![Spirit Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:17 pm
IAH
- STI
2 stops23h 45m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 4/5![Spirit Airlines logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Sun 4/263:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop8h 40m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$426
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
HOU
- STI
2 stops17h 59m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 4/3![Delta logo]()
$635
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:23 pm
HOU
- STI
2 stops17h 47m
Delta
Sun 5/36:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 4/6![Delta logo]()
$725
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Fri 5/227:03 am
STI
- HOU
2 stops12h 06m
American Airlines
Deal found 4/4![American Airlines logo]()
$735
Best flights from Houston to Santiago de los CaballerosDiscover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 8, 2026.
Discover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Sat 5/23:07 pm
STI
- IAH
1 stop8h 40m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2612:35 pm
IAH
- STI
2 stops24h 27m
Spirit Airlines
Sat 5/23:07 pm
STI
- IAH
1 stop8h 40m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$428
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:38 pm
IAH
- STI
1 stop10h 44m
Delta
Wed 5/138:59 pm
STI
- IAH
1 stop15h 16m
Delta
Deal found 4/7![Delta logo]()
$610
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:57 am
IAH
- STI
1 stop10h 55m
United Airlines
Thu 10/12:07 pm
STI
- IAH
1 stop10h 43m
United Airlines
Deal found 4/4![United Airlines logo]()
$610
This Expedia deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 pm
IAH
- STI
2 stops22h 13m
JetBlue
Sun 8/233:51 pm
STI
- IAH
2 stops26h 13m
JetBlue
Deal found 4/6![JetBlue logo]()
$679
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Fri 5/227:03 am
STI
- HOU
2 stops12h 06m
American Airlines
Deal found 4/4![American Airlines logo]()
$735
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:50 pm
IAH
- STI
2 stops41h 30m
Multiple Airlines
Sat 5/93:17 pm
STI
- IAH
1 stop18h 46m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$453
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:45 am
IAH
- STI
1 stop8h 35m
Spirit Airlines
Mon 5/184:15 pm
STI
- IAH
3 stops31h 01m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:39 pm
IAH
- STI
1 stop11h 20m
Delta
Tue 5/128:59 pm
STI
- IAH
1 stop15h 16m
Delta
Deal found 4/4![Delta logo]()
$630
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
HOU
- STI
2 stops17h 59m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 4/3![Delta logo]()
$635
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
HOU
- STI
2 stops17h 22m
Delta
Mon 5/116:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 4/4![Delta logo]()
$635
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:06 pm
HOU
- STI
2 stops10h 53m
Delta
Tue 5/128:59 pm
STI
- HOU
2 stops16h 12m
Delta
Deal found 4/4![Delta logo]()
$635
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:37 pm
IAH
- STI
1 stop12h 18m
Delta
Mon 7/271:52 pm
STI
- IAH
2 stops19h 43m
Delta
Deal found 4/4![Delta logo]()
$680
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:23 pm
HOU
- STI
2 stops17h 47m
Delta
Sun 5/36:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 4/6![Delta logo]()
$725
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
HOU
- STI
2 stops17h 59m
Delta
Sat 6/138:59 pm
STI
- HOU
2 stops16h 14m
Delta
Deal found 4/3![Delta logo]()
$880
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
HOU
- STI
2 stops18h 59m
Delta
Mon 6/158:59 pm
STI
- HOU
2 stops20h 28m
Delta
Deal found 4/7![Delta logo]()
$1,958
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:09 am
HOU
- STI
2 stops14h 50m
Delta
Thu 6/258:59 pm
STI
- HOU
2 stops20h 28m
Delta
Deal found 4/5![Delta logo]()
$2,275
Last-minute flights from Houston to Santiago de los CaballerosDiscover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated April 8, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated April 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 4/5![Spirit Airlines logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Sun 4/263:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 4/5![Spirit Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Sun 4/263:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 4/5![Spirit Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:17 pm
IAH
- STI
2 stops23h 45m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:14 pm
IAH
- STI
2 stops18h 48m
Multiple Airlines
Mon 4/273:07 pm
STI
- IAH
1 stop8h 40m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Sat 5/23:07 pm
STI
- IAH
1 stop24h 56m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:23 pm
HOU
- STI
2 stops17h 47m
Delta
Sun 5/36:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 4/6![Delta logo]()
$725
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
HOU
- STI
2 stops17h 59m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 4/3![Delta logo]()
$635
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Fri 5/227:03 am
STI
- HOU
2 stops12h 06m
American Airlines
Deal found 4/4![American Airlines logo]()
$735
One-way flights from Houston to Santiago de los CaballerosSearch for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 8, 2026.
Search for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:16 pm
IAH
- STI
1 stop24h 46m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:15 am
IAH
- STI
1 stop28h 47m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:46 am
IAH
- STI
1 stop28h 34m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:46 am
IAH
- STI
1 stop27h 16m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:29 am
IAH
- STI
1 stop28h 43m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:29 pm
IAH
- STI
2 stops22h 33m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
HOU
- STI
2 stops12h 33m
Delta
Deal found 4/7![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:06 pm
HOU
- STI
2 stops10h 53m
Delta
Deal found 4/7![Delta logo]()
$373
Find flight deals from Houston to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 8, 2026.
Round-trip from | $381 (Kiwi.com) |
|---|---|
One-way from | $169 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $602 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sun 4/26
9:46 am-2:02 pm
1 stop27h 16m
Santiago de los Caballeros
Sat 5/2
3:07 pm-10:47 pm
1 stop8h 40m
$386
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sun 4/26
12:35 pm-2:02 pm
2 stops24h 27m
Santiago de los Caballeros
Sat 5/2
3:07 pm-10:47 pm
1 stop8h 40m
$428
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/6
8:50 pm-3:20 pm
2 stops41h 30m
Santiago de los Caballeros
Sat 5/9
3:17 pm-9:03 am
1 stop18h 46m
$453
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Mon 5/11
5:45 am-3:20 pm
1 stop8h 35m
Santiago de los Caballeros
Mon 5/18
4:15 pm-10:16 pm
3 stops31h 01m
$585
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/6
12:38 pm-12:22 am
1 stop10h 44m
Santiago de los Caballeros
Wed 5/13
8:59 pm-11:15 am
1 stop15h 16m
$610
Quickest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Tue 9/1
10:57 am-10:52 pm
1 stop10h 55m
Santiago de los Caballeros
Thu 10/1
2:07 pm-11:50 pm
1 stop10h 43m
$610
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Fri 5/8
12:39 pm-12:59 am
1 stop11h 20m
Santiago de los Caballeros
Tue 5/12
8:59 pm-11:15 am
1 stop15h 16m
$630
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Thu 5/7
6:00 am-12:59 am
2 stops17h 59m
Santiago de los Caballeros
Wed 5/20
6:00 am-10:26 pm
2 stops17h 26m
$635
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Mon 5/4
6:00 am-12:22 am
2 stops17h 22m
Santiago de los Caballeros
Mon 5/11
6:00 am-10:26 pm
2 stops17h 26m
$635
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Fri 5/8
1:06 pm-12:59 am
2 stops10h 53m
Santiago de los Caballeros
Tue 5/12
8:59 pm-12:11 pm
2 stops16h 12m
$635
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Houston to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
HO1-STI
IAH-STI
HOU-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santiago de los Caballeros
HO1-STI
IAH-STI
HOU-STI
What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $391). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston to Santiago de los Caballeros?
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated April 8, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Food
6.4
Entertainment
6.9
Comfort
7.2
Crew
7.9
Overall
7.1
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Boarding
7.5
Food
6.4
Entertainment
6.9
Comfort
7.2
Crew
7.9
Overall
7.1
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Boarding
7.5
Food
6.4
Entertainment
6.9
Comfort
7.2
Crew
7.9
Overall
7.1
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Related info for your journey
Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago de los Caballeros flight routes
Alternative routes for Houston to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santiago de los Caballeros by cabin class
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Houston and Santiago de los Caballeros flights
Browse other Houston and Santiago de los Caballeros flight options. Last updated on April 8, 2026.
Popular flight searches
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Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 8, 2026.
Top 2 airlines flying from Houston to Santiago de los Caballeros
Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$265 | Average$428 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$514 | Average$728 | FlexibilityNo cancel fee | On-time71% |