$167+ Cheap flights from Houston to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
May 1 — May 81
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Houston to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santiago de los Caballeros
Cheapest
Best
Last-minute
One-way
Cheapest flights from Houston to Santiago de los CaballerosExplore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Mon 4/132:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Mon 4/133:28 pm
STI
- IAH
1 stop18h 12m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:02 pm
IAH
- STI
1 stop12h 47m
Multiple Airlines
Mon 4/203:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:45 am
IAH
- STI
1 stop8h 35m
Multiple Airlines
Mon 6/84:15 pm
STI
- IAH
2 stops31h 33m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:53 am
HOU
- STI
2 stops12h 29m
Delta
Wed 5/68:59 pm
STI
- HOU
2 stops16h 12m
Delta
Deal found 3/30![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:27 am
HOU
- STI
2 stops13h 32m
Delta
Wed 5/208:59 pm
STI
- HOU
2 stops20h 10m
Delta
Deal found 3/30![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Fri 5/227:03 am
STI
- HOU
2 stops12h 06m
American Airlines
Deal found 3/27![American Airlines logo]()
$733
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:00 am
HOU
- STI
2 stops18h 15m
Delta
Fri 1/298:05 pm
STI
- HOU
2 stops22h 25m
Delta
Deal found 3/30![Delta logo]()
$753
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/299:05 am
HOU
- STI
2 stops9h 58m
American Airlines
Fri 1/296:02 am
STI
- HOU
2 stops12h 09m
American Airlines
Deal found 3/28![American Airlines logo]()
$765
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Sat 8/87:00 am
STI
- HOU
2 stops11h 52m
American Airlines
Deal found 3/28![American Airlines logo]()
$888
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/27![American Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
HOU
- STI
2 stops17h 47m
Delta
Mon 8/178:53 pm
STI
- HOU
2 stops20h 30m
Delta
Deal found 3/27![Delta logo]()
$967
Best flights from Houston to Santiago de los CaballerosDiscover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
Discover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:02 pm
IAH
- STI
1 stop12h 47m
Multiple Airlines
Mon 4/203:07 pm
STI
- IAH
2 stops21h 04m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$394
This Mytrip deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:15 am
IAH
- STI
2 stops19h 34m
Spirit Airlines
Mon 4/203:07 pm
STI
- IAH
3 stops18h 16m
Spirit Airlines
Deal found 3/28![Spirit Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:35 pm
IAH
- STI
1 stop16h 48m
American Airlines
Wed 5/201:32 pm
STI
- IAH
1 stop8h 57m
American Airlines
Deal found 3/27![American Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
IAH
- STI
1 stop10h 44m
Delta
Wed 5/68:59 pm
STI
- IAH
1 stop15h 16m
Delta
Deal found 3/30![Delta logo]()
$609
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:42 pm
IAH
- STI
2 stops16h 30m
Multiple Airlines
Mon 6/222:46 pm
STI
- IAH
1 stop25h 05m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:15 am
IAH
- STI
1 stop14h 58m
American Airlines
Wed 6/249:06 am
STI
- IAH
1 stop15h 53m
American Airlines
Deal found 3/29![American Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:39 pm
IAH
- STI
1 stop11h 20m
Delta
Fri 6/128:59 pm
STI
- IAH
1 stop15h 15m
Delta
Deal found 3/31![Delta logo]()
$610
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:52 am
IAH
- STI
2 stops51h 28m
Multiple Airlines
Sat 6/272:46 pm
STI
- IAH
1 stop19h 32m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:53 am
HOU
- STI
2 stops12h 29m
Delta
Wed 5/68:59 pm
STI
- HOU
2 stops16h 12m
Delta
Deal found 3/30![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:06 pm
HOU
- STI
2 stops10h 53m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/29![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:39 pm
IAH
- STI
1 stop11h 20m
Delta
Mon 6/88:59 pm
STI
- IAH
1 stop15h 15m
Delta
Deal found 3/31![Delta logo]()
$630
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:27 am
HOU
- STI
2 stops13h 32m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/27![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/27![American Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
HOU
- STI
2 stops16h 54m
Delta
Wed 4/156:00 am
STI
- HOU
2 stops18h 08m
Delta
Deal found 3/31![Delta logo]()
$1,012
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:27 pm
HOU
- STI
2 stops17h 35m
Delta
Mon 4/61:27 pm
STI
- HOU
2 stops21h 56m
Delta
Deal found 3/31![Delta logo]()
$1,075
Last-minute flights from Houston to Santiago de los CaballerosDiscover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated April 1, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated April 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
HOU
- STI
2 stops13h 29m
American Airlines
Thu 4/91:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/30![American Airlines logo]()
$1,108
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:27 pm
HOU
- STI
2 stops17h 35m
Delta
Mon 4/61:27 pm
STI
- HOU
2 stops21h 56m
Delta
Deal found 3/30![Delta logo]()
$1,058
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:02 pm
IAH
- STI
1 stop12h 47m
Multiple Airlines
Mon 4/203:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$371
This Mytrip deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:15 am
IAH
- STI
2 stops19h 34m
Spirit Airlines
Mon 4/203:07 pm
STI
- IAH
2 stops21h 04m
Spirit Airlines
Deal found 3/28![Spirit Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/27![American Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
HOU
- STI
2 stops16h 54m
Delta
Wed 4/156:00 am
STI
- HOU
2 stops18h 08m
Delta
Deal found 3/31![Delta logo]()
$1,012
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Mon 4/133:28 pm
STI
- IAH
1 stop18h 12m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
HOU
- STI
2 stops16h 54m
Delta
Mon 4/136:00 am
STI
- HOU
2 stops18h 08m
Delta
Deal found 3/30![Delta logo]()
$1,617
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Mon 4/132:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Tue 4/141:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/31![American Airlines logo]()
$1,030
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:53 am
HOU
- STI
2 stops12h 29m
Delta
Wed 5/68:59 pm
STI
- HOU
2 stops16h 12m
Delta
Deal found 3/30![Delta logo]()
$613
One-way flights from Houston to Santiago de los CaballerosSearch for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
Search for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:57 pm
IAH
- STI
2 stops42h 05m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$167
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:45 am
IAH
- STI
1 stop8h 35m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$202
This Cheapflightsfares deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
IAH
- STI
1 stop8h 35m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:45 am
IAH
- STI
2 stops31h 27m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:20 pm
IAH
- STI
2 stops24h 00m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$251
This Cheapflightsfares deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:45 am
IAH
- STI
1 stop8h 35m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:29 am
IAH
- STI
1 stop29h 51m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$271
This eDestinos deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:12 am
IAH
- STI
2 stops21h 42m
Frontier
Deal found 3/31![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:01 pm
HOU
- STI
2 stops19h 19m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:27 am
HOU
- STI
2 stops13h 32m
Delta
Deal found 3/31![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
HOU
- STI
2 stops17h 59m
Delta
Deal found 3/31![Delta logo]()
$404
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Deal found 3/31![American Airlines logo]()
$406
Find flight deals from Houston to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 1, 2026.
Round-trip from | $316 (Mytrip) |
|---|---|
One-way from | $167 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $602 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 4/4
12:02 pm-1:49 am
1 stop12h 47m
Santiago de los Caballeros
Mon 4/20
3:07 pm-11:11 am
2 stops21h 04m
$394
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 4/4
5:15 am-1:49 am
2 stops19h 34m
Santiago de los Caballeros
Mon 4/20
3:07 pm-8:23 am
3 stops18h 16m
$487
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Fri 6/12
8:42 pm-2:12 pm
2 stops16h 30m
Santiago de los Caballeros
Mon 6/22
2:46 pm-2:51 pm
1 stop25h 05m
$584
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 6/13
10:52 am-3:20 pm
2 stops51h 28m
Santiago de los Caballeros
Sat 6/27
2:46 pm-9:18 am
1 stop19h 32m
$585
Quickest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Thu 5/7
6:35 pm-12:23 pm
1 stop16h 48m
Santiago de los Caballeros
Wed 5/20
1:32 pm-9:29 pm
1 stop8h 57m
$609
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 4/29
12:38 pm-12:22 am
1 stop10h 44m
Santiago de los Caballeros
Wed 5/6
8:59 pm-11:15 am
1 stop15h 16m
$609
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Fri 6/19
5:15 am-9:13 pm
1 stop14h 58m
Santiago de los Caballeros
Wed 6/24
9:06 am-11:59 pm
1 stop15h 53m
$609
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/27
12:39 pm-12:59 am
1 stop11h 20m
Santiago de los Caballeros
Fri 6/12
8:59 pm-11:14 am
1 stop15h 15m
$610
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Wed 4/29
10:53 am-12:22 am
2 stops12h 29m
Santiago de los Caballeros
Wed 5/6
8:59 pm-12:11 pm
2 stops16h 12m
$613
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Wed 5/13
1:06 pm-12:59 am
2 stops10h 53m
Santiago de los Caballeros
Wed 5/20
6:00 am-10:26 pm
2 stops17h 26m
$613
Showing 1-10 of 31 resultsSorted by cheapest first
Best time to book a flight from Houston to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
HO1-STI
IAH-STI
HOU-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santiago de los Caballeros
HO1-STI
IAH-STI
HOU-STI
What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston to Santiago de los Caballeros?
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated April 1, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Crew
7.9
Food
6.4
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Overall
7.1
Crew
7.9
Food
6.4
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Overall
7.1
Crew
7.9
Food
6.4
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Related info for your journey
Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Santiago de los Caballeros flight routes
Alternative routes for Houston to Santiago de los Caballeros
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santiago de los Caballeros by cabin class
Find flights from Houston to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Santiago de los Caballeros flights
Browse other Houston and Santiago de los Caballeros flight options. Last updated on April 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 1, 2026.
Top 2 airlines flying from Houston to Santiago de los Caballeros
Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$265 | Average$424 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$514 | Average$753 | FlexibilityNo cancel fee | On-time71% |