$168+ Cheap flights from Houston to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — STI
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santiago de los Caballeros
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Cheapest flights from Houston to Santiago de los CaballerosExplore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Houston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Sun 4/52:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Tue 4/73:28 pm
STI
- IAH
1 stop18h 12m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$371
This CheapOair deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Thu 4/92:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$372
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Tue 4/72:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$390
This Trip.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Mon 4/132:46 am
STI
- IAH
2 stops20h 50m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Sun 4/193:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:10 am
IAH
- STI
2 stops18h 39m
Multiple Airlines
Tue 4/72:46 am
STI
- IAH
1 stop15h 46m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:26 am
IAH
- STI
1 stop15h 23m
Multiple Airlines
Sat 4/183:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$415
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Wed 5/201:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/11![American Airlines logo]()
$593
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
HOU
- STI
2 stops17h 22m
Delta
Wed 5/66:00 am
STI
- HOU
2 stops11h 28m
Delta
Deal found 3/15![Delta logo]()
$613
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Sun 5/101:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/11![American Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:53 am
HOU
- STI
2 stops12h 29m
Delta
Tue 4/216:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 3/12![Delta logo]()
$623
Best flights from Houston to Santiago de los CaballerosDiscover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Houston to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This CheapOair deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Thu 4/92:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:19 pm
HOU
- STI
2 stops19h 04m
American Airlines
Wed 5/201:32 pm
STI
- HOU
2 stops11h 15m
American Airlines
Deal found 3/11![American Airlines logo]()
$593
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:38 pm
IAH
- STI
1 stop10h 44m
Delta
Wed 5/206:00 am
STI
- IAH
2 stops16h 25m
Delta
Deal found 3/14![Delta logo]()
$613
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Tue 4/72:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:35 pm
IAH
- STI
2 stops24h 27m
Spirit Airlines
Mon 5/43:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 3/11![Spirit Airlines logo]()
$473
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:15 am
IAH
- STI
3 stops19h 34m
Spirit Airlines
Mon 4/132:46 am
STI
- IAH
3 stops20h 50m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$512
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:53 am
HOU
- STI
2 stops12h 29m
Delta
Tue 4/216:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 3/12![Delta logo]()
$623
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:19 am
IAH
- STI
1 stop8h 56m
American Airlines
Fri 7/107:03 am
STI
- IAH
1 stop17h 56m
American Airlines
Deal found 3/11![American Airlines logo]()
$677
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:48 am
HOU
- STI
2 stops12h 34m
Delta
Tue 5/56:00 am
STI
- HOU
2 stops11h 28m
Delta
Deal found 3/14![Delta logo]()
$633
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/11![American Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:24 am
IAH
- STI
2 stops17h 58m
Delta
Tue 5/58:59 pm
STI
- IAH
1 stop15h 36m
Delta
Deal found 3/14![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:35 pm
IAH
- STI
2 stops16h 48m
Delta
Wed 7/156:15 am
STI
- IAH
2 stops16h 44m
Delta
Deal found 3/11![Delta logo]()
$653
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Tue 4/141:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/12![American Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
HOU
- STI
2 stops17h 59m
Delta
Wed 5/206:00 am
STI
- HOU
2 stops17h 26m
Delta
Deal found 3/14![Delta logo]()
$693
Last-minute flights from Houston to Santiago de los CaballerosDiscover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santiago de los Caballeros. Data last updated March 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:26 am
IAH
- STI
1 stop15h 23m
Multiple Airlines
Sat 4/183:07 pm
STI
- IAH
1 stop21h 20m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$415
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Tue 4/72:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:10 am
IAH
- STI
2 stops18h 39m
Multiple Airlines
Tue 4/72:46 am
STI
- IAH
1 stop15h 46m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$401
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Sun 4/52:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Sun 4/53:28 pm
STI
- IAH
1 stop18h 12m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$371
This CheapOair deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:22 pm
IAH
- STI
1 stop8h 27m
Spirit Airlines
Thu 4/92:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:30 pm
IAH
- STI
2 stops8h 19m
Spirit Airlines
Mon 4/62:46 am
STI
- IAH
1 stop6h 54m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$399
This Trip.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Mon 4/132:46 am
STI
- IAH
2 stops20h 50m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Wed 4/151:32 pm
STI
- HOU
2 stops20h 54m
American Airlines
Deal found 3/11![American Airlines logo]()
$693
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Sun 4/193:07 pm
STI
- IAH
1 stop21h 20m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:53 am
HOU
- STI
2 stops12h 29m
Delta
Tue 4/216:00 am
STI
- HOU
2 stops18h 07m
Delta
Deal found 3/12![Delta logo]()
$623
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
HOU
- STI
2 stops17h 22m
Delta
Wed 5/66:00 am
STI
- HOU
2 stops11h 28m
Delta
Deal found 3/15![Delta logo]()
$613
One-way flights from Houston to Santiago de los CaballerosSearch for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Houston to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This Trip.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:26 am
IAH
- STI
1 stop15h 23m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$170
This Mytrip deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
IAH
- STI
1 stop7h 38m
Spirit Airlines
Deal found 3/15![Spirit Airlines logo]()
$171
This Mytrip deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/284:30 pm
IAH
- STI
2 stops20h 53m
Spirit Airlines
Deal found 3/10![Spirit Airlines logo]()
$200
This Trip.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:26 am
IAH
- STI
1 stop15h 23m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$212
This Cheapflightsfares deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:35 am
IAH
- STI
1 stop17h 14m
Spirit Airlines
Deal found 3/12![Spirit Airlines logo]()
$230
This Cheapflightsfares deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
IAH
- STI
1 stop7h 02m
Spirit Airlines
Deal found 3/13![Spirit Airlines logo]()
$270
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:50 am
IAH
- STI
1 stop9h 59m
JetBlue
Deal found 3/15![JetBlue logo]()
$313
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
HOU
- STI
2 stops17h 22m
Delta
Deal found 3/15![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:03 am
HOU
- STI
2 stops14h 10m
American Airlines
Deal found 3/15![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:20 pm
HOU
- STI
2 stops15h 10m
American Airlines
Deal found 3/12![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:18 pm
HOU
- STI
2 stops19h 05m
American Airlines
Deal found 3/15![American Airlines logo]()
$448
Find flight deals from Houston to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.
Round-trip from | $368 (Mytrip) |
|---|---|
One-way from | $168 (Trip.com) |
Popular in | August |
Cheapest in | October |
Average price | $573 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Fri 4/3
4:22 pm-1:49 am
1 stop8h 27m
Santiago de los Caballeros
Thu 4/9
2:46 am-8:40 am
1 stop6h 54m
$372
Quickest round-trip
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 4/1
5:45 am-2:23 pm
1 stop7h 38m
Santiago de los Caballeros
Tue 4/7
2:46 am-8:40 am
1 stop6h 54m
$390
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 5/2
12:35 pm-2:02 pm
2 stops24h 27m
Santiago de los Caballeros
Mon 5/4
3:07 pm-11:27 am
1 stop21h 20m
$473
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Tue 4/7
5:15 am-1:49 am
3 stops19h 34m
Santiago de los Caballeros
Mon 4/13
2:46 am-10:36 pm
3 stops20h 50m
$512
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Thu 5/7
4:19 pm-12:23 pm
2 stops19h 04m
Santiago de los Caballeros
Wed 5/20
1:32 pm-11:47 pm
2 stops11h 15m
$593
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Wed 5/6
12:38 pm-12:22 am
1 stop10h 44m
Santiago de los Caballeros
Wed 5/20
6:00 am-9:25 pm
2 stops16h 25m
$613
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Thu 4/16
10:53 am-12:22 am
2 stops12h 29m
Santiago de los Caballeros
Tue 4/21
6:00 am-11:07 pm
2 stops18h 07m
$623
HoustonSantiago de los Caballeros
HOU - STI
HOUSTI
Houston Hobby
Sat 5/2
10:48 am-12:22 am
2 stops12h 34m
Santiago de los Caballeros
Tue 5/5
6:00 am-4:28 pm
2 stops11h 28m
$633
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Sat 5/2
5:24 am-12:22 am
2 stops17h 58m
Santiago de los Caballeros
Tue 5/5
8:59 pm-11:35 am
1 stop15h 36m
$633
HoustonSantiago de los Caballeros
IAH - STI
IAHSTI
Houston George Bush Intcntl
Mon 6/1
6:35 pm-12:23 pm
2 stops16h 48m
Santiago de los Caballeros
Wed 7/15
6:15 am-9:59 pm
2 stops16h 44m
$653
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Houston to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Houston with our price prediction graph.
HO1-STI
IAH-STI
HOU-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santiago de los Caballeros
HO1-STI
IAH-STI
HOU-STI
What is the cheapest month to book a flight from Houston to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Houston to Santiago de los Caballeros (average of $112). Flying from Houston to Santiago de los Caballeros in June is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated March 15, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Houston to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Overall
7.1
Comfort
7.2
Entertainment
6.9
Boarding
7.5
Food
6.4
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Crew
7.9
Overall
7.1
Comfort
7.2
Entertainment
6.9
Boarding
7.5
Food
6.4
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Crew
7.9
Overall
7.1
Comfort
7.2
Entertainment
6.9
Boarding
7.5
Food
6.4
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Related info for your journey
Find useful and relevant information for your journey from Houston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago de los Caballeros flight routes
Alternative routes for Houston to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santiago de los Caballeros by cabin class
Find flights from Houston to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Santiago de los Caballeros flights
Browse other Houston and Santiago de los Caballeros flight options. Last updated on March 15, 2026.
Popular flight searches
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Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Top 2 airlines flying from Houston to Santiago de los Caballeros
Discover the top 2 airlines that operate flights from Houston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$265 | Average$426 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$514 | Average$768 | FlexibilityNo cancel fee | On-time71% |