$356+ Cheap flights from Detroit (DTT) to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — STI
Sep 2 — Sep 91
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Santiago de los Caballeros
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Cheapest flights from Detroit to Santiago de los CaballerosExplore the most affordable flight options available from Detroit to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
Explore the most affordable flight options available from Detroit to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 3, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Sat 12/56:01 am
STI
- DTW
1 stop10h 08m
JetBlue
Deal found 7/30![JetBlue logo]()
$425
This JetBlue deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Thu 9/173:30 pm
STI
- DTW
1 stop7h 53m
JetBlue
Deal found 7/30![JetBlue logo]()
$428
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Sat 9/263:30 pm
STI
- DTW
1 stop7h 53m
JetBlue
Deal found 7/30![JetBlue logo]()
$459
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:05 pm
DTW
- STI
1 stop7h 52m
JetBlue
Sun 12/66:01 am
STI
- DTW
1 stop10h 08m
JetBlue
Deal found 7/30![JetBlue logo]()
$493
This Faresmojo deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Wed 9/303:30 pm
STI
- DTW
1 stop7h 53m
JetBlue
Deal found 8/2![JetBlue logo]()
$516
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am
DTW
- STI
1 stop8h 15m
American Airlines
Mon 10/192:18 pm
STI
- DTW
1 stop9h 36m
American Airlines
Deal found 7/31![American Airlines logo]()
$780
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:37 pm
DTW
- STI
2 stops18h 38m
American Airlines
Sat 12/57:00 am
STI
- DTW
2 stops13h 10m
American Airlines
Deal found 7/30![American Airlines logo]()
$795
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
DTW
- STI
1 stop8h 15m
American Airlines
Wed 9/303:15 pm
STI
- DTW
1 stop7h 42m
American Airlines
Deal found 8/1![American Airlines logo]()
$809
Best flights from Detroit to Santiago de los CaballerosDiscover carefully curated flight deals from Detroit to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
Discover carefully curated flight deals from Detroit to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 3, 2026.
This Faresmojo deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Wed 9/303:49 pm
STI
- DTW
1 stop7h 41m
JetBlue
Deal found 8/3![JetBlue logo]()
$516
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:10 pm
DTW
- STI
2 stops21h 05m
American Airlines
Wed 9/303:15 pm
STI
- DTW
1 stop7h 42m
American Airlines
Deal found 8/3![American Airlines logo]()
$812
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am
DTW
- STI
1 stop8h 12m
United Airlines
Sun 9/66:00 am
STI
- DTW
2 stops11h 00m
United Airlines
Deal found 7/31![United Airlines logo]()
$875
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am
DTW
- STI
1 stop8h 32m
American Airlines
Sun 12/67:00 am
STI
- DTW
2 stops13h 10m
American Airlines
Deal found 7/30![American Airlines logo]()
$845
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:30 am
DTW
- STI
2 stops15h 22m
United Airlines
Wed 10/216:00 am
STI
- DTW
2 stops16h 15m
United Airlines
Deal found 8/2![United Airlines logo]()
$995
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am
DTW
- STI
1 stop8h 15m
American Airlines
Mon 9/213:15 pm
STI
- DTW
1 stop7h 42m
American Airlines
Deal found 8/2![American Airlines logo]()
$945
Last-minute flights from Detroit to Santiago de los CaballerosDiscover last-minute flight deals from Detroit to Santiago de los Caballeros. Data last updated August 3, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Santiago de los Caballeros. Data last updated August 3, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Thu 9/173:30 pm
STI
- DTW
1 stop7h 53m
JetBlue
Deal found 7/30![JetBlue logo]()
$428
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Sat 12/56:01 am
STI
- DTW
1 stop10h 08m
JetBlue
Deal found 7/30![JetBlue logo]()
$425
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:37 pm
DTW
- STI
2 stops18h 38m
American Airlines
Sat 12/57:00 am
STI
- DTW
2 stops13h 10m
American Airlines
Deal found 7/30![American Airlines logo]()
$795
This Faresmojo deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Wed 9/303:30 pm
STI
- DTW
1 stop7h 53m
JetBlue
Deal found 8/2![JetBlue logo]()
$516
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
DTW
- STI
1 stop8h 15m
American Airlines
Wed 9/303:15 pm
STI
- DTW
1 stop7h 42m
American Airlines
Deal found 8/1![American Airlines logo]()
$809
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Sat 9/263:30 pm
STI
- DTW
1 stop7h 53m
JetBlue
Deal found 7/30![JetBlue logo]()
$459
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am
DTW
- STI
1 stop8h 15m
American Airlines
Mon 10/192:18 pm
STI
- DTW
1 stop9h 36m
American Airlines
Deal found 7/31![American Airlines logo]()
$780
One-way flights from Detroit to Santiago de los CaballerosSearch for one-way flight options from Detroit to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
Search for one-way flight options from Detroit to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated August 3, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am
DTW
- STI
1 stop6h 27m
JetBlue
Deal found 7/31![JetBlue logo]()
$356
This Faresmojo deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am
DTW
- STI
1 stop17h 57m
JetBlue
Deal found 8/3![JetBlue logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:23 pm
DTW
- STI
2 stops41h 07m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:07 am
DTW
- STI
2 stops8h 26m
American Airlines
Deal found 8/2![American Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:10 am
DTW
- STI
2 stops9h 53m
American Airlines
Deal found 8/2![American Airlines logo]()
$513
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am
DTW
- STI
1 stop16h 51m
United Airlines
Deal found 8/2![United Airlines logo]()
$561
This Faresmojo deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2310:15 am
DTW
- STI
1 stop15h 00m
JetBlue
Deal found 8/2![JetBlue logo]()
$603
Find flight deals from Detroit to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $425 (Cheapflightsfares) |
One-way from | $356 (Cheapflightsfares) |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
Use the filters below to find and compare flights from Detroit to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Wed 9/16
7:00 am-1:27 pm
1 stop6h 27m
Santiago de los Caballeros
Wed 9/30
3:49 pm-11:30 pm
1 stop7h 41m
$516
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Wed 9/16
5:10 pm-2:15 pm
2 stops21h 05m
Santiago de los Caballeros
Wed 9/30
3:15 pm-10:57 pm
1 stop7h 42m
$812
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Thu 12/3
6:00 am-3:32 pm
1 stop8h 32m
Santiago de los Caballeros
Sun 12/6
7:00 am-7:10 pm
2 stops13h 10m
$845
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Sun 8/30
7:00 am-3:12 pm
1 stop8h 12m
Santiago de los Caballeros
Sun 9/6
6:00 am-5:00 pm
2 stops11h 00m
$875
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Tue 9/15
6:00 am-2:15 pm
1 stop8h 15m
Santiago de los Caballeros
Mon 9/21
3:15 pm-10:57 pm
1 stop7h 42m
$945
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Mon 10/19
7:30 am-10:52 pm
2 stops15h 22m
Santiago de los Caballeros
Wed 10/21
6:00 am-10:15 pm
2 stops16h 15m
$995
Cheapest one-way
Quickest one-way
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Sat 9/19
7:00 am-1:27 pm
1 stop6h 27m
$356
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Sat 9/19
4:23 pm-9:30 am
2 stops41h 07m
$418
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Fri 12/11
11:07 am-8:33 pm
2 stops8h 26m
$471
DetroitSantiago de los Caballeros
DTW - STI
DTWSTI
Detroit Metropolitan Wayne County
Thu 12/24
10:10 am-9:03 pm
2 stops9h 53m
$521
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Detroit to Santiago de los Caballeros
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santiago de los Caballeros in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Santiago de los Caballeros flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Detroit with our price prediction graph.
DTT-STI
DTW-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Santiago de los Caballeros
DTT-STI
DTW-STI
What is the cheapest month to book a flight from Detroit to Santiago de los Caballeros?
Currently, August is the cheapest month in which you can book a flight from Detroit to Santiago de los Caballeros (average of $367). Flying from Detroit to Santiago de los Caballeros in June is currently the most expensive (average of $864). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Detroit to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Popular flights
Santiago de los Caballeros flight routes
Alternative routes for Detroit to Santiago de los Caballeros
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Santiago de los Caballeros by cabin class
Find flights from Detroit to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Santiago de los Caballeros flights
Browse other Detroit and Santiago de los Caballeros flight options. Last updated on August 3, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on August 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 3, 2026.
Top airline flying from Detroit to Santiago de los Caballeros
Discover the top airline that operate flights from Detroit to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$442 | Average$669 | FlexibilityNo cancel fee | On-time62% |