
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $257 (LATAM Airlines) |
One-way from | $121 (JetSMART) |
Popular in | July |
Cheapest in | November |
Average price | $282 |
Good round-trip deal | $278 or less |
Good one-way deal | $151 or less |
Fly from
Fly to
Route
Depart
Return
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Thu 8/13
5:05 am-8:30 am
Nonstop4h 25m
Santiago Arturo Merino Benitez
Mon 8/17
10:15 am-3:00 pm
Nonstop3h 45m
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Fri 9/4
8:20 pm-8:25 am
1 stop13h 05m
Santiago Arturo Merino Benitez
Mon 9/7
8:50 pm-9:05 am
1 stop12h 15m
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Fri 11/13
10:45 pm-1:45 pm
3 stops39h 00m
Santiago Arturo Merino Benitez
Mon 11/23
8:50 pm-9:05 am
1 stop12h 15m
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Thu 8/6
10:35 pm-8:25 am
2 stops34h 50m
Santiago Arturo Merino Benitez
Thu 8/13
8:50 pm-11:05 am
1 stop13h 15m
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Mon 9/7
10:00 pm-5:05 pm
2 stops43h 05m
Santiago Arturo Merino Benitez
Mon 9/21
8:50 pm-9:05 am
1 stop12h 15m
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Fri 11/20
10:10 pm-8:00 pm
2 stops21h 50m
Santiago Arturo Merino Benitez
Sun 11/22
2:35 pm-10:25 pm
1 stop7h 50m
Sao PauloSantiago
VCP - SCL
VCPSCL
Sao Paulo Viracopos
Wed 8/5
10:25 am-7:35 pm
2 stops34h 10m
Santiago Arturo Merino Benitez
Wed 8/12
8:50 pm-10:55 pm
2 stops25h 05m
Sao PauloSantiago
CGH - SCL
CGHSCL
Sao Paulo Congonhas
Fri 11/6
6:40 am-5:05 pm
2 stops10h 25m
Santiago Arturo Merino Benitez
Sun 11/15
9:15 am-7:20 am
2 stops22h 05m
Sao PauloSantiago
GRU - SCL
GRUSCL
Sao Paulo Guarulhos Intl
Mon 8/3
10:00 pm-7:35 pm
2 stops22h 35m
Santiago Arturo Merino Benitez
Fri 8/7
8:50 pm-11:05 am
1 stop13h 15m
Sao PauloSantiago
VCP - SCL
VCPSCL
Sao Paulo Viracopos
Fri 11/6
7:40 pm-8:00 pm
2 stops24h 20m
Santiago Arturo Merino Benitez
Sun 11/15
9:15 am-10:00 am
2 stops24h 45m
Currently, March is the cheapest month in which you can book a flight from Sao Paulo to Santiago (average of $237). Flying from Sao Paulo to Santiago in April is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
When flying from Sao Paulo to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 29% versus a flight at noon.
The most flights from SAO to SCL are scheduled on a Tuesday (27 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (8 on average).
About 22% of weekly flights between Sao Paulo and Santiago have experienced delays in the past year, with the average delay time being 124 minutes.
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
Thursday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 21% of flights being delayed.
To ensure you get the cheapest price possible for a flight from Sao Paulo to Santiago, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Travelers seeking maximum savings on their Sao Paulo to Santiago flight should consider departing on Saturday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Overall
Boarding
Entertainment
Comfort
Food
Crew
Reviews
Victoria E,Mar 2026
SCL - JFK
Overall
Boarding
Entertainment
Comfort
Food
Crew
Reviews
Victoria E,Mar 2026
SCL - JFK
Overall
Boarding
Entertainment
Comfort
Food
Crew
Reviews
Victoria E,Mar 2026
SCL - JFK
Overall
Boarding
Entertainment
Comfort
Food
Crew
Reviews
Victoria E,Mar 2026
SCL - JFK
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$138 | Average$224 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$164 | Average$247 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$220 | Average$237 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$243 | Average$357 | FlexibilityNo cancel fee | On-time81% |