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$633+ Cheap flights from Santa Fe (SAF) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — SCL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Santa Fe to Santiago

Cheapest flights from Santa Fe to Santiago
Explore the most affordable flight options available from Santa Fe to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:20 pmSAF - SCL
2 stops15h 30mUnited Airlines
Wed 12/1010:45 pmSCL - SAF
2 stops19h 54mUnited Airlines
Deal found 10/27$809
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:15 amSAF - SCL
1 stop21h 30mAmerican Airlines
Wed 12/1011:15 pmSCL - SAF
1 stop21h 06mAmerican Airlines
Deal found 10/27$960

Cheap flight deals from Santa Fe to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Round-trip from

$809
(United Airlines)

One-way from

$633
(United Airlines)
From Santa Fe to Santiago Arturo Merino Benitez
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One-way flight from Santa Fe to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Santa Fe to Santiago that are best for you.

Fly from

Santa Fe

Fly to

Santiago

Route

Depart

Return

Price

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 12/6

1:20 pm-8:50 am

2 stops15h 30m

Santiago Arturo Merino Benitez

Wed 12/10

10:45 pm-12:37 pm

2 stops17h 52m

$809

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 1/31

6:05 pm-8:50 am

2 stops58h 45m

Santiago Arturo Merino Benitez

Sat 2/14

10:45 pm-5:08 pm

2 stops22h 23m

$874

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 1/31

10:28 am-9:00 am

2 stops18h 32m

Santiago Arturo Merino Benitez

Sat 2/14

11:15 pm-9:38 am

1 stop14h 23m

$894

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 12/6

9:58 am-7:45 am

1 stop17h 47m

Santiago Arturo Merino Benitez

Wed 12/10

11:15 pm-9:28 am

1 stop14h 13m

$960

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 11/15

7:00 am-8:50 am

2 stops21h 50m

$633

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Best time to book a flight from Santa Fe to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Santiago

What is the cheapest month to book a flight from Santa Fe to Santiago?

Currently, November is the cheapest month in which you can book a flight from Santa Fe to Santiago (average of $803). Flying from Santa Fe to Santiago in August is currently the most expensive (average of $953). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to Santiago?

    Departing from Santa Fe to Santiago will take you 15h 30m. Santa Fe and Santiago are separated by a distance of 5282 mi.

  • Can I find deals for flights from Santa Fe to Santiago that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Santiago.

  • Can I find deals for business class flights from Santa Fe to Santiago?

    Yes. Cheapflights offers flight deals from Santa Fe to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Santa Fe to Santiago (average of $803). Flying from Santa Fe to Santiago in August is currently the most expensive (average of $953). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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