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$446+ Cheap flights from San Pedro Sula (SAP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAP — SCL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from San Pedro Sula to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Pedro Sula (SAP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$684
(Mytrip)

One-way from

$446
(Avianca)

Popular in

October

Cheapest in

April

Average price

$666
From San Pedro Sula Ramon Villeda to Santiago Arturo Merino Benitez
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One-way flight from San Pedro Sula Ramon Villeda to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 1% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Pedro Sula to Santiago

Cheapest flights from San Pedro Sula to Santiago
Explore the most affordable flight options available from San Pedro Sula to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1110:47 amSAP - SCL
3 stops32h 28mMultiple Airlines
Sat 11/155:50 amSCL - SAP
2 stops35h 20mMultiple Airlines
Deal found 9/14$684
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/164:30 amSAP - SCL
3 stops29h 50mMultiple Airlines
Sun 10/1912:30 pmSCL - SAP
2 stops27h 35mMultiple Airlines
Deal found 9/15$742
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/84:30 amSAP - SCL
2 stops16h 00mAvianca
Wed 10/227:10 amSCL - SAP
3 stops19h 10mAvianca
Deal found 9/14$841

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Pedro Sula to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from San Pedro Sula to Santiago that are best for you.

Fly from

San Pedro Sula

Fly to

Santiago

Route

Depart

Return

Price

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Thu 10/16

4:30 am-1:20 pm

3 stops29h 50m

Santiago Arturo Merino Benitez

Sun 10/19

12:30 pm-1:05 pm

2 stops27h 35m

$742

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Mon 11/10

1:53 am-5:20 pm

3 stops36h 27m

Santiago Arturo Merino Benitez

Sat 11/15

12:30 pm-2:10 pm

2 stops28h 40m

$755

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 10/8

4:30 am-11:30 pm

2 stops16h 00m

Santiago Arturo Merino Benitez

Wed 10/22

7:10 am-11:20 pm

3 stops19h 10m

$841

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Thu 10/23

8:10 pm-2:25 pm

2 stops15h 15m

Santiago Arturo Merino Benitez

Sat 10/25

9:05 pm-12:00 pm

3 stops41h 55m

$893

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Sat 11/8

1:53 pm-3:43 am

1 stop10h 50m

Santiago Arturo Merino Benitez

Fri 11/14

3:23 am-12:48 pm

1 stop12h 25m

$939

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Tue 10/14

1:49 pm-6:00 am

1 stop13h 11m

Santiago Arturo Merino Benitez

Tue 10/21

4:47 am-12:45 pm

1 stop10h 58m

$939

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 10/8

1:49 pm-6:00 am

1 stop13h 11m

Santiago Arturo Merino Benitez

Tue 10/21

1:13 am-12:45 pm

1 stop14h 32m

$939

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 10/8

4:30 am-11:30 pm

2 stops16h 00m

$446

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 11/14

1:53 pm-3:43 am

1 stop10h 50m

$481

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 10/8

1:49 pm-3:42 am

1 stop10h 53m

$481

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 12 results
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Best time to book a flight from San Pedro Sula to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Pedro Sula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Pedro Sula to Santiago

How far ahead should I book a flight from San Pedro Sula to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Pedro Sula to Santiago. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from San Pedro Sula to Santiago, you should look to book at least 15 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Pedro Sula to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Pedro Sula to Santiago (average of $752). Flying from San Pedro Sula to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAP to SCL?

Find hourly flight availability from San Pedro Sula to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

It’s typically best to fly out from San Pedro Sula to Santiago in the afternoon. Doing so could potentially save you 7% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from San Pedro Sula to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from San Pedro Sula to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Pedro Sula to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Pedro Sula to Santiago?

    Departing from San Pedro Sula to Santiago will take you 16h. The distance from San Pedro Sula to Santiago is about 3557 mi.

  • What are the cheapest airlines flying from San Pedro Sula to Santiago round-trip?

    According to our current data, Avianca ($472), and Copa Airlines ($579) offers the cheapest pricing from San Pedro Sula to Santiago. Avianca is 36% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from San Pedro Sula to Santiago that include hotel bookings?

    Yes. In addition to deals on San Pedro Sula to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Pedro Sula to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Pedro Sula to Santiago.

  • Can I find deals for business class flights from San Pedro Sula to Santiago?

    Yes. Cheapflights offers flight deals from San Pedro Sula to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Pedro Sula to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Pedro Sula to Santiago (average of $752). Flying from San Pedro Sula to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Top 2 airlines flying from San Pedro Sula to Santiago

Discover the top 2 airlines that operate flights from San Pedro Sula to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$472Average$655FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$579Average$878FlexibilityNo cancel feeOn-time70%

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