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$532+ Cheap flights from San Pedro Sula (SAP) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAP — SCL
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from San Pedro Sula to Santiago

Cheapest flights from San Pedro Sula to Santiago
Explore the most affordable flight options available from San Pedro Sula to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Copa Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:07 am
SAP
-
SCL
1 stop20h 13m
Copa Airlines
Thu 4/3012:38 am
SCL
-
SAP
1 stop14h 09m
Copa Airlines
Deal found 2/4$532
This FlightHub deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:30 am
SAP
-
SCL
2 stops31h 45m
Avianca
Thu 4/3012:30 am
SCL
-
SAP
2 stops20h 15m
Avianca
Deal found 2/4$624
This Copa Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:46 pm
SAP
-
SCL
1 stop10h 34m
Copa Airlines
Sun 8/3011:22 am
SCL
-
SAP
1 stop14h 10m
Copa Airlines
Deal found 2/4$647
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/171:46 pm
SAP
-
SCL
1 stop10h 34m
Copa Airlines
Tue 6/2311:17 am
SCL
-
SAP
1 stop14h 15m
Copa Airlines
Deal found 2/2$664
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:31 am
SAP
-
SCL
1 stop16h 18m
Copa Airlines
Fri 3/135:44 am
SCL
-
SAP
1 stop20h 45m
Copa Airlines
Deal found 2/3$674
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:31 am
SAP
-
SCL
1 stop16h 18m
Copa Airlines
Wed 4/13:30 am
SCL
-
SAP
1 stop12h 17m
Copa Airlines
Deal found 2/3$919
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:07 am
SAP
-
SCL
1 stop13h 16m
Multiple Airlines
Fri 5/111:17 am
SCL
-
SAP
2 stops14h 08m
Multiple Airlines
Deal found 2/2$963
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:07 am
SAP
-
SCL
1 stop17h 19m
Copa Airlines
Wed 4/84:17 am
SCL
-
SAP
1 stop10h 30m
Copa Airlines
Deal found 2/2$987
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/291:44 pm
SAP
-
SCL
1 stop11h 14m
Copa Airlines
Fri 4/35:49 am
SCL
-
SAP
1 stop9h 58m
Copa Airlines
Deal found 2/2$1,033

Find flight deals from San Pedro Sula to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Pedro Sula (SAP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$532
(Copa Airlines)

Popular in

November

Cheapest in

April

Average price

$887
Provider with most accurate pricing for San Pedro Sula Ramon Villeda-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Pedro Sula Ramon Villeda-Santiago Arturo Merino Benitez flights.
Search Deals
From San Pedro Sula Ramon Villeda to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Pedro Sula to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from San Pedro Sula to Santiago that are best for you.

Fly from

San Pedro Sula

Fly to

Santiago

Route

Depart

Return

Price

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Sun 4/12

1:49 pm-3:00 am

1 stop11h 11m

Santiago Arturo Merino Benitez

Sat 4/18

2:30 am-12:47 pm

1 stop12h 17m

$532

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 4/24

4:07 am-7:23 pm

1 stop13h 16m

Santiago Arturo Merino Benitez

Thu 4/30

12:01 am-12:47 pm

1 stop14h 46m

$532

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Thu 4/16

1:49 pm-3:00 am

1 stop11h 11m

Santiago Arturo Merino Benitez

Wed 4/22

12:09 am-12:47 pm

1 stop14h 38m

$532

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Tue 4/21

1:49 pm-2:20 am

1 stop10h 31m

Santiago Arturo Merino Benitez

Thu 4/30

4:17 am-12:47 pm

1 stop10h 30m

$532

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Sat 3/14

4:31 am-8:20 pm

1 stop12h 49m

Santiago Arturo Merino Benitez

Tue 3/31

1:46 am-12:47 pm

1 stop14h 01m

$532

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 4/24

4:30 am-11:20 pm

2 stops16h 50m

Santiago Arturo Merino Benitez

Thu 4/30

12:30 am-6:45 pm

2 stops20h 15m

$624

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Mon 2/23

1:55 pm-7:25 pm

3 stops50h 30m

$617

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Tue 2/17

2:47 pm-3:35 am

3 stops57h 48m

$641

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Sun 2/22

2:47 pm-5:14 am

2 stops35h 27m

$647

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Tue 2/24

2:47 pm-3:35 am

3 stops57h 48m

$669

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 12 results
1
2
  • Most accurate provider: When it comes to deals on San Pedro Sula-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Pedro Sula-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Pedro Sula-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Pedro Sula-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Pedro Sula-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Pedro Sula to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Pedro Sula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Pedro Sula to Santiago

How far ahead should I book a flight from San Pedro Sula to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Pedro Sula to Santiago. Price data was last updated on January 30, 2026.

To ensure you get the cheapest price possible for a flight from San Pedro Sula to Santiago, you should look to book at least 15 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Pedro Sula to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Pedro Sula to Santiago (average of $279). Flying from San Pedro Sula to Santiago in December is currently the most expensive (average of $616). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated February 4, 2026.
Read reviews from past customers who have flown Copa Airlines and Avianca from San Pedro Sula to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,556 reviews

Comfort

7.4

Overall

7.5

Boarding

7.8

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.5
Good
1,556 reviews
Copa Airlines
7.5
Good
1,556 reviews

Comfort

7.4

Overall

7.5

Boarding

7.8

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.5
Okay
2,499 reviews
Copa Airlines
7.5
Good
1,556 reviews

Comfort

7.4

Overall

7.5

Boarding

7.8

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from San Pedro Sula to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Pedro Sula to Santiago?

    Departing from San Pedro Sula to Santiago will take you 11h 11m. The distance from San Pedro Sula to Santiago is about 3557 mi.

  • What are the cheapest airlines flying from San Pedro Sula to Santiago round-trip?

    According to our current data, Avianca ($451), and Copa Airlines ($651) offers the cheapest pricing from San Pedro Sula to Santiago. Avianca is 38% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from San Pedro Sula to Santiago that include hotel bookings?

    Yes. In addition to deals on San Pedro Sula to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Pedro Sula to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Pedro Sula to Santiago.

  • Can I find deals for business class flights from San Pedro Sula to Santiago?

    Yes. Cheapflights offers flight deals from San Pedro Sula to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Pedro Sula to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Pedro Sula to Santiago (average of $279). Flying from San Pedro Sula to Santiago in December is currently the most expensive (average of $616). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top 2 airlines flying from San Pedro Sula to Santiago

Discover the top 2 airlines that operate flights from San Pedro Sula to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$451Average$674FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$651Average$882FlexibilityNo cancel feeOn-time70%

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