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$334+ Cheap flights from San Pedro Sula (SAP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAP — SCL
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from San Pedro Sula to Santiago

Cheapest flights from San Pedro Sula to Santiago
Explore the most affordable flight options available from San Pedro Sula to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/291:53 pmSAP - SCL
1 stop10h 50mCopa Airlines
Tue 1/65:20 amSCL - SAP
1 stop10h 20mCopa Airlines
Deal found 12/16$640
This FlightHub deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:20 amSAP - SCL
2 stops32h 00mAvianca
Fri 12/267:25 amSCL - SAP
2 stops28h 05mAvianca
Deal found 12/17$1,335
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:26 amSAP - SCL
1 stop20h 17mCopa Airlines
Fri 12/2612:20 pmSCL - SAP
1 stop14h 13mCopa Airlines
Deal found 12/15$1,416
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:26 amSAP - SCL
1 stop12h 55mCopa Airlines
Sat 2/141:46 amSCL - SAP
1 stop13h 59mCopa Airlines
Deal found 12/17$1,451
This FlightHub deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:25 amSAP - SCL
2 stops15h 18mMultiple Airlines
Fri 12/2612:20 pmSCL - SAP
1 stop14h 13mMultiple Airlines
Deal found 12/17$1,468
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:53 pmSAP - SCL
1 stop13h 08mCopa Airlines
Wed 12/245:44 amSCL - SAP
1 stop10h 04mCopa Airlines
Deal found 12/16$1,474
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:53 pmSAP - SCL
1 stop10h 50mCopa Airlines
Wed 12/243:23 amSCL - SAP
1 stop12h 25mCopa Airlines
Deal found 12/17$1,508
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:15 amSAP - SCL
2 stops29h 35mUnited Airlines
Tue 1/610:45 pmSCL - SAP
1 stop16h 50mUnited Airlines
Deal found 12/17$2,432
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:15 amSAP - SCL
2 stops29h 35mUnited Airlines
Sun 2/1510:45 pmSCL - SAP
1 stop16h 50mUnited Airlines
Deal found 12/16$2,487
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2812:15 amSAP - SCL
2 stops29h 35mUnited Airlines
Tue 1/610:45 pmSCL - SAP
1 stop16h 50mUnited Airlines
Deal found 12/16$2,784

Find flight deals from San Pedro Sula to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Pedro Sula (SAP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$623
(Copa Airlines)

One-way from

$334
(Priceline)

Popular in

November

Cheapest in

April

Average price

$749
Provider with most accurate pricing for San Pedro Sula Ramon Villeda-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Pedro Sula Ramon Villeda-Santiago Arturo Merino Benitez flights.
Search Deals
From San Pedro Sula Ramon Villeda to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Pedro Sula Ramon Villeda to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Pedro Sula to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from San Pedro Sula to Santiago that are best for you.

Fly from

San Pedro Sula

Fly to

Santiago

Route

Depart

Return

Price

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Tue 4/21

1:49 pm-3:00 am

1 stop11h 11m

Santiago Arturo Merino Benitez

Wed 5/13

12:01 am-12:47 pm

1 stop14h 46m

$623

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 5/1

4:07 am-7:23 pm

1 stop13h 16m

Santiago Arturo Merino Benitez

Thu 5/14

11:17 am-11:32 pm

1 stop14h 15m

$623

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 4/24

4:07 am-7:23 pm

1 stop13h 16m

Santiago Arturo Merino Benitez

Thu 4/30

12:38 am-12:47 pm

1 stop14h 09m

$623

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 4/29

4:07 am-10:43 pm

1 stop16h 36m

Santiago Arturo Merino Benitez

Sun 5/3

2:22 am-12:47 pm

1 stop12h 25m

$623

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 5/1

4:07 am-7:23 pm

1 stop13h 16m

Santiago Arturo Merino Benitez

Fri 5/8

4:09 am-12:47 pm

1 stop10h 38m

$623

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 3/25

1:50 pm-3:58 am

1 stop11h 08m

Santiago Arturo Merino Benitez

Fri 4/3

5:17 am-12:47 pm

1 stop10h 30m

$623

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Fri 4/24

8:10 pm-1:25 pm

2 stops15h 15m

Santiago Arturo Merino Benitez

Fri 5/1

6:10 am-6:40 pm

2 stops14h 30m

$624

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Tue 12/30

1:53 pm-3:27 am

1 stop10h 34m

Santiago Arturo Merino Benitez

Tue 1/6

5:20 am-12:40 pm

1 stop10h 20m

$640

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Wed 4/1

4:07 am-8:23 pm

1 stop13h 16m

Santiago Arturo Merino Benitez

Tue 4/7

12:09 am-12:47 pm

1 stop14h 38m

$640

San Pedro SulaSantiago

SAP - SCL

SAPSCL

San Pedro Sula Ramon Villeda

Sun 3/8

1:50 pm-6:00 am

1 stop13h 10m

Santiago Arturo Merino Benitez

Sat 3/14

5:44 am-12:45 pm

1 stop10h 01m

$640

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 20 results
1
2

Compare providers for flights from San Pedro Sula to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Pedro Sula to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Pedro Sula-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Pedro Sula-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Pedro Sula-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Pedro Sula-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Pedro Sula-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Pedro Sula to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Pedro Sula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Pedro Sula to Santiago

How far ahead should I book a flight from San Pedro Sula to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Pedro Sula to Santiago. Price data was last updated on December 12, 2025.

To ensure you get the cheapest price possible for a flight from San Pedro Sula to Santiago, you should look to book at least 15 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Pedro Sula to Santiago?

Currently, March is the cheapest month in which you can book a flight from San Pedro Sula to Santiago (average of $279). Flying from San Pedro Sula to Santiago in December is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAP to SCL?

Find hourly flight availability from San Pedro Sula to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from San Pedro Sula to Santiago in the evening. Doing so could potentially save you 6% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from San Pedro Sula to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from San Pedro Sula to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,490 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Pedro Sula to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Pedro Sula to Santiago?

    Departing from San Pedro Sula to Santiago will take you 11h 11m. The distance from San Pedro Sula to Santiago is about 3557 mi.

  • What are the cheapest airlines flying from San Pedro Sula to Santiago round-trip?

    According to our current data, Avianca ($451), and Copa Airlines ($579) offers the cheapest pricing from San Pedro Sula to Santiago. Avianca is 39% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from San Pedro Sula to Santiago that include hotel bookings?

    Yes. In addition to deals on San Pedro Sula to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Pedro Sula to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Pedro Sula to Santiago.

  • Can I find deals for business class flights from San Pedro Sula to Santiago?

    Yes. Cheapflights offers flight deals from San Pedro Sula to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Pedro Sula to Santiago?

    Currently, March is the cheapest month in which you can book a flight from San Pedro Sula to Santiago (average of $279). Flying from San Pedro Sula to Santiago in December is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top 2 airlines flying from San Pedro Sula to Santiago

Discover the top 2 airlines that operate flights from San Pedro Sula to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$481Average$674FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$579Average$939FlexibilityNo cancel feeOn-time70%

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