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$520+ Cheap flights from Roanoke (ROA) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SCL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Roanoke to Santiago

Cheapest flights from Roanoke to Santiago
Explore the most affordable flight options available from Roanoke to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This LATAM Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:20 am
ROA
-
SCL
2 stops17h 40m
LATAM Airlines
Wed 9/237:45 am
SCL
-
ROA
2 stops17h 05m
LATAM Airlines
Deal found 1/26$1,135

Find flight deals from Roanoke to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars
Provider with most accurate pricing for Roanoke-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Santiago Arturo Merino Benitez flights.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Roanoke to Santiago that are best for you.

Fly from

Roanoke

Fly to

Santiago

Route

Depart

Return

Price

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Sat 2/14

6:00 am-7:40 am

1 stop23h 40m

$520

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Sat 2/14

10:15 am-8:50 am

2 stops44h 35m

$531

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from Roanoke to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Roanoke to Santiago that include hotel bookings?

    Yes. In addition to deals on Roanoke to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Santiago.

  • Can I find deals for business class flights from Roanoke to Santiago?

    Yes. Cheapflights offers flight deals from Roanoke to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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