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$714+ Cheap flights from Roanoke (ROA) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SCL
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Roanoke to Santiago

Best flights from Roanoke to Santiago
Discover carefully curated flight deals from Roanoke to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 16, 2025.

This LATAM Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/511:24 amROA - SCL
2 stops34h 01mLATAM Airlines
Mon 2/911:10 pmSCL - ROA
1 stop22h 09mLATAM Airlines
Deal found 12/13$714
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1310:15 amROA - SCL
2 stops20h 35mUnited Airlines
Tue 1/2010:45 pmSCL - ROA
2 stops17h 24mUnited Airlines
Deal found 12/14$769
This SmartFares deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1311:24 amROA - SCL
1 stop16h 46mLATAM Airlines
Tue 1/209:30 pmSCL - ROA
1 stop15h 09mLATAM Airlines
Deal found 12/14$734

Find flight deals from Roanoke to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$714
(LATAM Airlines)
Provider with most accurate pricing for Roanoke-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Santiago Arturo Merino Benitez flights.
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From Roanoke to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Roanoke to Santiago that are best for you.

Fly from

Roanoke

Fly to

Santiago

Route

Depart

Return

Price

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Thu 2/5

11:24 am-11:25 pm

2 stops34h 01m

Santiago Arturo Merino Benitez

Mon 2/9

11:10 pm-7:19 pm

1 stop22h 09m

$714

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 1/13

11:24 am-6:10 am

1 stop16h 46m

Santiago Arturo Merino Benitez

Tue 1/20

9:30 pm-10:39 am

1 stop15h 09m

$734

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 1/13

10:15 am-8:50 am

2 stops20h 35m

Santiago Arturo Merino Benitez

Tue 1/20

10:45 pm-2:09 pm

2 stops17h 24m

$769

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Compare providers for flights from Roanoke to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Santiago in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Santiago

What is the cheapest time of day to fly from ROA to SCL?

Find hourly flight availability from Roanoke to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s typically best to fly out from Roanoke to Santiago at noon. Doing so could potentially save you 34% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Santiago?

    LATAM Airlines can get you from Roanoke to Santiago in just under 34h 01m. Your travel time can differ by up to . The distance between Roanoke and Santiago is about 4918 mi.

  • Can I find deals for flights from Roanoke to Santiago that include hotel bookings?

    Yes. In addition to deals on Roanoke to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Santiago.

  • Can I find deals for business class flights from Roanoke to Santiago?

    Yes. Cheapflights offers flight deals from Roanoke to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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